Clinical Trials on Clostridium; Sepsis

Total 3664 results

Michael E Villarreal, MD
Merck Sharp & Dohme LLC

Terminated

Comparing the Effectiveness of IV Bezlotoxumab Versus Placebo in Decreasing Morbidity and Mortality in Patients With Fulminant C. Diff Requiring Surgery.

Clostridia Difficile Colitis | Clostridium; Sepsis

United States
Indonesia University

Completed

Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in Sepsis

Severe Sepsis With Septic Shock | Severe Sepsis Without Septic Shock

Indonesia
Ascension Genesys Hospital

Unknown

Clostridial Infection and Oral Lavage -Improving Treatment Before Illness Becomes Severe (COLITIS)

Clostridium Difficile Colitis

United States
University of Virginia
Imperial College London

Recruiting

Alanyl-glutamine Supplementation for C. Difficile Treatment (ACT) (ACT)

Clostridium Difficile Infection | Clostridium Difficile Diarrhea | Clostridioides Difficile Infection | Clostridia Difficile Colitis

United States
German Center for Neurodegenerative Diseases (DZNE)
University Hospital, Bonn

Unknown

Long-term Cognitive and Cerebral Changes in Sepsis Survivors and Their Predictors (BonSEP)

Severe Sepsis With Septic Shock | Severe Sepsis Without Septic Shock

Germany
Yonsei University

Completed

Effects of Early Exercise Rehabilitation on Long-term Functional Recovery in Patients With Severe Sepsis

Severe Sepsis or Septic Shock

Korea, Republic of
University of Rostock

Completed

Extracorporeal Immune Support System (EISS) for the Treatment of Septic Patients (EISS-1)

Severe Sepsis and Septic Shock

Germany
University Hospital, Strasbourg, France

Unknown

Membrane Shedding During Severe Sepsis and Septic Shock: Pathophysiological and Clinical Relevance

Severe Sepsis and Septic Shock

France
Peking Union Medical College Hospital

Unknown

Using Sodium Lactate Ringer's Injection Resuscitate Septic Shock Patients

Lactate | Severe Sepsis With Septic Shock
University of Utah
National Institutes of Health (NIH)

Completed

VTE Incidence in Severe Sepsis and Septic Shock

Severe Sepsis With Septic Shock
Klinikum Emden
Universitätsklinikum Hamburg-Eppendorf; Kantonsspital Baden; Kantonsspital Münsterlingen

Completed

Evaluating a CytoSorb Score in Septic Shock (ECSISS)

Severe Sepsis With Septic Shock

Germany
Centre Hospitalier Universitaire Dijon

Completed

COrporeal Compression at the ONset of Severe Sepsis and Septic Shock (COCOON)

Fluid Resuscitation | Severe Sepsis or Septic Shock

France
Assistance Publique - Hôpitaux de Paris

Completed

Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock (SSS)

Severe Septic Syndrome (Severe Sepsis and Septic Shock) Diagnosed and Treated by Mobile Intensive Care Unit

France
Assistance Publique - Hôpitaux de Paris

Completed

Predictive Mini-bolus Fluid Responsiveness in Pediatric Septic Shock (PRECISE)

Severe Sepsis or Septic Shock in Pediatric Intensive Care Unit

France
University Medicine Greifswald

Unknown

Bedside vs. Standard Microbiological Blood Culture Diagnostics - BEMIDIA Study (BEMIDIA)

Sepsis Septic Shock

Germany
McMaster University
Canadian Institutes of Health Research (CIHR); The Physicians' Services Incorporated...

Recruiting

Fluids in Septic Shock (FISSH) (FISSH)

Sepsis, Septic Shock

Canada, Saudi Arabia
Australian and New Zealand Intensive Care Research...
University of Pittsburgh; Intensive Care National Audit & Research Centre

Completed

Statistical Analysis Plan for an Individual Patient Data Meta-analysis of Three, International Trials Comparing Protocolised With Usual Resuscitation in Patients Presenting to the Emergency Department With Severe Sepsis and Septic Shock

Severe Sepsis and Septic Shock
Mansoura University

Unknown

Adjuvant Use of Neostigmine in Sepsis and Septic Shock.

Sepsis, Septic Shock

Egypt
Charite University, Berlin, Germany

Completed

IL 6 Measurement Using a New Densitometric Bedside (POC) Test

Sepsis, Septic Shock

Germany
University of Alberta
University of British Columbia; McGill University; University of Calgary

Active, not recruiting

Multicentre Blinded Comparison of Lyophilized Sterile Fecal Filtrate to Lyophilized Fecal Microbiota Transplant in Recurrent Clostridioides Difficile Infection

Clostridium Difficile Diarrhea | Clostridia Difficile Colitis

Canada
Sutep Jaruratanasirikul
Prince of Songkla University

Completed

Piperacillin/Tazobactam in Critically Ill Patients With Severe Sepsis and Septic Shock

Early Phase of Severe Sepsis and Septic Shock

Thailand
Sutep Jaruratanasirikul
Prince of Songkla University

Completed

Population Pharmacokinetics and Monte Carlo Dosing Simulations of Meropenem During the Early Phase of Severe Sepsis and Septic Shock in Critically Ill Patients in Intensive Care Units

Initial Phase of Severe Sepsis and Septic Shock

Thailand
Yale University

Withdrawn

Study of Low Carbohydrate Enteral Nutrition in Patients With Bacterial Septic Shock

Bacterial Sepsis

United States
Università Politecnica delle Marche

Completed

Effects on Microcirculation of IgGAM in Severe Septic/Septic Shock Patients.

Septic Shock | Severe Sepsis

Italy
Mahidol University
Siriraj Hospital

Completed

Early Use of Norepinephrine in Septic Shock Resuscitation (CENSER)

Septic Shock | Severe Sepsis

Thailand
M.D. Anderson Cancer Center

Withdrawn

Early Metabolic Support as a Potential Solution to Multi-Organ Dysfunction Syndrome (MODS) During Severe Sepsis

Septic Shock
Federal University of Minas Gerais
Fundação de Amparo à Pesquisa do estado de Minas Gerais

Completed

Use of Inflammatory Biomarkers to Guide Antibiotic Therapy in Patients With Severe Infections

Septic Shock | Severe Sepsis

Brazil
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Comparison of Pediatric Septic Shock Treatment With and Without Central Venous Oxygen Saturation Monitoring

Septic Shock | Severe Sepsis

Brazil
Melbourne Health
University of Melbourne; Monash Medical Centre; The Florey Institute of Neuroscience...

Recruiting

High-dose Intravenous Vitamin C in Patients With Septic Shock (HIGH-VIS)

Septic Shock | Sepsis, Severe

Australia
Cairo University

Unknown

Effect of Dexmedetomidine on Perfusion Index and Microcirculation in Severe Sepsis and Septic Shock Patients

Septic Shock

Egypt
InflaRx GmbH

Completed

Studying Complement Inhibition in Early, Newly Developing Septic Organ Dysfunction (SCIENS)

Septic Shock | Severe Sepsis

Germany
Loma Linda University
Wayne State University; University of Massachusetts, Worcester; VA Loma Linda...

Terminated

Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock (MiCHO)

Septic Shock | Severe Sepsis

United States
Università Politecnica delle Marche
Azienda Ospedaliero, Universitaria Ospedali Riuniti

Completed

Activated Protein C and Microcirculation

Septic Shock | Severe Sepsis

Italy
Università Politecnica delle Marche

Completed

Circulating Free Hemoglobin and Microcirculation After Administration of Paracetamol in Febrile Septic Patient

Sepsis and Septic Shock

Italy
Intermountain Health Care, Inc.

Completed

Echo vs. EGDT in Severe Sepsis and Septic Shock (ECHO RCT)

Septic Shock | Severe Sepsis

United States
Universitätsmedizin Mannheim

Completed

Microcirculatory Oxygen Uptake in Sepsis

Sepsis | Septic Shock | Severe Sepsis

Germany
University of Pittsburgh
National Institute of General Medical Sciences (NIGMS)

Completed

Protocolized Care for Early Septic Shock (ProCESS)

Sepsis | Septic Shock | Severe Sepsis

United States
Seoul National University Hospital

Unknown

Methylene Blue in Severe Sepsis and Septic Shock

Septic Shock | Severe Sepsis

Korea, Republic of
Aragon Institute of Health Sciences
Ministerio de Sanidad, Servicios Sociales e Igualdad

Unknown

Efficacy of Melatonin in Patients With Severe Sepsis or Septic Shock

Septic Shock | Severe Sepsis

Spain
Medical Centre Leeuwarden
Lithuanian University of Health Sciences

Completed

Microcirculatory Changes During Magnesium Sulphate Infusion in Sepsis

Septic Shock | Severe Sepsis

Lithuania
Ottawa Hospital Research Institute
Baxter Healthcare Corporation; Canadian Blood Services

Completed

Fluid Resuscitation in Early Septic Shock (PRECISE)

Sepsis | Septic Shock | Severe Sepsis

Canada
Universitätsmedizin Mannheim

Recruiting

Mannheim Register of Sepsis and Septic Shock (MARSS)

Septic Shock | Severe Sepsis

Germany
HealthPartners Institute

Terminated

EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mortality in Patients With Severe Sepsis and Septic Shock

Sepsis | Septic Shock | Sepsis, Severe

United States
Children's Hospital Medical Center, Cincinnati

Completed

Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock

Septic Shock | Severe Sepsis

United States
Center for Sepsis Control and Care, Germany
Hannover Medical School; German Federal Ministry of Education and Research; University... and other collaborators

Completed

Quality Improvement in Infection COntrol and Sepsis Management in MOdel Regions (icosmos)

Sepsis | Septic Shock | Severe Sepsis

Germany
Hospices Civils de Lyon

Completed

GM-CSF to Decrease ICU Acquired Infections (GRID)

Septic Shock | Severe Sepsis

France
Amsterdam UMC, location VUmc
Stichting Nuts Ohra; Nederlandse Internisten Vereniging ( Dutch Association...

Completed

Prehospital Antibiotics Against Sepsis Trial (PHANTASi)

Sepsis | Septic Shock | Severe Sepsis

Netherlands
National Taiwan University Hospital

Terminated

Investigate the Activity of Endotoxin in Severe Sepsis

Septic Shock | Severe Sepsis

Taiwan
European Society of Intensive Care Medicine
Society of Critical Care Medicine (SCCM)

Completed

International Multicentre Prevalence Study on Sepsis (IMPRESS)

Septic Shock | Severe Sepsis

Belgium
Green Cross Corporation
Symyoo

Terminated

GCIV as an Adjuvant Therapy for Community-Acquired Severe Sepsis or Septic Shock

Septic Shock | Severe Sepsis

Korea, Republic of

Clinical Trials on Clostridium; Sepsis

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