Clinical Trials on Clinically Significant Portal Hypertension

Total 503 results

Sensimed AG

Completed

Relationship Between 24-hour IOP Pattern and the 24-hour Blood Pressure Pattern in Patients With POAG

Primary Open Angle Glaucoma | Normal Tension Glaucoma

Poland
University Hospital, Basel, Switzerland

Withdrawn

The Antioxidant Effect of Routine Vascular Therapy for Normal Tension Glaucoma Patients

Primary Open Angle Glaucoma
Nanfang Hospital of Southern Medical University
LanZhou University; Chulalongkorn University; Beijing 302 Hospital; Xijing Hospital... and other collaborators

Recruiting

Transient Elastography (FibroTouch) for Assessing Risk of Gastroesophageal Varices Bleeding in Compensated Cirrhosis (Pan-CHESS1801)

Compensated Liver Cirrhosis | Gastroesophageal Varices Bleeding

China, Japan, Indonesia, Thailand, Turkey
Shanghai Zhongshan Hospital

Unknown

Anticoagulation in Gastroesophageal Varices and JAK2 Mutation

Myeloproliferative Neoplasm | Gastroesophageal Varices | JAK2 Mutation
University of Zurich
Cantonal Hosptial Aarau, Department of Ophthalmology, Aarau, Switzerland

Completed

Reproducibility of Blood Flowmetry in Human Retina Using the Nidek Laser Speckle Flowgraphy LSFG-NAVI System (LSFG Repro)

Healthy | Open Angle Glaucoma | Normal Tension Glaucoma

Switzerland
Centre Hospitalier Universitaire Dijon

Completed

Circulating Oxidative Stress and Gestational Hypertension. Study of the Evolution of Free-radical Markers of Oxidative Stress From Before to After Childbirth in Two Groups of Women: Normal Pregnancy and Pre-eclampsia.

Normal Pregnancy | Pregnancy Complicated by Pre-eclampsia.

France
Universitaire Ziekenhuizen KU Leuven

Unknown

Correlation of Orbital Cerebrospinal Fluid Pressure and Retinal Venous Outflow in Primary Open-angle Glaucoma

Primary Open Angle Glaucoma | Normal Tension Glaucoma

Belgium
Institute of Liver and Biliary Sciences, India

Completed

Utility of Liver and Splenic Stiffness in Predicting Esophageal Varices in Patients With Acute on Chronic Liver Failure

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Efficacy of Nonselective Beta Blocker vs Placebo in Patients With Acute-on-chronic Liver Failure With Small/ no Esophageal Varices

Acute on Chronic Liver Failure

India
United Arab Emirates University
Tawam Hospital

Completed

Non-invasive Prediction of Esophageal Varices in Patients With Non-Alcoholic Fatty Liver Disease With Advanced Fibrosis

Compensated Cirrhosis | Non-alcoholic Fatty Liver | Esophageal Varices

United Arab Emirates
Rigshospitalet, Denmark
Lundbeck Foundation

Unknown

Study on Baroreceptor Function in Relation to Orthostatic Blood Pressure Regulation After Hip Surgery

Hypotension, Orthostatic | Total Hip Replacement

Denmark
Edward Via Virginia College of Osteopathic Medicine
Virginia Polytechnic Institute and State University

Completed

Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community

Hepatitis | Cholecystitis | Ascites | Pancreatitis | Urolithiasis | Cholangitis | Portal Hypertension | Cholelithiasis | Hydronephrosis | Abdominal Aortic Aneurysm | Abnormal Uterine Bleeding | Ovarian Torsion | Blunt Abdominal Trauma | Ovarian Mass

Dominican Republic
Qlaris Bio, Inc.

Not yet recruiting

Qlaris Phase 2 Study in NTG Patients

Glaucoma | Normal Tension Glaucoma (NTG) | Low-Tension Glaucoma, Bilateral | Low-Tension Glaucoma, Unspecified Eye

Korea, Republic of, Philippines
National Taiwan University Hospital
Insight Medical Solutions

Recruiting

Wired Magnetically Assisted Capsule Endoscopy and Esophageal Varices

Esophageal Varices

Taiwan
The First Affiliated Hospital of Nanchang University

Unknown

Follow-up Study of Complications of Acute Pancreatitis (FSCAP)

Metabolic Diseases | Quality of Life | Respiratory Failure | Pancreatic Neoplasms | Hypertension, Portal | Pancreatitis

China
Yunsheng Yang

Unknown

Effects of Somatostatin on Post-endoscopic Portal Hemodynamic in Cirrhotic Patients With Esophageal Gastric Varices

Esophageal Varices Secondary to Cirrhosis of Liver

China
Hospital of Stomatology, Wuhan University

Recruiting

The Combination of Adebrelimab and TP Regimen for Neoadjuvant Therapy in Patients With Stage IVB Oral Squamous Cell Carcinoma

Clinical IVb Stage Oral Squamous Cell Carcinomas Patients

China
Wills Eye
Optovue

Completed

Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study

Primary Open-angle Glaucoma | Normal Tension Glaucoma | Glaucoma; Drugs

United States
Medical University of South Carolina
Ohio State University; University of Texas Southwestern Medical Center; University...

Recruiting

Comparison of 24-hours Versus 72-hours of Octreotide Infusion in Preventing Early Rebleed From Esophageal Varices (LOVARB)

Upper Gastrointestinal Bleeding | Liver Cirrhoses | Esophageal Varices | Bleeding Esophageal Varices

United States
Galectin Therapeutics Inc.

Active, not recruiting

Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis (NAVIGATE)

Cirrhosis | NASH - Nonalcoholic Steatohepatitis | Prevention of Esophageal Varices

United States, France, Spain, Australia, Canada, Israel, Puerto Rico, Belgium, Argentina, Chile, Germany, Korea, Republic of, Mexico, Poland, United Kingdom
Hospital Vall d'Hebron

Completed

Endoscopic Variceal Ligation in Children

Child | Endoscopy | Upper Gastrointestinal Bleeding | Esophageal Varices in Cirrhosis of the Liver
Austin Health

Completed

Endoscopy-related Phone Consultation During the COVID-19 Outbreak

Reflux, Gastroesophageal | Colon Disease | Colon Polyp | Varices, Esophageal

Australia
Taipei Veterans General Hospital, Taiwan

Unknown

Impact of Nonselective Beta-blocker on Acute Kidney Injury in Cirrhotic Patients With Esophageal Varices (AKI)

Cirrhosis | Acute Kidney Injury | Esophageal Varices

Taiwan
Centre Hospitalier Universitaire Dijon

Completed

Contribution of High Throughput RNA Sequencing Combined With Sequencing of Whole Genomes in the Diagnosis of Intellectual Disability (DI-WA)

Patients With Intellectual Disabilities Without an Obvious Clinical Diagnosis | Patients With Normal Array CGH and Previous Negative Genetic Investigations (WES-solo or WES-trio)

France
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial) (VALUE)

High Blood Pressure | Coarctation of Aorta

United States
Qilu Hospital of Shandong University
Shandong Provincial Hospital; Taian City Central Hospital

Recruiting

Safety of Anticoagulant Therapy After Tissue Glue for Gastric Varices

Anticoagulants and Bleeding Disorders | Tissue Adhesion | Gastric Varices Bleeding

China
Taipei Veterans General Hospital, Taiwan

Recruiting

Primary Prevention of Patients With Hepatocellular Carcinoma and Concomitant Esophageal Varices (P-HCC)

Hepatocellular Carcinoma | Bleeding Esophageal Varices

Taiwan
National Cancer Institute (NCI)

Recruiting

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Melanoma | Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage IV HPV-Mediated... and other conditions

United States
Kyorin University

Completed

Macular Retinoschisis and Detachment Associated With Glaucomatous Optic Neuropathy

Normal Tension Glaucoma | Macular Retinoschisis | Macular Detachment

Japan
Mayo Clinic

Withdrawn

A Pneumatic Compression Device for the Treatment of Lymphedema in Patients With Stage II-IV Head and Neck Cancer After Chemoradiation

Head and Neck Carcinoma | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IV Hypopharyngeal Carcinoma AJCC v8 | Stage IV Laryngeal Cancer AJCC v8 | Stage... and other conditions
Rabin Medical Center

Unknown

Protective Effect of Phenytoin on Glaucoma

Primary Open Angle Glaucoma | Normal Tension Glaucoma | Secondary Open Angle Glaucoma | Narrow-Angle Glaucomas

Israel
University College Dublin
Royal College of Surgeons, Ireland; National Maternity Hospital, Ireland; Perinatal...

Completed

Trial of Early Screening Test for Pre-eclampsia and Growth Restriction (TEST)

Placenta Diseases | Pre-Eclampsia | Fetal Growth Retardation | Eclampsia Preeclampsia | Foetal Growth Restriction

Ireland
University Hospital, Clermont-Ferrand
UMR 1019, Unité de Nutrition Humaine, INRA, Centre Auvergne-Rhône Alpes; UMR...

Completed

Nutritional Transitions to More Plant Proteins and Less Animal Proteins: Understanding the Induced Metabolic Reorientations and Searching for Their Biomarkers (ProVegOmics) (ProVegOmics)

Metabolic Syndrome | Hypertriglyceridemia | Fasting Blood Sugar Above Normal | Lower Than Standard HDL-cholesterol Level | Slightly Elevated Blood Pressure

France
Rong Zhang
National Institute on Aging (NIA); Michigan State University; Texas Health Resources

Recruiting

Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study) (IPAT)

Hypertension | Subjective Cognitive Decline | Cognitively Normal Older Adults | Family History of Dementia

United States
Technische Universität Dresden
Fraunhofer Institute for Ceramic Technologies and Systems IKTS

Completed

Computer-aided Diagnosis of Ocular Diseases Based on Corneal Biomechanics (EyeTwin)

Glaucoma | Corneal Astigmatism | Keratoconus | Open Angle Glaucoma | Corneal Ectasia | Corneal Disease | Normal Tension Glaucoma

Germany
University of Texas Southwestern Medical Center
Washington University School of Medicine; University of Kansas Medical Center; Pennington Biomedical Research Center and other collaborators

Completed

Risk Reduction for Alzheimer's Disease (rrAD)

Hypertension | Subjective Cognitive Decline | Cognitively Normal Older Adults | Family History of Alzheimer's Disease

United States
China Medical University Hospital

Completed

Acupuncture Effect on Digestion in Critically Ill Post-Operative Oral and Hypo-pharyngeal Cancer Patients

Hypopharyngeal Cancer | Oral Cancer

Taiwan
Replicor Inc.

Available

Replicor Compassionate Access Program (RCAP)

Decompensated Cirrhosis | Hepatocellular Carcinoma | Cirrhosis, Liver | Ascites Hepatic | Viral Hepatitis B | Viral Hepatitis D | Varices, Esophageal

Austria, France, Israel
Integrative Phenomics
Assistance Publique - Hôpitaux de Paris; Assistance Publique Hopitaux De Marseille and other collaborators

Not yet recruiting

Individual Factors Related to Chronic Low-grade Inflammation and Cardiometabolic Disease Risk (PINEAPPL)

Hypertension | Healthy | Obesity | Overweight | Metabolic Syndrome | Hypercholesterolemia | Risk Factor, Cardiovascular | Abdominal Obesity | Normal Weight Adults | Low-grade Inflammation | Metabolically Healthy Controls
Oxford University Hospitals NHS Trust

Completed

Assessment of the Effects of Pressors on Graft Blood Flow After Free Tissue Transfer Surgery (Free4Flow)

Head and Neck Cancer | Hypotension | Oral Cancer | Free Flap

United Kingdom
Stony Brook University

Active, not recruiting

A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies

Parkinson Disease | Multiple System Atrophy | Normal Pressure Hydrocephalus | Rapid Eye Movement Sleep Behavior Disorder

United States
Northwell Health

Not yet recruiting

Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing Blindness

Obstructive Sleep Apnea | Normal Tension Glaucoma

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck

Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage IV Hypopharyngeal Carcinoma AJCC v8 | Stage IV Laryngeal Cancer AJCC v8 | Stage... and other conditions

United States
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVA Lip and Oral... and other conditions

United States
Hyunseok Kang, MD
NRG Oncology

Completed

Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin

Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IV Hypopharyngeal... and other conditions

United States
Sheba Medical Center

Enrolling by invitation

Brain Network Activation in Patients With Movement Disorders (BNA-MDi)

Parkinson Disease | Cerebellar Ataxia | Dystonia | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Essential Tremor | Dementia With Lewy Bodies | Normal Pressure Hydrocephalus

Israel
Marcelo Bonomi

Recruiting

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck Cancer

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive)... and other conditions

United States
National Cancer Institute (NCI)
NRG Oncology; Canadian Cancer Trials Group

Active, not recruiting

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage... and other conditions

United States, Canada
National Cancer Institute (NCI)

Recruiting

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage IV Hypopharyngeal... and other conditions

United States

Clinical Trials on Clinically Significant Portal Hypertension

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