Clinical Trials on Chemotherapeutic Toxicity

Total 703 results

Jessa Hospital

Completed

Antibiotic Prophylaxis in Transurethral Prostate Resection (TURP) and Transurethral Bladder Tumour Resection (TURB) (Prophylaxis001)

Bladder Cancer | Antibiotic-associated Diarrhea | Antibiotic Resistant Infection | Antibiotic Resistant Strain | Antibiotic Toxicity | Prostate Hyperplasia | Urosepsis

Belgium
East and North Hertfordshire NHS Trust
British Acupuncture Council

Unknown

Limiting Chemotherapy Side Effects by Using Moxa

Genital Neoplasms, Female | Breast Neoplasms | Colorectal Neoplasms | Toxicity Due to Chemotherapy

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

Sarcoma | Cardiac Toxicity

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
Jianxing He

Not yet recruiting

Efficacy and Safety of Perioperative Use of Breztri Aerosphere to Relieve Cough After Lobectomy

Cough | Drug Effect | Lung Cancer, Nonsmall Cell | Perioperative | Drug Toxicity
En Chu Kong Hospital

Active, not recruiting

Evaluation of Colchicine and Nonsteroidal Anti-inflammatory Drug Combination Therapy and Renal Function in Gout Patients

Renal Impairment | Gout | Nonsteroidals (NSAIDs)Toxicity | Colchicine Adverse Reaction
Marilyn Dodd
National Cancer Institute (NCI)

Completed

GM-CSF Mouthwash for Preventing and Treating Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Radiation Toxicity | Tongue Cancer | Mucositis Oral

United States
University College, London

Recruiting

Focal Therapy for Prostate Cancer Using HIFU (INDEX)

Urinary Incontinence | Prostate Cancer | Male Erectile Disorder | Therapy-related Toxicity

United Kingdom
Sidney Kimmel Comprehensive Cancer Center at Johns...
Avon Foundation

Terminated

Detection and Prevention of Anthracycline-Related Cardiac Toxicity With Concurrent Simvastatin

Breast Cancer | Stage I Breast Cancer | Stage II Breast Cancer | Stage III Breast Cancer

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

MRI in Detecting Heart Damage in Patients With Cancer Receiving Chemotherapy With Exercise Capacity Addendum

Breast Cancer | Malignant Neoplasm | Cardiac Toxicity

United States
The University of Texas Health Science Center at...

Recruiting

Financial Toxicity and Quality of Life in Patients With TGCT

Testicular Neoplasm

United States
Murdoch Childrens Research Institute
University College Hospital, Ibadan; University of Ibadan; University of Tasmania and other collaborators

Completed

Automated Versus Manual Control Of Oxygen For Preterm Infants On Continuous Positive Airway Pressure In Nigeria

Prematurity | Oxygen Toxicity | Neonatal Respiratory Distress Related Conditions | Neonatal Respiratory Failure

Nigeria
National Institute of Cancerología

Active, not recruiting

Effect of an Anti-inflammatory Diet on Patients With Cervical Cancer

Cervical Cancer | Diet Modification | Pelvic Inflammatory Disease | Radiation Toxicity | Uterine Cervical Neoplasm

Mexico
Grupo Espanol de Investigacion en Sarcomas

Active, not recruiting

Selinexor as Single Agent and With Imatinib in Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (SeliGIST) (SeliGIST)

Drug Use | GIST | Drug Toxicity | Metastatic Adult Soft Tissue Sarcoma | Maximum Tolerated Dose

Spain
Royal Marsden NHS Foundation Trust

Completed

Sargramostim to Prevent Mucositis in Patients Receiving Radiation Therapy for Laryngeal Cancer

Head and Neck Cancer | Radiation Toxicity | Oral Complications

United Kingdom
Prof Gérard WAEBER
Centre Hospitalier Universitaire Vaudois; University of Lausanne; Center for...

Terminated

A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis. (DIAFER)

Iron-deficiency | Safety Issues | Metabolic Disorder, Glucose | Iron Toxicity | Glucose Metabolism Disorders (Including Diabetes Mellitus) | Metabolic Side Effects of Drugs

Switzerland
Xijing Hospital

Unknown

Chemotherapy Combined With Whole-body Hyperthermia to Treat Stage IIIB/IV Non Small Cell Lung Cancer (WBH&NSCLC)

Toxicity Due to Chemotherapy | Non-small Cell Lung Cancer Stage IIIB

China
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

Brain and Central Nervous System Tumors | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United States
University of Southern California
National Cancer Institute (NCI)

Terminated

Questionnaires in Identifying Upper Extremity Function and Quality of Life After Treatment in Patients With Breast Cancer

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Musculoskeletal Complication | Therapy-Related Toxicity

United States
Abramson Cancer Center at Penn Medicine

Enrolling by invitation

Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy (CLARITY)

Cardiotoxicity | Radiation Toxicity | Lung Cancer Stage III | Lung Cancer Stage II

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Donepezil and Vitamin E to Prevent Side Effects Caused By Radiation Therapy to the Head in Patients Receiving Treatment for Small Cell Lung Cancer

Depression | Delirium | Lung Cancer | Radiation Toxicity | Cognitive/Functional Effects

United States
Ohio State University

Not yet recruiting

DIAMOND-Lewy Guidelines for Antipsychotic Use in Older Patients

Movement Disorders | Aging | Behavior | Dementia With Lewy Bodies | Emergency Psychiatric | Cognition Disorder | Antipsychotics and Neuroleptics Toxicity | Alteration in Mental Status
Qilu Hospital of Shandong University

Recruiting

Cardiac Toxicity and Prognostic Value of New Echocardiographic Indicators in the Treatment of Primary Multiple Myeloma

Multiple Myeloma

China
University of California, Los Angeles
Gilead Sciences

Completed

Relative Mitochondrial Toxicity of Tenofovir Alafenamide (TAF) vs. Tenofovir Disoproxil Fumarate (TDF) (UCLACAREMITO)

HIV/AIDS | Mitochondrial Alteration | Antiviral Toxicity | Antiviral Drug Adverse Reaction

United States
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy, Surgery, and Radiation Therapy With or Without Dexrazoxane and Trastuzumab in Treating Women With Stage III or Stage IV Breast Cancer

Inflammatory Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Cardiac Toxicity

United States
University Hospitals Cleveland Medical Center

Completed

Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery

Postoperative Pain | Postpartum Hemorrhage | Blood Loss, Postoperative | Opioid Use | Analgesia, Obstetrical | Coagulation Defect; Postpartum | Nonsteroidals (NSAIDs)Toxicity | Ketorolac Adverse Reaction

United States
University of Kansas Medical Center

Completed

Evaluation of MyoStrain™ in Clinical Practice

Coronary Artery Disease | Amyloidosis | Myocarditis | Sarcoidosis | Lupus | Cardiac Failure | Drug Toxicity

United States
Affiliated Hospital of Qinghai University

Not yet recruiting

Cardiotoxicity of Targeted Therapy for HER-2 Positive Breast Cancer Patients at High Altitude

HER2-positive Breast Cancer | Targeted Therapy | Cardiac Toxicity | High Altitude

China
Beth Israel Deaconess Medical Center
Society for Obstetric Anesthesia and Perinatology

Active, not recruiting

IV Ketorolac on Platelet Function Post-Cesarean Delivery (KetoPltAgg)

Postoperative Pain | Postpartum Hemorrhage | Blood Loss, Postoperative | Analgesia, Obstetrical | Coagulation Defect; Postpartum | Nonsteroidals (NSAIDs)Toxicity | Ketorolac Adverse Reaction

United States
Aarhus University Hospital
Rigshospitalet, Denmark; Herlev Hospital

Recruiting

TDM for Optimized Outcome in Patients With mRCC.

Kidney Cancer | Renal Cell Carcinoma Metastatic | Drug Toxicity | Drug Side Effect | Drug Mechanism

Denmark
Hospitalsenheden Vest
Boehringer Ingelheim; Erasmus Medical Center; University of Aarhus; Catharina Ziekenhuis... and other collaborators

Completed

Adherence and Coagulation Assays in Dabigatran-treated Patients With Atrial Fibrillation (ARCADE)

Thrombosis | Atrial Fibrillation | Bleeding | Medication Adherence | Drug Effect | Anticoagulants; Circulating, Hemorrhagic Disorder | Drug Use | Blood Coagulation Disorder | Laboratory Problem | Drug Toxicity | Blood Clot | Blood Coagulation Tests | Drug Intolerance

Denmark
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's Lymphoma (T-Cell #4)

Lymphoma | Leukemia | Cardiac Toxicity
Abramson Cancer Center at Penn Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Pilot Study of an NTproBNP Guided Strategy of Cardioprotection (NTproBNP-Guide)

Heart Failure | Lymphoma | Breast Cancer | Cardiomyopathies | Cardiotoxicity | Toxicity Due to Chemotherapy

United States
St. James's Hospital, Ireland

Completed

Neoadjuvant Therapy for Esophageal Cancer and Cardiopulmonary Physiology

Pneumonia | Adenocarcinoma | Respiratory Failure | Esophageal Cancer | Pulmonary Fibrosis | Surgery | Chemotherapy Effect | Radiation Toxicity | Squamous Cell Carcinoma | Radiation Pneumonitis | Radiation Fibrosis

Ireland
University of Calgary
The Hospital for Sick Children; CHU de Quebec-Universite Laval; McMaster University and other collaborators

Recruiting

HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers

Radiation Toxicity | Radiation Exposure | DIPG | Brain Tumor, Pediatric, Recurrent | Brain Tumor, Pediatric | Brain Tumor, DIPG

Canada
Massachusetts General Hospital
Dana-Farber Cancer Institute

Recruiting

Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis

Melanoma Stage IV | Melanoma Stage III | Drug Toxicity | Immune-related Adverse Event | Skin Cancer Stage III | Skin Cancer Stage IV | Drug-Induced Colitis

United States
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Withdrawn

Pre Hospital Evaluation of Video Laryngoscopy (EVE)

Shock | Trauma, Nervous System | Cardiac Arrest | Respiratory Distress Syndrome | Drug Toxicity | Acute Post-trauma Stress State
Sun Yat-sen University

Recruiting

Evaluation of Impedance Cardiography for Assessing Hemodynamic Shifts in Patients With LA-NSCLC During Treatment.

Non-small Cell Lung Cancer | Cardiac Toxicity

China
National Cancer Institute (NCI)

Completed

Radiation Therapy, Bevacizumab, Paclitaxel, and Carboplatin in Treating Patients With Unresectable Stage IIIB or Stage IV Non-Small Cell Lung Cancer at High Risk for Hemoptysis Caused by Bevacizumab

Stage IIIB Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Drug/Agent Toxicity by Tissue/Organ | Adenosquamous Cell Lung Cancer | Hemoptysis
Ohio State University Comprehensive Cancer Center

Withdrawn

Pulmonary Rehabilitation in Improving Lung Function in Patients With Locally Advanced Non-Small Cell Lung Cancer Undergoing Chemoradiation

Fatigue | Cachexia | Radiation Toxicity | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Pulmonary Complications | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer
Silesian Centre for Heart Diseases
Medical Research Agency, Poland

Not yet recruiting

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Heart Failure | Breast Cancer | Breast Diseases | Cardiotoxicity | Molecular Mechanisms of Pharmacological Action | Angiotensin Receptor Antagonists | Neoplasm, Breast | Cardiac Toxicity | Angiotensin II Type 1 Receptor Blockers | Cancer, Therapy-Related | Antihypertensive Agents | Sacubitril/Valsartan | Cancer...

Poland
National Cancer Institute (NCI)

Completed

Triapine, Cisplatin, and Radiation Therapy in Treating Patients With Cervical Cancer or Vaginal Cancer

Recurrent Cervical Cancer | Recurrent Vaginal Cancer | Stage IB Cervical Cancer | Stage II Vaginal Cancer | Stage IIA Cervical Cancer | Stage IIB Cervical Cancer | Stage III Cervical Cancer | Stage III Vaginal Cancer | Stage IVA Cervical Cancer | Stage IVA Vaginal Cancer | Stage IVB Cervical Cancer | Stage IVB... and other conditions

United States
University of Alabama at Birmingham
O'Neal Comprehensive Cancer Center at UAB

Active, not recruiting

Interventions to Decrease Financial Toxicity (P-COC)

Cervical Cancer | Vulvar Cancer | Cancer, Breast | Uterine Cancer | Cancer Colorectal | Cancer, Ovarian

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

A Standardized Nursing Intervention Protocol for HCT Patients

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Psychosocial Effects of Cancer and Its Treatment | Myelodysplastic/Myeloproliferative Neoplasms | Therapy-related Toxicity

United States
Medical University of Warsaw

Completed

Liver Function After Intravenous Methylprednisolone Administration

Liver Diseases | Liver Failure | Graves Ophthalmopathy | Graves Disease | Acute Liver Failure | Acute Liver Injury | Liver Dysfunction | Glucocorticoids Toxicity | Liver Injury | Liver Insufficiency | Acute Liver Injury, Drug Induced | Methylprednisolone Adverse Reaction | Dysthyroid Orbitopathy | Dysthyroid Ophthalmopathy
Royal Marsden NHS Foundation Trust

Completed

Low-Fiber Diet or High-Fiber Diet in Preventing Bowel Side Effects in Patients Undergoing Radiation Therapy for Gynecological Cancer, Bladder Cancer, Colorectal Cancer, or Anal Cancer

Sarcoma | Cervical Cancer | Colorectal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Bladder Cancer | Anal Cancer | Radiation Toxicity | Gastrointestinal Complications

United Kingdom
Sanko University

Completed

Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newborns (therapy)

Preterm Birth | Respiratory Distress Syndrome | Bronchopulmonary Dysplasia | Mechanical Ventilation Complication | Chronic Liver Disease | Hyaline Membrane Disease | Premature | Oxygen Toxicity | Neonatal Respiratory Failure | Atelectasis Neonatal | Mechanical Ventilation Pressure High | Pneumonia Neonatal | Lobar...

Turkey
Royal Marsden NHS Foundation Trust

Unknown

Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer

Sarcoma | Cervical Cancer | Testicular Germ Cell Tumor | Colorectal Cancer | Ovarian Cancer | Prostate Cancer | Bladder Cancer | Endometrial Cancer | Radiation Toxicity | Vaginal Cancer | Gastrointestinal Complications | Long-term Effects Secondary to Cancer Therapy in Adults

United Kingdom
Northwell Health

Completed

The CAROLE (CArdiac Related Oncologic Late Effects) Study (CAROLE)

Coronary Artery Disease | Lymphoma | Cancer | Breast Cancer | Lung Cancer | Cardiotoxicity | Cardiac Disease | Carcinoma, Intraductal, Noninfiltrating | Cardiac Toxicity | Radiation | Radiation Therapy | Atherosclerotic Heart Disease

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Epoetin Alfa in Treating Anemia in Patients Who Are Receiving Chemotherapy

Lymphoma | Leukemia | Breast Cancer | Chronic Myeloproliferative Disorders | Anemia | Small Intestine Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Immunologic Diagnostic Blood Test in Predicting Side-Effects in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Other Diseases

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Myelodysplastic-Myeloproliferative Diseases | Neuroblastoma | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease | Therapy-related Toxicity

United States

Clinical Trials on Chemotherapeutic Toxicity

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Djibouti

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Rare Diseases

Drug Interventions

Dietary Supplements

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