Clinical Trials on Cancer Disease Progression

Total 385410 results

Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
National Research Council

Recruiting

Using Tissue-based Spatial Data to Understand How Obesity-related Tumor Metabolites Fuel Prostate Cancer Progression (OBESITA'&PCa)

Obesity | Prostate Cancer | Prostate Adenocarcinoma | Prostate Neoplasm | Prostatic Neoplasm

Italy
Amsterdam UMC, location VUmc

Recruiting

Prior CABG Patients Evaluated for Saphenous VeIn grAft DysfUnction and Progression of Coronary arTery Disease (VIADUCT)

Graft Failure | Coronary Artery Disease Progression | Recurrent Angina After Coronary Artery Bypass Graft

Netherlands
Bangkok Metropolitan Administration Medical College...
Science research and innovation

Completed

Effect of Low Salt and Ckd Progression

Proteinuria | Blood Pressure | CKD Progression

Thailand
Jagiellonian University

Recruiting

Immunotherapy With Dinutuximab Beta in Combination With Chemotherapy for the Treatment of Patients With Primary Neuroblastoma Refractory to Standard Therapy and With Relapsed or Progressive Disease (ChIm-NB-PL)

High-Risk Neuroblastoma

Poland
The University of Hong Kong
Chinese University of Hong Kong

Completed

Progression From Impaired Fasting Glucose to Diabetes Mellitus Among Chinese

Progression From Impaired Fasting Glucose to Diabetes Mellitus

Hong Kong
University of Nottingham

Recruiting

Neuromelanin MRI: A Progression Marker in Early PD (InsIghtPD)

Parkinson Disease | Progression, Disease

United Kingdom
European Organisation for Research and Treatment...

Recruiting

Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study (LEGATO)

First Progression of Glioblastoma

Netherlands, Austria, Germany
Genentech, Inc.

Completed

Corrected QT Interval Effects of Trastuzumab Emtansine (T-DM1) in Patients With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Locally Advanced or Metastatic Breast Cancer and the Safety and Tolerability of Combined T-DM1 and Pertuzumab in Patients With Early Disease Progression

Metastatic Breast Cancer
Chulalongkorn University

Recruiting

Association Between Renal Reserve Function and Progression of Renal Function to Predict CKD Risk in Thai Elderly

Renal Function Abnormal | Elder

Thailand
Thoraxklinik-Heidelberg gGmbH
AstraZeneca

Completed

Real-world Analysis of Workup at Disease Progression and Implementation of Osimertinib for EGFR+ NSCLC

EGFR Positive Non-small Cell Lung Cancer

Germany
Weill Medical College of Cornell University
Oncolys BioPharma Inc

Terminated

Phase 2 Study of OBP-301 (Telomelysin™) in Combination With Pembrolizumab and SBRT in Patients With HNSCC With Inoperable, Recurrent or Progressive Disease

Head and Neck Squamous Cell Carcinoma With Inoperable Recurrent or Progressive Disease

United States
Northwestern University
National Cancer Institute (NCI); Vasgene Therapeutics, Inc

Active, not recruiting

sEphB4-HSA in Treating Patients With Metastatic Castration-Resistant Prostate Cancer

Progressive Disease | Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | PSA Progression | Metastatic Prostate Adenocarcinoma | Castration Levels of Testosterone | Prostate Carcinoma Metastatic in the Bone | Castration-Resistant Prostate Carcinoma Refractory to Second-Generation... and other conditions

United States
Mei Gao

Not yet recruiting

Factors Related to the Progression of Non-target Coronary Lesions

Coronary Stenosis
Columbia University
National Eye Institute (NEI)

Completed

Macular Damage in Early Glaucoma and Progression

Glaucoma

United States
Michael Choi
Pharmacyclics LLC.

Withdrawn

Obinutuzumab With High-dose Ibrutinib for the Treatment of Patients With Chronic Lymphocytic Leukemia With Progressive Disease on Single Agent Ibrutinib.

Chronic Lymphocytic Leukemia
Dendreon

Completed

Immunotherapy For Men With Objective Disease Progression On Protocol D9902 Part B (NCT00065442)

Metastatic Androgen Independent Prostate Cancer

United States, Canada
Sun Yat-sen University

Completed

Routine Therapy Plus Moxifloxacin in Advanced Breast Cancer

Advanced Breast Cancer | Antibiotic | Stable Disease With a Trend of Progression

China
Duke University
United States Department of Defense; Prostate Cancer Foundation; Janssen Diagnostics...

Completed

Isolation of Circulating Tumor Cells Using a Novel EMT-Based Capture Method (CTC-EMT)

Metastatic Progressive Castration-resistant Prostate Cancer | Metastatic Progressive Breast Cancer

United States
Tulane University School of Medicine
Sanofi; University of Washington; Preventice; Marrek, INC; Mckesson

Terminated

Effect of Dronedarone on Atrial Fibrosis Progression and Atrial Fibrillation Recurrence (EDORA)

Atrial Fibrillation | Atrial Fibrillation Recurrent

United States
Centro Nacional de Investigaciones Oncologicas...
Fundacion CRIS de Investigación para Vencer el Cáncer

Completed

Abrogation of Chronic Monoclonal Antibody Treatment-induced T-cell Exhaustion With DURVALUMAB in Advanced HER-2 Negative Breast Cancer

Metastatic Breast Cancer | Bevacizumab-alone Maintenance Treatment Progression

Spain
Radboud University Medical Center
Stichting Bevordering Tandheelkundige Kennis of the Nederlands Tijdschrift...

Completed

7 Year Follow up Analysis on the Speed of Progression of Tooth Wear Using 3D Subtraction

Reflux Acid | Bruxism | Tooth Wear

Netherlands
Poitiers University Hospital

Recruiting

New Imaging Biomarkers Predictive of MA Progression (MR7T-PRADA)

Alzheimer Disease | Magnetic Resonance Spectroscopy | Ultra High Field 7T | Progression of Disease | MR Biomarkers

France
Centre Hospitalier Universitaire de Pointe-a-Pitre
Institut National de la Santé Et de la Recherche Médicale, France

Recruiting

Clinical, Genetic and Environmental Determinants of Prostate Cancer Progression. (KP-CARAIBES)

Adenocarcinoma | Neoplasm Metastasis | Prostatic Neoplasm | Neoplasm Recurrence

France, Guadeloupe
University College London Hospitals

Unknown

FOcal RECurrent Assessment and Salvage Treatment (FORECAST)

Progression of Prostate Cancer

United Kingdom
Millennium Pharmaceuticals, Inc.

Completed

A Study of PS-341 Given to Patients With Multiple Myeloma Who Experienced Progressive Disease After Receiving Dexamethasone in M34101-039

Multiple Myeloma

United States, United Kingdom, Canada, Israel, France, Austria, Belgium, Germany, Ireland, Italy, Netherlands, Spain, Sweden
European Georges Pompidou Hospital
APHP

Recruiting

Pronostic and Predictive Value of EMT in Localized Lung Cancer (TWISTlung)

Progression | Surgery | NSCLC, Stage I, II, IIIA, IIIB | Epithelial Mesenchymal Transition

France
Institut du Cancer de Montpellier - Val d'Aurelle

Recruiting

Assessment of Retreatment With Lutathera® in Patients With New Progression of Intestinal Well-differenciated NET (ReLUTH)

Progressive Disease | Neuroendocrine Tumors | Intestinal Well Differentiated Endocrine Tumor

France
First Affiliated Hospital of Zhejiang University
Zhejiang Cancer Hospital; Second Affiliated Hospital, School of Medicine, Zhejiang... and other collaborators

Recruiting

Prospective Multicenter Clinical Study of Neoadjuvant Imatinib Mesylate for Gastrointestinal Stromal Tumors (ZJGIST-01)

Gastrointestinal Stromal Tumor | Progression-free Survival | Neoadjuvant

China
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); National Center...

Enrolling by invitation

Comparing Immune Activation and Latent HIV Reservoir Size Between People Living With HIV on Tenofovir-containing Versus NRTI-free ART

Inflammation | HIV | HIV-1-infection | HIV Disease Progression

United States
Weill Medical College of Cornell University
TG Therapeutics, Inc.

Terminated

Umbralisib Plus Ublituximab (U2) in Progressive CLL After Novel Therapy

Chronic Lymphocytic Leukemia | CLL/SLL | CLL Progression

United States
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

A Trial of Two Doses of 2',3'-Dideoxycytidine (ddC) in the Treatment of Children With Symptomatic HIV Infection Who Are Intolerant of AZT and/or Who Show Progressive Disease While on AZT

HIV Infections

United States, Puerto Rico
Genesis Pharma S.A.

Completed

A Retrospective Chart Review Study of the Outcomes of 2nd Line Therapy With LEn/Dex in Greek Patients With R/R Multiple MyEloma and the Treatment PatterNs Following Progressive Disease (LEGEND)

Relapsed/Refractory Multiple Myeloma

Greece
Spanish Oncology Genito-Urinary Group
Apices Soluciones S.L.; Janssen, LP

Completed

Abiraterone Acetate in Combination With Docetaxel After Disease Progression to Abiraterone Acetate in Metastatic Castration Resistant Prostate Cancer. (ABIDO)

Metastatic Prostate Cancer

Spain
Beijing Friendship Hospital

Unknown

Dynamic Changes and Risk Factors of Fibrosis and Steatosis Progression in Nonalcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver Disease

China
Aller, Thomas A., OD
Johnson & Johnson Vision Care, Inc.

Completed

Bifocal Soft Contact Lenses and Their Effect on Myopia Progression in Children and Adolescents.

Myopia | Esophoria | Fixation Disparity
Clinical Hospital Center Rijeka

Completed

SLNB After Neoadjuvant Treatment in Node Positive Patients

Sentinel Lymph Node Biopsy | Progression, Disease | Locoregional Neoplasm Recurrence
The First Affiliated Hospital of Guangzhou Medical...

Unknown

Sequential Changes of Serum KL-6 Predict Progression in Interstitial Lung Disease

Interstitial Lung Disease, Desquamative

China
Ankara Education and Research Hospital

Unknown

Factors Related to the Progression of Chronic Kidney Disease

Chronic Kidney Disease

Turkey
Chinese Academy of Medical Sciences, Fuwai Hospital

Recruiting

Intensive Lipid-lowering for Plaque and Major Adverse Cardiovascular Events in Low to Intermediate 10-year ASCVD Risk Population (ILLUMINATION)

Coronary Artery Disease Progression

China
Southeast University, China
Science and Technology Department of Jiangsu Province

Completed

Critical Treatment of Coronary Artery Disease (CTCAD)

Coronary Artery Disease | Coronary Artery Disease Progression

China
Wroclaw Medical University

Completed

Biomarkers of Recurrence and Progression in Non-muscle Invasive Bladder Cancer

Recurrence | Progression | Biomarkers | Bladder Cancer | Non-muscle Invasive Bladder Cancer | Cystoscopy

Poland
Hospices Civils de Lyon

Not yet recruiting

Contrast-enhanced Spectral Mammography (CESM) Early Quantitative Evaluation of Tumoral Response and Pathologic Complete Response Prediction for Localized Breast Cancer Treated by Neoadjuvant Chemotherapy (CERePred)

Breast Cancer

France
Rheumazentrum Ruhrgebiet
PPD; Centocor BV; Trial Coordination Center, 9713 GZ Groningen

Unknown

Examination of Radiographic Progression, Efficacy and Safety of Long-Term Treatment With Infliximab in Patients With Ankylosing Spondylitis

Ankylosing Spondylitis

Belgium, Germany, Finland, France, Netherlands, United Kingdom
Kobe University

Completed

Effect of Rosuvastatin and Eicosapentaenoic Acid on Neoatherosclerosis: The LINK-IT Trial

Coronary Artery Disease Progression
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Proteomics and Genomics Combined With CT to Predict CVD (PREDICT-CVD)

Coronary Artery Disease Progression

Netherlands
Kobe University

Recruiting

To Evaluate the Efficacy of Alirocumab for Neoatherosclerosis by Using OCT, in Comparison With Standard Statin Therapy (POLARIS)

Coronary Artery Disease Progression

Japan
InCor Heart Institute

Unknown

Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease

Coronary Artery Disease Progression

Brazil
Novartis Pharmaceuticals

Recruiting

A NIS of Alpelisib in Combination With Fulvestrant in Postmenopausal Women, and Men, With HR+,HER2- , Locally Advanced or Metastatic Breast Cancer With a PIK3CA Mutation, After Disease Progression Following Endocrine Therapy as Monotherapy, in the Real-world Setting

Hormone Receptor Positive HER2 Negative Breast Cancer With a PIK3CA Mutation

Spain, Italy, Austria
University Hospital Inselspital, Berne

Completed

Predicting Aortic Stenosis Progression by Measuring Serum Calcification Propensity (PASP)

Aortic Valve Stenosis | Valvular Heart Disease | Aortic Valve Sclerosis | Stenosis Progression

Switzerland
Ankara Training and Research Hospital

Completed

In the Prediction of Recurrence and Progression of NMIBC; EORTC or CUETO or Both?

Disease Progression | Bladder Cancer | Recurrent Bladder Cancer

Clinical Trials on Cancer Disease Progression

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Drug Interventions

CROs by country

CROs in Sri Lanka

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Rare Diseases

Drug Interventions

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