Clinical Trials on Cancer of Brain and Nervous System in Japan

Total 1408 results

Takeda

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TAK-925 in Healthy Volunteers and Participants With Narcolepsy

Healthy Participants | Narcolepsy

Japan
Hamamatsu University

Unknown

Pharmacokinetic and Pharmacodynamic Study of S-1 in Patients With Digestive Organ Cancer

Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Colon Cancer

Japan
Kissei Pharmaceutical Co., Ltd.

Completed

Phase II Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)

Spinocerebellar Degeneration

Japan
W.L.Gore & Associates

Recruiting

Japan Post Marketing Surveillance of the GORE® CARDIOFORM Septal Occluder (GSO-PFO PMS)

Stroke | TIA | Cryptogenic Stroke | PFO - Patent Foramen Ovale

Japan
Kyoto University

Withdrawn

Surgery With or Without Hepatic Arterial Chemotherapy in Treating Patients With Liver Cancer

Localized Resectable Adult Primary Liver Cancer | Stage III Childhood Liver Cancer

Japan
Eisai Co., Ltd.

Completed

A Study of Intravenous Perampanel in Japanese Participants With Epilepsy

Epilepsy | Seizures

Japan
Kyowa Kirin Co., Ltd.

Completed

Phase 2 Clinical Study of KW-6500 in Parkinson's Disease Patients With Motor Response Complication on Levodopa Therapy

Parkinson's Disease

Japan
Otsuka Pharmaceutical Co., Ltd.

Recruiting

Samsca Post-marketing General Drug Use-results Survey in Patients With Hyponatremia in SIADH

Antidiuretic Hormone, Inappropriate Secretion

Japan
Kobayashi Shinichiro

Unknown

Bone Microstructure by Using HR-pQCT in Long Courses After Gastrectomy

Gastric Cancer | Sarcopenia | Osteoporosis

Japan
Takeda

Completed

Phase 1 TAK-925 Study in Healthy Adult and Elderly Volunteers and Participants With Narcolepsy

Healthy Participants and Patients With Narcolepsy

Japan
Nagasaki University

Recruiting

Bone Microstructure After Gastrectomy Evaluating by Using HR-pQCT

Gastric Cancer | Sarcopenia | Osteoporosis

Japan
Pfizer

Completed

Multiple Intravenous Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease

Alzheimer's Disease

Japan
GlaxoSmithKline

Completed

Clinical Study of Lamotrigine to Treat Newly Diagnosed Typical Absence Seizure in Children and Adolescents

Epilepsy

Korea, Republic of, Japan
Shire

Completed

Multicenter Study of HGT-1110 Administered Intrathecally in Children With Metachromatic Leukodystrophy (MLD) (IDEAMLD)

Metachromatic Leukodystrophy (MLD)

Australia, Denmark, Japan, France, Germany
Yamaguchi University Hospital
University Hospital Medical Information Network; Japan Clinical Research Support...

Completed

Therapeutic Hypothermia for Severe Traumatic Brain Injury in Japan

Brain Injuries, Traumatic

Japan
Biogen

Completed

Single and Multiple Ascending Dose Study of Aducanumab (BIIB037) in Japanese Participants With Alzheimer's Disease (PROPEL)

Alzheimer's Disease

Japan
UCB Biopharma S.P.R.L.

Completed

A Study to Evaluate the Safety and Tolerability of Intravenous Brivaracetam (BRV) as Replacement for Oral Brivaracetam in Japanese Subjects >=16 Years of Age With Partial Seizures With or Without Secondary Generalization

Epilepsy | Partial Seizures With or Without Secondary Generalization

Japan
GlaxoSmithKline

Completed

Clinical Evaluation of Ropinirole PR/XR Tablets in Monotherapy for Parkinson's Disease (PD)

Parkinson Disease

Japan
Ludwig Institute for Cancer Research
Mie University

Completed

Safety and Immunogenicity of CHP-HER2 and CHP-NY-ESO-1 Protein With OK-432 in Antigen-Expressing Cancers

Stomach Cancer | Breast Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer

Japan
Lundbeck Japan K. K.

Completed

Clinical Study of Desmoteplase in Japanese Patients With Acute Ischemic Stroke (DIAS-J)

Acute Ischemic Stroke

Japan
Yamaguchi University Hospital
Iwate Medical University; Tohoku University; Nakamura Memorial Hospital; Ootemachi...

Completed

Eicosapentaenoic Acid Cerebral Vasospasm Therapy Study (EVAS)

Subarachnoid Hemorrhage | Cerebral Vasospasm

Japan
Eisai Co., Ltd.

Completed

A Randomized, Double-blind, Placebo-controlled Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamic Response of Repeated Intravenous Infusions of BAN2401 in Subjects With Mild Cognitive Impairment Due to Alzheimer's Disease and Mild Alzheimer's Disease

Alzheimer's Disease

Japan
Boehringer Ingelheim

Completed

Non-interventional Study for Real-world Data of Afatinib Treatment in First-line Setting and of Subsequent Therapies for Patients With Advanced Epidermal Growth Factor Receptor (EGFR) Mutation-positive Lung Adenocarcinoma

Non-squamous, Non-Small Cell Lung Cancer

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Dose-ranging Study for SPM 962 in Parkinson's Disease Patients

Parkinson's Disease

Japan
Novartis
Mitsubishi Tanabe Pharma Corporation

Completed

An Extension Study of the Efficacy and Safety of Fingolimod (FTY720) in Patients With Relapsing Multiple Sclerosis

Multiple Sclerosis

Japan
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., Japan

Completed

Trial to Assess the Clinical Efficacy and Safety of MSJ-0011 in Inducing Ovulation in Anovulatory or Oligo-ovulatory Japanese Women

Polycystic Ovarian Syndrome | Anovulation | Oligo-ovulation | Hypothalamic-pituitary Dysfunction

Japan
Shinshu University

Recruiting

To Examine Whether or Not the Primary Causes of OA or RA Might be Bone Alterations

Osteoarthritis of Multiple Joints | Progression of Rheumatoid Arthritis

Japan
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of Two-Dose Series of Menactra® in Japanese Healthy Adult Subjects

Meningitis | Meningococcal Infections | Meningococcal Meningitis

Japan
Boehringer Ingelheim

Recruiting

A Study to Test Different Doses of BI 765049 Alone and in Combination With Ezabenlimab in Asian People With Advanced Cancer (Solid Tumours) Positive for B7-H6

Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Lung Cancer | Gastrointestinal Cancer | Liver Cancer

Japan
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Completed

An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer) (CheckMate 498)

Brain Cancer

United States, Canada, Belgium, Spain, Australia, Netherlands, United Kingdom, Denmark, Norway, Japan, Sweden, France, Poland, Austria, Germany, Israel, Italy, Russian Federation, Switzerland
Biogen

Completed

Natalizumab (BG00002, Tysabri) Study in Japanese Participants With Relapsing-Remitting Multiple Sclerosis (RRMS) (Tysabri Japan)

Multiple Sclerosis

Japan
Novartis
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety of FTY720 in Patients With Relapsing Multiple Sclerosis (MS)

Multiple Sclerosis

Japan
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Reversal of Preneoplastic Metaplasia in the Stomach With MEK Inhibitor

Gastric Cancer | Metaplasia | Stage I Gastric Cancer | Initial-onset Gastric Cancer

Japan
Pfizer

Completed

Study to Evaluate the Immunogenicity, Safety, and Tolerability of a Tick-Borne Encephalitis (TBE) Vaccine in Healthy Japanese Participants 1 Year of Age and Older

Tick-Borne Encephalitis

Japan
GlaxoSmithKline

Completed

REQUIP (Ropinirole Hydrochloride) IR Long-Term Phase 4 Study

Parkinson's Disease | Parkinson Disease

Japan
Novo Nordisk A/S

Enrolling by invitation

An Observational Study of Patients With Moderate Parkinson's Disease (TRANSCEND 1)

Parkinson Disease

United States, Japan, Sweden, United Kingdom
GlaxoSmithKline

Terminated

A Study to Evaluate the Efficacy of 18 to 24mg/Day Ropinirole Controlled Release (CR) Tablets in Early and Advanced Parkinson's Disease (PD) Patients.

Parkinson Disease

Japan
UCB Japan Co. Ltd.

Completed

An Open Label Study of Levetiracetam in Japanese Pediatric Patients With Partial Seizures

Epilepsy | Partial Seizures

Japan
Tokyo University

Completed

Optimal Treatment for Spinal Cord Injury Associated With Cervical Canal Stenosis (OSCIS) Study (OSCIS)

Spinal Cord Injury

Japan
CellSeed Inc.

Terminated

A Study to Evaluate the Esophageal Stenosis Inhibition Effects of CLS2702C/CLS2702D After Endoscopic Submucosal Dissection (ESD) in Patients With Superficial Esophageal Cancer in the Steroid Administration Risk Group

Superficial Esophageal Cancer

Japan
Taewoong Medical Co., Ltd.

Completed

Comparing Covered Self-expandable Metallic Stent (SEMS) Above/Across the Sphincter of Oddi

Pancreatic Cancer | Cancer of Bile Duct

Korea, Republic of, Japan
Chiesi Farmaceutici S.p.A.
ICON plc

Recruiting

Study to Evaluate the Safety, PK, PD, and Efficacy of PRX-102 in Japanese Patients With Fabry Disease (RISE)

Fabry Disease

Japan
Daiichi Sankyo Co., Ltd.

Completed

An Observational Study of CPT-11 Plus Platinum Analogues Regimens and UGT1A1 Genotypes in Solid Tumors

Cervical Cancer | Small Cell Lung Cancer | Ovarian Cancer | Non-small Cell Lung Cancer | Gastric Cancer (Inoperable and Recurrent)

Japan
Translational Research Center for Medical Innovation...

Terminated

Treatment for Acute Spinal Cord Injury

Spinal Cord Injury

Japan
Eli Lilly and Company

Completed

A Study of LY3002813 in Participants With Alzheimer's Disease

Alzheimer Disease

United States, Japan
AbbVie

Recruiting

An Observational Study of Subcutaneous Infusion of ABBV-951 to Assess Change in Disease Activity and Adverse Events In Adult Japanese Participants With Advanced Parkinson's Disease

Parkinson's Disease (PD)

Japan
Ionis Pharmaceuticals, Inc.

Recruiting

A Study to Evaluate the Safety and Efficacy of ION373 in Patients With Alexander Disease (AxD)

Alexander Disease

United States, United Kingdom, Australia, Canada, Israel, Italy, Japan, Netherlands
Astellas Pharma Inc

Completed

An Open Study for Steroid Resistant, Non-Thymectomized MG Patients

Myasthenia Gravis

Japan
UCB Biopharma SRL

Active, not recruiting

A Study to Test the Safety and Tolerability of Brivaracetam in Children and Adolescents With Seizures

Epilepsy

United States, Hungary, Italy, Japan, Mexico, Poland, Spain
InSightec

Recruiting

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

Movement Disorders | Parkinsons Disease | Neurology

United States, Japan

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