Clinical Trials on Brain Tumor-Glioma

Total 45910 results

Andrew B Lassman, MD
Pfizer; AEterna Zentaris

Completed

Perifosine and Torisel (Temsirolimus) for Recurrent/Progressive Malignant Gliomas

Glioblastoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Brain Tumor, Recurrent | Mixed Glioma

United States
University of Texas Southwestern Medical Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Clinical Development of Cancer-Specific MRS Biomarkers in Malignant Gliomas

Malignant Gliomas | Astrocytomas | Oligodendrogliomas

United States
Ivy Brain Tumor Center
GlaxoSmithKline

Recruiting

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Glioblastoma | Brain Tumor | GBM | Brain Neoplasms, Adult, Malignant

United States
Northwest Biotherapeutics

Active, not recruiting

Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer (GBM)

Glioma | Glioblastoma | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | GBM | Grade IV Astrocytoma

United States, Germany, Canada, United Kingdom
Nicklaus Children's Hospital f/k/a Miami Children...

Terminated

Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Embryonal Tumor With Abundant Neuropil and True Rosettes | Metastatic Malignant Neoplasm to the Leptomeninges

United States
Northwell Health
Olympus Corporation

Recruiting

Pilot Study Evaluating the Optimization of the ORBEYE Blue Light Filter During Fluorescence-Guided Resection of Gliomas

Malignant Glioma of Brain

United States
NaviFUS Corporation
Chang Gung Memorial Hospital

Completed

Safety of BBB Disruption Using NaviFUS System in Recurrent Glioblastoma Multiforme (GBM) Patients

Glioma | Neoplasms | Glioblastoma | Neoplasms, Nerve Tissue | Brain Tumor | Glioblastoma Multiforme

Taiwan
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Pilot Immunotherapy Trial for Recurrent Malignant Gliomas

Malignant Glioma of Brain

United States
Philogen S.p.A.

Completed

Safety and Efficacy of L19TNF in Patients With Isocitrate Dehydrogenase (IDH) Wildtype WHO Grade III / IV Glioma at First Relapse (GLIOMOON)

Glioma of Brain

Switzerland
Cancer Trials Ireland
Royal College of Surgeons, Ireland

Terminated

Blood Biomarker Signature in Glioma

Glioma of Brain

Ireland
Nationwide Children's Hospital
Pfizer

Not yet recruiting

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | WHO Grade III Glioma | WHO Grade IV Glioma | Infant Type Hemispheric Glioma | Diffuse Midline Glioma, H3K27-altered

United States, Australia, Canada, Germany, Netherlands
M.D. Anderson Cancer Center

Withdrawn

Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MR

Cancer | Glioblastoma | Brain Metastases | Gliomas

United States
Washington University School of Medicine

Recruiting

Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors

Glioma | Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Oligodendroglioma | Pilocytic Astrocytoma | Mixed Oligoastrocytoma | Mixed Glioma | Optic Glioma

United States
Center Trials & Treatment
BioGene Pharmaceutical Inc.

No longer available

An Expanded Access Program of Ipilimumab for Patients With Glioblastomas and Gliomas

Glioblastoma | Glioma of Brain

Bosnia and Herzegovina, Albania, Bulgaria, Croatia, Romania, Russian Federation, Serbia, Switzerland
Northwell Health

Recruiting

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

Glioblastoma | Brain Cancer | Brain Tumor | GBM | Brain Neoplasm | Brain Neoplasm, Malignant | EGFR Gene Overexpression

United States
Nationwide Children's Hospital
PTC Therapeutics

Active, not recruiting

A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma

High Grade Glioma | Diffuse Intrinsic Pontine Glioma

United States
Helsinn Healthcare SA
Labcorp Drug Development Inc

Withdrawn

Study With Infigratinib in Subjects With Advanced Solid and CNS Tumors or Recurrent or Progressive Low-Grade Glioma With Selected FGFR1-3 Alterations (NEWEL)

Advanced Solid Tumor | CNS Tumor | Recurrent WHO Grade II Glioma

United States, Canada, Germany
National Cancer Institute (NCI)

Completed

A Phase I/II Trial of BMS-247550 for Treatment of Patients With Recurrent High-Grade Gliomas

Adult Anaplastic Astrocytoma | Adult Giant Cell Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Amsterdam UMC, location VUmc

Recruiting

A Phase II/III Study of High-dose, Intermittent Sunitinib in Patients With Recurrent Glioblastoma Multiforme (STELLAR)

Glioblastoma | Glioblastoma Multiforme | GBM | Glioblastoma, Adult | Recurrent Brain Tumor

Netherlands
Beth Israel Medical Center
St. Luke's-Roosevelt Hospital Center

Terminated

Stem Cell Radiotherapy and Temozolomide for Newly Diagnosed High-grade Glioma (STRONG)

Glioblastoma | Malignant Glioma | Anaplastic Astrocytoma | Brain Tumors

United States
University of Michigan Rogel Cancer Center

Terminated

Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations

Glioma | High Grade Glioma | Pontine Tumors

United States
University Hospital, Strasbourg, France

Recruiting

Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy (PLGG - MEKTRIC)

Pleomorphic Xanthoastrocytoma | Grade 1 Glioma | Mixed Glio-neuronal Tumors

France
Sue O'Dorisio

Completed

Safety of 68Ga-DOTA-tyr3-Octreotide PET in Diagnosis of Solid Tumors (GA-68)

Neuroendocrine Tumors | Medulloblastoma | Neuroblastoma | Carcinoid Tumors

United States
University of Alberta
Capital Health, Canada

Completed

The Safety and Efficacy of DCA for the Treatment of Brain Cancer

Malignant Gliomas, Glioblastoma Multiforme

Canada
University Hospital, Geneva

Active, not recruiting

Pembrolizumab in Association With the IMA950/Poly-ICLC for Relapsing Glioblastoma (IMA950-106)

Glioblastoma Multiforme | Glioblastoma Multiforme of Brain | Glioma of Brain | Glioblastoma, Adult

Switzerland
University of California, San Francisco
Tilburg University

Terminated

Feasibility And Efficacy Of An iPad-Based Cognitive Rehabilitation Program In Brain Tumor Patients

Glioma

United States
University of Miami

Completed

Metabolic Tumor Volumes in Radiation Treatment of Primary Brain Tumors

Brain Tumor | Glioblastoma Multiforme

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Mind-Body Intervention in Glioma Couples

Glioblastoma | Malignant Glioma | WHO Grade III Glioma | Metastatic Malignant Neoplasm in the Brain | Low Grade Glioma | Partner

United States
Children's National Research Institute

Recruiting

Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

Diffuse Intrinsic Pontine Glioma | Brainstem Glioma

United States
St. Jude Children's Research Hospital

Completed

Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)

Diffuse Intrinsic Pontine Glioma | High-grade Glioma

United States
Children's Cancer and Leukaemia Group

Completed

Combination Chemotherapy, Surgery or Radiation Therapy, and Peripheral Stem Cell Transplant in Treating Patients With Recurrent Medulloblastoma or Primitive Neuroectodermal and Pineal Tumors

Brain and Central Nervous System Tumors

United Kingdom, Ireland
University Hospital, Montpellier
National Development and Research Institutes, Inc.

Recruiting

Measure of the Potential Evoked by Electric Stimulation (PE&CE)

Low Grade Glioma of Brain

France
National Cancer Institute (NCI)

Recruiting

Study of Zotiraciclib for Recurrent High-Grade Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

Cancer | Brain Tumor

United States
University of Florida
National Institutes of Health (NIH)

Completed

Study of the Safety and Efficacy of Dichloroacetate (DCA) in Glioblastoma and Other Recurrent Brain Tumors

Glioblastoma | Brain Tumor

United States
National Cancer Institute (NCI)

Recruiting

Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors

Recurrent Malignant Glioma | Recurrent Medulloblastoma | Refractory Malignant Glioma | Refractory Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm | Refractory Diffuse Intrinsic Pontine...

United States, Canada
Universitaire Ziekenhuizen KU Leuven

Completed

Advanced MR Techniques in Detection of Tumor Infiltration and Grading in Gliomas

Gliomas

Belgium
M.D. Anderson Cancer Center

Completed

Measuring Non-Enhancing Glioblastoma Progression

Glioblastoma | Brain Tumor

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Recurrent Childhood Medulloblastoma | Childhood Choroid Plexus Tumor | Childhood Ependymoblastoma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma | Childhood Medulloepithelioma | Recurrent Childhood Anaplastic Astrocytoma | Recurrent... and other conditions

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
Millennium Pharmaceuticals, Inc.

Completed

Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland Astrocytoma | Recurrent... and other conditions

United States
National Cancer Institute (NCI)

Completed

Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Childhood Malignant Germ Cell Tumor | Recurrent... and other conditions

United States
Emory University
National Cancer Institute (NCI)

Recruiting

Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors

Malignant Brain Glioma

United States
Children's Hospital Los Angeles
Dana-Farber Cancer Institute

Active, not recruiting

Study of MEK162 for Children With Low-Grade Gliomas

Soft Tissue Neoplasms | Low-Grade Gliomas | Malignant Neoplasms, Brain

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Treovir, LLC; American Lebanese Syrian Associated...

Not yet recruiting

HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma

Neoplasms | Malignant Glioma of Brain | Glioblastoma Multiforme | High Grade Glioma | Giant Cell Glioblastoma | High-grade Glioma | Anaplastic Astrocytoma of Brain | Anaplastic Glioma

United States
Weill Medical College of Cornell University

Terminated

Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22

Glioblastoma Multiforme | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Brain Stem Glioma | Pilomyxoid Astrocytoma | Glioma of Brainstem | Fibrillary Astrocytoma of Brain | Mixed Oligodendroglioma-Astrocytoma

United States
University of Alabama at Birmingham

Terminated

FET-PET/MRI for Surgical Assessment of Pediatric Brain Tumors

Pediatric Brain Tumors

United States
University of California, San Francisco

Completed

Pilot Study of Safety and Toxicity of Acquiring Hyperpolarized Carbon-13 Imaging in Children With Brain Tumors

Pediatric Brain Tumors

United States
Nationwide Children's Hospital

Not yet recruiting

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

High Grade Glioma | Recurrent Medulloblastoma | Diffuse Intrinsic Pontine Glioma

United States
Medical University of Vienna

Unknown

Disease Progression and Treatment-induced Alterations in Glioblastoma

Brain Tumor

Austria
University of California, San Francisco
National Institute of Neurological Disorders and Stroke (NINDS); The Chad-Tough... and other collaborators

Recruiting

Combination Therapy for the Treatment of Diffuse Midline Gliomas

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent WHO Grade III Glioma | WHO Grade III Glioma

United States, Netherlands, Israel, Australia, New Zealand, Switzerland
Burzynski Research Institute

Completed

Antineoplaston Therapy in Treating Children With Brain Tumors

Childhood Brain Tumors

United States

Clinical Trials on Brain Tumor-Glioma

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