Clinical Trials on Choroidal Neo-Vascular Age-onset Macular Degeneration

Total 2578 results

Novartis Pharmaceuticals

Terminated

The Efficacy of Oral Everolimus in Patients With Neovascular Age-related Macular Degeneration

Age-related Macular Degeneration | Choroidal Neo-Vascular Age-onset Macular Degeneration

United Kingdom, United States
Kim's Eye Hospital

Completed

Outcomes of Tolerating Subretinal Fluid in Type 1 MNV and PCV

Age-Related Macular Degeneration | Choroidal Neovascularization | Polypoidal Choroidal Vasculopathy

Korea, Republic of
Medical University of Vienna

Withdrawn

Does Vascular Endothelial Growth Factor (VEGF) or Complement Factor H Gene Polymorphism Play a Role in the Treatment Success With VEGF Inhibitors in Patients With Choroidal NeoVascularization (CNV)?

Age-Related Macular Degeneration | Choroidal NeoVascularization

Austria
University of Utah
National Eye Institute (NEI)

Recruiting

Impact of Non-Exudative Type 1 MNV on AMD Progression

Age-Related Macular Degeneration | Neovascularization, Choroidal

United States
Medical University of Vienna

Completed

Comparison of Ranibizumab Monotherapy and Ranibizumab Combination Therapies in Recurrent or Persistent Choroidal Neovascularization Secondary to Age-related Macular Degeneration

Age-Related Macular Degeneration | Neovascularization, Choroidal

Austria
Xun Xu
Peking University; Zhongshan Ophthalmic Center, Sun Yat-sen University; Air Force... and other collaborators

Unknown

Pharmacogenomic Study on Anti-VEGF Medicine in Treatment of Macular Neovascular Diseases

Age-Related Macular Degeneration | Polypoidal Choroidal Vasculopathy | Pathological Myopia | Conbercept | Pharmacogenomic

China
Allergan

Terminated

A Study Using Intravitreal Injections of a Small Interfering RNA in Patients With Age-Related Macular Degeneration

Age-Related Macular Degeneration | Choroid Neovascularization

United States, Australia, Philippines
Pfizer

Terminated

A Study Of Early Markers Of Choroidal Neovascularization

Age-related Macular Degeneration (AMD) | Choroidal Neovascularization (CNV) | Early Markers

Italy, Portugal, United Kingdom
Genentech, Inc.

Completed

An Extension Study to Evaluate the Safety and Tolerability of Ranibizumab in Subjects With Choroidal Neovascularization Secondary to AMD or Macular Edema Secondary to RVO

Choroidal Neovascularization, Age-related Macular Degeneration
Salutaris Medical Devices, Inc.

Not yet recruiting

Adjunct Episcleral Brachytherapy for PCV (KILAUEA)

Age-Related Macular Degeneration | Polypoid Choroidal Vasculopathy
Singapore National Eye Centre
Bayer

Completed

An Open Label-study to Compare the Efficacy of Aflibercept Monotherapy for Polypoidal Choroidal Vasculopathy

Age Related Macular Degeneration | Polypoidal Choroidal Vasculopathy

Singapore
Alcon Research

Completed

Efficacy and Safety of RTH258 Versus Aflibercept - Study 2 (HARRIER)

Choroidal Neovascularization | Neovascular Age-Related Macular Degeneration
Alcon Research

Completed

Efficacy and Safety of RTH258 Versus Aflibercept - Study 1 (HAWK)

Choroidal Neovascularization | Neovascular Age-Related Macular Degeneration

United States
Pusan National University Hospital
Bayer

Completed

Effect of Intravitreal VEGF-Trap Eye on Polypoidal Choroidal Vasculopathy (VAULT)

Polypoidal Choroidal Vasculopathy | Exudative Age-related Macular Degeneration

Korea, Republic of
Novartis Pharmaceuticals

Completed

Comparison of Treatment Regimens Using Ranibizumab: Intensive (Resolution of Intra- and Sub-retinal Fluid) vs Relaxed (Resolution of Intra-retinal Fluid and/or Sub-retinal Fluid >200µm at the Foveal Centre) (FLUID)

Subfoveal Choroidal Neovascularization CNV Secondary to Wet Age-related Macular Degeneration AMD

Australia
Quark Pharmaceuticals
Pfizer

Completed

Phase II Open Label Multicenter Study For Age Related Macular Degeneration Comparing PF-04523655 Versus Lucentis In The Treatment Of Subjects With CNV (MONET Study). (MONET)

Age Related Macular Degeneration

Spain, Korea, Republic of, Turkey, Taiwan, United States, Israel, Austria, Philippines, Denmark, Hong Kong, India
AbbVie
AbbVie

Recruiting

RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Neovascular Age-Related Macular Degeneration (nAMD) (AAVIATE)

Neovascular Age-Related Macular Degeneration (nAMD)

United States
Chengdu Kanghong Biotech Co., Ltd.
University of Wisconsin, Madison; Air Force Military Medical University, China

Completed

A Study Assessing the Safety and Efficacy of Multiple Intravitreal KH902 in Patients With CNV Due to AMD (HOPE)

Neovascular Age-related Macular Degeneration

China
Vista Klinik

Completed

SD-OCT-guided Intravitreal Ranibizumab Treatment in Choroidal Neovascularization Due to Myopia

Age Related Macular Degeneration | Choroidal Neovascularization

Switzerland
Vista Klinik

Completed

Time Course of Activity Signs at SD-OCT High Frequency Intravitreal Ranibizumab Treatment in CNV Due to AMD

Age Related Macular Degeneration | Choroidal Neovascularization

Switzerland
Notal Vision Ltd.

Completed

PreView PHP Preferential Hyperacuity Perimeter for the Detection of Choroidal Neovascularization

Age Related Macular Degeneration

Israel
The Ludwig Boltzmann Institute of Retinology and...

Unknown

Stratus Versus Cirrus OCT in AMD

Age-Related Macular Degeneration | Choroidal Neovascularization

Austria
Novartis
QLT Inc.

Completed

Photodynamic Therapy in Occult-Only Lesions (POOL)

Age-Related Macular Degeneration

Switzerland
Johns Hopkins University
Oregon Health and Science University

Completed

Neovascular Age Related Macular Degeneration (AMD), Periocular Corticosteroids, and Photodynamic Therapy (PDT)

Age-Related Macular Degeneration | Choroidal Neovascularization

United States
Michael Abramoff
National Eye Institute (NEI)

Completed

Retinal Therapy Guided by 3D OCT Image Analysis

Age-Related Macular Degeneration | Choroidal Neovascularization

United States
Pusan National University Hospital
Novartis

Completed

Indocyanine Angiographic Changes of Choroidal Neovascularization by Ranibizumab

Exudative Age-related Macular Degeneration

Korea, Republic of
Notal Vision Ltd.

Completed

Home Vision Monitoring Using the ForeseeHome Device Following Treatment of Neovascular Age Related Macular Degeneration (CNV)

Age Related Macular Degeneration | Choroidal Neovascularization

United States
Pfizer

Terminated

A Study Of The Safety And Efficacy Of AG-013,958 In Subjects With Subfoveal Choroidal Neovascularization Associated With Age-Related Macular Degeneration

Age-Related Macular Degeneration

United States, United Kingdom, Australia, Netherlands
Notal Vision Ltd.

Completed

PHP Home Preferential Hyperacuity Perimeter for the Detection of Choroidal Neovascularization (CNV)

Age Related Macular Degeneration

Israel
National Eye Institute (NEI)

Completed

Infliximab, Sirolimus and Daclizumab to Treat Age-Related Macular Degeneration (AMDB1)

Age-Related Macular Degeneration | Choroidal Neovascularization

United States
Notal Vision Ltd.

Withdrawn

Comparison Between Home Macular Perimeter and Optical Coherence Tomography (OCT) Visual Field Defects in Patients With Choroidal Neovascularization (CNV)

Age Related Macular Degeneration | Choroidal Neovascularization

France
Asociación para Evitar la Ceguera en México

Unknown

Efficacy of Retreatments With Intravitreal Bevacizumab

Age Related Macular Degeneration | Choroidal Neovascularization

Mexico
Outlook Therapeutics, Inc.

Completed

A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Age-related Macular Degeneration | Wet Macular Degeneration | Neovascular Age-related Macular Degeneration

United States
Hoffmann-La Roche

Completed

Study to Evaluate Faricimab (RO6867461; RG7716) for Extended Durability in the Treatment of Neovascular Age Related Macular Degeneration (STAIRWAY)

Macular Degeneration, Age-Related | Neovascularization, Choroidal

United States
Outlook Therapeutics, Inc.

Completed

A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Age-related Macular Degeneration | Wet Macular Degeneration | Neovascular Age-related Macular Degeneration

Australia
Chengdu Kanghong Biotech Co., Ltd.
University of Wisconsin, Madison

Completed

A Randomized, Double-masked, Multicenter,Sham-controlled, Safety and Efficacy Study of KH902 in Patients With Wet AMD (PHOENIX)

Neovascular Age-related Macular Degeneration

China
Novartis

Completed

Efficacy and Safety of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD) (EXCITE)

Age Related Macular Degeneration

Switzerland
University Hospital, Basel, Switzerland

Completed

Study Comparing Ranibizumab Monotherapy With Combined Verteporfin Therapy in Subfoveal CNV

Age-Related Macular Degeneration | Choroidal Neovascularization

Switzerland
Santen Inc.
MacuSight, Inc.

Terminated

Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular Degeneration (EMERALD)

Age-Related Macular Degeneration | Choroidal Neovascularization

United States
Novartis

Completed

SUSTAIN - Study of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration

Age Related Macular Degeneration | Choroidal Neovascularization

Switzerland
Allergan
Sirna Therapeutics Inc.

Completed

A Dose Escalation Trial of an Intravitreal Injection of Sirna-027 in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)

Age-Related Macular Degeneration | Choroidal Neovascularization

United States
Novartis

Completed

EXTEND III - Efficacy and Safety of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)

Age-Related Macular Degeneration | Choroidal Neovascularization

Taiwan, Korea, Republic of
Lpath, Inc.

Completed

Efficacy and Safety Study of iSONEP With & Without Lucentis/Avastin/Eylea to Treat Wet AMD (Nexus)

Exudative Age-related Macular Degeneration

United States
Quark Pharmaceuticals
Pfizer

Completed

Study of PF-04523655 (REDD14NP) In Subjects With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (Wet AMD)

Age-Related Macular Degeneration

United States, Israel
Hospital Universitari Vall d'Hebron Research Institute

Completed

Intravitreal Adalimumab in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration

Age-Related Macular Degeneration | Choroidal Neovascularization

Spain
Johns Hopkins University

Completed

Bevicizumab (Avastin) Infusion for Choroidal Neovascularization (CNV) Not Associated With Age-Related Macular Degeneration (AMD)

Choroidal Neovascularization | Pathological Myopia | Degenerative Myopia
Novartis

Completed

Safety and Tolerability of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-related Macular Degeneration

Subfoveal Choroidal Neovascularization (CNV) | Secondary to Age-related Macular Degeneration (AMD)

Germany, Belgium, Spain, Netherlands, United Kingdom, Hungary, Turkey, Israel, Portugal, Australia
Novartis

Completed

Safety and Efficacy of Ranibizumab in Japanese Patients With Subfoveal Choroidal Neovascularization Secondary to Age-related Macular Degeneration

Subfoveal Choroidal Neovascularization(CNV) Secondary to Age-related Macular Degeneration (AMD)

Japan
Novartis

Completed

Safety and Efficacy of Oral PTK787 in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration (AMD) (ADVANCE)

Wet Age-Related Macular Degeneration

Australia, United States
Novartis

Completed

Study of Ranibizumab Administered in Conjunction With Photodynamic Therapy With Verteporfin in Patients With Subfoveal Choroidal Neovascularization and Age-Related Macular Degeneration

Age-Related Macular Degeneration (ARMD)

Switzerland

Clinical Trials on Choroidal Neo-Vascular Age-onset Macular Degeneration

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