Clinical Trials on CAR-T Cell Immunotherapy

Total 1970 results

National Cancer Institute (NCI)
NRG Oncology

Terminated

Testing the Addition of an Anti-cancer Immune Therapy Drug (Nivolumab) to the Usual Chemotherapy Treatment (Cisplatin or Carboplatin With Gemcitabine) for Recurrent or Metastatic Nasopharyngeal Cancer

Recurrent Nasopharyngeal Carcinoma | Stage IV Nasopharyngeal Carcinoma AJCC v8 | Metastatic Nasopharyngeal Carcinoma | Metastatic Nasopharyngeal Keratinizing Squamous Cell Carcinoma | Metastatic Nasopharyngeal Nonkeratinizing Carcinoma | Metastatic Nasopharyngeal Undifferentiated Carcinoma | Nasopharyngeal... and other conditions

United States, Canada, China, Singapore
Loren Mell, MD
Merck Sharp & Dohme LLC

Recruiting

Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer

Cancer | Head and Neck Squamous Cell Carcinoma | Oral Cancer | Tumor | Oropharynx Cancer | Cancer of Head and Neck | Oropharyngeal Cancer | Cancer, Advanced | Cancer, Metastatic | Tumor Metastasis | Tumor Recurrence | Tumor Neck | Oropharynx Cancer, Stage III | Oropharynx Cancer, Recurrent | Oropharynx Cancer, Metastatic

United States
Ascentage Pharma Group Inc.

Recruiting

Study of Safety, Pharmacokinetic and Efficacy of APG-5918 in Advanced Solid Tumors or Lymphomas

Sarcoma | Nasopharyngeal Carcinoma | Gastric Cancer | B Cell Lymphoma | Mesothelioma | Non Hodgkin Lymphoma | Ovarian Clear Cell Carcinoma | Epithelioid Sarcoma | Castrate Resistant Prostate Cancer

United States
Maastricht Radiation Oncology
Maastricht University Medical Center

Recruiting

Vestibular Schwannoma Organoids

Vestibular Schwannoma

Netherlands
Medical College of Wisconsin

Recruiting

Evaluating Pre-Treatment Vestibular Physical Therapy Rehab for Patients With Vestibular Schwannomas (VS PREHAB)

Vestibular Schwannoma

United States
Karolinska Institutet

Completed

Gamma Knife Radiosurgery vs Initial Conservative Treatment for Vestibular Schwannoma Patients With Preserved Hearing, a Prospective Randomized Study

Vestibular Schwannoma

Sweden
Northwell Health
Feinstein Institute for Medical Research; Hofstra North Shore

Suspended

Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Vestibular Schwannoma

Vestibular Schwannoma

United States
Vanderbilt University Medical Center
National Institute on Deafness and Other Communication Disorders (NIDCD)

Withdrawn

Evaluating the Pre-Positioning Frame for Robotic Acoustic Neuroma Removal Surgery (PPF)

Acoustic Neuroma

United States
Lund University

Withdrawn

Gentamicin Treatment Prior to Schwannoma Surgery - No Residual Function

Vestibular Schwannoma

Sweden
University College, London
University College London Hospitals

Unknown

Novel Multimodality Imaging for Navigation in Skull Base Surgery (SBN)

Vestibular Schwannoma

United Kingdom
Assiut University

Unknown

Endoscopic-assisted Microsurgical Removal of Cerebellopontine Angle Lesions

Cerebellopontine Angle Tumor
University of Southern California

Not yet recruiting

Role of ChatGPT in Vestibular Schwannoma Management

Vestibular Schwannoma
Medical University of Vienna

Recruiting

MR Fingerprinting for Vestibular Schwannomas

Vestibular Schwannoma

Austria
Mayo Clinic

Completed

Microscopic Fluorescence-guided Vestibular Schwannoma Resection Using Fluorescein Sodium and YELLOW 560

Vestibular Schwannoma

United States
Haukeland University Hospital

Completed

Vestibular Schwannoma - Radiosurgery or Expectation: V-REX. (V-REX)

Vestibular Schwannoma

Norway
Stanford University
Baylor College of Medicine; University of Iowa; Weill Medical College of Cornell... and other collaborators

Completed

Subtotal Resection of Large Acoustic Neuromas With Possible Stereotactic Radiation Therapy

Neuroma, Acoustic

United States
Lund University

Withdrawn

Gentamicin Treatment Prior to Schwannoma Surgery - Residual Function

Vestibular Schwannoma

Sweden
Taipei Medical University Shuang Ho Hospital

Unknown

Impact of Shared Decision-Making With Decision Aids on Acoustic Neuroma Treatment Choice: A Randomized Controlled Trial

Neuroma, Acoustic
University Hospital, Strasbourg, France

Unknown

Clinical and Radiological Evaluation of Acoustic Neuromas With Spontaneous Shrinkage

Neuroma, Acoustic

France
Seoul National University Hospital

Unknown

Response Prediction After GKS in Patients With Vestibular Schwannoma Using DCE MR Imaging

Vestibular Schwannoma
Central Hospital, Nancy, France
University of Lorraine

Unknown

Preoperative Vestibular Rehabilitation Effectiveness After Vestibular Schwannoma Surgery (ReveSTAN)

Vestibular Schwannoma

France
Adana Numune Training and Research Hospital

Completed

Atopic Diseases & Human Papilloma Virus

Human Papilloma Virus | Atopic Asthma | Atopic Disorders

Turkey
Turnstone Biologics, Corp.
Takeda

Terminated

Study of TBio-6517 Given Alone or in Combination With Pembrolizumab in Solid Tumors (RAPTOR)

Renal Cell Carcinoma | Cervical Cancer | Solid Tumor | Mesothelioma | Melanoma (Skin) | Oropharynx Cancer | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Microsatellite Stable Colorectal Cancer | Cutaneous Squamous Cell Carcinoma

United States, Canada, Korea, Republic of
Northwestern University
Northwestern Memorial Hospital

Recruiting

Training Swallowing Initiation During Expiration

Head and Neck Cancer | Dysphagia | Oropharyngeal Dysphagia | Oropharynx Squamous Cell Carcinoma

United States
Dana-Farber Cancer Institute

Withdrawn

GROW (Glioma Specialists Reaching Out With Support) Support

Low-grade Glioma | Survivorship | Care Giving Burden

United States
Medical University of Vienna

Completed

Triamcinolone Levels in Cochlear Perilymph, Lateral Canal and CSF

Vestibular Schwannoma

Austria
Rigshospitalet, Denmark

Unknown

RGD PET/MRI in Sporadic Vestibular Schwannoma

Acoustic Neuroma

Denmark
Central Hospital, Nancy, France
University of Lorraine

Unknown

Vestibular Schwannoma and Psychological Factors

Vestibular Schwannoma

France
Ramathibodi Hospital

Unknown

Stereotactic Radiation in Vestibular Schwannoma

Vestibular Schwannoma
National Cancer Institute (NCI)

Completed

Chemotherapy Plus Sargramostim in Treating Patients With Refractory Myeloid Cancer

Thrombocytopenia | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13... and other conditions

United States
Sun Yat-sen University
Doublle Bioproduct Inc

Unknown

Trial of E10A in Head and Neck Cancer

Nasopharyngeal Carcinoma | Head and Neck Squamous Carcinoma

China
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation... and other conditions

United States
University of Minnesota
American Academy of Otolaryngology-Head and Neck Surgery Foundation; American...

Completed

Observational Study of Swallowing Function After Treatment of Advanced Laryngeal Cancer

Laryngeal Cancer | Squamous Cell Carcinoma

United States
Sanford Health
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab in Combination With CRT for LA-SCCHN

Head and Neck Cancer | Laryngeal Cancer | Oropharynx Cancer | Oral Cavity Cancer | Larynx Cancer | Squamous Cell Carcinoma | Hypopharynx Cancer

United States
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Very Intense Radiotherapy-Chemotherapy Regimen in Advanced HNSCC

Oral Cancer | Oropharynx Cancer | Larynx Cancer | Hypopharynx Cancer

France
Groupe Oncologie Radiotherapie Tete et Cou

Completed

Accelerated Radiotherapy and Concomitant Chemo-radiotherapy in HNSCC

Oral Cancer | Oropharynx Cancer | Larynx Cancer | Hypopharynx Cancer

France
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of SI-B003 and BL-B01D1+SI-B003 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors

Nasopharyngeal Carcinoma | Non-small Cell Lung Cancer

China
National Cancer Institute (NCI)

Completed

Bortezomib With or Without Irinotecan in Treating Patients With Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Tongue Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Squamous Cell Carcinoma of the Paranasal Sinus... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck Cancer

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive)... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Takeda; Amgen

Recruiting

Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Philadelphia Chromosome Positive | Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia | t(9;22) | Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | BCR-ABL1...

United States
UNICANCER
Merck Sharp & Dohme LLC; National Cancer Institute, France; Ligue contre le cancer...

Completed

Secured Access to Pembrolizumab for Patients With Selected Rare Cancer Types (AcSé)

Sarcoma | Neoplasms, Germ Cell and Embryonal | Carcinoma, Neuroendocrine | Ovarian Neoplasm | Central Nervous System Neoplasm | Thyroid Neoplasm | NK/T-cell Lymphoma

France
ClinAssess
Sanofi; Merck Sharp & Dohme LLC

Completed

Docetaxel, Cisplatin (TP) + Radiation +/- Cetuximab in Larynx Carcinoma (CA) (DeLOS II)

Squamous Cell Carcinoma of the Hypopharynx | Larynx Carcinoma

Germany, Austria
Roswell Park Cancer Institute
National Cancer Institute (NCI); Cleveland BioLabs, Inc.

Withdrawn

Entolimod in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer Receiving Cisplatin and Radiation Therapy

Mucositis | Tongue Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Squamous Cell Carcinoma of the Paranasal... and other conditions
Marcelo Bonomi

Recruiting

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Fludarabine Phosphate, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Peripheral Blood Stem Cell Transplant, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Malignancies

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

Capecitabine and Lapatinib Ditosylate in Treating Patients With Squamous Cell Cancer of the Head and Neck

Head and Neck Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent... and other conditions

United States
University Health Network, Toronto
Novartis

Terminated

A Study of Nilotinib in Growing Vestibular Schwannomas

Growing Vestibular Schwannomas

Canada
Duke University
National Cancer Institute (NCI)

Completed

Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors

Sarcoma | Kidney Cancer | Testicular Germ Cell Tumor | Head and Neck Cancer | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Childhood Germ Cell Tumor

United States
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Evolution of Vestibular Function After Treatment of a Vestibular Schwannoma by Gamma-knife Radio-surgery

Vestibular Schwannoma | Acoustic Neuroma | Neurinoma, Acoustic
University Hospital Tuebingen

Not yet recruiting

Remote Ischemic Preconditioning in Vestibular Schwannoma Surgery (RIC-VS)

Vestibular Schwannoma

Germany

Clinical Trials on CAR-T Cell Immunotherapy

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in El Salvador

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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