Clinical Trials on Cardiomyopathy, Stress in Czechia

Total 64 results

University Hospital, Motol

Completed

Effect of Metoprolol in Post Alcohol Septal Ablation Patients With Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

Czechia
University Hospital Olomouc

Not yet recruiting

CRT-P or CRT-D in Dilated Cardiomyopathy (CRT-REALITY)

Cardiomyopathy, Dilated, 3B

Czechia
MAPS Europe B.V.
Multidisciplinary Association for Psychedelic Studies

Completed

Open Label Study of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-Study

PTSD

Czechia, Germany, Netherlands, Norway, United Kingdom
Palacky University

Recruiting

Effect of Vibroacoustic Therapy on Acute Stress in University Students

Stress, Psychologic

Czechia
National Institute of Mental Health, Czech Republic

Recruiting

Kogito: App to Reduce Perinatal Psychosocial Stress

Depression, Anxiety | Psychological Stress | Perinatal Problems

Czechia
University Hospital Ostrava
Brno University Hospital; University Hospital Olomouc

Terminated

Profitability Trial in Primary Preventive Implantable Cardioverter-defibrillator Recipients (HAPPIER)

Ischaemic Cardiomyopathy | Non-ischaemic Cardiomyopathy

Czech Republic
EBR Systems, Inc.

Completed

Safety and Performance of Electrodes Implanted in the Left Ventricle (SELECT-LV)

Heart Diseases | Cardiovascular Diseases | Heart Failure | Cardiomyopathies | Ventricular Dysfunction

Denmark, Czechia
St. Anne's University Hospital Brno, Czech Republic

Unknown

CZECH-ICIT (CZECH Inflammatory Cardiomyopathy Immunosuppression Trial)

Inflammatory Cardiomyopathy

Czech Republic
Jan Malecek

Completed

Can Ammonium Inhalants Maintain Performance in Sleep Deprived Soldiers?

Sleep | Cognitive Change | Sleep Deprivation | Military Activity | Military Combat Stress Reaction

Czechia
University Hospital Ostrava

Completed

Bioelectrical Impedance in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients

Septic Shock | Respiratory Insufficiency | Hypoxemia | Chronic Obstructive Pulmonary Disease Exacerbation | Lung Ventilator | Hyperhydration | Respiratory Distress Syndrome, Acute

Czechia
Charles University, Czech Republic
AstraZeneca

Unknown

CHANCE - Candesartan in Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

Czech Republic
Palacky University

Completed

Effect of Molecular Hydrogen Administration on Performance and Body Response on Exercise in National-level Fin-swimmers

Oxidative Stress | Athletic Performance | Muscle Fatigue

Czechia
Palacky University

Completed

The Effect of Hydrogen Rich Water Intake on Acute Body Response and Following Recovery After 5 km Run in Untrained Men

Oxidative Stress | Athletic Performance | Muscle Fatigue

Czechia
Brno University Hospital
St. Anne's University Hospital Brno, Czech Republic

Recruiting

The Diagnosis of Superinfections in Mechanically Ventilated Covid-19 Patients (SUPER-BAL)

COVID-19 Pneumonia | ARDS, Human | Superinfection

Czechia
Myopowers Medical Technologies France SAS

Completed

ARTUS MONO Artificial Urinary Sphincter

Urinary Incontinence,Stress

France, Czechia
Myopowers Medical Technologies France SAS
EVAMED; Affluent Medical

Not yet recruiting

Safety and Clinical Performance Study of the ARTUS® Artificial Urinary Sphincter (AUS) (DRY)

Stress Urinary Incontinence

Spain, Czechia
Maastricht University
Medtronic; ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

LVSP vs RVP in Patients With AV Conduction Disorders (LEAP)

Atrioventricular Block | Pacing-Induced Cardiomyopathy | Cardiac Pacing | Conduction System Pacing | Left Ventricular Septal Pacing

Spain, Netherlands, Belgium, Czechia, Italy, Switzerland, Poland
Bristol-Myers Squibb

Active, not recruiting

A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM

Hypertrophic Cardiomyopathy | Non-obstructive Hypertrophic Cardiomyopathy | Obstructive Hypertrophic Cardiomyopathy

Denmark, United States, Belgium, Czechia, France, Germany, Israel, Italy, Netherlands, Poland, Portugal, Spain, United Kingdom
Palacky University

Completed

Effect of Inhaled Molecular Hydrogen on Recovery Process After Downhill Walking on the Treadmill

Inflammation | Oxidative Stress | Muscle Soreness | Muscle Fatigue

Czechia
Institute for the Care of Mother and Child, Prague...

Not yet recruiting

The Role of ARTificial Uterine CONtractions in Perinatal Respiratory Morbidity of Term Infants Delivered by Elective Caesarean Section (ARTCON)

Neonatal Respiratory Distress

Czechia
GT Urological, LLC

Completed

Clinical Investigation of GT UrologIcal, LLC's Artificial Urinary Sphincter (RELIEF II) (RELIEFII)

Male Stress Urinary Incontinence

Australia, Czechia, New Zealand
Cytokinetics

Enrolling by invitation

Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM (FOREST-HCM)

Symptomatic Hypertrophic Cardiomyopathy (HCM)

United States, France, Israel, Spain, United Kingdom, Italy, Portugal, Poland, Hungary, Denmark, Netherlands, Germany, Czechia
Czech Technical University in Prague
Motol University Hospital, Prague

Recruiting

Evaluation of the Impact of SpO2 Averaging Time on Performance of an Automatic FiO2 Control System: a Randomized Study

Neonatal Respiratory Distress | Very Low Birth Weight Infant

Czechia
Czech Technical University in Prague
University Hospital, Motol

Recruiting

PRICO: OPTI Target Range (POSTR)

Neonatal Respiratory Distress | Very Low Birth Weight Infant

Czechia
MyoKardia, Inc.

Completed

Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy (EXPLORER-HCM)

Obstructive Hypertrophic Cardiomyopathy

United States, France, Germany, Czechia, Spain, Belgium, Denmark, Portugal, Netherlands, Israel, Poland, United Kingdom, Italy
Novo Nordisk A/S

Recruiting

A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis

Transthyretin Amyloid Cardiomyopathy (ATTR CM)

United States, Netherlands, Germany, Canada, Czechia, France, Italy, Portugal, Spain
Cytokinetics
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.

Completed

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM (SEQUOIA-HCM) (SEQUOIA-HCM)

Obstructive Hypertrophic Cardiomyopathy (oHCM)

United States, France, Spain, Portugal, Germany, China, United Kingdom, Israel, Netherlands, Denmark, Czechia, Hungary, Italy, Poland
Brno University Hospital
Masaryk University

Completed

Malignant Hyperthermia in Czech Republic: Description of the Biggest Slavonic Group of Patients Investigated for Risk of Malignant Hyperthermia (MHCZECH)

Malignant Hyperthermia

Czechia
Pfizer

Completed

Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy (ATTR-ACT)

Transthyretin (TTR) Amyloid Cardiomyopathy

United States, Spain, Czechia, Canada, Belgium, Netherlands, Germany, Japan, France, United Kingdom, Brazil, Italy, Sweden
Novo Nordisk A/S

Active, not recruiting

A Research Study to Look at How a New Medicine Called NNC6019-0001 Works and How Safe it is for People Who Have Heart Disease Due to Transthyretin (TTR) Amyloidosis

Transthyretin Amyloid Cardiomyopathy (ATTR CM)

United States, Netherlands, Spain, Portugal, Canada, Czechia, France, Germany, Italy, Japan
Pfizer

Completed

Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy

Transthyretin (TTR) Amyloid Cardiomyopathy

United States, Taiwan, Canada, Belgium, Australia, Czechia, Sweden, Spain, Italy, Hong Kong, Germany, Netherlands, United Kingdom, France, Japan, Argentina, Brazil
University Medical Center Goettingen

Completed

Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in Europe (EU-CERT-ICD)

Myocardial Infarction | Coronary Artery Disease | Dilated Cardiomyopathy | Implantable Defibrillator User

Hungary, Poland, Belgium, Bulgaria, Croatia, Czechia, Denmark, Finland, Germany, Greece, Netherlands, Slovakia, Spain, Sweden, Switzerland, United Kingdom
Ancora Heart, Inc.

Recruiting

Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study

Dilated Cardiomyopathy | Heart Failure With Reduced Ejection Fraction (HFrEF)

United States, France, Netherlands, Czechia, Belarus, Belgium, Serbia
Philip Morris Products S.A.

Completed

Reduction of Exposure, Inflammation, and Oxidative Stress Following at Least 2 Years of Switching to THS Use Compared to Cigarette Smoking

Smoking | Inflammation | Oxidative Stress | Smoking Abstinence

Japan, Germany, Czechia, Greece
Brno University Hospital
Masaryk University

Completed

The Practice of Providing Palliative Care in the Situation of the COVID-19 (Coronavirus Disease 2019) Pandemic in Czech Republic (PEOpLe-C19)

Covid19 | Distress, Emotional

Czechia
Ancora Heart, Inc.

Active, not recruiting

Evaluate the Safety and Performance of the AccuCinch® Ventricular Repair System - The CorCinch-EU Study

Heart Failure | Cardiomyopathies

France, Netherlands, Switzerland, Czechia, Poland, Lithuania, Belarus, Belgium, Italy, United Kingdom
Eidos Therapeutics, a BridgeBio company

Active, not recruiting

Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants

Amyloid Cardiomyopathy, Transthyretin-Related

United States, Spain, Australia, Canada, Italy, Netherlands, Ireland, New Zealand, Belgium, Israel, Greece, Korea, Republic of, Czechia, Brazil, Denmark, Portugal, United Kingdom
Applied Therapeutics, Inc.

Active, not recruiting

Safety and Efficacy of AT-001 in Patients With Diabetic Cardiomyopathy

Diabetic Cardiomyopathies

United States, France, Spain, Australia, Canada, United Kingdom, Germany, Czechia, Hong Kong, Poland
Alexion Pharmaceuticals, Inc.

Recruiting

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM (DepleTTR-CM)

Transthyretin Amyloid Cardiomyopathy

United States, Spain, United Kingdom, Norway, Israel, Korea, Republic of, Belgium, France, Germany, Italy, Japan, China, Australia, Argentina, Austria, Taiwan, Switzerland, Canada, Sweden, Poland, Denmark, Turkey, Brazil, Netherlands, G... and more
Eidos Therapeutics, a BridgeBio company

Completed

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy (ATTRibute-CM)

Heart Diseases | Amyloidosis | Cardiomyopathies | Transthyretin Amyloidosis | Amyloid Cardiomyopathy

United States, Netherlands, Ireland, Canada, Italy, Spain, Belgium, New Zealand, Israel, Australia, Portugal, Brazil, Poland, Czechia, Denmark, Greece, Korea, Republic of, United Kingdom
Ionis Pharmaceuticals, Inc.

Active, not recruiting

CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

United States, Australia, Spain, Canada, Germany, Japan, Italy, Israel, Argentina, France, Portugal, Austria, Brazil, Greece, United Kingdom, Czechia, Sweden, Belgium, Denmark, Poland, Puerto Rico
Rostrum Medical Innovations Inc.
Medical Initiatives

Not yet recruiting

Evaluation of VQm PHM on Pulmonary Health Parameters for ICU

Stroke | Pneumonia | COPD | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Ventilators, Mechanical

France, United States, Austria, Czechia
Bristol-Myers Squibb

Recruiting

A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy (MEMENTO)

Cardiomyopathy, Hypertrophic

United States, Argentina, Australia, Belgium, Canada, Czechia, Hungary, Poland, Switzerland, France, Austria, Finland, Germany, Greece, Italy, Spain, United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

Efficacy of Combining Prophylactic Curosurf With Early Nasal CPAP in Delivery Room: the Curpap Study (Curpap)

Respiratory Distress Syndrome, Newborn

Italy, Spain, Czechia, France, Portugal
Institute for Clinical and Experimental Medicine

Completed

Postprandial Insulin Secretion, Oxidative Stress and Gastrointestinal Peptides in Patients With Type 2 Diabetes Versus Healthy Subjects

Type 2 Diabetes | Postprandial Oxidative Stress

Czech Republic
Bristol-Myers Squibb

Active, not recruiting

A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy (ODYSSEY-HCM)

Cardiomyopathy, Hypertrophic

Spain, Austria, Belgium, Brazil, Canada, Denmark, France, Germany, Hungary, Israel, Japan, Netherlands, Norway, Poland, Portugal, United Kingdom, United States, Australia, China, Czechia, India, Italy, Korea, Republic of
Vericel Corporation

Completed

Superiority of MACI® Versus Microfracture Treatment in Patients With Symptomatic Articular Cartilage Defects in the Knee (SUMMIT)

Articular Cartilage Defect

Netherlands, Norway, France, Czechia, Sweden, Poland, United Kingdom
Alnylam Pharmaceuticals

Active, not recruiting

APOLLO-B: A Study to Evaluate Patisiran in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Australia, Brazil, Bulgaria, France, Italy, Japan, Mexico, Netherlands, Taiwan, United Kingdom, Belgium, Czechia, Denmark, New Zealand, Sweden, Korea, Republic of, Argentina, Chile, Hong Kong, Portugal
University Hospital, Motol

Unknown

Impact of Immunonutrition on the Patients With Cystic Fibrosis

Malnutrition | Cystic Fibrosis | Oxidative Stress

Czech Republic
Alnylam Pharmaceuticals

Active, not recruiting

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Poland, Argentina, Australia, Belgium, France, Germany, Japan, Netherlands, Portugal, Spain, Sweden, United Kingdom, Canada, Czechia, Denmark, Hungary, Ireland, Norway, Korea, Republic of, Austria, Croatia, Israel, Latvia, Lithuan... and more

Clinical Trials on Cardiomyopathy, Stress in Czechia

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