Clinical Trials on Central Nervous System Protozoal Infections

Total 166742 results

Pfizer
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDS

HIV Infections | Toxoplasmosis, Cerebral

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome

Completed

A Study of Pyrimethamine in the Treatment of Infection by a Certain Parasite in HIV-Positive Patients

HIV Infections | Toxoplasmosis, Cerebral

United States
Douglas Postels, MD, MS
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

DON in Pediatric Cerebral Malaria

Malaria, Cerebral

Malawi
U.S. Army Medical Research and Development Command

Completed

Study of the Safety of Intravenous Artesunate

Malaria | Malaria, Cerebral

United States
U.S. Army Medical Research and Development Command
Walter Reed Army Institute of Research (WRAIR)

Completed

Study of the Safety of Intravenous Artesunate

Malaria | Malaria, Cerebral

United States
Makerere University

Unknown

Mannitol as Adjunct Therapy for Childhood Cerebral Malaria

Cerebral Malaria

Uganda
Claude Bernard University

Unknown

Randomized Trial of Erythropoietin During Cerebral Malaria (EPOMAL)

Cerebral Malaria

Mali
Makerere University
Ministry of Health, Uganda; Sanofi-Synthelabo

Unknown

Efficacy of Intrarectal Versus Intravenous Quinine for the Treatment of Childhood Cerebral Malaria

Cerebral Malaria

Uganda
National Institute of Allergy and Infectious Diseases...

Completed

A Randomized Prospective Study of Pyrimethamine Therapy for Prevention of Toxoplasmic Encephalitis in HIV-Infected Individuals With Serologic Evidence of Latent Toxoplasma Gondii Infection

HIV Infections | Toxoplasmosis, Cerebral

United States
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Diagnosis of Toxoplasma Gondii Infection by Exploration of Cellular Immunity (TOXCELL) (TOXCELL)

Toxoplasmosis | Toxoplasmosis, Congenital | Toxoplasma Infections | Toxoplasmosis Recurrent

France
Universitas Padjadjaran

Recruiting

Dexamethasone for Cerebral Toxoplasmosis (De-Tox)

Toxoplasmosis, Cerebral

Indonesia
University of Oxford
Chittagong Medical College and Hospital

Completed

Severe and Cerebral Malaria Investigated Through Host Metabolomics

Severe Malaria

Bangladesh
University of Rochester
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Enteral Levetiracetam For Seizure Control In Pediatric Cerebral Malaria (LVT1)

Epilepsy | Seizure | Cerebral Malaria

Malawi
National Institute of Allergy and Infectious Diseases...

Completed

Primary Prophylaxis of Cerebral Toxoplasmosis in HIV-Infected Patients

HIV Infections | Toxoplasmosis, Cerebral

United States
Michigan State University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Treating Brain Swelling in Pediatric Cerebral Malaria (TBS)

Malaria, Cerebral

Malawi
Epicentre
Harvard Medical School (HMS and HSDM); Massachusetts General Hospital; Mbarara... and other collaborators

Completed

Evaluation of the Efficacy and Safety of Inhaled Nitric Oxide as Adjunctive Treatment for Cerebral Malaria in Children

Malaria, Cerebral

Uganda
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Prognosis of Disseminated and Cerebral Toxoplasmosis Hospitalized in Intensive Care in the Era of PCR Diagnosis (TOXIC)

Toxoplasmosis

France
University Hospital, Limoges

Completed

Cerebral Toxoplasmosis and AIDS (TOXODFA)

AIDS | Cerebral Toxoplasmosis

France
University of Rochester
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

A Safety and Feasibility Study of Enteral LVT vs. Standard of Care for Seizure Control in Pediatric CM (LVT2)

Epilepsy | Seizure | Cerebral Malaria

Malawi
Hospices Civils de Lyon

Recruiting

Lyon Cohort of Maternal and Congenital Toxoplasma Infections

Toxoplasmosis, Congenital

France
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome; Upjohn

Completed

A Pilot Study of Oral Clindamycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDS

HIV Infections | Toxoplasmosis, Cerebral

United States
National Institute of Allergy and Infectious Diseases...

Completed

Phase II Randomized Open-Label Trial of Atovaquone Plus Pyrimethamine and Atovaquone Plus Sulfadiazine for the Treatment of Acute Toxoplasmic Encephalitis

HIV Infections | Toxoplasmosis, Cerebral

United States
Palo Alto Medical Foundation

Completed

Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse

HIV Infections | Toxoplasmosis, Cerebral

United States
Makerere University
Karolinska Institutet

Completed

Rehabilitation Program for Cognitive Deficits in Ugandan Children After Cerebral Malaria

Malaria, Cerebral

Uganda
Assistance Publique - Hôpitaux de Paris

Unknown

New Diagnostic Approach for Congenital Toxoplasmosis (TOXODIAG)

Congenital Toxoplasmosis

France
Assistance Publique - Hôpitaux de Paris

Completed

Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During Pregnancy (TOXOGEST)

Congenital Toxoplasmosis

France
Centre Hospitalier Universitaire Dijon

Terminated

Assessment of Two Therapeutic Strategies in the Treatment of Children With Congenital Toxoplasmosis (TOSCANE)

Congenital Toxoplasmosis

France
National Institute of Allergy and Infectious Diseases...
University of Chicago

Recruiting

Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis

Toxoplasmosis

United States
Hospices Civils de Lyon

Recruiting

Pregnancy and Congenital Toxoplasmosis (GRETA)

Congenital Toxoplasmosis | Retinochoroiditis

France
Institute of Tropical Medicine, Belgium
University Hospital, Geneva; Institut National de Recherche Biomédicale. Kinshasa...

Completed

Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC (Nidiag-Neuro)

Neurological Disorders | Bacterial Meningitis | Cryptococcal Meningitis | Neurosyphilis | Cerebral Malaria | Central Nervous System Tuberculosis

Congo, The Democratic Republic of the
Glaxo Wellcome

Completed

A Pilot Study of 566C80 for the Salvage Treatment of Toxoplasmic Encephalitis in Patients Infected With the Human Immunodeficiency Virus (HIV) Who Have Failed or Are Intolerant of Pyrimethamine-Sulfadiazine

HIV Infections | Toxoplasmosis, Cerebral

United States, Canada
St George's, University of London
Institut Pasteur; European and Developing Countries Clinical Trials Partnership... and other collaborators

Completed

Driving Reduced AIDS-associated Meningo-encephalitis Mortality (DREAMM)

Bacterial Meningitis | AIDS-Related Opportunistic Infections | Meningo-encephalitis | Cryptococcal Meningitis | Tuberculous Meningitis | Cerebral Toxoplasmosis

Cameroon, Malawi, Tanzania
University of Utah
National Institute of Allergy and Infectious Diseases (NIAID); Duke University and other collaborators

Completed

Hyperphenylalaninemia in Cerebral Malaria

Plasmodium Falciparum Malaria

Tanzania
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of ABO809 in Healthy Participants

Cryptosporidium Infection, Cryptosporidiosis

United States
London School of Hygiene and Tropical Medicine
Population Services International

Unknown

Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDR

Japanese Encephalitis | Malaria | Dengue

Lao People's Democratic Republic
GlaxoSmithKline
PATH; Iqvia Pty Ltd; AMP (Agence de Médecine Préventive) (in French); RAFT (Réseau... and other collaborators

Completed

A Surveillance Study of Diseases Specified as Adverse Events of Special Interest, of Other Adverse Events Leading to Hospitalisation or Death, and of Meningitis in Children in Africa Prior to Implementation of the RTS,S/AS01E Candidate Vaccine

Malaria | Malaria Vaccines

Ghana, Burkina Faso, Kenya
Wei Zhao
Beijing Children's Hospital

Unknown

A Study the Population Pharmacokinetics of Children of Infectious Disease in Central Nervous System

Central Nervous System Infection

China
Karolinska University Hospital
Karolinska Institutet; Region Stockholm

Recruiting

Novel Diagnostic Methods to Identify External Ventricular Drain Associated Infections (EVD Infect II)

Infection, Bacterial | Nosocomial Infection | Ventriculitis, Infectious | Ventricular Drain Related Infection

Sweden
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy...

Completed

Differences in Malaria Infection Levels in HIV-infected Infants and Children Receiving PI- and NNRTI-based HAART

HIV Infections | Malaria

Uganda, Malawi, Zambia
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Intestinal Protozoal Infections and Sexual Transmitted Diseases Among Targeted Cohorts

HIV Infections | Protozoan Infections

Taiwan
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy...

Terminated

Pharmacology of Antimalarial Therapy With or Without Antiretroviral Therapy

HIV Infection | Malaria

Malawi, Uganda
Tulane University Health Sciences Center
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Trichomonas Vaginalis Recurrence Among HIV+ Women

HIV Infections | Trichomonas Infections

United States
Mennonite Christian Hospital

Unknown

Seroepidemiology of Japanese Encephalitis Virus Infection in Hualien, Taiwan

Japanese Encephalitis
Sohag University

Unknown

Vitamin D Estimation With Giardia Lamblia Infections

Giardia Lamblia Infection

Egypt
University of Texas, El Paso
National Institute of Allergy and Infectious Diseases (NIAID); Drugs for Neglected... and other collaborators

Active, not recruiting

New Therapies and Biomarkers for Chagas Infection (TESEO)

Chagas Disease | Trypanosoma Cruzi Infection

Bolivia
Pfizer

Completed

Anaemetro I.V. Infusion 500mg Drug Use Investigation

Anaerobic Infection | Infectious Enterocolitis | Amebic Dysentery
PaijatHame Central Hospital
University of Turku

Unknown

Lymphocytic Herpesviruses and Cerebrospinal Fluid Polymerase Chain Reaction (PCR)

Central Nervous System Infection

Finland
National Institute of Allergy and Infectious Diseases...

Completed

A Systems Biology Approach to Malaria Immunity

Plasmodium Falciparum Infection

United States
Radboud University Medical Center
London School of Hygiene and Tropical Medicine; Imperial College London; University... and other collaborators

Completed

Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen Repertoires

Malaria | Schistosomiasis | Hiv Infection

Uganda
MacroGenics
National Institute of Allergy and Infectious Diseases (NIAID)

No longer available

Expanded Access to MGAWN1 in Subjects With Suspected West Nile Neuroinvasive Disease; Suspected West Nile Virus Infection; or Substantial Accidental Exposure

West Nile Virus Infection

Clinical Trials on Central Nervous System Protozoal Infections

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Congo, DR of

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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