International Multicentre Prevalence Study on Sepsis (IMPRESS)

Surviving Sepsis Campaign. International Multicentre Prevalence Study on Sepsis.

To mark 10 years of the Surviving Sepsis Campaign (SSC), and timed to coincide with World Sepsis Day, on September 13, 2013, the SSC, ESICM and SCCM will be conducting an international point prevalence study of severe sepsis and septic shock. The goal of this project is to determine the world wide burden of severe sepsis and define current practices of sepsis care internationally. The study is a simple data collection exercise for patients presenting with either severe sepsis or septic shock on World Sepsis Day.

Study Overview

• Status: Completed
• Conditions: Septic Shock; Severe Sepsis

Detailed Description

De---identified patient---level data will be collected on patients presenting to a participating intensive care unit or emergency department with severe sepsis or septic shock over a 24 hour period from 00:00 to 24:00 November 07, 2013. De---identified data that is already collected as part of routine clinical care will be collected for this study. Data to be collected includes hospital and ICU characteristics, patient characteristics, severity of illness, and adherence to SSC bundle elements and mortality. It will take between 30---60 minutes to collect and enter data for each patient admitted with severe sepsis or septic shock over the 24 hours study period.

• Study Type: Observational
• Enrollment (Anticipated): 1000

Contacts and Locations

Study Locations

• Belgium
  • Brussels, Belgium
    • All centres willing to contribute are welcome.

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

patients presenting with either severe sepsis or septic shock

Description

Inclusion Criteria:

To be eligible patients must have all of the following:

• Must be admitted or transferred to either the ED or an Intensive Care Unit.
• Have a high clinical suspicion of an infection
• Have sepsis as defined by an infection together with two or more SIRS criteria
• Evidence of acute organ dysfunction and/or Shock.

Exclusion Criteria:

• Patients less than 18 years of age
• Patients in whom the sepsis has been present from before the beginning of the study period
• Any patients previously included in the study during the same study period

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
28-Day Mortality	one week

Secondary Outcome Measures

Outcome Measure	Time Frame
Organ Failure	one week

Other Outcome Measures

Outcome Measure	Time Frame
Length of Stay in the Hospital	one week

Collaborators and Investigators

• Sponsor: European Society of Intensive Care Medicine
• Collaborators: Society of Critical Care Medicine (SCCM)
• Investigators: Principal Investigator: Andrew RHODES, MD, PhD, European Society of Intensive Care Medicine

Publications and helpful links

Helpful Links

• Related Info

Study record dates

Study Major Dates

• Study Start: November 1, 2013
• Primary Completion (Actual): November 1, 2013
• Study Completion (Actual): January 1, 2014

Study Registration Dates

• First Submitted: September 12, 2013
• First Submitted That Met QC Criteria: September 16, 2013
• First Posted (Estimate): September 17, 2013

Study Record Updates

• Last Update Posted (Estimate): August 20, 2014
• Last Update Submitted That Met QC Criteria: August 19, 2014
• Last Verified: August 1, 2014

More Information

Terms related to this study

• Keywords: septic shock; infection; sepsis; organ dysfunction; severe sepsis; quality improvement
• Additional Relevant MeSH Terms: Pathologic Processes; Infections; Systemic Inflammatory Response Syndrome; Inflammation; Shock; Sepsis; Toxemia; Shock, Septic
• Other Study ID Numbers: ImPRESS