Clinical Trials on Central Core Disease

Total 428452 results

Hellenic Cooperative Oncology Group

Active, not recruiting

Melanoma: Genomic Profiles, Molecular Markers and Therapeutic Implications

Melanoma

Greece
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Completed

Yervoy® Postmarketing Surveillance for Patients in Japan With Unresectable, Malignant Melanoma

Melanoma

Japan
Fondazione Melanoma Onlus

Completed

Vemurafenib Plus Cobimetinib Plus PEG-interferon in Advanced Melanoma Patients Harboring the V600BRAF Mutation (VEMUPLINT)

Melanoma

Italy
Bristol-Myers Squibb

Completed

A Study is to Understand the Treatment Patterns for Immunotherapy Agents and BRAF/MEK Inhibitors Used in the Treatment of Advanced Melanoma

Melanoma

United States
MacroGenics
Massachusetts General Hospital

Terminated

Tissue Procurement Substudy for Participants in Study CP-MGA271-01

Melanoma

United States
University of Birmingham
Medical Research Council; Janssen, LP; Department of Health, United Kingdom

Completed

A Clinical Trial of AdNRGM Plus CB1954 in Prostate Cancer (AdUP)

Prostate Cancer

United Kingdom
Michael Weichenthal

Terminated

PTK/ZK in Disseminated Malignant Melanoma

Melanoma

Germany
Radboud University Medical Center

Completed

myDC/pDC in Stage III Melanoma Patients

Melanoma

Netherlands
Bristol-Myers Squibb

Active, not recruiting

A Study of Patients Receiving Adjuvant Nivolumab Therapy for Melanoma That Has Been Removed

Melanoma

Belgium, Luxembourg
M.D. Anderson Cancer Center

Completed

Tumor and Vaccine Site With a Toll Like Receptor (TLR) Agonist

Melanoma

United States
Bristol-Myers Squibb

Completed

Nivolumab Combined With Ipilimumab Followed by Nivolumab Monotherapy as First-Line Treatment for Patients With Advanced Melanoma (CheckMate 401)

Melanoma

Australia, France, Italy, Belgium, Finland, Austria, Ireland, Sweden, Switzerland, United Kingdom, Germany, Norway
Northwestern University
Sarah M. Friedewald, MD; Jennifer N. Choi, MD

Completed

Skin Self-Examination Education During Mammography (SSE)

Melanoma

United States
Novartis Pharmaceuticals

Completed

Safety of TKI258 in Advanced/Metastatic Melanoma Subjects

Melanoma

United States
Novartis Pharmaceuticals

Completed

A Study Comparing Trametinib and Dabrafenib Combination Therapy to Dabrafenib Monotherapy in Subjects With BRAF-mutant Melanoma

Melanoma

Canada, Spain, United Kingdom, Netherlands, United States, Argentina, Australia, France, Germany, Greece, Italy, Russian Federation, Sweden, Ukraine
Region Skane

Completed

New Biopsy Needle - Evaluation of Prostate Biopsy Quality

Prostate Cancer (Diagnosis)

Sweden
University of California, San Francisco
Merck Sharp & Dohme LLC; OncoSec Medical Incorporated

Completed

Trial of pIL-12/MK-3475 in Metastatic Melanoma

Melanoma

United States
Exosome Diagnostics, Inc.

Completed

Clinical Evaluation of the 'ExoDx Prostate IntelliScore' (EPI)

Cancer of Prostate

United States
Bristol-Myers Squibb

Completed

A Safety and Efficacy Study of Multiple Administration Regimens for Nivolumab Plus Ipilimumab in Subjects With Melanoma

Melanoma

Italy, France, Spain, Australia
Universitaire Ziekenhuizen KU Leuven

Completed

Study of Safety, Tolerability and Immunogenicity of Gardasil®9 in Immunocompromised Patients

Hiv | Human Papilloma Virus | Organ Transplants

Belgium
GlaxoSmithKline

Completed

A Study to Test the Benefit of a New Anti-cancer Treatment in Patients With Unresectable Advanced Melanoma (PREDICT)

Melanoma

United States, Spain, Germany, France, Poland, Italy, Ireland, Russian Federation
Cambridge University Hospitals NHS Foundation Trust
University of Oxford; National Institute for Health Research, United Kingdom; Oxford University Hospitals NHS Trust

Completed

Continuous vs Intermittent Dabrafenib Plus Trametinib in BRAFV600 Mutant Stage 3 Unresectable or Metastatic Melanoma (INTERIM)

Melanoma

United Kingdom
University Hospital, Montpellier

Completed

Uterine Rupture During Labor Among Women With a Prior Cesarean Delivery

Uterine Rupture | Mode of Delivery

France
Loyola University
National Cancer Institute (NCI)

Active, not recruiting

Transfer of Genetically Engineered Lymphocytes in Melanoma Patients

Melanoma

United States
National Cancer Institute (NCI)

Completed

Sun Exposure and Melanoma in Agricultural Workers

Melanoma

United States
Philip Friedlander
Genentech, Inc.

Terminated

The Effects of Treatment With Vemurafenib on the Immune System in Advanced Melanoma

Melanoma

United States
M.D. Anderson Cancer Center
Schering-Plough

Completed

Temozolomide Alone or With Pegylated Interferon-Alpha 2b (PGI) in Melanoma Patients

Melanoma

United States
Biocad

Unknown

International Trial of the Efficacy and Safety of BCD-100 in Patients With Melanoma (MIRACULUM)

Melanoma

Russian Federation
M.D. Anderson Cancer Center

Completed

Melanoma Risk-Reduction Among Patients and Family Members

Melanoma

United States
Bristol-Myers Squibb

Completed

A Single-Arm, Open-Label, Multicenter Clinical Trial With Nivolumab (BMS-936558) for Subjects With Histologically Confirmed Stage III (Unresectable) or Stage IV Melanoma Progressing Post Prior Treatment Containing an Anti-CTLA4 Monoclonal Antibody (CheckMate 172)

Melanoma

Germany, Italy, Sweden, United Kingdom, Belgium, Netherlands, Spain, Finland, Austria, Ireland, Poland, Portugal, Russian Federation, Switzerland, Czechia, Greece, Hungary, Luxembourg, Norway, Romania
Tactile Medical
Vanderbilt University

Completed

A Pilot Study to Evaluate the Feasibility and Potential Effectiveness of the Flexitouch System Head and Neck Treatment

Head and Neck Cancer | Head and Neck Neoplasms | Head and Neck Lymphedema

United States
Atridia Pty Ltd.

Completed

A Phase 1 Trial of SHR3680 With or Without SHR3162 in Prostate Cancer

Prostate Cancer | Neoplasm

Australia
Memorial Sloan Kettering Cancer Center
Novartis; National Comprehensive Cancer Network

Completed

Adjuvant Dabrafenib (GSK2118436) in Patients With Surgically Resected AJCC Stage IIIC Melanoma Characterized by a BRAFV600E/K Mutation

Melanoma

United States
NYU Langone Health

Terminated

A Phase 1b Study of the Selective HDAC Inhibitor Mocetinostat in Combination With Ipilimumab and Nivolumab in Patients With Unresectable Stage III or Stage IV Melanoma

Melanoma

United States
NYU Langone Health
Celldex Therapeutics

Terminated

Study of CDX-3379, a Human Monoclonal Antibody Targeting ERBB3, in Combination With the MEK Inhibitor, Trametinib, in Patients With Advanced Stage NRAS Mutant and BRAF/NRAS Wildtype (WT) Melanoma

Melanoma

United States
McGill University Health Centre/Research Institute...
Jewish General Hospital

Completed

Effect of Early Compression and Exercise on Lymphedema Incidence in Patients With Gynecological Cancer

Genital Neoplasms, Female | Lymphedema

Canada
Grupo Español Multidisciplinar de Melanoma
Roche Farma, S.A; Pivotal S.L.

Completed

Clinical Trial to Evaluate the Efficacy of Vemurafenib in Combination With Cobimetinib (Continuous and Intermittent) in BRAFV600-mutation Positive Patients With Unresectable Locally Advanced or Metastatic Melanoma

Melanoma

Spain
Adil Daud
National Comprehensive Cancer Network

Completed

Trametinib With GSK2141795 in BRAF Wild-type Melanoma

Melanoma

United States
Mayo Clinic

Completed

Neoadjuvant Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Cutaneous Stage L-lll Melanoma

Melanoma

United States
Halozyme Therapeutics

Terminated

Study of PEGPH20 With Cisplatin (CIS) and Gemcitabine (GEM); PEGPH20 With Atezolizumab (ATEZO), CIS, and GEM; and CIS and GEM Alone in Participants With Previously Untreated, Unresectable, Locally Advanced, or Metastatic Intrahepatic and Extrahepatic Cholangiocarcinoma and Gallbladder Adenocarcinoma

Cholangiocarcinoma Non-resectable | Cholangiocarcinoma, Extrahepatic | Cholangiocarcinoma, Intrahepatic | Gallbladder Adenocarcinoma

United States, Korea, Republic of, Thailand
H. Lee Moffitt Cancer Center and Research Institute
GlaxoSmithKline; Oncovir, Inc.

Terminated

Phase II Study to Assess the Safety and Immunogenicity of recMAGE-A3+AS15 ASCI With or Without Poly IC:LC

Melanoma

United States
Novartis Pharmaceuticals

No longer available

An Expanded Treatment Protocol (ETP) of Midostaurin (PKC412) in Patients 18 Years of Age or Older With Newly-diagnosed FLT3-mutated Acute Myeloid Leukemia (AML)

FLT3-mutated Acute Myeloid Leukemia

Canada
M.D. Anderson Cancer Center
American Cancer Society, Inc.

Completed

Targeted Intervention for Melanoma Prevention

Melanoma

United States
Pfizer

No longer available

Expanded Access /Compassionate Use Protocol For Relapsed Or Refractory CD33 Positive AML Patients In The USA Without Access To Comparable Or Alternative Therapy (AML)

CD33 Positive Acute Myelogenous Leukemia

United States
Merck Sharp & Dohme LLC

Terminated

SCH 54031 PEG12000 Interferon Alfa-2b (PEG Intron, MK-4031) vs. INTRON®A (SCH 30500, MK-2958) as Adjuvant Therapy for Melanoma (C98-135, MK-4031-002)

Melanoma
Hospices Civils de Lyon

Completed

Assessment of Supersonic Imagine Aixplorer for the Detection and Localisation of Prostate Cancer Foci (PROSTATE SSI)

Cancer of Prostate

France
Tactile Medical

Completed

Response to Intermittent Pneumatic Compression Therapy in Head and Neck Cancer-Related Lymphedema

Head and Neck Cancer | Head and Neck Neoplasms | Head and Neck Lymphedema

United States
Memorial Sloan Kettering Cancer Center

Completed

Magnetic Resonance Spectroscopic Imaging of the Prostate at 3 Tesla

MRI | Prostate Cancer

United States
Medical University of Vienna

Unknown

Genetic Risk Factors and Acquired Oncogenic Mutations of Melanoma (M3)

Melanoma

Austria
Georgetown University
Genentech, Inc.; Melanoma Research Alliance

Terminated

The Effects of Vemurafenib + Cobimetinib on Immunity in Patients With Melanoma

Melanoma

United States
Bristol-Myers Squibb

Completed

PAN-EU Utilization, Effectiveness and Safety of Ipilimumab Administered in EAP Patients With Advanced Melanoma

Melanoma

Italy, Netherlands, Russian Federation, Czechia, Hungary, Ireland, Norway, Spain, Switzerland, Austria, Germany, Denmark, France, Belgium, United Kingdom, United States

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