Clinical Trials on Calcific Aortic Stenosis

Total 5097 results

Assiut University
Manchester University NHS Foundation Trust

Unknown

Early Outcomes of Concomitant Transcatheter Aortic Valve Implantation and Off-pump Coronary Artery Bypass Grafting in Management of Severe Symptomatic Aortic Stenosis and Coronary Artery Disease

Coronary Artery Disease | Aortic Valve Disease

Egypt
Tomsk National Research Medical Center of the Russian...

Completed

Mitral Valve in Hypertrophic Cardiomyopathy

Hypertrophic Obstructive Cardiomyopathy

Russian Federation
University Hospital, Strasbourg, France

Not yet recruiting

Expression of Sodium-glucose Co-transporter 2 in Human Heart (SGLT2-MICRA)

Aortic Valve Stenosis

France
University of Virginia

Recruiting

Platelet Adhesion in the Pathobiology of Aortic Stenosis

Aortic Valve Stenosis

United States
University Hospital, Lille
Ministry of Health, France

Recruiting

Balloon-Expandable Versus Self-expanding Transcatheter Heart Valve for Treatment of Symptomatic Native Aortic Valve Stenosis (BEST) (BEST)

Aortic Valve Stenosis

France
Radboud University Medical Center

Recruiting

Myeloid Cells in Aortic Valve Stenosis (MIRACLE)

Aortic Valve Stenosis | Aortic Valve Disease

Netherlands
Meril Life Sciences Pvt. Ltd.

Recruiting

Myval Global Study of Myval™ THV Series Implanted in Patients With Native Severe Aortic Valve Stenosis.

Aortic Valve Stenosis

Slovenia, Spain, Turkey, Italy, Netherlands, Estonia, Poland
University Hospital, Rouen
University Hospital, Caen

Recruiting

Measurement of Myocardial Stiffness Using Elastometry in Patients With Aortic Stenosis (ELASTOP-AS)

Aortic Valve Stenosis

France
Biotronik AG
Medstar Health Research Institute

Completed

BIOVALVE - I / II Clincial Investigation (BIOVALVE)

Aortic Valve Stenosis | Heart Valve Diseases

Belgium, Germany, Switzerland, Netherlands
Catharina Ziekenhuis Eindhoven

Active, not recruiting

Stress Aortic Valve Index for Assessing Risk in Aortic Valve Stenosis Patients (SAVI-AoS)

Aortic Valve Stenosis

Denmark, Netherlands, United States
Cardiawave SA

Completed

Valvosoft First-In-Man Study in Severe Symptomatic Aortic Stenosis

Aortic Valve Stenosis

France, Netherlands
Cardiawave SA

Active, not recruiting

Valvosoft First-In-Human Study in Severe Symptomatic Aortic Stenosis

Aortic Valve Stenosis

Serbia
Aarhus University Hospital Skejby

Completed

Pressure Gradient vs. Flow Relationships in Patients With Symptomatic Valvular Aortic Stenosis (PREFLOW)

Aortic Valve Stenosis

Denmark
Edwards Lifesciences

Active, not recruiting

ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis

Aortic Valve Stenosis

United States
University Hospital Inselspital, Berne

Completed

Morbidity and Mortality Due to Deferral of Aortic Valve Replacement in Patients With Severe Aortic Stenosis (AS DEFER)

Aortic Valve Stenosis

Switzerland
Heinrich-Heine University, Duesseldorf

Completed

Evaluation of BAV in Different Hemodynamic Entities of Severe AS (BAV)

Aortic Valve Stenosis

Germany
Henry Ford Health System

Withdrawn

CPX in Paradoxical Low Flow Aortic Stenosis

Aortic Valve Stenosis

United States
University Hospital Inselspital, Berne

Completed

Volume Challenge Added to DSE in the Diagnosis of Severe LFLGAS (FLOW-AS)

Aortic Valve Stenosis

Switzerland
German Heart Institute
Charite University, Berlin, Germany

Unknown

Validation of a Novel, Non-Dimensional Approach for Estimation of Pressure Gradients in Aortic Stenosis (AVD-PowerLaw)

Aortic Valve Stenosis

Germany
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Completed

Quality of Care in AS IMPULSE Study (IMPULSE)

Aortic Valve Stenosis

United Kingdom, Germany, Switzerland, Austria, France, Italy, Netherlands, Czechia, Spain
Rennes University Hospital

Completed

Low Flow Low Gradient Aortic Stenosis Relevance of the (re)Search for a Contractile Reserve (LOWAS)

Aortic Valve Stenosis

France
AORTICA Group

Terminated

Randomized Study to Evaluate the Efficacy of Fluvastatin on Inflammatory Markers in Patients With Aortic Stenosis.

Aortic Valve Stenosis

Spain
The Cleveland Clinic
Pfizer

Terminated

The Effect of Lipitor on Aortic Stenosis

Aortic Valve Stenosis

United States
Seung-Jung Park
CardioVascular Research Foundation, Korea

Withdrawn

TRANscatheter or SurgIcal Aortic Valve ReplacemenT in All-Comers With Severe Aortic Valve Stenosis (TRANSIT)

Aortic Valve Stenosis

Korea, Republic of
Direct Flow Medical, Inc.

Unknown

A Registry to Evaluate the Direct Flow Medical Transcatheter Aortic Valve System (DISCOVER)

Aortic Valve Stenosis

Germany, Italy
University of North Carolina, Chapel Hill
Cook Group Incorporated; UNC Hospitals

Enrolling by invitation

Evaluation of Visceral Function Following Endovascular Aortic Aneurysm Repair Using Branched Stent- Grafts

Aortic Aneurysm, Abdominal | Aortic Arch Aneurysm | Ascending Aorta Aneurysm

United States
University of California, San Francisco

Completed

Fetal Intervention for Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome

Aortic Stenosis | Hypoplastic Left Heart Syndrome

United States
SuZhou Sinus Medical Technologies Co.,Ltd

Recruiting

Septal Ablation for Obstructive HCM

Hypertrophic Obstructive Cardiomyopathy (HOCM)

China
Baylor Research Institute

Recruiting

Prospective Evaluation of Neurocognition in Patients Undergoing Transcatheter Aortic Valve Replacement (Neurcog TAVR)

Aortic Stenosis | Mild Cognitive Impairment

United States
Bristol-Myers Squibb

Active, not recruiting

A Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy (VALOR-HCM)

HOCM, Hypertrophic Obstructive Cardiomyopathy

United States
China National Center for Cardiovascular Diseases

Completed

Association Between Microvascular Resistance and Outcomes in Patients With Obstructive Hypertrophic Cardiomyopathy

Hypertrophic Obstructive Cardiomyopathy | Microvascular Dysfunction | Microcirculation Resistance

China
Mayo Clinic

Withdrawn

Comparison of Squat-to-Stand Maneuver With Amyl Nitrite, Valsalva, and Exercise Stress Echocardiography in Inducing Latent Left Ventricular Outflow Obstruction in Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy | Cardiomyopathy, Hypertrophic | Hypertrophic Obstructive Cardiomyopathy
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
Cytokinetics

Completed

Safety, Tolerability and Pharmacokinetics Study of CK-3773274

Healthy Adult Subjects | Obstructive Hypertrophic Cardiomyopathy

China
Duke University
Gilead Sciences

Completed

Ranolazine for the Treatment of Chest Pain in HCM Patients (RHYME)

Hypertrophic Cardiomyopathy

United States
Meshalkin Research Institute of Pathology of Circulation

Completed

Surgical Treatment of Hypertrophic Obstructive Cardiomyopathy With Severe Mitral Insufficiency.

Hypertrophic Obstructive Cardiomyopathy

Russian Federation
Shaare Zedek Medical Center
Medtronic

Unknown

CRyo-Ablation to Treat Patients With HOCM. (CRASH)

HOCM, Hypertrophic Obstructive Cardiomyopathy
Hospital Universitari Son Dureta
Laboratorios BIOMED SA

Unknown

Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications (CALCIFICA)

Aortic Stenosis | Heart Valve Disease

Spain
Abbott Medical Devices

Completed

Trifecta™ Long Term Follow-Up (LTFU) Study

Aortic Valve Stenosis | Aortic Valve Insufficiency | Aortic Valve Incompetence | Aortic Valve Regurgitation

United States, Canada
Abbott Medical Devices

Completed

Aortic Valve Replacement With Trifecta(TM)

Aortic Valve Stenosis | Aortic Valve Insufficiency | Regurgitation, Aortic Valve | Aortic Valve Incompetence

United States
Abbott Medical Devices

Completed

An Observational, Prospective Evaluation of the Trifecta™ Valve

Aortic Valve Stenosis | Aortic Valve Insufficiency | Regurgitation, Aortic Valve | Aortic Valve Incompetence

Germany, Netherlands, France
Amsterdam UMC, location VUmc

Recruiting

Assessment of Cardiac Function, Microvascular Function and Cardiac Perfusion in Different Disease Stages of Hypertrophic Cardiomyopathy (FUSION-HCM)

Hypertrophic Cardiomyopathy | Hypertrophic Cardiomyopathy, Obstructive

Netherlands
Oslo University Hospital
Oslo Metropolitan University

Not yet recruiting

10-year Follow-up After Aortic Valve Replacement Surgery (AVR-10year)

Quality of Life | Aortic Stenosis | Anxiety | Depressive Symptoms
Guangdong Provincial People's Hospital

Recruiting

Observational Study for Patients With Hypertrophic Cardiomyopathy

HCM - Hypertrophic Cardiomyopathy

China
Imbria Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, and Efficacy of IMB-1018972 in Patients With Non-obstructive Hypertrophic Cardiomyopathy Trial (IMPROVE-HCM)

Non-obstructive Hypertrophic Cardiomyopathy

United States, United Kingdom
LianBio LLC

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Mavacamten in Chinese Adults With Symptomatic Obstructive HCM

Obstructive Hypertrophic Cardiomyopathy

China
Hangzhou Valgen Medtech Co., Ltd

Active, not recruiting

Feasibility Study of the DragonFire for Hypertrophic Obstructive Cardiomyopathy

Obstructive Hypertrophic Cardiomyopathy

China
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Patients' Long-Term Survival of Obstructive Hypertrophic Cardiomyopathy (HCM)

Cardiomyopathy | Obstructive Hypertrophic Cardiomyopathy

United States
Steen Hvitfeldt Poulsen

Completed

The Effect of Metoprolol in Patients With Hypertrophic Obstructive Cardiomyopathy. (TEMPO)

Hypertrophic Cardiomyopathy

Denmark
Abbott Medical Devices

Completed

Triple Chamber Pacing in Hypertrophic Obstructive Cardiomyopathy (HOCM) Patients - TRICHAMPION STUDY (TRICHAMPION)

Hypertrophic Cardiomyopathy With Obstruction

Spain
University of Catania

Completed

Reobtain Coronary Ostia Cannulation Beyond Transcatheter Aortic Valve Stent (RE-ACCESS) (RE-ACCESS)

Coronary Artery Disease | Aortic Stenosis

Italy

Clinical Trials on Calcific Aortic Stenosis

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