Clinical Trials on Cholestasis, Intrahepatic

Total 688 results

National Cancer Institute (NCI)

Completed

Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors

Epithelioid Mesothelioma | Cholangiocarcinoma, Extrahepatic | Neoplasms With Mesothelin Expression | Adenocarcinoma, Pancreatic

United States
Asian Institute of Gastroenterology, India

Unknown

Role of Endoscopic RFA in Prolonging the Patency of Metal Stents in Patients With Malignant Obstructive Jaundice

Jaundice Extrahepatic Obstructive | Disorder of Bile Duct Stent

India
Nicole Hildebrand
RWTH Aachen University

Recruiting

FGF19 in Obstructive Cholestasis: "Unveil the Signal" (FOCUS)

Pancreatic Neoplasms | Cholangiocarcinoma | Cholestasis | Liver Metastasis Colon Cancer | Icterus

Germany
University Hospital, Linkoeping

Completed

Biliary Metal Stent Study: Metal Stents for Management of Distal Malignant Biliary Obstruction

Pancreatic Cancer | Bile Duct Cancer | Gallbladder Cancer | Bile Duct Obstruction

Sweden
Zhejiang Hisun Pharmaceutical Co. Ltd.

Unknown

Efficacy and Safety of S-adenosyl-L-methionine in Treatment of Chronic Hepatitis B Patients With Cholestasis

Hepatitis B | Cholestasis

China
Zhejiang Hisun Pharmaceutical Co. Ltd.

Unknown

Efficacy and Safety of S-adenosyl-l-methionine in Treatment of Alcoholic Hepatitis With Cholestasis

Hepatitis, Alcoholic

China
University of Pittsburgh

Suspended

Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study (GREAT1)

Multiple Sclerosis | Diabetes Mellitus | Chronic Kidney Diseases | Gastritis | Rheumatoid Arthritis | Chronic Pain | Irritable Bowel Syndrome | Hepatitis | Inflammatory Bowel Diseases | Dyslipidemias | Chronic Disease | Celiac Disease | Cholecystitis | Crohn Disease | Cystic Fibrosis | Chronic Pancreatitis | NASH - Nonalcoholic... and other conditions

United States
University of Washington
National Cancer Institute (NCI); The Safeway Foundation

Active, not recruiting

Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer

Digestive System Carcinoma | Gastric Carcinoma | Colon Carcinoma | Esophageal Carcinoma | Liver and Intrahepatic Bile Duct Carcinoma | Pancreatic Carcinoma | Rectal Carcinoma | Pancreatic Neuroendocrine Tumor | Anal Carcinoma | Malignant Digestive System Neoplasm | Appendix Carcinoma | Small Intestinal Carcinoma and other conditions

United States
University of Miami

Terminated

Prevention of Parenteral Nutrition-Associated Cholestasis With Cyclic Parenteral Nutrition in Infants

Necrotizing Enterocolitis | Cholestasis | Gastroschisis | Intestinal Atresia | Prematurity

United States
First People's Hospital of Hangzhou

Recruiting

Safety and Efficacy of PDT vs RFA vs PDT+RFA for the Treatment of Extrahepatic Cholangiocarcinoma

Bile Duct Cancer | Extrahepatic Cholangiocarcinoma

China
Sun Yat-sen University

Active, not recruiting

Adjuvant Immunotherapy Combined With Chemoradiation for Patients With High-risk reseCtable Extrahepatic chOlangiocaRcinoma and gallblaDder Cancer (ACCORD)

Biliary Tract Cancer | Gallbladder Cancer | Extrahepatic Cholangiocarcinoma

China
M.D. Anderson Cancer Center

Recruiting

Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy

Metastatic Malignant Neoplasm in the Liver | Primary Malignant Liver Neoplasm | Liver and Intrahepatic Bile Duct Neoplasm

United States
University of Washington

Recruiting

Sulfur Colloid SPECT/CT in Measuring Liver Function in Patients With Primary or Metastatic Liver Cancer Undergoing Radiation Therapy or Surgery

Hepatocellular Carcinoma | Intrahepatic Cholangiocarcinoma | Stage IV Liver Cancer | Stage IVA Liver Cancer | Stage IVB Liver Cancer | Vascular Thrombosis

United States
Fox Chase Cancer Center

Completed

PET-CT in Determining the Radioembolization Dose Delivered to Patients With Liver Metastasis, Primary Liver Cancer, or Biliary Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Advanced Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Adult Primary Hepatocellular Carcinoma | Metastatic Extrahepatic Bile Duct Cancer | Stage D Adult Primary Liver Cancer (BCLC)

United States
Xi'An Aolitai Pharmaceutical Technology Co Ltd

Recruiting

A Randomized,Double-blind, Placebo Controlled, Multicenter Study to Evaluate the Safety and Efficacy of MT2004 Capsule in DILI Subjects

Drug-Induced Liver Injury | Cholestatic Liver Injury | Mixed Liver Injury

China
Washington University School of Medicine

Completed

Diagnosis of Bile Duct Strictures

Pancreatic Cancer | Cholangiocarcinoma | Chronic Pancreatitis | Bile Duct Stricture

United States
Shanghai Jiao Tong University School of Medicine
RenJi Hospital; Huashan Hospital; Ruijin Hospital; Eastern Hepatobiliary Surgery... and other collaborators

Unknown

Molecularly Target Therapy With FORFIRINOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma

Gallbladder Cancer | Cholangiocarcinoma of the Extrahepatic Bile Duct

China
Michael J Cavnar, MD

Terminated

Codman Catheter/Synchromed Pump Hepatic Artery Chemotherapy for Unresectable Colorectal Metastases/Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Bile Duct Neoplasms

United States
Shanghai Jiao Tong University School of Medicine
RenJi Hospital; Huashan Hospital; Ruijin Hospital; Eastern Hepatobiliary Surgery...

Unknown

Chemothetapy FORFIRINOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma

Gallbladder Cancer | Cholangiocarcinoma of the Extrahepatic Bile Duct

China
Shanghai Jiao Tong University School of Medicine
RenJi Hospital; Huashan Hospital; Ruijin Hospital; Eastern Hepatobiliary Surgery... and other collaborators

Unknown

Molecularly Target Therapy With GEMOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma

Gallbladder Cancer | Cholangiocarcinoma of the Extrahepatic Bile Duct

China
National Cancer Institute (NCI)

Completed

Lapatinib in Treating Patients With Locally Advanced or Metastatic Biliary Tract or Liver Cancer That Cannot Be Removed By Surgery

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Adult Primary Hepatocellular...

United States
National Cancer Institute (NCI)

Completed

Lapatinib Ditosylate in Treating Patients With Unresectable Liver or Biliary Tract Cancer

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Adult Primary Hepatocellular...

United States
Clinical Hospital Colentina
Catholic University, Italy

Completed

EUS Evaluation of CBD Diameter in Malignant Obstructive Jaundice (ECCO)

Pancreatic Cancer | Jaundice, Obstructive | Cholangiocarcinoma of the Extrahepatic Bile Duct | Ampulla of Vater Cancer

Romania
Peking University Third Hospital
Beijing Tsinghua Changgeng Hospital

Recruiting

Evaluation of diagnostiC Capacity of eccDNAs as Biomarkers in Indetermined biLiary Stricture(ECCBILE) (ECCBILE)

Bile Duct Cancer | Pancreas Cancer | Biliary Stricture

China
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0809: Capecitabine, Gemcitabine, and RT in Patients w/Cholangiocarcinoma of the Gallbladder or Bile Duct

Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Memorial Sloan Kettering Cancer Center
Bayer

Completed

Gemcitabine and Cisplatin Plus Sorafenib in Patients With Advanced Biliary Tract Carcinomas Naive to Systemic Therapy

Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
University Hospital Plymouth NHS Trust
University of Plymouth

Completed

Recurrence After Whipple's (RAW) Study

Pancreatic Cancer | Surgery | Bile Duct Cancer | Pancreatic Ductal Adenocarcinoma | Survivorship | Cholangiocarcinoma, Extrahepatic | Cancer Recurrence | Recurrent Cancer | Pancreatic Ductal Carcinoma | Cholangiocarcinoma of the Extrahepatic Bile Duct | Ampullary Cancer | Cholangiocarcinoma Resectable | Cancer... and other conditions

Spain, United Kingdom, Australia, Austria, Italy, Mexico, Sudan, Pakistan
Weill Medical College of Cornell University

Unknown

Radio Frequency Ablation in the Management of Pancreatico-biliary Disorders: A Multicenter Registry (RFA-Registry)

Pancreatic Cancer | Cholangiocarcinoma | Bile Duct Cancer | Biliary Stricture | Bile Duct Obstruction

United States
Mayo Clinic

Completed

Intravital Microscopy in Human Solid Tumors

Malignant Solid Neoplasm | Gastric Carcinoma | Solid Tumor, Adult | Clinical Stage IV Gastric Cancer AJCC v8 | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Metastatic Gastric Carcinoma | Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8 | Metastatic Sarcoma | Resectable... and other conditions

United States
UNICANCER

Completed

Gemcitabine Hydrochloride and Oxaliplatin or Observation in Treating Patients With Biliary Tract Cancer That Has Been Removed by Surgery

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

France
University College, London

Completed

Biliary Stenting With or Without Photodynamic Therapy in Treating Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma or Other Biliary Tract Tumors That Cannot Be Removed by Surgery (Photostent-02)

Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United Kingdom
European Organisation for Research and Treatment...

Terminated

Radiation Therapy and Fluorouracil Before Surgery in Treating Patients With Primary or Recurrent Bile Duct Cancer

Liver Cancer | Extrahepatic Bile Duct Cancer

France, United States, Belgium
Roswell Park Cancer Institute

Completed

Gemcitabine and Capecitabine in Treating Patients With Advanced and/or Inoperable Cholangiocarcinoma or Carcinoma of the Gallbladder

Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0202 Gemcitabine and Capecitabine for Unresectable Locally Advanced Metastatic Gallbladder Cancer or Cholangiocarcinoma

Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
University College, London
Eli Lilly and Company

Completed

Gemcitabine With or Without Cisplatin in Treating Patients With Unresectable Locally Advanced or Metastatic Cholangiocarcinoma or Other Biliary Tract Tumors (ABC-02)

Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United Kingdom
NCIC Clinical Trials Group

Terminated

Gemcitabine With/Out Capecitabine in Locally Advanced, Unresectable, or Metastatic Biliary Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

Canada
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Gemcitabine Plus Pemetrexed Disodium in Treating Patients With Unresectable or Metastatic Biliary Tract or Gallbladder Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Rebeccamycin Analogue in Treating Patients With Advanced Liver and/or Biliary Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Federation Francophone de Cancerologie Digestive

Completed

Fluorouracil, Cisplatin, and Radiation Therapy or Gemcitabine and Oxaliplatin in Treating Patients With Nonmetastatic Biliary Tract Cancer That Cannot Be Removed By Surgery

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

France
Daiichi Sankyo, Inc.

Completed

DX-8951f in Treating Patients With Biliary Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Dolastatin 10 in Treating Patients With Metastatic Or Recurrent Liver, Bile Duct, or Gallbladder Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Brown University

Unknown

Liposomal Doxorubicin in Treating Patients With Liver or Bile Duct Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
University Hospital Southampton NHS Foundation...

Completed

Capecitabine or Observation After Surgery in Treating Patients With Biliary Tract Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United Kingdom
Ruijin Hospital
Intuitive Surgical

Recruiting

Robotic Versus Open Pancreaticoduodenectomy for Pancreatic and Periampullary Tumors (PORTAL)

Pancreatic Adenocarcinoma | Chronic Pancreatitis | Ampullary Adenocarcinoma | Cholangiocarcinoma, Extrahepatic | Pancreatic Cysts | Pancreatic Endocrine Tumors | Duodenal Adenocarcinoma

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Unresectable or Metastatic Biliary Tract or Gallbladder Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Blood Proteins in Finding Pancreatic Cancer and Extrahepatic Biliary Tract Cancer

Pancreatic Cancer | Extrahepatic Bile Duct Cancer
Celgene
Celgene Corporation

Completed

Study of Orally Administered Enasidenib (AG-221) in Adults With Advanced Solid Tumors, Including Glioma, or Angioimmunoblastic T-cell Lymphoma, With an IDH2 Mutation

Glioma | Solid Tumor | Angioimmunoblastic T-cell Lymphoma | Chondrosarcoma | Intrahepatic Cholangiocarcinoma

United States, France
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract Cancer

Intrahepatic Cholangiocarcinoma | Hilar Cholangiocarcinoma | Distal Cholangiocarcinoma | Gall Bladder Carcinoma | Biliary Tract Cancer (CCA)

Germany
Swiss Group for Clinical Cancer Research

Completed

Adjuvant Palliative Capecitabine and Gemcitabine in Treating Patients With Locally Advanced or Metastatic Biliary Tract Cancer

Pain | Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

Switzerland
University of Pittsburgh
National Cancer Institute (NCI)

Completed

Radiation Therapy in Treating Patients With Bile Duct, Gallbladder, or Pancreatic Cancer

Pancreatic Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States

Clinical Trials on Cholestasis, Intrahepatic

Sponsors and Collaborators

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CROs in Liberia

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