Clinical Trials on Cocaine Abuse and Dependence in United States

Total 2362 results

University of Pennsylvania

Completed

A Phase II Trial of Varenicline for the Treatment of Cocaine Dependence

Cocaine Dependence

United States
Baylor College of Medicine
National Institute on Drug Abuse (NIDA)

Completed

Pharmacogenetics of Doxazosin for Cocaine Dependence

Cocaine Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Terminated

The Effect of Brief Potent Glutamatergic Modulation on Cocaine Dependence

Cocaine Dependence

United States
New York State Psychiatric Institute

Completed

Glutamatergic Modulation of Cocaine-related Deficits

Cocaine Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Open-Label Pilot Study of Lisdexamfetamine for Cocaine Dependence (Vyvance)

Cocaine Dependence

United States
Biotie Therapies Inc.
National Institute on Drug Abuse (NIDA)

Completed

Study of Safety and Potential Efficacy of SYN117 in Cocaine Dependent Volunteers

Cocaine Dependence

United States
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA)

Completed

Carbidopa/Levodopa Combined With Behavioral Therapy for the Treatment of Cocaine Dependence

Cocaine Dependence

United States
Massachusetts General Hospital
Janssen, LP

Completed

Study of the Effects of Risperdal Consta on Brain Reward Circuitry Function, Craving and Cocaine Use in Active Cocaine Dependence

Cocaine Dependence

United States
New York State Psychiatric Institute
Novel Cocaine Pharmacotherapies

Terminated

Effects of Vigabatrin on Cocaine Self-Administration

Cocaine Dependence

United States
University of Pennsylvania

Withdrawn

A Study of Baclofen ER (CURE)

Cocaine Dependence

United States
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA)

Completed

Behavioral Incentives to Increase Exercise in Cocaine Dependent Women

Cocaine Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Progesterone Treatment for Cocaine-dependent Women: A Pilot Study (PROG)

Cocaine Dependence

United States
UConn Health
National Institute on Drug Abuse (NIDA)

Completed

Prize Contingency Management for Cocaine-Dependent Methadone Patients

Cocaine Abuse

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Effects of Aripiprazole on Cocaine Craving and Self-Administration

Cocaine Abuse

United States
National Institute on Drug Abuse (NIDA)
University of Texas

Terminated

Interaction Between Vanoxerine (GBR 12909) and Cocaine in Cocaine Dependent Individuals

Cocaine-Related Disorders | Cocaine Abuse

United States
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA); University of Texas

Completed

Behavioral Therapy Combined With Carbidopa/Levodopa for the Treatment of Cocaine Dependence

Cocaine-Related Disorders | Cocaine Abuse

United States
Weill Medical College of Cornell University
National Institute on Drug Abuse (NIDA)

Recruiting

Safety Study of a Disrupted Adenovirus (Ad) Serotype Cocaine Vaccine for Cocaine-dependent Individuals

Cocaine Dependence

United States
Boston University

Completed

Efficacy of Mirtazapine in Depressed Cocaine Dependent Subjects

Depression | Cocaine Dependence

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

GLP-1 Agonism for Blocking Cocaine Euphoria and Self-Administration

Cocaine Dependence

United States
Yale University

Completed

Validation of a Remote Wireless Sensor Network (WSN) Approach to the Individualized Detection of Cocaine Use in Humans

Cocaine Dependence

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Behavioral Treatment for Cocaine Dependent Women

Cocaine Dependence

United States
Medical University of South Carolina

Completed

Gender Differences in Response to Cues in Cocaine Dependence

Cocaine Dependence

United States
Yale University

Completed

Modafinil, Sleep Architecture and Cocaine Relapse

Cocaine Dependence

United States
Midwest Biomedical Research Foundation

Withdrawn

Tacrine Effects on Cocaine Self-Administration and Pharmacokinetics

Cocaine Dependence

United States
University of Arkansas
National Institute on Drug Abuse (NIDA)

Completed

Disulfiram for Cocaine Abuse

Cocaine Dependence

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Computer-Based Training in Cognitive Behavior Therapy (CBT4CBT)

Cocaine Abuse

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Multicenter Trial of Combined Pharmacotherapy to Treat Cocaine Dependence (TACT2)

Cocaine Dependence

United States
National Institute on Drug Abuse (NIDA)

Withdrawn

Psychology of Reward and Punishment: Functional and Molecular Brain Imaging and Monoaminergic Correlates

Cocaine Abuse | Cocaine Addiction

United States
Temple University
Medical University of South Carolina; University of Pennsylvania; Research Foundation...

Active, not recruiting

Clavulanic Acid for the Treatment of Cocaine Use Disorder

Cocaine Dependence

United States
Embera NeuroTherapeutics, Inc.

Completed

A Placebo-Controlled Study of a Combination of Metyrapone and Oxazepam in Cocaine Addiction

Cocaine Dependence | Cocaine Addiction

United States
Medical University of South Carolina

Completed

Longitudinal Assessment of Functional Connectivity in Treatment Engaged Cocaine Users

Substance Use Disorders | Cocaine Dependence

United States
University of Pennsylvania

Completed

Adaptive Treatment for Alcohol and Cocaine Dependence

Substance Use Disorders

United States
National Institute on Drug Abuse (NIDA)

Completed

Serotonin, Impulsivity, and Cocaine Dependence Treatment

Cocaine Dependence

United States
US Department of Veterans Affairs

Terminated

Prazosin for ETOH or Cocaine Craving

Alcoholism | Cocaine Dependence

United States
Baylor College of Medicine
National Institute on Drug Abuse (NIDA); Johns Hopkins University; University... and other collaborators

Completed

Multisite Controlled Trial of Cocaine Vaccine (TA-CD)

Cocaine Dependence

United States
Temple University
National Institute on Drug Abuse (NIDA); University of Pennsylvania; Beth Israel...

Completed

Pharmaco-Magnetic Resonance Spectroscopy (MRS) Study of Clavulanic Acid

Cocaine Dependence

United States
Yale University
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

FMRI of Stress and Addictive Disorders

Alcoholism | Opioid Dependence | Cocaine Dependence | Adolescents | Pathological Gamblers

United States
New York State Psychiatric Institute

Completed

Investigation of Mifepristone (RU486) on Stress Sensitivity and Relapse Prevention in Cocaine Dependent Patients

Cocaine Dependence

United States
University of Texas Southwestern Medical Center
National Institute on Drug Abuse (NIDA); Dallas VA Medical Center

Completed

Impulsivity, Neural Deficits and Cocaine Addiction

Cocaine Dependence

United States
Massachusetts General Hospital

Completed

Development and Testing of Adolescent Twelve-Step Facilitation

Alcohol Dependence | Drug Abuse | Alcohol Abuse | Drug Dependence

United States
Yale University
National Institute of Mental Health (NIMH)

Completed

Impulsivity and Stimulant Administration

Cocaine Dependence | Impulsivity

United States
University of Miami
National Institute on Drug Abuse (NIDA)

Completed

Valproate Efficacy in Cocaine-Bipolar Comorbidity

Bipolar Disorder | Cocaine Dependence

United States
Catalyst Pharmaceuticals, Inc.

Completed

Vigabatrin for Treatment of Cocaine Dependence

Cocaine Dependence

United States
Yale University

Terminated

Establishing and Eliminating Cue-drug Associations in Human Cocaine Addiction

Cocaine Dependent Subjects

United States
University of California, Los Angeles
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Completed

Cocaine Use Reduction With Buprenorphine (CURB)

Cocaine Dependence

United States
National Institute on Drug Abuse (NIDA)

Completed

A Multi-Center Trial of Nepicastat for Cocaine Dependence

Cocaine Dependence

United States
University of Washington
U.S. Army Medical Research and Development Command

Completed

Efficacy Trial of Warrior Check-Up

Alcohol Dependence | Substance Abuse | Alcohol Abuse | Substance Dependence

United States
Kyle Kampman
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Topiramate for Alcohol and Cocaine Dependence (TOP2)

Alcoholism | Cocaine Dependence

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Terminated

Vigabatrin for Cocaine and Alcohol Dependence (VGB)

Alcoholism | Cocaine Dependence

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence - 1

Alcoholism | Cocaine Dependence

United States

Clinical Trials on Cocaine Abuse and Dependence in United States

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Rare Diseases

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