Clinical Trials on Coagulation Defect; Acquired

Total 10417 results

Universiti Putra Malaysia

Completed

Effect of Resistance Training in Water Combined With Land on Starting and Turning ,12-weeks Resistance Training

Resistance, APC

China
Hoffmann-La Roche
Chugai Pharmaceutical

Completed

A Study of Emicizumab Administered Subcutaneously (SC) in Pediatric Participants With Hemophilia A and Factor VIII (FVIII) Inhibitors (HAVEN 2)

Hemophilia A

United States, France, Germany, Italy, South Africa, Spain, Turkey, Japan, United Kingdom, Costa Rica
Baxalta now part of Shire

Completed

BAX 826 Dose-Escalation Safety Study

Hemophilia A

Spain, Bulgaria, Germany, United Kingdom, Italy, Poland, Russian Federation, Netherlands, Hungary
Baxalta now part of Shire
Baxalta Innovations GmbH, now part of Shire

Completed

BAX 855 PK-guided Dosing (PROPEL)

Hemophilia A

Spain, United States, Australia, Singapore, Taiwan, Hong Kong, Malaysia, Bulgaria, United Kingdom, Switzerland, Ukraine, Turkey, Italy, Norway, France, Austria, Romania, Sweden, Poland, Germany, Hungary, Israel
Baxalta now part of Shire

Completed

Phase 3 Efficacy and Safety Study of BAX 855 in Severe Hemophilia A Patients Undergoing Surgical Procedures

Hemophilia A

United States, Spain, Netherlands, United Kingdom, Bulgaria, Lithuania, Russian Federation, Switzerland, Ukraine
Baxalta now part of Shire
Baxter Innovations GmbH

Terminated

Early Prophylaxis Immunologic Challenge (EPIC) Study (EPIC)

Hemophilia A

Poland, United States, Bulgaria, Serbia, Canada, Russian Federation, Germany, Netherlands, Lithuania, Czechia, Austria, Spain
Baxalta now part of Shire

Completed

Efficacy and Safety Study of a Recombinant Protein-Free Manufactured Factor VIII (rAHF-PFM) in Previously Untreated Hemophilia A Patients

Hemophilia A

United States, France, United Kingdom, Spain, Germany, Canada, Puerto Rico, Italy, Sweden, Austria
Baxalta now part of Shire

Completed

Pharmacokinetic Study of ADVATE 3000 IU in Previously Treated Patients With Severe Hemophilia A

Hemophilia A

Bulgaria, Russian Federation
Baxalta now part of Shire

Completed

Prophylaxis Study of Recombinant Factor VIII Manufactured Protein-Free (rAHF-PFM) in Patients With Hemophilia A

Hemophilia A

United States, Poland, Slovenia, Greece, Russian Federation, Hungary, Italy, United Kingdom, Czechia, Austria
Baxalta now part of Shire

Completed

Efficacy and Safety Study of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Pediatric Patients in Canada With Hemophilia A - A Continuation of Baxter Study 060101

Hemophilia A

Canada
Baxalta now part of Shire
Baxter Innovations GmbH

Completed

BAX 855 Dose-Escalation Safety Study

Hemophilia A

Japan, Bulgaria, Germany, United Kingdom
Baxalta now part of Shire

Completed

China ADVATE PTP Study

Hemophilia A

China
Baxalta now part of Shire

Completed

Retrospective Chart Review to Evaluate Safety and Tolerability of ADVATE Among Previously Untreated Patients in China With Moderate to Severe Hemophilia A

Hemophilia A

China
Boston VA Research Institute, Inc.
University of Michigan; Emory University; Shire

Withdrawn

Improved Factor VIII Inhibitor Evaluation (IFIE)

Hemophilia A | Hemophilia

United States
The University of Texas Health Science Center,...
Baxter Healthcare Corporation; Rho, Inc.

Completed

Hemophilia Inhibitor Previously Untreated Patient Study (HIPS)

Hemophilia A

United States, Austria, Italy, Netherlands, Sweden
Assistance Publique - Hôpitaux de Paris
Baxter Healthcare Corporation

Terminated

PK Driven Prophylaxis for Hemophilia A (OBTC)

Hemophilia A

France
Catholic University of the Sacred Heart

Unknown

PHYSICAL ACTIVITY AND FVIII CLEARANCE: RELEVANCE FOR PERSONALIZED THERAPY IN SEVERE HAEMOPHILIA A (PHYSEMO) (PHYSEMO)

Hemophilia A

Italy
Sinocelltech Ltd.

Unknown

Safety,Efficacy and Pharmacokinetics Evaluation of SCT800 in Previously Treated Paediatric Patients With Severe Haemophilia A.

Hemophilia A
Children's Hospital Los Angeles

Completed

Individualizing Hemophilia Prophylaxis Using Thromboelastography

Hemophilia A

United States
Lund University
Shire

Completed

Evaluation of a Standardized Protocol for Thrombin Generation Assay

Hemophilia A

Sweden
Bayer

Completed

Evaluation of Patient and Physician Reported Reasons for Switching Factor VIII Replacement Therapies (PARkER)

Hemophilia A

United States
Emory University

Completed

Characterization of Laboratory Response to DDAVP in Adult Hemophilia A Carriers

Hemophilia A

United States
Genentech, Inc.

Approved for marketing

An Expanded Access Program of Emicizumab in Participants With Hemophilia A With Inhibitors

Hemophilia A

United States
CSL Behring

Terminated

Study of Biostate for Treatment of Children With Hemophilia A Complicated by Antibody Development

Hemophilia A

Russian Federation, Germany, Italy, Austria, Greece
Pfizer

Completed

Study Evaluating On-Demand Treatment Of Xyntha In Chinese Subjects

Hemophilia A

China
Sinocelltech Ltd.

Unknown

Pharmacokinetic Study of SCT800 in Previously Treated Patients With Hemophilia A

Hemophilia A

China
CSL Behring

Completed

An Open-label Safety, Efficacy and Pharmacokinetic Study of a Recombinant FVIII Compared to Recombinant Human Antihemophilic FVIII in Patients With Severe Hemophilia A

Hemophilia A

United States, Australia, Austria, Canada, Czech Republic, Germany, Hungary, Italy, Japan, Lebanon, Malaysia, Netherlands, Philippines, Poland, Romania, Russian Federation, South Africa, Spain, Ukraine, United Kingdom
Centre Hospitalier Universitaire de Saint Etienne
Pfizer

Completed

Tissue Factor Pathway Inhibitor (TFPI) and Haemorrhagic Manifestations in Haemophilia A and B Patients

Hemophilia

France
Bayer

Completed

Single Dose Study in Subjects With Severe Hemophilia A Comparing Pharmacokinetic Parameters for BAY81-8973 and Advate

Hemophilia A

Bulgaria
Pfizer

Completed

Post Marketing Surveillance To Observe Safety And Efficacy Of Xyntha® In Subjects With Hemophilia A

Hemophilia A

Korea, Republic of
Bayer

Completed

Retrospective Study in Chinese Pediatric Hemophilia A Patients With rFⅧ Contained Regular Prophylaxis (ReCARE)

Hemophilia A

China
University Hospital, Montpellier
Centre Hospitalier Universitaire de Saint Etienne; University Hospital, Clermont-Ferrand and other collaborators

Withdrawn

Non Neutralizing Antibodies: Prevalence and Characterization

Hemophilia A

France
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating ReFacto in Hemophilia A

Hemophilia A
Sheba Medical Center

Completed

Combination Therapy of Low Doses of rFVIIa and FEIBA for Severe Hemophilia A Patients With an Inhibitor to Factor VIII

Hemophilia A
Victor J Marder, M.D.
Baxter Healthcare Corporation

Unknown

Personalized Prediction of Tolerance and Immunogenicity in Hemophilia (PPTIH)

Hemophilia A

United States
Bayer

Completed

EffeKt Taiwan- Efficacy and Safety of Long-term Treatment With KOGENATE® FS in Taiwan

Hemophilia A

Taiwan
CSL Behring

Completed

A Study of the Use of Factor XIII Concentrate in Patients With Inherited FXIII Deficiency

Factor XIII Deficiency

United States, Spain
Bayer

Completed

International PMS Study - KOGENATE Bayer

Hemophilia A

Switzerland, France, Spain, Sweden, Austria, Italy, Belgium, Denmark, Greece, Netherlands
Medical University of Vienna

Completed

Recombinant Factor VIIa (NovoSeven) on Restoring Coagulation Activation

Hemophilia A

Austria
University of Aarhus

Completed

Clot Formation and Clot Stability in Patients With Severe Haemophilia A

Hemophilia A

Denmark
University of Cologne

Recruiting

Retrospective Analysis of the Efficiency of Caplacizumab in the Treatment of aTTP (REACT-2020)

Acquired Thrombotic Thrombocytopenic Purpura

Germany
Guerbet

Completed

Efficacy and Safety of Gadopiclenol for Central Nervous System (CNS) Magnetic Resonance Imaging (MRI) (PICTURE)

Blood Brain Barrier Defect | CNS Lesion

United States, Spain, Korea, Republic of, Taiwan, France, Hungary, Belgium, Germany, Italy, Mexico, Poland
Hospices Civils de Lyon

Recruiting

Efficiency of 3D-printed Implant Versus Autograft for Orbital Reconstruction (TOR-3D) (TOR-3D)

Significant Bone Defect in the Orbit

France
Mahidol University
Wolf Schleinzer Stiftung zur Wissenschafts- und Bildungsförderung, Germany

Completed

Immunomodulation Effect of Blood Transfusion

Surgery | Immune Defect | Incompatible Blood Transfusion

Thailand
The Second Hospital of Tangshan
Chinese PLA General Hospital

Completed

Treatment of Soft Tissue Loss With Nerve Defect in the Finger Using the Boomerang Nerve Flap

Soft Tissue Loss With Nerve Defect
Centre Hospitalier Universitaire, Amiens
University Hospital, Lille; Nantes University Hospital; Centre Hospitalier Charles... and other collaborators

Recruiting

Clinical Efficacy and Long Term Effects of Transcranial Direct Current Stimulation (tDCS) in Children With Attention Deficit/Hyperactivity Disorder (ADHD) (STIMADHD)

Attention Deficit Hyperactivity Disorder | Transcranial Direct Current Stimulation

France
Spark Therapeutics

Completed

Lead-in Study to Collect Prospective Efficacy and Safety Data of Current FVIII Prophylaxis Replacement Therapy in Adult Hemophilia A Participants

Hematologic Diseases | Hemophilia A | Blood Coagulation Disorders, Inherited | Coagulation Protein Disorders | Hemorrhagic Disorders | Genetic Diseases, Inborn | Genetic Diseases, X-Linked | Blood Coagulation Disorder | Factor VIII Deficiency

United States, Australia, Thailand, Canada
Mayo Clinic

Completed

Coagulation Test Changes Associated With Acute Normovolemic Hemodilution in Cardiac Surgery

Bleeding | Coagulation Disorder

United States
University of Nove de Julho

Unknown

Effects of Photobiomodulation on Superficial Sensitivity and Muscle Activity of Individuals With Myelomeningocele

Motor Activity | Myelomeningocele Without Hydrocephalus | Sensory Defect
Centre Hospitalier Universitaire Vaudois
Lee Ann LAURENT APPLEGATE; Virginie PHILIPPE

Not yet recruiting

Study Comparing Two Methods for the Treatment of Large Chondral and Osteochondral Defects of the Knee

Chondral Defect | Articular Cartilage Defect | Osteochondritis

Switzerland

Clinical Trials on Coagulation Defect; Acquired

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