Clinical Trials on CCNE1 Amplification
Total 67 results
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Southwest Oncology GroupNational Cancer Institute (NCI)CompletedCCND1 Gene Amplification | CCND2 Gene Amplification | CCND3 Gene Amplification | CDK4 Gene Amplification | Recurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7United States
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Merrimack PharmaceuticalsCompletedHER-2 Gene AmplificationUnited States
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Assiut UniversityNot yet recruitingGene Amplification
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Tianjin Medical University Second HospitalRecruiting
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Incyclix BioRecruitingBreast Cancer | Ovarian Cancer | Solid Tumor | Metastatic Cancer | Advanced Cancer | Breast Cancer Metastatic | Hormone Receptor Positive Tumor | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | CCNE1 AmplificationUnited States, Australia
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Jin-Hee AhnAsan Medical CenterUnknownHER-2 Gene Amplification | HER-2 Protein Overexpression
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Novartis PharmaceuticalsCompletedAdvanced Solid Tumors With Alterations of FGFR1, 2 and or 3 | Squamous Lung Cancer With FGFR1 Amplification | Bladder Cancer With FGFR3 Mutation or Fusion | Advanced Solid Tumors With FGFR1 Amplication | Advanced Solid Tumors With FGFR2 Amplication | Advanced Solid Tumors With FGFR3 MutationFrance, Spain, Taiwan, Germany, Netherlands, Singapore, United States, Australia, Korea, Republic of, Thailand, Israel, Italy, Turkey, Austria
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Kidney Cancer Research BureauRecruitingMetastatic Gastric Cancer | FGFR2 Amplification | PD-L1 Gene AmplificationUnited States
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Arog Pharmaceuticals, Inc.AvailableFLT3-ITD Mutation | FLT3/TKD Mutation | PDGFR-Alpha D842V | PDGFRA Gene AmplificationItaly
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Taiho Oncology, Inc.Active, not recruitingMetastatic Breast Cancer | FGFR2 Amplification | FGFR 1 High AmplificationItaly, United States, France, United Kingdom, Spain, Portugal, Canada
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Inonu UniversityAnadolu UniversityActive, not recruitingInfections | Immune Response | Liver Transplant; Complications | Gene AmplificationTurkey
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Tianjin Medical University Second HospitalJiangsu HengRui Medicine Co., Ltd.UnknownSolid Tumor | HER-2 Gene Amplification | HER2 Gene Mutation | HER-2 Protein OverexpressionChina
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingAdvanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | KRAS Gene Mutation | Metastatic Malignant Solid Neoplasm | EGFR Gene Mutation | ERBB2 Gene Amplification | ERBB2 Gene Mutation | EGFR Gene Amplification | ERBB3 Gene Mutation | ERBB4 Gene MutationUnited States
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Chungbuk National University HospitalMerck KGaA, Darmstadt, GermanyRecruitingSolid Tumor | MET Amplification | MET Exon 14 Skipping MutationKorea, Republic of
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Southwest Oncology GroupNational Cancer Institute (NCI)CompletedRecurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7 | FGFR1 Gene Amplification | FGFR2 Gene Amplification | FGFR2 Gene Mutation | FGFR3 Gene Mutation | FGFR1 Gene Mutation | FGFR3 Gene AmplificationUnited States, Canada
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Cancer Institute and Hospital, Chinese Academy...RecruitingCarcinoma, Transitional Cell | HER-2 Gene AmplificationChina
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Symphogen A/SCompletedNSCLC | Non Small Cell Lung Cancer | Oncology | MET Gene Mutation | MET Gene AmplificationUnited States, Korea, Republic of, Denmark, Hong Kong, Taiwan, Spain
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Orum Therapeutics USA, Inc.RecruitingHER2-positive Breast Cancer | HER-2 Gene Amplification | HER2 Gene Mutation | HER-2 Protein OverexpressionUnited States
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Blueprint Medicines CorporationRecruitingGastric Cancer | Ovarian Cancer | Carcinosarcoma | Advanced Solid Tumors | Endometrial Cancer | Esophageal Adenocarcinoma | HER2-negative Breast Cancer | CCNE1 Amplification | HR+ Breast CancerUnited States, Italy, United Kingdom
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University Hospital, BrestUnknownBreast Neoplasms | HER-2 Gene AmplificationFrance
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Sameek RoychowdhuryNational Cancer Institute (NCI)WithdrawnLocally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | ALK Gene Mutation | Metastatic Malignant Neoplasm in the Brain | Advanced Malignant Neoplasm | ALK Fusion Protein Expression | Metastatic Malignant Neoplasm in the Central Nervous System | ROS1 Gene Mutation | ALK Gene... and other conditionsUnited States
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Tianjin Medical University Second HospitalRecruitingSolid Tumor | FGF Receptor Gene Mutation | FGF Amplification | FGF Receptor Gene Family Rearrangement | FGF Receptor Gene TranslocationChina
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Peking Union Medical College HospitalRecruitingLight Chain (AL) Amyloidosis | Venetoclax | CCND1 TranslocationChina
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Chania General Hospital "St. George"University of ThessalyNot yet recruitingDepression | Anxiety | Cognitive Function 1, Social | Satisfaction, Consumer | Amplification | Hearing Aid | Listening Effort
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University of Colorado, DenverSonova AGRecruitingHearing Loss | Speech Perception | Children With Hearing Differences | AmplificationUnited States
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)Active, not recruitingMetastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC v8 | Stage IIIC Colorectal Cancer AJCC v8 and other conditionsUnited States
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Emory UniversityNational Cancer Institute (NCI); Genentech, Inc.; National Institutes of Health...Active, not recruitingMantle Cell Lymphoma | CCND1 Positive | t(11;14) PositiveUnited States
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Relay Therapeutics, Inc.Active, not recruitingCholangiocarcinoma | Intrahepatic Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Amplification | FGFR2 Gene Fusion/Rearrangement | FGFR2 Gene Translocation | FGFR2 Gene Activation | Other Solid Tumors, AdultUnited States, France, Italy, United Kingdom, Korea, Republic of, Spain, Taiwan, Sweden, Germany, Netherlands, Singapore, Australia, Hong Kong
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Merrimack PharmaceuticalsTerminatedStomach Cancer | Gastroesophageal Junction Cancer | HER-2 Gene Amplification | Esophagus CancerUnited States
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Samsung Medical CenterCompletedGlioblastoma, Adult | EGFR AmplificationKorea, Republic of
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Assistance Publique - Hôpitaux de ParisUnknownStage IV Melanoma | Stage III Melanoma | Amplification | Malignant Skin Melanoma T0France
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University of ChicagoNovartisTerminatedHead and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Carcinoma | Human Papillomavirus Infection | Recurrent Oropharyngeal Squamous Cell Carcinoma | FGFR Gene Amplification | FGFR1 Gene Amplification | FGFR2 Gene Amplification | FGFR2 Gene Mutation | FGFR3 Gene Mutation | Recurrent Nasopharynx...United States
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Sun Yat-sen University307 Hospital of PLA; Fudan University; West China Hospital; Tongji Hospital; Second... and other collaboratorsCompletedStomach Neoplasms | ERBB2 Gene Amplification | Neoplasms MetastasisChina
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Changhoon YooCompletedCholangiocarcinoma | Biliary Tract Cancer | HER-2 Gene Amplification | HER-2 Protein OverexpressionKorea, Republic of
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Daping Hospital and the Research Institute of Surgery...CompletedNSCLC | Advanced Cancer | EGFR Gene Amplification | Stage IV NSCLC | Stage IIIB NSCLCChina
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Xiaohua ZhuRecruitingNSCLC Stage IV | PD-L1 Gene AmplificationChina
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Haihe Biopharma Co., Ltd.UnknownNegative T790M Mutation and Met AmplificationChina
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National Cancer Institute (NCI)Gynecologic Oncology GroupCompletedRecurrent Uterine Corpus Carcinoma | Endometrial Adenocarcinoma | Stage III Uterine Corpus Cancer AJCC v7 | Stage IV Uterine Corpus Cancer AJCC v7 | ERBB2 Gene AmplificationUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)WithdrawnMantle Cell Lymphoma | CCND1 Positive | CD20-Positive Neoplastic Cells Present
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Bursa Yüksek İhtisas Education and Research HospitalRecruitingPneumonia, Viral | COVID-19 Pneumonia | EGFR AmplificationTurkey
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H. Lee Moffitt Cancer Center and Research InstituteTerminatedBreast Cancer | Breast Cancer, Male | HER2-positive Breast Cancer | HER-2 Gene Amplification | Breast Cancer Female | HER2 Positive Breast Carcinoma | HER-2 Protein OverexpressionUnited States
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Jonsson Comprehensive Cancer CenterAstraZenecaActive, not recruitingGlioblastoma | Recurrent Glioblastoma | EGFR Gene Mutation | Supratentorial Glioblastoma | EGFR Gene Amplification | TP53 wt AlleleUnited States
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Ashwin SomasundaramEMD Serono; University of North Carolina, Chapel HillCompletedGastric Adenocarcinoma | Metastasis | Esophageal Adenocarcinoma | HER-2 Gene AmplificationUnited States
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Bellicum PharmaceuticalsSuspendedHER2-positive Breast Cancer | HER2-positive Gastric Cancer | Solid Tumor, Adult | HER-2 Gene Amplification | HER-2 Protein OverexpressionUnited States
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Guangdong Provincial People's HospitalShanghai Junshi Bioscience Co., Ltd.RecruitingNon-Small Cell Lung Cancer | BRAF V600 Mutation | MET Amplification | MET Exon 14 Skipping Mutation | RET Driver Mutation | Erb-B2 Receptor Tyrosine Kinase Exon 20 MutationChina
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Enliven TherapeuticsRecruitingColorectal Cancer | HER2-positive Breast Cancer | HER2-positive Gastric Cancer | HER2 Amplification | HER2 Positive Solid TumorsUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingRecurrent Mantle Cell Lymphoma | Mantle Cell Lymphoma | CCND1 Positive | CCND2 Positive | CCND3 Positive | CD20 Positive | Refractory Mantle Cell LymphomaUnited States
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Massachusetts General HospitalPfizer; Array BioPharmaRecruitingNSCLC | Lung Cancer | Relapsed Cancer | Resistant Cancer | MET Amplification | Anaplastic Lymphoma Kinase Gene Translocation | ROS1 RearrangementUnited States
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University Health Network, TorontoPfizerRecruitingNon-squamous Non-small-cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | ROS1 Gene Rearrangement | MET Activating Mutation | MET AmplificationCanada
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Morten Mau-SørensenOdense University Hospital; Aarhus University Hospital; Aalborg University HospitalRecruitingEsophageal Squamous Cell Carcinoma | HER-2 Gene Amplification | HER-2 Protein OverexpressionDenmark