Clinical Trials on Chronic Nonspecific Low Back Pain in South Africa

Total 179 results

Pfizer

Terminated

Long Term Safety Study of Tanezumab in Chronic Low Back Pain

Low Back Pain

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time

Chronic Pain

United States
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

An Open-label Extension Study With Flexible Dosing of Extended-release (ER) Tapentadol (CG5503) to Treat Patients With Moderate to Severe Chronic Pain

Pain | Osteoarthritis | Low Back Pain

United States, Australia, Canada, New Zealand
Pfizer

Completed

RN624 In Adult Patients With Chronic Low Back Pain

Low Back Pain

United States
Ortho-McNeil Janssen Scientific Affairs, LLC
Grünenthal GmbH

Completed

NUCYNTA (Tapentadol Immediate Release) Versus Oxycodone Immediate Release in the Treatment of Acute Low Back Pain

Pain | Back Pain | Low Back Pain | Back Pain With Radiation

United States
Pfizer

Completed

Randomized, Double Blind, Multicenter Study of the Safety and Efficacy of Valdecoxib 40 mg Once Daily Compared With Diclofenac 75 mg Twice Daily in Acute Low Back Pain

Low Back Pain

Chile, Venezuela, Ecuador, Colombia, Brazil, Mexico, Argentina, Peru, Costa Rica
Meda Pharmaceuticals

Completed

A Study to Evaluate Two Formulations of Carisoprodol in Subjects With Musculoskeletal Spasm of the Lower Back

Lower Back Pain

United States
Meda Pharmaceuticals

Completed

Study to Evaluate Two Formulations of Carisoprodol in Subjects With Musculoskeletal Spasm of the Lower Back

Lower Back Pain

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Six Week Study Of The Pain Relieving Effects Of Celecoxib 200 Mg Twice Daily Compared To Tramadol 50 Mg Four Times Daily In Patients With Chronic Low Back Pain

Low Back Pain

United States
Purdue Pharma LP

Completed

Efficacy and Safety of Oxycodone/Naloxone Controlled-release Tablets (OXN) Compared to Placebo in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
BioDelivery Sciences International

Completed

Efficacy Study to Evaluate Buprenorphine HCl Buccal Film in Opioid-Naive Subjects

Low Back Pain

United States
BioDelivery Sciences International

Completed

Efficacy Study to Evaluate Buprenorphine HCl Buccal Film in Opioid-Experienced Subjects

Low Back Pain

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets for Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Regeneron Pharmaceuticals

Completed

A Study to Determine the Efficacy and Safety of Fasinumab for the Treatment of Adults With Chronic Low Back Pain

Low Back Pain

United States, Poland, Canada, Hungary, Denmark, Estonia, Czechia
Purdue Pharma LP

Completed

Buprenorphine Transdermal System (BTDS) in Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Pfizer
Eli Lilly and Company

Completed

A Phase 3 Study of Tanezumab for Chronic Low Back Pain (TANGO)

Low Back Pain

United States, Spain, Korea, Republic of, Japan, Canada, Hungary, France, Sweden, Denmark
Neurana Pharmaceuticals, Inc.

Completed

Tolperisone in Acute Muscle Spasm of the Back (STAR)

Back Pain | Low Back Pain | Acute Pain | Muscle Cramp | Back Strain | Muscle Spasm | Back Spasm Upper Back

United States
Boston Scientific Corporation

Terminated

Effectiveness of Precision Spinal Cord Stimulation With Artisan Paddle Electrode

Back Pain | Chronic Pain | Pain in Leg, Unspecified

United States
Mesoblast, Ltd.
Quintiles, Inc.

Completed

Placebo-controlled Study to Evaluate Rexlemestrocel-L Alone or Combined With Hyaluronic Acid in Participants With Chronic Low Back Pain (MSB-DR003)

Degenerative Disc Disease

United States, Australia
BioDelivery Sciences International

Completed

Long-term Open-Label Safety Study to Evaluate EN3409

Osteoarthritis | Low Back Pain | Neuropathic Pain

United States
University of Johannesburg

Completed

The Efficacy of Lacticum Acidum Homaccord in the Treatment of Chronic Tension-type Headaches

Chronic Tension-type Headaches

South Africa
Purdue Pharma LP

Completed

A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Purdue Pharma LP

Completed

Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain

Low Back Pain

United States, Poland, Czech Republic, Italy
University of Cape Town
University of Michigan; Brigham and Women's Hospital; Fogarty International Center... and other collaborators

Completed

An Observational Study of Distress, Immune Function, and Pain in HIV.

Chronic Pain | HIV | Distress, Emotional | Central Sensitisation | Immune System and Related Disorders

South Africa
Jennifer Breel
Noordwest Ziekenhuisgroep; Rijnstate Hospital; Diakonessenhuis, Utrecht; Alrijne...

Completed

The Pain Suppressive Effect of Alternative Spinal Cord Stimulation Frequencies (HALO)

Neuropathic Pain | Failed Back Surgery Syndrome

Netherlands
Leiden University Medical Center
KU Leuven; Maastricht University; Universiteit Leiden

Completed

Pain-related Fear as a Facilitator of Nocebo Hyperalgesia (LFS)

Hyperalgesia | Chronic Pain Syndrome | Fear of Pain | Chronic Pain, Psychogenic

Netherlands
Leiden University Medical Center
VU University of Amsterdam; Universiteit Leiden

Completed

Electrophysiological Correlates of Nocebo Effects on Pain

Chronic Pain | Hyperalgesia | Chronic Pain Syndrome | Chronic Pain, Psychogenic

Netherlands
Cephalon

Completed

Evaluating the Safety and Tolerability of OraVescent Fentanyl for Opioid Tolerant Patients With Noncancer Related Breakthrough Pain

Diabetic Neuropathies | Osteoarthritis | Low Back Pain | Migraine

United States
Proove Bioscience, Inc.

Unknown

Observational Study of the Impact of Genetic Testing on Healthcare Decisions and Care in Interventional Pain Management (MOSAIC)

Pain | Back Pain | Musculoskeletal Pain | Chronic Pain | Neck Pain | Neuropathic Pain | Pain, Intractable | Nociceptive Pain

United States
Medical University of South Carolina

Completed

rTMS for Treatment of Pain and Craving

Pain, Chronic | Pain Acute

United States
Mylan Inc.
Theravance Biopharma

Completed

Revefenacin Peak Inspiratory Flow Rate (PIFR) Study in COPD

Chronic Obstructive Pulmonary Disease, COPD | Low Peak Inspiratory Flow Rate (PIFR)

United States
Boston Scientific Corporation

Terminated

Spinal Cord Stimulation With Precision® System Versus Reoperation for Failed Back Surgery Syndrome (Evidence)

Pain | Back Pain | Failed Back Surgery Syndrome

United States, United Kingdom, Canada, France
Neurana Pharmaceuticals, Inc.

Completed

Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm (RESUME-1)

Back Pain | Acute Pain | Back Muscle Spasm | Back Strain | Back Spasm Upper | Muscle Spasm

United States
Medical University of South Carolina
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

Safety and Efficacy of Mesenchymal Stem Cells Associated With Chronic Pancreatitis Pain (STEMCAP-1)

Chronic Pain | Chronic Pancreatitis

United States
VA Office of Research and Development

Recruiting

Novel Cellular Therapy for the Treatment of Pain Associated With Chronic Pancreatitis (MSCPainRelief)

Chronic Pain | Chronic Pancreatitis

United States
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Not yet recruiting

ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain (ACTION)

Chronic Pain | Opioid Withdrawal

United States
Leiden University Medical Center
Leiden University

Completed

Pain, Learning, and Nocebo (PIPLE)

Chronic Pain | Pain Syndrome

Netherlands
Medical University of South Carolina
National Institute of Nursing Research (NINR); National Institutes of Health...

Completed

Activate For Life: mHealth Intervention To Address Pain And Fatigue In Low-income Older Adults Aging In Place (Activate)

Aging | Fatigue Syndrome, Chronic | Pain, Chronic

United States
MedtronicNeuro

Terminated

Subcutaneous Nerve Stimulation for Failed Back Surgery Syndrome (FBSS) Patients (SubQStim)

Failed Back Surgery Syndrome | Post-laminectomy Syndrome

United States
Medical University of South Carolina

Completed

Discontinuation From Chronic Opioid Therapy For Pain Using a Buprenorphine Taper

Chronic Pain | Opioid Pain Medication

United States
University of South Australia

Completed

Hypnotic Intervention for Women With Chronic Pelvic Pain

Chronic Pain | Pelvic Pain | Psychological | Hypnosis, Animal

Australia
Carolinas Center for Advanced Management of Pain
Abbott Medical Devices

Completed

Optimal Stimulation Programming for Spinal Peripheral Neuromodulation

Chronic Pain

United States
Medical University of South Carolina

Terminated

Ketamine in Chronic Kid's (KiCK) Pain (KiCK Pain)

Chronic Pain

United States
Clemson University

Recruiting

Mindful Walking for Adults With Chronic Pain

Chronic Pain

United States
Medical University of South Carolina

Completed

Effect of Epidural Stimulation on Muscle Activation and Sensory Perception

Chronic Pain

United States
InHealth Group

Unknown

Staff Experiences of Using Virtual Reality in a Pain Management Group

Chronic Pain

United Kingdom
Medical University of South Carolina

Completed

Effects of Transcranial Magnetic Stimulation (TMS) and Stimulus Controllability on Pain Perception

Chronic Pain

United States
University of Adelaide

Unknown

The Progression From Dysmenorrhoea to Chronic Pelvic Pain

Chronic Pain | Pelvic Pain | Dysmenorrhoea

Australia
Leiden University Medical Center
Universiteit Leiden

Completed

The Role of Learning in Nocebo Hyperalgesia

Chronic Pain | Hyperalgesia | Pain Syndrome | Nocebo Effects

Netherlands
Yale University
National Center for Complementary and Integrative Health (NCCIH)

Active, not recruiting

Cooperative Pain Education and Self-management: Expanding Treatment for Real-world Access (COPES ExTRA) (COPES ExTRA)

Pain, Chronic

United States

Clinical Trials on Chronic Nonspecific Low Back Pain in South Africa

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