Clinical Trials on Brain Malformation

Total 31400 results

University Hospital, Toulouse

Completed

Electromagnetic Navigation During Ultrasound Guided Foam Sclerotherapy for Venous Malformations (SCLERONAV)

Venous Malformation

France
Suez Canal University

Completed

Complications of Ethanol-amine Oleate Intralesional Sclerotherapy

Venous Malformation

Egypt
Unity Health Toronto
Dartmouth College; Cure HHT

Active, not recruiting

Hereditary Hemorrhagic Telangiectasia (HHT) Research Outcomes Registry (HHT)

Hereditary Hemorrhagic Telangiectasia | HHT | Arteriovenous Malformation of Brain

Canada
Centre Hospitalier Universitaire Dijon

Recruiting

Evaluation of Rapid First-line Genome Sequencing for Prenatal Diagnosis of Congenital Malformations in Comparison With Chromosomal Microarray and Exome Sequencing (PRENATOMEultra)

Congenital Malformation

France
Orfagen
FDA Office of Orphan Products Development

Completed

Systemic and Local Diffusion of Ethanol After Administration of Ethanol 96% Formulated in a Gel and Ethanol 98% Solution by the Percutaneous Route, in Patients With Congenital Venous Malformations:Pharmacokinetic, Pharmacodynamic and Clinical Study.

Congenital Venous Malformation

United States, France
Kent State University
Utah State University; The University of Akron

Active, not recruiting

Examining Different Components of Online Acceptance and Commitment Therapy for People With Chiari Malformation

Chronic Pain | Chiari Malformation

United States
Kent State University
Utah State University; Conquer Chiari

Completed

Online Acceptance and Commitment Therapy for Chronic Pain in Sample of People With Chiari Malformation

Chronic Pain | Chiari Malformation

United States
University Hospital, Bonn

Unknown

NIRS Monitoring During Intracranial Interventions (NIRS_ICG)

Subarachnoid Hemorrhage | Intracranial Arteriovenous Malformation

Germany
Yonsei University

Completed

Urodynamic Evaluation in Patients With Anorectal Malformation According to Spinal Cord Abnormalities

Anorectal Malformation

Korea, Republic of
St. Joseph's Hospital and Medical Center, Phoenix

Completed

Dural Graft Equivalent Comparison Trial (DECOMPRESS)

Chiari Malformation

United States
Harvard University Faculty of Medicine
National Institute of Neurological Disorders and Stroke (NINDS); Howard Hughes...

Recruiting

Human Epilepsy Genetics--Neuronal Migration Disorders Study

Epilepsy | Brain Malformation | Cognition Disorder | Neuronal Migration Disorder

United States
Stanford University
Boston Children's Hospital

Recruiting

Trametinib in the Treatment of Complicated Extracranial Arterial Venous Malformation

Arterial Disease | Venous Malformation

United States
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Evaluation of the Accuracy of the Vessel Navigator Tool for Catheterization of Supra-aortic Vessels - ARCHIBALD (ARCHIBALD)

Cardiovascular Diseases | Vascular Diseases | Aortic Aneurysm | Arteriovenous Malformation | Cerebrovascular Diseases

France
National Health Service, United Kingdom

Unknown

Assessing the Effects of Air-cooling on Capillary Malformations

Laser | Capillary Malformation | Skin Cooling

United Kingdom
Johns Hopkins University

Recruiting

Patient Reported Outcomes for Vascular Malformations EmbolizatioN (PROVEN)

Vascular Malformations | VM - Vascular Malformation

United States
First Affiliated Hospital, Sun Yat-Sen University

Unknown

Effect of Dexmedetomidine Combined With Sufentanil for Postoperative Intravenous Analgesia in Neurosurgery

Arteriovenous Malformation

China
yuanli Zhao
Peking University International Hospital

Recruiting

Quantitative Susceptibility Biomarker and Brain Structural Property for Cerebral Cavernous Malformation Related Epilepsy (CRESS)

Epilepsy | Seizures | Seizures, Epileptic | Cavernous Malformation, Cerebral | Cavernous Angioma | Cavernous Hemangioma | Cavernous Hemangioma of Brain

China
University of Zurich

Unknown

Multicenter Validation of the AVICH Score (AVICH)

Intracerebral Hemorrhage | Arterio-venous Malformation
Southern Medical University, China

Recruiting

Clinical Study of the Treatment of Chiari Malformation Combined With Type II Skull Base Depression

Chiari Malformation | Basilar Invagination | Atlantoaxial Dislocation

China
Odense University Hospital
Aarhus University Hospital; University of Southern Denmark

Unknown

Long-term Outcome in Patients With Anorectal Malformations (LOPAM)

Anorectal Malformation
Balt Extrusion

Recruiting

Safety, Performance and Usability of BALT Medical Devices: The EVIDENCE Post Marketing Clinical Follow-up Platform

Peripheral Vascular Diseases | Acute Ischemic Stroke | Intracranial Aneurysm | AVM | AVM - Cerebral Arteriovenous Malformation | Brain Arterial Disease

France, Spain
Shanghai Jiao Tong University School of Medicine

Unknown

the Efficiency of Endoscopic Treatment for Recurrent Small Intestinal Bleeding Due to Gastrointestinal Vascular Malformation

Gastrointestinal Vascular Malformation

China
Beijing Tiantan Hospital

Unknown

Mechanism of Aphasia and Recovery of Language After the Injury of Geschwind's Territory: a Study Based on the Brain Network Analysis

Language | AVM - Cerebral Arteriovenous Malformation

China
Imagine Institute

Completed

Computational Anatomy in Surgery for Childhood Tumours and Malformations (IMAG2)

Tumor | Malformation | Paediatric Surgery | 3D Imaging

France
West China Hospital
Xiamen Health Commission; Xiamen Health and Medical Big Data Center

Completed

A Population-based Study of Drug Exposures and Adverse Pregnancy Outcomes in China (DEEP)

Pregnancy | Congenital Malformation | Drug Exposure

China
University Hospital, Bordeaux

Completed

Cryoablation of Venous Vascular Malformations (CRYOMAV)

Venous Vascular Malformation

France
Centre Hospitalier Universitaire Dijon
Novartis Pharmaceuticals

Recruiting

Assessment of the Efficacy and Safety of Alpelisib (BYL719) in Pediatric and Adult Patients With Megalencephaly-CApillary Malformation Polymicrogyria Syndrome (MCAP) (SESAM)

Megalencephaly-capillary Malformation Polymicrogyria Syndrome (MCAP)

France
Children's Hospital Medical Center, Cincinnati

Unknown

Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies

Tufted Angioma | Microcystic Lymphatic Malformation | Kaposiform Hemangioendotheliomas | Capillary Venous Lymphatic Malformation | Venous Lymphatic Malformation | Mucocutaneous Lymphangiomatosis and Thrombocytopenia | Capillary Lymphatic Arterial Venous Malformations | PTEN Overgrowth Syndrome With... and other conditions

United States
St. Joseph's Hospital and Medical Center, Phoenix
Translational Genomics Research Institute; The Joe Niekro Foundation

Active, not recruiting

Genetics of Arteriovenous Malformations

Arteriovenous Malformation

United States
Assistance Publique - Hôpitaux de Paris

Completed

Genetic and Molecular Abnormalities in Congenital Cystic Adenomatoid Malformations (MAKP)

Congenital Cystic Adenomatoid Malformation (CCAM)

France
Mayo Clinic

Completed

Vascular Anomaly Pathology and Genomics Biopsy Study

Hemangioma | Arteriovenous Malformations | Vascular Malformations | Lymphatic Malformation | Venous Malformation | Vascular Anomaly | Klippel Trenaunay Syndrome

United States
Eisai Co., Ltd.

Completed

A Multicenter, Open-label Study for E7040 in Japanese Subjects With Hypervascular Tumor and Subjects With Arteriovenous Malformation

Hypervascular Tumor and Arteriovenous Malformation

Japan
Nantes University Hospital
MAREP ( Center For Rare Diseases Center Ano-Rectal And Pelvic Abnormalities)

Completed

National Study on the Quality of Life of Patients With Anorectal Malformation (MARQOL)

Anorectal Malformation

France
Fondation Ophtalmologique Adolphe de Rothschild

Terminated

Comparison of Two Protocols of Optimization of X Ray Radiations in Pediatric Interventional Neuroradiology (MINIRAD)

Occlusion or Malformation of a Cerebral Vessel

France
Palvella Therapeutics, Inc.

Recruiting

Study Evaluating the Safety and Efficacy of PTX-022 (QTORIN Sirolimus) in the Treatment of Microcystic Lymphatic Malformations

Microcystic Lymphatic Malformation

United States
Uppsala University

Completed

NASHA/Dx as a Perianal Implant for the Treatment of Persistent Fecal Incontience After Anorectal Malformation

Fecal Incontinence | Anorectal Malformation
Shanghai Jiao Tong University School of Medicine
Changhai Hospital; Peking Union Medical College Hospital; Shanghai Zhongshan... and other collaborators

Completed

the Efficiency of Thalidomide for Recurrent Small Intestinal Bleeding Due to Gastrointestinal Vascular Malformation

Gastrointestinal Vascular Malformation

China
Mayo Clinic

Completed

Genetic Variants in Nicotinamide Adenine Dinucleotide (NAD) Synthesis Pathway

Congenital Malformation | Vacterl Association

United States
University Hospital, Tours
University Hospital, Angers

Recruiting

Topical Sirolimus in Cutaneous Lymphatic Malformations (TOPICAL)

Vascular Malformations | Lymphatic Malformation

France
Hacettepe University

Completed

Investigation of the Effects of Exercise on Patients With Chiari Malformation

Exercise Addiction | Proprioceptive Disorders | Syringomyelia | Chiari Malformation Type I | Coordination and Balance Disturbances | Basilar Invagination | Atlanto-Axial Subluxation

Turkey
St. Joseph's Hospital and Medical Center, Phoenix

Terminated

Effect of Oral Propranolol on mRNA Expresssion in Symptomatic Cavernous Malformation

Cerebral Cavernous Malformations

United States
Institut National de la Santé Et de la Recherche...

Recruiting

National Evaluation of Patients With PIK3CA-Related Overgrowth Spectrum (PROS) (COSY)

Vascular Malformations | PIK3CA-related Overgrowth Spectrum | Megalencephaly | Lymphatic Malformation | CLOVES Syndrome | Venous Malformation | Klippel Trenaunay Syndrome | MCAP | Macrodactyly

France
Palvella Therapeutics, Inc.

Not yet recruiting

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study Evaluating Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations (SELVA)

Microcystic Lymphatic Malformation

United States
Hospital Ruber Internacional
Zogenix, Inc.

Recruiting

Fenfluramine for the Treatment of Different Types of Developmental and Epileptic Encephalopathies: a Pilot Trial Exploring Epileptic and Non-epileptic Outcomes (FENDEEP)

Refractory Epilepsy | STXBP1 Encephalopathy With Epilepsy | SYNGAP1 Encephalopathy | Inv Dup(15) Encephalopathy | Multifocal or Bilateral Malformations of Cortical Development | Continuous Spike and Waves During Slow Sleep

Spain
University of Chicago
Johns Hopkins University; Mayo Clinic; National Institute of Neurological Disorders... and other collaborators

Completed

CASH (Cavernous Angiomas With Symptomatic Hemorrhage) Trial Readiness

Cerebral Cavernous Malformation | Cavernous Angioma | Cavernoma | CCM | Cerebral Cavernous Malformations 1 | Cerebral Cavernous Malformations 2 | Cerebral Cavernous Malformations 3

United States
Universitaire Ziekenhuizen KU Leuven

Active, not recruiting

Can we Use Resting-state fMRI and CSD Fiber Tractography for Presurgical Mapping?

Epilepsy | Brain Tumor | Vascular Malformations, Brain | Brain Pathology

Belgium
Erasmus Medical Center

Recruiting

The COllaborative Neonatal Network for the First CPAM Trial (CONNECT)

Congenital Pulmonary Airway Malformation

Netherlands
West China Hospital

Recruiting

Use of Bleomycin in the Sclerotherapy of Lymphatic Malformations for Pediatric Patients

Lymphatic Malformation

China
Nanjing Children's Hospital

Recruiting

A Prospective Study on the Treatment of cLM Based on ICG Imaging

Lymphatic Malformation

China
Protara Therapeutics

Recruiting

Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age (STARBORN-1)

Lymphatic Malformation

United States

Clinical Trials on Brain Malformation

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in South Africa

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations