Clinical Trials on Central Nervous System Infections in United Kingdom

Total 64072 results

University of Southampton
University Hospital Southampton NHS Foundation Trust

Completed

Challenge of the Nasopharynx With Neisseria Lactamica Expressing the Meningococcal Protein Neisseria Adhesin A (NadA) (NadA-Lac4)

Meningitis, Bacterial | Neisseria Infection

United Kingdom
Valneva Austria GmbH

Withdrawn

Immune Response in IXIARO Batch JEV09L37 Recipients Before and After Revaccination

Japanese Encephalitis

United Kingdom
University of Liverpool

Completed

Flavivirus Cross-priming Potential of IMOJEV (FlaviPrime)

Japanese Encephalitis

United Kingdom
University of Southampton
University Hospital Southampton NHS Foundation Trust

Unknown

A Controlled Study to Assess Safety, Colonisation and Immunogenicity of Reconstituted Lyophilised Neisseria Lactamica (Lac5-Nasal)

Meningitis, Bacterial

United Kingdom
University of Southampton
University Hospital Southampton NHS Foundation Trust

Completed

Defining the Immune Response to Nasopharyngeal Colonisation by the Commensal Neisseria Lactamica (Lac-7)

Meningitis, Bacterial

United Kingdom
University of Surrey

Completed

Cervicovaginal Immune Responses to 3 Deltoid or Thigh Intramuscular (IM) TicoVac (CRC306)

Tick-Borne Encephalitis

United Kingdom
St George's, University of London

Unknown

Evaluation of Safety and Immunogenicity of Meningococcal B and Meningococcal ACWY Vaccine in at Risk Population (ProPositive)

HIV Infections | Hiv | Meningitis, Meningococcal

United Kingdom
University Hospital Southampton NHS Foundation...
University of Southampton

Unknown

A Study Assessing Colonisation & Immunogenicity After Nasal Inoculation With N. Lactamica and Eradication on Day 4 or 14 (Lac-3)

Meningitis, Meningococcal

United Kingdom
Chiron Corporation

Unknown

Kinetic of Immune Memory Response After Re-Vaccination With Meningococcal Vaccine

Meningococcal Disease; Meningococcal Meningitis

United Kingdom
Medical Research Council

Completed

PRION-1: Quinacrine for Human Prion Disease

Prion Disease

United Kingdom
Imperial College London
Biogen; Invicro

Completed

TSPO PET as a Measure of Post-stroke Brain Inflammation: a Natural History Cohort

Inflammatory Response | Stroke, Ischemic | Stroke, Acute

United Kingdom
University of Edinburgh
NHS Lothian; Department of Health, United Kingdom

Unknown

Enhanced CJD Surveillance in the Older Population

Dementia | Prion Disease

United Kingdom
Belfast Health and Social Care Trust
Barts & The London NHS Trust; University Hospitals, Leicester; Bristol Royal... and other collaborators

Completed

Febrile Infants - Diagnostic Assessment and Outcome (FIDO)

Bacterial Infections | Urinary Tract Infections | Meningitis, Bacterial

United Kingdom, Ireland
Novartis
Novartis Vaccines

Completed

Persistence of Immune Response After Vaccination With MCC

Prevention of Meningococcal Infection

United Kingdom
Prof. Elizabeth Miller
Novartis Vaccines

Completed

Study of Meningococcal B Vaccine and ACWY Conjugate Vaccine in Healthy Adults (MenOccy)

Meningococcal Meningitis, Serogroup A | Meningococcal Meningitis, Serogroup B | Meningococcal Meningitis, Serogroup C | Meningococcal Meningitis, Serogroup Y | Meningococcal Meningitis, Serogroup W

United Kingdom
Belfast Health and Social Care Trust
Queen's University, Belfast; Royal College of Emergency Medicine; Pediatric Emergency... and other collaborators

Completed

Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA. (PIC)

Sepsis | Meningitis, Meningococcal | Meningitis | Meningococcal Infections | Meningococcal Disease | Meningococcal Sepsis

United Kingdom
Novartis Vaccines

Completed

Persistence of Antibodies and Kinetics of B Cell Response in Healthy Children After Vaccination With MCC Vaccine

Prevention of Meningococcal Infection

United Kingdom
Novartis
Novartis Vaccines

Completed

Kinetics of B Cell Response in Infants Menjugate Vaccination

Prevention of Meningococcal Infection

United Kingdom
Public Health England

Withdrawn

Host-pathogen Interactions in Meningococcal Disease: Finding the Key That Fits the Lock (Lock and Key)

Meningitis

United Kingdom
Sanofi Pasteur, a Sanofi Company

Completed

Study of Antibody Responses After a Dose of Tetravalent Meningococcal Diphtheria Conjugate Vaccine in Children

Meningitis | Meningococcemia

United Kingdom
Public Health England

Completed

Comparison of Two Meningococcal ACWY Conjugate Vaccines (PRIME)

Meningococcal Meningitis

United Kingdom
Imperial College London
Medical Research Council

Terminated

The HAM Infliximab Study (HAM06)

HTLV-I-associated Myelopathy

United Kingdom
Kasey Phifer

Terminated

PEMF Therapy to Treat Lingering Symptoms of Lyme Disease After Treatment With Antibiotics (PEMF)

Lyme Disease | Lyme Arthritis | Lyme Neuroborreliosis | Unknown Origin Fever

United Kingdom
University of Oxford

Completed

An Alternative Booster Vaccine Against Meningitis and Ear Infections

Invasive Streptococcus Pneumoniae Disease

United Kingdom
University of Oxford

Completed

Understanding the Immune Response to Two Different Meningitis Vaccines

Meningitis | Meningococcal Disease | Septicaemia

United Kingdom
University of Oxford

Active, not recruiting

Sero-epidemiological Survey of England in 2019/2020 - COVID-19 (STORY)

COVID-19 | Diphtheria | Serogroup C Meningococcal Meningitis

United Kingdom
University of Oxford
Novartis Vaccines

Completed

Understanding the Immune Response to Meningitis Vaccines

Meningitis | Septicemia

United Kingdom
Imperial College London
Medical Research Council; Imperial College Healthcare NHS Trust; University Hospital...

Completed

Ciclosporin in HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP) (HAM05)

HTLV I Associated Myelopathy

United Kingdom
Imperial College London

Completed

Zidovudine Plus Lamivudine in HTLV-I-associated Myelopathy: a Randomised Trial

HTLV-I-associated Myelopathy

United Kingdom
St George's, University of London
Wings for Life; Neurosciences Research Foundation

Completed

Injured Spinal Cord Pressure Evaluation Study - Transverse Myelitis (ISCoPE-TM)

Transverse Myelitis

United Kingdom
Oxford University Hospitals NHS Trust

Completed

Oral Versus Intravenous Antibiotics for Bone and Joint Infections (OVIVA B&J) (OVIVA)

Bone Infection | Joint Infection

United Kingdom
Iva Hauptmannova

Terminated

Extramembranous and Interosseous Technique of Tibialis Posterior Tendon Transfer

Cerebral Palsy | Poliomyelitis | Nerve Injury | Leprosy | Muscle Injury

United Kingdom
Imperial College London
Medical Research Council

Terminated

Novel Interventions in HIV-1 Infection (IMIRC1003)

HIV-1 Infection

United Kingdom
AiCuris Anti-infective Cures AG

Completed

Thorough QT/QTc of Pritelivir in Healthy Subjects

HSV Infection

United Kingdom
Public Health England

Completed

Pertussis and Meningitis C Concomitant Vaccination in Adolescents (Mutliboost)

Pertussis | Meningitis | Immunization | Preventive Immunization; Meningitis

United Kingdom
National Institutes of Health Clinical Center (CC)

Completed

Natural History of West Nile Virus Infection

Encephalitis | Myelitis | West Nile Virus

United States
University College, London

Active, not recruiting

Testing for Tuberculosis in the United Kingdom HIV Infected Population

HIV | Latent Tuberculosis

United Kingdom
NHS Blood and Transplant
Irish Blood Transfusion Service; Welsh Blood Service; Scottish National Blood...

Completed

Notification of Donors With Positive Microbiology Markers

Hepatitis B | Hepatitis C | Human Immunodeficiency Virus | Creutzfeldt-Jakob Syndrome | Human T-lymphotropic Virus I & II

United Kingdom
University of Oxford
GlaxoSmithKline; ReiThera Srl

Completed

A Study to Assess the Safety of HIV and Hep C Vaccine Candidates When Given Separately or in Combination

HIV Infection | Hepatitis C Infection

United Kingdom
University College, London

Unknown

Group CST Using Zoom: A Proof of Concept Study

Dementia

United Kingdom
Portsmouth Hospitals NHS Trust
University of Portsmouth

Completed

Biofilm Composition as a Predictive Biomarker for Prosthetic Joint Infection (Biofilms)

Joint Infection

United Kingdom
University of East Anglia
Quadram Institute Bioscience; Invest in ME Research UK

Unknown

Autoimmunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Chronic Fatigue Syndrome | Myalgic Encephalomyelitis

United Kingdom
Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Completed

A Phase 2a Study to Evaluate EDP-938 in the Virus Challenge Model

RSV Infection

United Kingdom
Hvivo
GlaxoSmithKline

Completed

RSV Study in Adults 60 to 75 Years of Age

RSV Infection

United Kingdom
Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Recruiting

A Controlled Phase 2a Study to Evaluate the Efficacy of EDP-323 Against Respiratory Syncytial Virus Infection in a Virus Challenge Model

RSV Infection

United Kingdom
Imperial College London

Recruiting

The Impact of Age on Adaptive Immunity in Adults Infected With Respiratory Syncytial Virus (INFLAMMAGE)

RSV Infection

United Kingdom
Bavarian Nordic

Completed

Phase 2a Study of MVA-BN-RSV Vaccination and RSV Challenge in Healthy Adults

RSV Infection

United Kingdom
Meissa Vaccines, Inc.
Hvivo

Completed

Human Challenge Study to Evaluate the Efficacy of MV-012-968 Vaccine

RSV Infection

United Kingdom
Alios Biopharma Inc.

Completed

A Phase 2a Study to Evaluate ALS-008176 in the Virus Challenge Model

Respiratory Syncytial Virus Infections

United Kingdom
Axcella Health, Inc

Completed

Efficacy, Safety, Tolerability of AXA1125 in Fatigue After COVID-19 Infection

Post-Acute Sequelae of SARS-CoV-2 (PASC) Infection

United Kingdom

Clinical Trials on Central Nervous System Infections in United Kingdom

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