Clinical Trials on Calcific Aortic Stenosis

Total 5062 results

Abbott Medical Devices

Completed

Trifecta™ Long Term Follow-Up (LTFU) Study

Aortic Valve Stenosis | Aortic Valve Insufficiency | Aortic Valve Incompetence | Aortic Valve Regurgitation

United States, Canada
Abbott Medical Devices

Completed

Aortic Valve Replacement With Trifecta(TM)

Aortic Valve Stenosis | Aortic Valve Insufficiency | Regurgitation, Aortic Valve | Aortic Valve Incompetence

United States
Abbott Medical Devices

Completed

An Observational, Prospective Evaluation of the Trifecta™ Valve

Aortic Valve Stenosis | Aortic Valve Insufficiency | Regurgitation, Aortic Valve | Aortic Valve Incompetence

Germany, Netherlands, France
Friedrich-Alexander-Universität Erlangen-Nürnberg
University of Erlangen-Nürnberg Medical School

Recruiting

Detection of Aortic Stenosis With Smartphone Auscultation Using Machine Learning (HEARTBEAT-Pilot)

Aortic Valve Stenosis

Germany
Tempus AI
Medtronic

Not yet recruiting

Addressing Undertreatment and Health Equity in Aortic Stenosis Using an Integrated EHR Platform (ALERT)

Aortic Valve Stenosis
Venus MedTech (HangZhou) Inc.

Not yet recruiting

Venus-Vitae Pivotal Study Smart-Align Study

Aortic Valve Stenosis
McGill University Health Centre/Research Institute...

Recruiting

Translational-Omics in Aortic Stenosis (TOmAS) Biobank

Cardiovascular Diseases | Aortic Valve Stenosis

Canada
Valve Medical

Recruiting

FIH Study of the GEMINUS TAVI System in Patients With Severe Symptomatic Aortic Stenosis

Aortic Valve Stenosis

Israel
Shanghai NewMed Medical Co., Ltd.
West China Hospital; The General Hospital of Northern Theater Command

Recruiting

Prizvalve Pro™ Transcatheter Aortic Valve Replacement Study

Aortic Valve Stenosis

China
Duk-Woo Park, MD
CardioVascular Research Foundation, Korea; Daewoong Pharmaceutical Co. LTD.

Not yet recruiting

ENAVOgliflozin Outcome Trial in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement (ENAVO-TAVR)

Aortic Valve Stenosis

Korea, Republic of
Jessa Hospital

Recruiting

Outcome, Recuperation and Hemodynamics in Aortic Stenosis (PROCARE-AS)

Aortic Valve Stenosis

Belgium
Chengdu Silara Meditech Inc.

Recruiting

To Evaluate Safety and Effectiveness of Transcatheter Aortic Valve System in Patients With Severe Aortic Stenosis

Aortic Valve Stenosis

China
Meril Life Sciences Pvt. Ltd.

Recruiting

LANDMARK Trial: a Randomised Controlled Trial of Myval THV (LANDMARK)

Aortic Valve Stenosis

Sweden, Hungary, France, Belarus, Croatia, Germany, Netherlands, New Zealand, Poland, Portugal, Slovakia, Slovenia, Spain, Italy, Brazil, Estonia, Greece
Laval University
University Hospital, Brest

Recruiting

Multicenter Prospective Study of Low-Flow Low-Gradient Aortic Stenosis (TOPAS Study)

Aortic Valve Stenosis

United States, France, Austria, Belgium, Canada, Germany
IHF GmbH - Institut für Herzinfarktforschung
Yale University; Boston Scientific Group

Active, not recruiting

accuRate Evaluation of Benefit With Optimal Medical Treatment With or Without Transcatheter Valve Repair of PARADOXical Low Flow Low Gradient Aortic Stenosis (REBOOT-PARADOX)

Aortic Valve Stenosis

Germany
Shanghai NewMed Medical Co., Ltd.

Active, not recruiting

PrizValve® Transcatheter Aortic Valve Replacement Study

Aortic Valve Stenosis

China
Optimapharm
Edwards Lifesciences

Active, not recruiting

RHEIA (Randomized researcH in womEn All Comers With Aortic Stenosis) (RHEIA)

Aortic Valve Stenosis | Heart Valve Diseases

United Kingdom, Italy, Germany, France, Austria, Switzerland, Finland, Czechia, Belgium, Netherlands, Cyprus, Ireland
Massachusetts General Hospital
University of Colorado, Denver

Completed

Impact of a Patient Decision Aid for Treatment of Aortic Stenosis

Aortic Valve Stenosis

United States
Shanghai MicroPort CardioFlow Medtech Co., Ltd.

Unknown

VitaFlow™ Transcatheter Aortic Valve System Pre-market Trial

Aortic Valve Stenosis

China
Bassett Healthcare
Baylor University

Completed

Podocan and Wnt Pathway in Left Ventricular Remodeling of Aortic Stenosis

Aortic Valve Stenosis

United States
Irmandade Santa Casa de Misericórdia de Porto Alegre
Federal University of Health Science of Porto Alegre

Unknown

Cardiovascular Rehabilitation in Patients With Severe Aortic Stenosis Submitted to Valvar Correction (CARE-AS-MOTION)

Aortic Valve Stenosis

Brazil
Turku University Hospital
Helsinki University Central Hospital; Oulu University Hospital; Kuopio University... and other collaborators

Completed

Finnish Registry of Transcatheter and Surgical Aortic Valve Replacement for Aortic Valve Stenosis: FinnValve Registry (FinnValve)

Aortic Valve Stenosis

Finland
London North West Healthcare NHS Trust

Completed

Clinical Value of Stress Echocardiography in Moderate Aortic Stenosis

Aortic Valve Stenosis

United Kingdom
Medical University of South Carolina
General Electric

Completed

Aortic Stenosis Pre-Transcatheter Aortic Valve Replacement (TAVR) Procedure CT Scan

Aortic Valve Stenosis

United States
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Unknown

Genetic of Aortic Valve Stenosis - Clinical and Therapeutic Implications (GENERAC)

Aortic Valve Stenosis

France
Imperial College London

Unknown

Determination of the Acute Effects of Aortic Stenosis on Coronary Artery Haemodynamics

Aortic Valve Stenosis

United Kingdom
Jordan D. Miller, Ph.D.
National Center for Research Resources (NCRR); National Center for Advancing... and other collaborators

Completed

Safety of Ataciguat in Patients With Moderate Calcific Aortic Valve Stenosis

Aortic Valve Stenosis

United States
Second Affiliated Hospital, School of Medicine,...

Unknown

Safety and Efficacy of Lotus Valve For TAVI In Patients With Severe Aortic Stenosis In Chinese Population (LOTUS-CHINA)

Aortic Valve Stenosis

China
University of Leipzig
Novartis

Unknown

Statin Therapy in Asymptomatic Aortic Stenosis

Aortic Valve Stenosis

Germany
University of Helsinki
AstraZeneca

Unknown

The Potential of Candesartan to Retard the Progression of Aortic Stenosis (ROCK-AS)

Aortic Valve Stenosis

Finland
National and Kapodistrian University of Athens

Recruiting

SLOW-Slower Progress of caLcificatiOn With Vitamin K2

Aortic Valve Stenosis | Mitral Valve Stenosis | Aortic Valve Calcification | Mitral Annular Calcification | Mitral Valve Calcification

Greece
C. R. Bard

Completed

Progel Vascular Sealant

Aortic Valve Stenosis | Aortic Valve Disorder | Aneurysm of Ascending Aorta | Bicuspid Valve Disorder

United States
Assistance Publique - Hôpitaux de Paris
Action Research Group

Not yet recruiting

Antagonization of Heparin With Protamine Sulfate After TAVI (ATLANTIS-Prota)

Aortic Valve Stenosis | Heart Valve Diseases
Shanghai MicroPort CardioFlow Medtech Co., Ltd.

Recruiting

VitaFlow™ Transcatheter Aortic Valve System Post-market Study-The LAUNCH Study

Aortic Valve Stenosis

China
Edwards Lifesciences

Active, not recruiting

The SAPIEN 3 Ultra System in Intermediate Risk Patients With Symptomatic, Severe Aortic Stenosis

Aortic Valve Stenosis

Canada, United Kingdom
Rennes University Hospital

Terminated

Randomized Study for the Optimal Treatment of Symptomatic Patients With Low Gradient Severe Aortic Valve Stenosis and Preserved Left Ventricular Ejection Fraction (ROTAS)

Aortic Valve Stenosis

France, Belgium
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Completed

Registry to Evaluate the Impact of a Valve Coordinator on Aortic Stenosis / TAVI Outcome - (German Pilot) (Coordinate)

Aortic Valve Stenosis

Germany
Nicolaus Copernicus University

Completed

Aortic Valve replAcement in eLective Patients From aOrtic Valve multiceNter Registry (AVALON)

Aortic Valve Stenosis
University of Oxford
British Heart Foundation

Active, not recruiting

Oxford - Fibrates in Aortic Stenosis (OxFAST)

Aortic Valve Stenosis

United Kingdom
Edwards Lifesciences

Completed

PREVAIL-20J - Transfemoral Placement of 20mm Aortic Balloon Expandable Transcatheter Valve Trial (PREVAIL-20J)

Aortic Valve Stenosis

Japan
Edwards Lifesciences

Completed

PREVAIL-J - Transfemoral & Transapical Placement of Aortic Balloon Expandable Transcatheter Valves Trial (Japan)

Aortic Valve Stenosis

Japan
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Completed

Study to Improve Outcomes in Aortic Stenosis

Aortic Valve Stenosis

France, Germany
Medtronic Cardiovascular

Completed

Clinical Evaluation of MDT-2111 in Subjects With Small Aortic Annuli and Symptomatic Severe Aortic Stenosis

Aortic Valve Stenosis

Japan
National Heart, Lung, and Blood Institute (NHLBI)
Medstar Washington Hospital Center

Withdrawn

Use of Cardiac-MRI to Predict Results for People With Severe Aortic Stenosis

Aortic Valve Stenosis
Medtronic Cardiovascular

Completed

Clinical Evaluation of MDT-2111 in Subjects With Symptomatic Severe Aortic Stenosis

Aortic Valve Stenosis

Japan
Assiut University

Unknown

Outcomes of Transcatheter Aortic Valve Implantation in Management of Severe Symptomatic Aortic Stenosis (TAVI)

Aortic Valve Stenosis
Maastricht University Medical Center

Completed

Biological Variation of Cardiac Biomarkers in Aortic Valve Stenosis

Aortic Valve Stenosis

Netherlands
Baylor Research Institute

Completed

Improving Echo Measurements in the Diagnosis of Aortic Stenosis

Aortic Valve Stenosis

United States
Aarhus University Hospital Skejby
Odense University Hospital; Danish Heart Foundation

Terminated

Transapical Transcatheter Treatment Versus Conventional Surgery in Patients With Native Aortic Valve Stenosis

Aortic Valve Stenosis

Denmark
Seoul National University Hospital

Unknown

PCSK9 Inhibitors in the Progression of Aortic Stenosis

Aortic Valve Stenosis

Korea, Republic of

Clinical Trials on Calcific Aortic Stenosis

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