Clinical Trials on Brain Surgery

Total 36532 results

University Hospital, Basel, Switzerland

Terminated

Effect of Cobicistat Versus Ritonavir Boosting on the Brain Permeation of Darunavir in HIV-infected Individuals

AIDS-related Dementia Complex

Switzerland
Institute for Neurodegenerative Disorders

Completed

Evaluation of [123I]MNI-420 and SPECT as a Marker of the Adenosine A2a Receptor in PD, HD and Healthy Subjects. (MNI-420)

Parkinson Disease | Huntington Disease

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft Tissue Sarcoma

Sarcoma | Unspecified Childhood Solid Tumor, Protocol Specific | Brain and Central Nervous System Tumors | Neuroblastoma

United States
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Prevalence of Cerebral Small Vessel Disease in HIV Infected Patients (MICROBREAK1)

HIV Seropositivity

France
University College, London

Completed

Auditory Rehabilitation in Stroke Patients With Auditory Processing Disorders

Stroke | Auditory Processing Disorder, Central

United Kingdom
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Strong Heart Study

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Hypertension | Obesity | Diabetes Mellitus | Atherosclerosis | Asthma | Carotid Artery Diseases | Hypercholesterolemia
Xuanwu Hospital, Beijing
West China Hospital; Qilu Hospital of Shandong University; Nanfang Hospital of... and other collaborators

Unknown

New Covered Stent (Willis) for the Endovascular Reconstruction of Intracranial Vessel Wall Defects Registry (COVER)

Aneurysm, Intracranial | Carotid-Cavernous Sinus Fistula

China
Amsterdam UMC, location VUmc

Completed

GH and Cardiovascular Risk Factors

Cardiovascular Diseases | Physical Activity | Metabolic Syndrome | Growth Hormone Deficiency | Cognition

Netherlands
Sergiusz Jozwiak
Medical University of Vienna; Charite University, Berlin, Germany; Institut National... and other collaborators

Unknown

Long-term, Prospective Study Evaluating Clinical and Molecular Biomarkers of Epileptogenesis in a Genetic Model of Epilepsy - Tuberous Sclerosis Complex (EPISTOP)

Epilepsy | Tuberous Sclerosis Complex | TSC

Poland, Austria, Belgium, Czech Republic, France, Germany, Italy, Netherlands
Korea Otsuka Pharmaceutical Co., Ltd.
Otsuka Pharmaceutical Co., Ltd.

Completed

Aripiprazole in Children and Adolescents With Chronic Tic Disorder or Tourette's Disorder

Tourette's Disorder | Chronic Motor or Vocal Tic Disorder

Korea, Republic of
Rennes University Hospital

Terminated

Study of Povidone Iodine to Reduce Pulmonary Infection in Head Trauma and Cerebral Hemorrhage in Intensive Care Unit (SPIRIT-ICU)

Ventilator Associated Pneumonia

France
Pfizer
Medivation, Inc.

Completed

A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function

Alzheimer's Disease | Huntington's Disease

United States
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Systematic Care for Informal Caregivers of Dementia Patients: An Efficient Approach?

Dementia | Alzheimer Disease | Lewy Body Disease | Dementia, Vascular

Netherlands
Royal Brisbane and Women's Hospital

Completed

Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multiple System Atrophy

Parkinson's Disease | Multiple System Atrophy | Orthostatic Hypotension

Australia
National Cancer Institute (NCI)

Completed

Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Recurrent Ovarian Carcinoma | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Renal Cell Carcinoma | Stage III Renal Cell Cancer | Stage IV Skin Melanoma | Recurrent Non-Small Cell... and other conditions

Canada
Karamanoğlu Mehmetbey University

Recruiting

Physical Activity in Children With Wolff-Parkinson-White Syndrome

Wolff-Parkinson-White Syndrome

Turkey
Istituto Auxologico Italiano
IRCCS Istituto Neurologico Carlo Besta

Recruiting

Gait and Balance Impairment in Rare and Very Rare Neurological Diseases (GALVANISE)

Multiple Sclerosis | Healthy | Parkinson Disease | Healthy Aging | Peripheral Neuropathy | Rare Diseases

Italy
Yale University

Recruiting

Intestinal Immunity in Neurologic Disease

Multiple Sclerosis | Parkinson Disease | REM Sleep Behavior Disorder

United States
Sobet AG
La Tour Hospital; Klinikum Klagenfurt am Wörthersee; Krankenhaus der Elisabethinen... and other collaborators

Recruiting

Low-Energy Ultrasound, Electrical and Magnetic Field Stimulation in Therapy-Resistant Myofascial Pain Syndrome

Myofascial Pain Syndrome - Lower Back | Myofascial Pain Syndrome - Neck | Myofascial Pain Syndrome - Tension Headache

Austria, Switzerland
Instituto de Biomecanica de Valencia
Hospital General Universitario de Valencia; Asociación Parkinson Valencia (https... and other collaborators

Recruiting

Health Indicators and Patient Reported Outcomes. Identification of Significative Items Aimed at Improving Health Care Procceses. (OUTCOMES)

Stroke | COVID-19 | Diabetes Mellitus | Parkinson Disease | Chronic Obstructive Pulmonary Disease (COPD)

Spain
University of New Mexico
University of California, San Francisco

Recruiting

Functional Magnetic Resonance Imaging (fMRI) Vascular Reactivity in Cerebral Cavernous Malformations (CCM)

Cerebral Cavernous Malformation

United States
National University Hospital, Singapore

Recruiting

CARTALL: Chimeric-Antigen Receptor (CAR) T-Cell Therapy for Relapsed/ Refractory T-Lineage Acute Lymphoblastic Leukaemia

Lymphoblastic Leukemia, Acute, Childhood | Lymphoblastic Leukemia | Lymphoblastic Leukemia, Acute Adult | Lymphoblastic Leukemia in Children | CAR | CAR T-Cell-Related Encephalopathy Syndrome | Refractory Leukemia

Singapore
National University Hospital, Singapore

Recruiting

ALaCART-B: Acute Leukemia and Chimeric Antigen Receptor-T Cell Therapy for B-lymphoblastic Leukemia. (ALaCART)

Lymphoblastic Leukemia, Acute, Childhood | Lymphoblastic Leukemia | Lymphoblastic Leukemia, Acute Adult | Lymphoblastic Leukemia in Children | CAR | CAR T-Cell-Related Encephalopathy Syndrome

Singapore
University of Roma La Sapienza

Recruiting

Clinical Study on Circadian Genes Dysregulation in Patients With Glucocorticoid Disorders (CHROnOS)

Cushing Syndrome | Adrenal Insufficiency | Cushing Disease | Addison Disease

Italy
IntraBio Inc

Recruiting

N-Acetyl-L-Leucine for Ataxia-Telangiectasia (A-T)

Ataxia Telangiectasia | Louis Bar Syndrome

Spain, United States, Germany, United Kingdom
Fundació Institut de Recerca de l'Hospital de la...
Instituto de Salud Carlos III

Completed

Identification and Clinical Relevance of an Oxytocin Deficient State (CRH Study)

Pituitary Diseases | Hypothalamic Diseases | Hypopituitarism | Social Isolation | Panhypopituitarism | Psychological Disorder | Central Diabetes Insipidus | Oxytocin Deficiency

Spain
McGill University Health Centre/Research Institute...
Weston Brain Institute

Completed

Effect of Long-acting Levodopa on Obstructive Sleep Apnea in Parkinson's Disease

Parkinson's Disease | Obstructive Sleep Apnea

Canada
McGill University Health Centre/Research Institute...
Canadian Institutes of Health Research (CIHR); American Thoracic Society

Completed

Cognition and Obstructive Sleep Apnea in Parkinson's Disease, Effect of Positive Airway Pressure Therapy (COPE-PAP)

Parkinson's Disease | Obstructive Sleep Apnea

Canada
Marinella Temprosa
National Institute on Aging (NIA)

Enrolling by invitation

The Diabetes Prevention Program Outcomes Study AD/ADRD Project (DPPOS-4)

Diabetes | Dementia | PreDiabetes | Alzheimer Disease | Dementia, Vascular

United States
Brigham and Women's Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Nurses' Health Study (Cardiovascular Component)

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Diabetes Mellitus | Angina Pectoris | Menopause | Cerebrovascular Accident | Pulmonary Embolism | Postmenopause
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Effect of Galantamine on Inflammation and Cognition (CHI)

HIV Associated Cognitive Motor Complex

United States
Centre de Recherche de l'Institut Universitaire...
Canadian Institutes of Health Research (CIHR)

Completed

Evaluation of a Cognitive Psychophysiological Treatment for Tourette Syndrome and Tic Disorders

Tourette Syndrome | Tourette Syndrome in Children | Tic Disorder, Chronic Motor or Vocal

Canada
Vanderbilt University Medical Center

Completed

Sensory Symptoms in Tourette Syndrome and Obsessive-Compulsive Disorder (SenST-Plus)

Obsessive-Compulsive Disorder | Tourette Syndrome | Sensory Disorders

United States
University Hospital, Bordeaux

Completed

Impact of Changes in the Use of Care and Reorganization of the Healthcare System Linked to the Covid-19 Outbreak on the Quality of Care Pathways of Patients Suffering From Acute Myocardial Infarction and Stroke in Aquitaine (AVICOVID) (AVICOVID)

Stroke | Coronavirus Disease 2019 | Acute Myocardial Infarction

France
Novo Nordisk A/S

Completed

Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Various Degrees of Impaired Renal Function Compared to Subjects With Normal Renal Function

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Germany
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pulmonary Hypertension, Hypoxia and Sickle Cell Disease

Sickle Cell Anemia | Pulmonary Hypertension | Cerebrovascular Disease | Chuvash Polycythemia

United States, Russian Federation
National Institute of Mental Health (NIMH)

Terminated

Brain Tissue Collection for Neuropathological Studies

Depression | Brain Diseases | Schizophrenia | Anxiety Disorders | Bipolar Disorder | Tourette's Syndrome

United States
University of Erlangen-Nürnberg Medical School

Unknown

Stratifying Risk for Intracerebral Haemorrhage (NEW_STRATEGI)

Coagulation Protein Disorders | Preterm Birth | Coagulation Disorder Neonatal

Germany
University of Texas Southwestern Medical Center

Withdrawn

Vaccine Therapy and GM-CSF in Treating Patients With CNS Lymphoma

Lymphoma | Small Intestine Cancer | Brain and Central Nervous System Tumors | Lymphoproliferative Disorder

United States
National Institute of Allergy and Infectious Diseases...
National Institutes of Health (NIH)

Terminated

Vaccine Study for Tick-Borne Encephalitis Virus (TBEV) (TBEV)

Tick-Borne Disease | Encephalitis, Tick-Borne | Tick-Borne Encephalitis | Glycoprotein E, Flavivirus | NSI Protein, Flavivirus

United States
University of Utah
Marquette University

Completed

TicHelper: A Computerized Comprehensive Behavioral Intervention for Tics (CBIT)

Tourette's Disorder | Persistent (Chronic) Motor or Vocal Tic Disorder

United States
NHS Tayside
University of Dundee

Completed

Response of Individuals With Ataxia-Telangiectasia to Metformin and Pioglitazone (RAMP)

Ataxia-Telangiectasia

United Kingdom
Beth Israel Deaconess Medical Center
Merz Pharmaceuticals

Withdrawn

Incobotulinum Toxin A for Sialorrhea in Parkinson's Disease (PD)/Parkinsonism and Amyotrophic Lateral Sclerosis (ALS) (Xeomin)

Parkinson Disease | Amyotrophic Lateral Sclerosis

United States
Molecular NeuroImaging
Life Molecular Imaging SA

Completed

Evaluation of [18F]MNI-815 as a Potential PET Radioligand for Imaging Tau Protein in the Brain of Patients With Tauopathies

Alzheimer's Disease (AD) | Progressive Supranuclear Palsy (PSP) | Frontal Temporal Dementia (FTD) | Cortical Basal Syndrome (CBS)

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin

Testicular Germ Cell Tumor | Ovarian Cancer | Brain and Central Nervous System Tumors | Teratoma | Extragonadal Germ Cell Tumor

United States
University of Michigan

Completed

Magnetic Resonance Spectroscopy, Perfusion, and Diffusion Tensor Imaging in Neuropsychiatric Lupus

Neuropsychiatric Systemic Lupus Erythematosus

United States
NYU Langone Health

Withdrawn

Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor

Sarcoma | Brain and Central Nervous System Tumors | Neuroblastoma | Retinoblastoma

United States, Canada, Argentina
St. Jude Children's Research Hospital
National Cancer Institute (NCI); Children's Hospital of Philadelphia

Completed

Study for Treatment of Cancer in Children With Ataxia-telangiectasia

Ataxia-Telangiectasia

United States
Johns Hopkins Bloomberg School of Public Health
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Sleep Heart Health Study (SHHS) Data Coordinating Center (SHHS)

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Sleep Apnea Syndromes | Lung Diseases | Hypertension | Cerebrovascular Accident
China Medical University Hospital

Unknown

Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants

Retinopathy of Prematurity | Intraventricular Hemorrhage | Infant, Premature | Leukomalacia, Periventricular

Taiwan

Clinical Trials on Brain Surgery

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Finland

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations