Clinical Trials on CNS BRAIN

Total 33359 results

Guerbet

Completed

P03277 Dose Finding Study in Central Nervous System (CNS) Magnetic Resonance Imaging (MRI)

Blood Brain Barrier Defect | CNS Lesion

Korea, Republic of, United States, Czechia, Italy, Belgium, Poland, Hungary, Mexico
Guerbet

Completed

Efficacy and Safety of Gadopiclenol for Central Nervous System (CNS) Magnetic Resonance Imaging (MRI) (PICTURE)

Blood Brain Barrier Defect | CNS Lesion

United States, Spain, Korea, Republic of, Taiwan, France, Hungary, Belgium, Germany, Italy, Mexico, Poland
Varian, a Siemens Healthineers Company

Recruiting

HyperArc Registry Study

Brain Metastases | CNS Neoplasm | CNS Disorder, Intracranial

United States, Australia
Ministry of Health, Malaysia

Unknown

A Clinical Study on Albert Wong Frame-based Stereotactic Biopsy System for Brain (AWF)

Intracranial CNS Disorder

Malaysia
National Cancer Institute (NCI)

Withdrawn

Wee1 Kinase Inhibitor AZD1775 and Combination Chemotherapy in Treating Children, Adolescents and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Recurrent Childhood Acute Myeloid Leukemia | CNS 2a | CNS 2b | CNS 2c | CNS1
Sintetica SA
Sintesi Research Srl

Completed

Observational Study on 2-chloroprocaine Hydrochloride 1% (PASS)

Neurological Complication, in Particular TNS or CES

Belgium
Memorial Sloan Kettering Cancer Center

Completed

Rituximab, Methotrexate, Procarbazine and Vincristine Followed by High-dose Chemotherapy With Autologous Stem-cell Rescue in Newly-diagnosed Primary CNS Lymphoma (PCNSL)

Non-Hodgkin's Lymphoma | CNS Lymphoma | CNS Brain Cancer

United States
Memorial Sloan Kettering Cancer Center

Completed

Imaging Brain Tumors With FACBC and Methionine

Brain Cancer | CNS Cancer

United States
Memorial Sloan Kettering Cancer Center

Completed

Language Function in Patients With Brain Tumors

Brain Cancer | CNS Cancer

United States
St. Jude Children's Research Hospital
Eli Lilly and Company

Active, not recruiting

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors

Brain Cancer | Brain Tumor | Medulloblastoma | Brain Tumor, Recurrent | CNS Tumor | Medulloblastoma Recurrent | CNS Cancer | Medulloblastoma, Non-WNT/Non-SHH | Brain Tumor, Pediatric | CNS Neoplasm | Brain Tumor, Refractory | Medulloblastoma, Non-WNT/Non-SHH, Group 3 | Medulloblastoma, Non-WNT/Non-SHH, Group 4

United States
University of Pennsylvania
The Cleveland Clinic

Recruiting

Longitudinal Study for Central Nervous System Vasculitis

Vasculitis | CNS Vasculitis | Central Nervous System Vasculitis | CNSV

United States, Canada
Memorial Sloan Kettering Cancer Center
Massachusetts General Hospital; Northwestern University; University of Calgary; Schering-Ploug... and other collaborators

Completed

Intensive Chemotherapy and Autotransplantation for Patients With Newly Diagnosed Anaplastic Oligodendroglioma

CNS Cancer | CNS BRAIN

United States
Massachusetts General Hospital

Active, not recruiting

Prospective Assessment of Quality of Life (QOL) in Pediatric Patients Treated With Radiation Therapy for Brain Tumors and Non-central Nervous System (Non-CNS) Malignancies

Brain Tumors | Non-CNS Malignancies

United States
Memorial Sloan Kettering Cancer Center
Weill Medical College of Cornell University

Completed

Adjunctive Donepezil Therapy and Genetic Risk Factors of Cognitive Dysfunction in Brain Tumor Survivors

Cognitive Dysfunction | Brain Cancer | Brain Tumor | Cns Cancer

United States
Jules Bordet Institute
Bristol-Myers Squibb; La Fondation contre le cancer, Belgique; Les Amis de l'Institut... and other collaborators

Recruiting

A Brain Metastases Research Platform to Tackle the Challenge of CNS Metastases in Solid Tumours (BrainStorm)

CNS Metastases

Belgium, France, Luxembourg
University Health Network, Toronto

Completed

Cognitive Support Program for Patients With Brain Metastases

Metastases, CNS

Canada
University of California, San Francisco

Not yet recruiting

Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a Myelin Repair Therapy (ReINFORCE)

Demyelinating Diseases | Clinically Isolated Syndrome, CNS Demyelinating | Multiple Sclerosis Brain Lesion | Multiple Sclerosis Acute and Progressive | Demyelination; Corpus Callosum

United States
National Cancer Institute (NCI)

Terminated

A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research Purposes

PNET | Gliomas | Pineal Tumors | Ependymomas | PCNSL (Primary CNS Lymphoma)

United States
Eisai Inc.

Completed

2-Part Multiple Ascending Dose Study for Safety and Pharmacokinetics in Healthy and Elderly Subjects

CNS

United States
Copenhagen University Hospital at Herlev
Rigshospitalet, Denmark; Glostrup University Hospital, Copenhagen

Terminated

Electrochemotherapy as a Palliative Treatment for Brain Metastases

Brain Metastases | CNS Metastases

Denmark
University of New Mexico

Completed

A Phase I Trial Using Combination Irinotecan and Thalidomide for Recurrent CNS Tumors

Cancer | Brain and Nervous System

United States
The Methodist Hospital Research Institute

Withdrawn

Phase II Trial of Chemotherapy With Temodar With Topotecan for CNS Metastasis of Solid Tumors

Brain Metastases | Central Nervous System (CNS) Metastases

United States
Kessler Foundation

Completed

Remediation of Emotional Deficits in Multiple Sclerosis and Traumatic Brain Injury

Multiple Sclerosis | Traumatic Brain Injury

United States
Duke University
Novartis; National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Zoledronate in Preventing Osteoporosis in Patients With Primary Malignant Glioma

Osteoporosis | Brain Tumors | Central Nervous System(CNS)Malignancies

United States
Genmab
BioNTech SE

Recruiting

A Safety and Antitumor Activity Trial of Immunoradiotherapy Combinations as a Treatment Option for Subjects With Metastatic Solid Tumors

Non-CNS Tumor

France
Shirley Ryan AbilityLab
Northwestern University

Unknown

Physiology of Interregional Connectivity in the Human Brain

Stroke | Multiple Sclerosis | Healthy | Traumatic Brain Injury

United States
Kessler Foundation

Unknown

Validation of an Obstacle Course Used in Patients With Muscle Tightness

Stroke | Multiple Sclerosis | Traumatic Brain Injury | Spasticity | Healthy Controls

United States
AstraZeneca

Completed

Study to Evaluate the Abuse Potential of AZD7325 in Healthy Recreational Central Nervous System (CNS) Depressant Users

Recreational CNS Depressant Use

Canada
St. Jude Children's Research Hospital

Recruiting

Methionine PET/CT Studies In Patients With Cancer

Hodgkin Lymphoma | Osteosarcoma | Ewing Sarcoma | Ependymoma | Medulloblastoma | Non Hodgkin Lymphoma | Neuroblastoma | Craniopharyngioma | Rhabdomyosarcoma | Other | Brain Stem Glioma | Brain Tumors and/or Solid Tumors Including | High Grade CNS Tumors | Low Grade CNS Tumors

United States
Kessler Foundation
Instituto Vocacional Enrique Díaz de León A.C., Guadalajara, Mexico

Recruiting

Improving Learning in Hispanics With TBI or MS

TBI (Traumatic Brain Injury) or MS (Multiple Sclerosis)

United States, Spain
Ning Wang, MD., PhD.

Recruiting

A Registered Cohort Study of Inflammatory Demyelination Disease

Demyelinating Autoimmune Diseases, CNS

China
Nuffield Orthopaedic Centre NHS Trust
Oxford Brookes University

Completed

Motor Imagery Practice in Neurological Rehabilitation

Stroke | Multiple Sclerosis | Brain Injury

United Kingdom
Arbor Pharmaceuticals, Inc.

Active, not recruiting

Vigilant ObservatIon of GlIadeL WAfer ImplaNT Registry (VIGILANT)

CNS Tumor

United States
Columbia University
National Multiple Sclerosis Society; Exegi Pharma

Recruiting

Prebiotic vs Probiotic in Multiple Sclerosis (MS)

Multiple Sclerosis | Clinically Isolated Syndrome (CIS)

United States
MedtronicNeuro

Completed

Measuring Signatures in the Fluid Surrounding the Spinal Cord in Patients Who Have Problems With Intrathecal Drug Delivery

Multiple Sclerosis | Cerebral Palsy | Traumatic Brain Injury | Spinal Cord Injury

United States
Mayo Clinic

Recruiting

Cognitive Function After Treatment of Primary CNS Malignancy

CNS Malignancy

United States
Mayo Clinic

Enrolling by invitation

A Study of Metabolic Agents Following Brain Radiation

CNS Malignancy

United States
Fondazione Don Carlo Gnocchi Onlus
Lithuanian University of Health Sciences; Hospital Nacional de Parapléjicos... and other collaborators

Completed

PURO - PUlmonary Rehabilitation With O-RAGT Platform (PURO)

Stroke | Multiple Sclerosis | Spinal Cord Injury | Traumatic Brain Damage

Lithuania, Spain, Italy, Netherlands
Huashan Hospital
United Imaging Healthcare

Recruiting

Artificial Intelligence Neuropathologist

Neuropathology | CNS Tumor

China
University Medical Center Groningen

Recruiting

Improving Social Cognition and Social Behaviour in Various Brain Disorders (T-ScEmo4ALL)

Stroke | Multiple Sclerosis | Brain Tumor

Netherlands
Matthew J. Frigault, M.D.
Novartis

Active, not recruiting

Tisagenlecleucel In Primary CNS Lymphoma

Primary CNS Lymphoma | Refractory Primary CNS Lymphoma | Relapsed Primary CNS Lymphoma

United States
Rigshospitalet, Denmark

Recruiting

Whole Body Metabolism in Children Before and After Treatment of CNS Tumor

CNS Tumor, Childhood

Denmark
Reveal Pharmaceuticals Inc.
National Cancer Institute (NCI)

Recruiting

Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent

Central Nervous System (CNS) Lesions

United States
Nancy Lin, MD
Bayer; Brigham and Women's Hospital; Breast Cancer Research Foundation

Terminated

ZK219477 (Sagopilone) in Patients With Breast Cancer and Brain Metastases

Breast Cancer | CNS Disease

United States
Guerbet
Bracco Imaging S.p.A.

Recruiting

Evaluation of Gadopiclenol for Magnetic Resonance Imaging (MRI) in Japanese Adults and Children

CNS Lesion | Lesion in Body Region

Japan
Charite University, Berlin, Germany

Recruiting

Pregnancy Cohort in Multiple Sclerosis (MS)

Multiple Sclerosis (MS) | Clinically Isolated Syndrome (CIS)

Germany
University of Wisconsin, Madison

Terminated

Pilot Study of 18F-FLT PET

Head and Neck Cancer | Esophageal Cancer | Lung Cancer | Prostate Cancer | CNS Brain Metastasis

United States
University of Wisconsin, Madison

Terminated

Pilot Study of (61)CuATSM-PET Imaging in Cancer Patients

Head and Neck Cancer | Esophageal Cancer | Lung Cancer | Prostate Cancer | CNS Brain Metastases

United States
University Hospital Heidelberg
German Cancer Research Center

Recruiting

INFORM2 Study Uses Nivolumab and Entinostat in Children and Adolescents With High-risk Refractory Malignancies (INFORM2 NivEnt)

Solid Tumor | CNS Tumor

France, Germany, Australia, Austria, Sweden, Netherlands, Switzerland
Tata Memorial Centre
Bhabha Atomic Research Centre (BARC)

Active, not recruiting

Artificial Intelligence in CNS Radiation Oncology (AI-RAD)

CNS Tumor

India

Clinical Trials on CNS BRAIN

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uzbekistan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations