Clinical Trials on Cholesterol Metabolism

Total 54435 results

University of Pennsylvania

Suspended

Mendelian Reverse Cholesterol Transport Study

Lipid Metabolism, Inborn Errors | Cholesterol, HDL | Tangier Disease | LCAT Deficiency | Cholesteryl Ester Transfer Protein (CETP) Deficiency

United States
ProgenaBiome

Recruiting

A Pilot Study to Explore the Role of Gut Flora in Elevated Cholesterol

Cholesterol, Elevated | Elevated Cholesterol

United States
Novo Nordisk A/S

Completed

A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation II

Healthy Volunteers; High Cholesterol

United States
Unilever R&D

Completed

Efficacy Study on the Lipid-lowering Effect of Plant Sterols and Fish Oil

Healthy | Mildly Elevated Cholesterol Levels

Sweden
Oslo University Hospital
Mills DA

Completed

The Effect of Plant Sterol Supplement on Blood Cholesterol

High Blood Cholesterol Level

Norway
PepsiCo Global R&D

Completed

The Effect of Oats Containing 1.4g Beta Glucan on Fecal Bacterial Population(s) and Plasma Cholesterol in Healthy Adults With Elevated Cholesterol Levels

Microbiome | Plasma Cholesterol | Prebiotic

Ireland
Maastricht University Medical Center
ezCOL B.V.

Completed

Rhodospirillum Rubrum and Cholesterol

Cholesterol Metabolism

Netherlands
Ankara University
Alexion Pharmaceuticals

Completed

National Lysosomal Acid Lipase Deficiency Study (LAL-D)

Cholesteryl Ester Storage Disease

Turkey
Children's Hospital Medical Center, Cincinnati
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Wolman/CESD Natural History Chart Review and Longitudinal Follow-Up

Wolman Disease | Cholesterol Ester Storage Disease | Acid Cholesteryl Ester Hydrolase Deficiency, Type 2

United States
Touro University, California

Completed

Investigating the Production of Lipoproteins and Acetyl-CoA During a Ketogenic Diet (PLAK)

Cholesterol Metabolism | Ketone Metabolism

United States
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Wolman Disease (BioWolman) (BioWolman)

Cholesterol Ester Storage Disease | Acid Lipase Deficiency | Acid Cholesteryl Ester Hydrolase Deficiency, Wolman Type

Germany, India, Sri Lanka
Cliniques universitaires Saint-Luc- Université...

Withdrawn

Functional and Clinical Impact of CYP3A Genetic Polymorphisms on Statin Therapy

Patients With High Cholesterol Levels Needing a Lipid-lowering Therapy

Belgium
Arizona State University
North American Millers Association - Corn Division

Completed

Corn and Heart Health Study (CHS)

Gut Microbiome | Cholesterol, LDL | Cholesterol, HDL

United States
Novartis Pharmaceuticals

Completed

Safety, Pharmacokinetics and Pharmacodynamics of LGT209 in Healthy Volunteers With Elevated Cholesterol and in Hypercholesterolemic Patients Treated With Statins

Hypercholesterolemia | LDL Cholesterol

United States
AstraZeneca
The Cleveland Clinic; Concentrics Research LLC; Concentrics Research - STATKING... and other collaborators

Completed

Technology-Assisted Cholesterol Trial in Consumers (TACTiC) (TACTiC)

High Cholesterol

United States
Alexion

Recruiting

Lysosomal Acid Lipase (LAL) Deficiency Registry (ALX-LALD-501)

Wolman Disease | Cholesterol Ester Storage Disease | Lysosomal Acid Lipase Deficiency | Acid Cholesteryl Ester Hydrolase Deficiency, Type 2 | Acid Lipase Deficiency | LIPA Deficiency | LAL-Deficiency

France, Belgium, United States, Spain, Germany, Greece, Israel, Italy, Slovenia, United Kingdom, Brazil, Canada, Denmark, Australia, Croatia, Czechia, Ireland, Mexico, Netherlands, Poland, Portugal, Saudi Arabia
Skogli Health and Rehabilitation Center

Completed

Effects of a Single Dose of Brazil Nuts on Blood Lipids

Cholesterol Level, High

Norway
AstraZeneca

Completed

An Observational Study Evaluating Cholesterol Levels in Patients on Cholesterol Lowering Drugs in Jordan and Lebanon (CEPHEUS)

High Blood Cholesterol
Integrative Health Technologies, Inc.

Unknown

Study of Changes in Total Cholesterol Levels as a Function of Consuming a Supplement Designed to Improve Cardiovascular Health (AdBiotech)

Hyperlipidemia | Hypercholesteremia | Cholesterol

United States
Laval University
Université de Montréal; Centre de Recheche du Centre Hospitalier Université...

Recruiting

Unravelling the Impact of Diet on Cardiovascular Health in Heterozygous Familial Hypercholesterolemia. (FH-Diet)

Cardiovascular Diseases | Familial Hypercholesterolemia | Cholesterol, Elevated | Nutrition, Healthy | Cholesterol; Metabolic Disorder

Canada
Massachusetts General Hospital
Center for Survey Research, University of Massachusetts, Boston

Completed

Online Trial Examining Validity of the Shared Decision Making Process Survey With Video Vignettes

Colorectal Cancer | High Cholesterol

United States
James Backes, PharmD
Marcor Development Corporation

Completed

Effect of Policosanol as Monotherapy and Adjunctive to Statin Therapy

High Cholesterol

United States
Instituto Aragones de Ciencias de la Salud

Completed

Effect of Different Fat Enriched Meats on the Hepatic Cholesterol Synthesis

Lipid Metabolism Disorders | Hyperlipidemias | Diet, High-Fat | Cholesterol | Fatty Acids | Sterols
Yonsei University

Completed

Comparison of Fenofibrate and Niacin in Patients With Hypertriglyceridemia and Low High-Density Lipoprotein (HDL)-Cholesterol

Hypertriglyceridemia With Low HDL-cholesterol
University of Bergen
The Norwegian Seafood Research Fund

Not yet recruiting

Effect of Herring Oil Concentrate on LDL Cholesterol Concentration in Adults

High Cholesterol

Norway
University of Aarhus
TrygFonden, Denmark

Completed

The RISAP-study: a Complex Intervention in Risk Communication and Shared Decision-making in General Practice (RISAP)

Cardiovascular Disease | High Cholesterol
Gachon University Gil Medical Center

Completed

Additive Effects of Pravastatin and Valsartan

Hypertension | High Cholesterol

Korea, Republic of
NewAmsterdam Pharma

Completed

Randomized Study of Obicetrapib in Combination With Ezetimibe (OCEAN)

Dyslipidemias | Hypercholesterolemia | High Cholesterol

United States, Netherlands
Texas A&M University

Completed

Impact of Beef's Unique Food Matrix on Human Health

Cholesterol, LDL | Cholesterol, HDL | Research Subjects

United States
NewAmsterdam Pharma

Completed

A Dose-Finding Study in Japanese Patients to Evaluate the Effect of Obicetrapib as an Adjunct to Stable Statin Therapy.

Dyslipidemia | Hypercholesterolemia | High Cholesterol

Japan
NewAmsterdam Pharma

Completed

Study to Evaluate the Effect of Obicetrapib in Combination With Ezetimibe as an Adjunct to HIS Therapy (ROSE2)

Dyslipidemias | Hypercholesterolemia | High Cholesterol

United States
NewAmsterdam Pharma

Completed

Randomized Study of Obicetrapib as an Adjunct to Statin Therapy (ROSE)

Dyslipidemias | Hypercholesterolemia | High Cholesterol

United States
Universidad Miguel Hernandez de Elche

Unknown

Effects on Lipid Metabolism of Olive Extracts Rich in Polyphenols

Metabolic Syndrome | Cholesterol; Metabolic Disorder

Spain
Alexion Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of SBC-102 (Sebelipase Alfa) in Adult Participants With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency | Cholesterol Ester Storage Disease(CESD) | LAL-Deficiency

France, United States, United Kingdom, Czechia
Alexion Pharmaceuticals

Completed

Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of SBC-102 (Sebelipase Alfa) in Adult Subjects With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency | LAL-Deficiency | Cholesterol Ester Storage Disease (CESD)

France, United Kingdom, United States, Canada, Czechia
Jeff Golini
All American Pharmaceutical

Terminated

Observational Study of Lyzme5 Impact on Cholesterol and Body Weight in Man (Lyzme5)

Overweight | Elevated Cholesterol

United States
Alexion Pharmaceuticals

Completed

An Observational Study of Patients With Lysosomal Acid Lipase Deficiency/Cholesteryl Ester Storage Disease Phenotype

Lysosomal Acid Lipase Deficiency | Cholesterol Ester Storage Disease(CESD)

United States, United Kingdom, France, Canada, Czech Republic, Italy, Poland, Switzerland
The Medicines Company

Completed

Inclisiran for Subjects With ASCVD or ASCVD-Risk Equivalents and Elevated Low-density Lipoprotein Cholesterol (ORION-11)

Risk Factor, Cardiovascular | Elevated Cholesterol | ASCVD

Germany, Czechia, Hungary, Poland, South Africa, Ukraine, United Kingdom
University of Turku
University of Eastern Finland

Active, not recruiting

OAT-GUT-BRAIN: Effects of Oats and Rice on Comprehensive Health of Metabolically Challenged Individuals

Overweight and Obesity | High Blood Pressure | High Cholesterol/Hyperlipidemia

Finland
PepsiCo Global R&D
Glycemic Index Laboratories, Inc

Completed

Oat and Cholesterol

Elevated LDL Cholesterol

Canada
Nordic Pharma, USA
Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

Completed

Safety and Efficacy of a Natural Health Product in Reducing Cholesterol and Triglyceride Levels.

Triglycerides | LDL Cholesterol

Canada
University of Oklahoma
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Community Intervention to Improve CVD Risk Factor Control in Young American Indians (CIRCLE)

Diabetes Mellitus | Cholesterol, Elevated
Monash University Malaysia

Recruiting

Can Mindful Eating Improve Cholesterol and Glucose Level

Cholesterol; Lipidosis

Malaysia
Nantes University Hospital
Centre de Recherche en Nutrition Humaine Ouest (CRNH)

Completed

Kinetic Study of Lp(a) and PCSK9 in Humans (HuLaUP)

Cholesterol; Metabolic Disorder | Lipoproteinemia

France
Mitsukoshi Health and Welfare Foundation
Daiichi Sankyo Co., Ltd.; Ministry of Health, Labour and Welfare, Japan

Completed

Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese(MEGA Study)

Hyperlipidemia
Northwestern University
Agency for Healthcare Research and Quality (AHRQ)

Completed

Reducing Disparities in Primary Prevention of Cardiovascular Disease

Cardiovascular Diseases | Cholesterol, LDL

United States
Ayub Teaching Hospital
Khyber Medical University Peshawar

Completed

Effect of Amlodipine on the Lipid Profile of Newly Diagnosed Hypertensive Patients

Hypertension | Hypercholesterolemia | Cholesterol Deposition
Universidad Católica San Antonio de Murcia

Completed

Clinical Trial to Evaluate the Reduction of Cardiovascular Risk (NUT)

Cholesterol

Spain
Organon and Co
Schering-Plough

Completed

MD Ezetimibe Cyclosporine Interaction (0653-057)

Cholesterol
Organon and Co
Schering-Plough

Completed

A Research Study to Evaluate MK0653 (Ezetimibe) and Simvastatin, Given Together and Alone, on Intestinal Absorption of Cholesterol (0653-050)(COMPLETED)

Cholesterol

Clinical Trials on Cholesterol Metabolism

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