Clinical Trials on Chronic Obstructive Pulmonary Disease, COPD in United Kingdom

Total 18927 results

Xiromed LLC
Laboratorios Liconsa; Exeltis

Completed

Bioequivalence Study of Tiotropium 18 μg Inhalation Powder, Hard Capsule With Spiriva®Handihaler® 18 μg Inhalation Powder, Hard Capsule in Patients With Chronic Obstructive Pulmonary Disease (COPD) (ARBORUS)

COPD

United States, India
Novartis Pharmaceuticals

Completed

A Multi-centre Randomized Double Blind 52-week Study to Assess the Safety of QVA149 Compared to QAB149 in Patients With COPD Who Have Moderate to Severe Airflow Limitation

Chronic Obstructive Pulmonary Disease (COPD)

United States, Romania, Hungary, Bulgaria, Spain, Finland, Puerto Rico
Novartis

Completed

Safety, Tolerability and Efficacy of Indacaterol in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)

COPD

United States, Argentina, Germany, Spain, Canada, India, Turkey, Sweden, Italy
Imperial College London

Completed

Macrophage Phagocytosis in COPD

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United Kingdom
AstraZeneca

Recruiting

Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations (OBERON)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Canada, Czechia, Denmark, Hungary, Netherlands, Spain, Korea, Republic of, Argentina, Belgium, Bulgaria, Finland, India, Japan, Mexico, Norway, Sweden, Turkey, Vietnam, Portugal, Puerto Rico
AstraZeneca

Completed

Evaluation of Onset of Effect in Patients With Severe Chronic Obstructive Pulmonary Disease (COPD) Treated With Symbicort® Compared to Seretide® (SPEED)

Chronic Obstructive Pulmonary Disease (COPD)

Brazil, United Kingdom, Germany, Philippines, Denmark, Australia, Argentina, India, Belgium
Pearl Therapeutics, Inc.

Completed

Multi-Center Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD (PINNACLE 2)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Queen's University, Belfast

Completed

Effect of Increased Fruit and Vegetable Intake on Chronic Obstructive Pulmonary Disease (COPD) (DISCO)

Chronic Obstructive Pulmonary Disease

United Kingdom
Respivert Ltd

Completed

A Study to Investigate How Safe and Well Tolerated RV568 is in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Chiesi Farmaceutici S.p.A.

Terminated

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of CHF6297 in Healthy Subjects and Patients With COPD (CHF6297 FIH)

Chronic Obstructive Pulmonary Disease

United Kingdom
Imperial College London

Completed

Leukocyte Function in Chronic Obstructive Pulmonary Disease (COPD)

Emphysema | COPD | Chronic Bronchitis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Fibre Specific Signalling in the Locomotor Myopathy of Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United Kingdom
Novartis Pharmaceuticals

Completed

A 12 Week Treatment, Multi-center, Randomized, Double-blind, Parallel-group, Placebo and Active Controlled Study to Assess the Efficacy, Safety, and Tolerability of Indacaterol Maleate / Glycopyrronium Bromide in COPD Patients With Moderate to Severe Airflow Limitation.

Chronic Obstructive Pulmonary Disease (COPD)

United States, Poland, Romania, Canada, Philippines, Spain, Ukraine, Vietnam
AstraZeneca
Parexel

Completed

Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of AZD8871 in Healthy Subjects

Chronic Obstructive Pulmonary Disease

United Kingdom
University of Leicester
Aparito Ltd.

Not yet recruiting

Role of Inhaler Adherence and Blood Eosinophil Count in Exacerbations of COPD (INCLINE)

Chronic Obstructive Pulmonary Disease | Adherence, Treatment

United Kingdom
University of Southampton
GlaxoSmithKline

Completed

An Investigation of the Mechanism of Action of Seretide in Chronic Obstructive Pulmonary Disease (IMAS)

Chronic Obstructive Pulmonary Disease

United Kingdom
University of Vermont
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study of the Effects of Education on Patients With Chronic Obstructive Pulmonary Disease

COPD

United States
Dr Ian B Wilkinson
University College London Hospitals; Imperial College London; Newcastle University and other collaborators

Recruiting

Optimising Azithromycin Prevention Treatment in COPD to Reduce Exacerbations (OPACE)

Chronic Obstructive Pulmonary Disease

United Kingdom
Novartis Pharmaceuticals

Completed

A 12-week Treatment, Multi-center, Randomized, Double-blind, Parallel-group, Placebo and Active Controlled Study to Assess the Efficacy, Safety, and Tolerability of Indacaterol Maleate / Glycopyrronium Bromide in COPD Patients With Moderate to Severe Airflow Limitation

Chronic Obstructive Pulmonary Disease (COPD)

United States, Colombia, Egypt, Hungary, France, Guatemala, Panama, Slovakia, Slovenia
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Dose in Healthy Volunteers, Repeat Doses in Asthmatic Patients and of Single Dose in COPD Patients of CHF6366

Chronic Obstructive Pulmonary Disease | Asthma

United Kingdom
Mrs Hanoof Aljohani
University Hospitals, Leicester

Recruiting

Home-based Body Weight Exercise With Blood Flow Restriction (BFR): Feasibility of a Novel Rehabilitation Intervention in COPD Patients (HomeBFR-COPD) (HomeBFR-COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
AstraZeneca

Recruiting

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease (THARROS)

COPD (Chronic Obstructive Pulmonary Disease)

France, Denmark, Italy, Spain, United States, Canada, Argentina, Japan, Colombia, Germany, Peru, Brazil, China, India, Thailand, Austria, Serbia, Malaysia, Philippines, Poland, Taiwan, Greece, Norway, Sweden, Mexico, Romania, Korea, Republic... and more
Hoffmann-La Roche

Recruiting

A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (ARNASA)

Chronic Obstructive Pulmonary Disease (COPD)

United States, China, Spain, Italy, Germany, Belgium, Korea, Republic of, Poland, Taiwan, Israel, New Zealand, Sweden, United Kingdom, Japan, Czechia, Philippines, Hong Kong, Greece, Australia, Thailand, Netherlands, Argentina, Brazil, Fran... and more
Chiesi Farmaceutici S.p.A.

Recruiting

PASS to Assess Cardiovascular and Cerebrovascular Events in COPD Patients Initiating Fixed Triple Therapy (DPI or pMDI) (TRIBE)

Chronic Obstructive Pulmonary Disease

United Kingdom
Imperial College London

Withdrawn

Inhaled Mannitol and Ciliary Beat Frequency in COPD Patients

Chronic Obstructive Pulmonary Disease

United Kingdom
South Eastern Health and Social Care Trust

Completed

Telehealth Monitoring in Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United Kingdom
Novartis

Completed

Efficacy of DNK333 in Patients With COPD and Cough

Chronic Obstructive Pulmonary Disease

United Kingdom, Netherlands
Hull University Teaching Hospitals NHS Trust

Completed

Effect on Adrenal Function of Budesonide Versus Fluticasone in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Iron and Chronic Obstructive Pulmonary Disease (COPD) Exercise Trial (ICE-T)

Chronic Obstructive Pulmonary Disease

United Kingdom
Pearl Therapeutics, Inc.

Completed

Extension Study to Evaluate the Safety and Efficacy of PT003, PT001, and PT005 in Subjects With Moderate to Very Severe COPD, With Spiriva® Handihaler® (PINNACLE 3)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Australia, New Zealand
Imperial College London

Completed

Characteristics That Identify Exacerbation Risk Following Colds in COPD Patients

Chronic Obstructive Pulmonary Disease

United Kingdom
VA Office of Research and Development

Completed

An Intervention to Improve Function in Severe Cardiopulmonary Illness

Heart Failure | Chronic Obstructive Pulmonary Disease (COPD)

United States
Royal Brompton & Harefield NHS Foundation Trust

Unknown

LVR in Severe Emphysema Using Bronchoscopic Autologous Blood Instillation in Combination With Intra-bronchial Valves (BLOOD-VALVES)

Chronic Obstructive Pulmonary Disease | Emphysema

United Kingdom
AstraZeneca

Recruiting

A Study to Investigate the Effect on Lung Function of an Approved COPD Treatment (BGF, With HFA Propellant) Compared to BGF Formulated With a New Propellant (HFO) in Participants 40 to 80 Years of Age With COPD

COPD (Chronic Obstructive Pulmonary Disease)

United States, Korea, Republic of, Argentina, Turkey, Vietnam, Malaysia, Philippines, Thailand, Hungary, Mexico, Canada, India, Bulgaria, Poland
NHS Tayside
NHS Fife

Withdrawn

Steroid Withdrawal Intervention in Fife and Tayside (SWIFT)

Chronic Obstructive Pulmonary Disease

United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

PK of BDP/FF/GB Single-inhaler Triple Therapy in Japanese vs. Caucasians

Chronic Obstructive Pulmonary Disease | Asthma

United Kingdom
University of Lincoln
National Health Service, United Kingdom

Completed

Changes in Inflammatory Markers During Pulmonary Rehabilitation Based on Exacerbation States in COPD (CIMPRES-COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

Myotrace: An Evaluation of a Novel Critical Illness Monitoring System

Chronic Obstructive Pulmonary Disease

United Kingdom
Respivert Ltd

Completed

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Repeat Doses of RV1729 for 28 Days in Patients With COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); University of Michigan; Duke... and other collaborators

Completed

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 1) (CAPTURE)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); University of Michigan; Duke... and other collaborators

Completed

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3) (CAPTURE)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Northumbria Healthcare NHS Foundation Trust
GlaxoSmithKline; Newcastle University; Chiesi UK

Recruiting

Eosinopenia in Severe COPD Exacerbation (A-TREC)

Chronic Obstructive Pulmonary Disease

United Kingdom
Hywel Dda Health Board
Swansea University

Completed

sTep dOWn Inhalers in the reAl woRlD (TOWARD)

Chronic Obstructive Pulmonary Disease

United Kingdom
MedImmune LLC

Completed

Safety and Tolerability of MEDI3506 in Healthy Participants, in Participants With COPD and Healthy Japanese Participants

Part I (SAD) - Healthy Participants | Part II (MAD) - Chronic Obstructive Pulmonary Disease | Part III (J-SD) - Healthy Japanese Participants

United Kingdom
BioMarck Pharmaceuticals, Ltd.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effectiveness and Safety of BIO-11006 Inhalation Solution to Treat the Overproduction of Mucus and Inflammation in COPD (BREATH-1)

Chronic Obstructive Pulmonary Disease | COPD

United States
StratiHealth

Completed

Use of Respiratory Therapists (RTs) to Improve Outcomes and Quality of Life in Patients With COPD (RTQOL)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Sheffield Teaching Hospitals NHS Foundation Trust
Novartis

Completed

SILO2 (Signal Intensity Lung washOut) (SILO2)

Chronic Obstructive Pulmonary Disease

United Kingdom
Medtronic Cardiac Rhythm and Heart Failure

Completed

Reveal LINQ for Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Queen Mary University of London
GlaxoSmithKline; British Lung Foundation

Completed

Withdrawal of Inhaled Corticosteroids in Patients With COPD in Primary Care

Chronic Obstructive Pulmonary Disease

United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Inhaled CHF6001 (CHF6001Ext)

Chronic Obstructive Pulmonary Disease

United Kingdom

Clinical Trials on Chronic Obstructive Pulmonary Disease, COPD in United Kingdom

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