Clinical Trials on Cognitive Impairment in Germany

Total 276 results

Novartis Pharmaceuticals

Completed

An Open-label, Parallel-group Study to Determine the Pharmacokinetics of a Single Dose of AFQ056 in Subjects With Renal Impairment Compared to Healthy Subjects

Mild Moderate | or Severe Renal Impairment

Germany
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Effect of Hepatic Impairment on M2951 (BTK Inhibitor) PK

Hepatic Impairment

Germany
Janssen Sciences Ireland UC

Completed

A Study to Evaluate the Effect of Hepatic Impairment on JNJ-56136379

Hepatic Impairment

Germany
Novartis Pharmaceuticals

Completed

Impact of Hepatic Impairment on the Pharmacokinetics of Deferasirox.

Hepatic Impairment

Germany
Poxel SA

Completed

Pharmacokinetics of Imeglimin in Hepatic Impaired Subjects

Hepatic Impairment

Germany
Janssen Sciences Ireland UC

Completed

A Study to Evaluate the Effect of Hepatic Impairment on JNJ-73763989

Hepatic Impairment

Germany
H. Lundbeck A/S

Completed

Study Investigating the Pharmacokinetic Properties of the Drug Lu AF35700 in Subjects With Liver Impairment and in Healthy Subjects

Hepatic Impairment

Germany
Novartis Pharmaceuticals

Completed

A Study of LCZ696 in Subjects With Mild and Moderate Hepatic Impairment Compared With Normal Healthy Volunteers

Hepatic Impairment

Germany
Newron Pharmaceuticals SPA

Completed

A Study to Assess the Effect of Hepatic Impairment on Safinamide Pharmacokinetics

Hepatic Impairment

Germany
H. Lundbeck A/S

Completed

Efficacy of Vortioxetine on Cognitive Dysfunction in Working Patients With Major Depressive Disorder

Major Depressive Disorder

Finland, Germany, Estonia, Lithuania
Janssen-Cilag International NV

Completed

A Study of Orally Administered Pimodivir in Adult Participants With Hepatic Impairment

Hepatic Impairment

Germany
Janssen Research & Development, LLC

Terminated

A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Erdafitinib

Hepatic Impairment

Germany
University Hospital Tuebingen

Completed

Studying Cognition in SPG4

Cognitive Impairment | Hereditary Spastic Paraplegia

Germany
Idorsia Pharmaceuticals Ltd.

Completed

The Effect of Reduced Liver Function on Selatogrel Pharmacokinetics

Healthy Subjects | Hepatic Impairment

Germany
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Hepatic Impairment on Lazertinib (JNJ-73841937)

Healthy | Hepatic Impairment

Germany
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Hepatic Impairment on JNJ-42847922 in Adult Participants

Healthy | Hepatic Impairment

Germany
H. Lundbeck A/S

Completed

Efficacy of Vortioxetine on Cognitive Dysfunction in Patients With Partial or Full Remission of Major Depressive Disorder

Major Depressive Disorder

Finland, Germany, Serbia, Slovakia, Estonia
VectivBio AG

Completed

A Phase 1, Open-Label Evaluation of the Pharmacokinetics and Safety of a Single Dose of Apraglutide in Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment

Germany, Slovakia
LG Life Sciences

Completed

Influence of Hepatic Impairment on Pharmacokinetic (PK) and Pharmacodynamic (PD) of Gemigliptin PK and PD After Multiple Oral Doses in Healthy White Volunteers

Hepatic Impairment

Germany
Novartis Pharmaceuticals

Completed

Pharmacokinetics of LCZ696 in Subjects With Mild and Moderate Renal Impairment Compared to Healthy Subjects With Normal Renal Function

Mild and Moderate Renal Impairment

Russian Federation, Germany, Serbia
FORUM Pharmaceuticals Inc
Syneos Health; NeuroCog Trials, Inc.

Completed

Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy

Schizophrenia | Impaired Cognition

United States, Australia, Poland, Ukraine, Germany, Spain, Argentina, Serbia, Canada, Singapore, Russian Federation, Brazil, Mexico
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Behaves in Participants With Reduced Liver Function and in Healthy Participants With Normal Liver Function

Hepatic Impairment

Germany, Slovakia
Novartis Pharmaceuticals

Completed

Pharmacokinetics of RLX030 in Subjects With Mild, Moderate and Severe Hepatic Impairment Compared to Healthy Subjects

Hepatic Impairment

Germany, Russian Federation
University of Pennsylvania
Charite University, Berlin, Germany; DLR German Aerospace Center; National Aeronautics...

Enrolling by invitation

Effects of Long-Duration Spaceflight on General and Spatial Cognition and Its Neural Basis

Cognitive Performance | Brain Structure

United States, Germany
FORUM Pharmaceuticals Inc
Syneos Health

Completed

A 26-Week Extension Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy

Schizophrenia | Impaired Cognition

United States, Ukraine, United Kingdom, Germany, Spain, Argentina, Canada, Singapore, Russian Federation, Italy, Mexico, Colombia, Australia, Belgium, Poland, Romania
Novartis Pharmaceuticals

Withdrawn

Systemic VEGF Protein Dynamics Following Intravitreal Injections of Ranibizumab Versus Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (TIDE DME)

Visual Impairment Due to Diabetic Macular Edema

Germany
Schön Klinik Berchtesgadener Land
European Respiratory Society

Completed

pCO2 Oscillations During Exercise: Relation to Cerebral Blood Flow and to Cognitive Dysfunction in COPD

Chronic Obstructive Pulmonary Disease

Germany
Novartis Pharmaceuticals

Completed

Pharmacokinetic Study of BKM120 in Subjects With Hepatic Impairment

Hepatic Impairment

Germany, Russian Federation, Bulgaria
Janssen Infectious Diseases BVBA

Completed

A Study to Assess Safety and Pharmacokinetics of Telaprevir in Patients With Hepatic Impairment

Hepatic Impairment

Germany, Czech Republic
Charite University, Berlin, Germany
Arda Can Cetindag; Lukas Preis

Withdrawn

The Importance of Sleep Quality and the Blood-brain Barrier in Cognitive Disorders and Alzheimer's Disease

Alzheimer Disease | Sleep Apnea | Sleep Deprivation | Blood Brain Barrier Defect

Germany
University Medical Center Groningen
University of Sao Paulo; Dokkyo Medical University; Somogy Megyei Kaposi Mór... and other collaborators

Unknown

Beam Walking Across the Lifespan for Falls Prediction (BEAM)

Stroke | Parkinson Disease | Cognitive Impairment | Dementia | Aging | Postural; Defect | Diagnoses Disease

Netherlands, Brazil, Germany, Hungary, Japan
RWTH Aachen University

Completed

Improved Orthostatic Tolerance = Better Cognitive Function in Parkinson's Disease (PaKogOH)

Parkinson Disease | Cognitive Impairment | Hypotension, Orthostatic | Autonomic Failure

Germany
Novartis Pharmaceuticals

Completed

A Study to Evaluate the Pharmacokinetics of AFQ056 in Subjects With Hepatic Impairment Compared to Healthy Subjects

Hepatic Impairment

Germany, United States, Hungary
Merck KGaA, Darmstadt, Germany

Completed

Effect of Renal Impairment on Evobrutinib Pharmacokinetics (PK)

Renal Impairment

Germany
Nycomed
NPS Pharma

Completed

Pharmacokinetics of 10 mg Teduglutide in Subjects With Renal Impairment Compared to Healthy Subjects With Normal Renal Function

Renal Impairment

Germany
AstraZeneca

Completed

Safety Study of AZD5672 in Renally Impaired Subjects

Renal Impairment

Germany
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate ID-085 in People With Mild, Moderate, and Severe Kidney Disease

Renal Impairment

Germany
Polyphor Ltd.

Completed

Pharmacokinetics and Safety of POL7080 in Patients With Renal Impairment

Renal Impairment

Germany
Sanofi

Completed

Pharmacokinetic and Tolerability Study of 14 mg Single Dose of Teriflunomide in Subjects With Severe Renal Impairment

Renal Impairment

Germany
H. Lundbeck A/S

Completed

Pharmacokinetic Properties of Nalmefene in Subjects With Renal Impairment and in Healthy Subjects

Renal Impairment

Germany
Galapagos NV

Completed

Study to Evaluate GLPG0634 in Subjects With Renal Impairment Compared to Healthy Subjects

Renal Impairment

Germany
University Hospital Schleswig-Holstein

Completed

Incidence and Prevention of Hypothermia in Newborns Bonding During Caesarean Section (THER5)

Hypothermia | Postoperative Shivering | Thermoregulation Impairment

Germany
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Pharmacokinetics of ACT-1014-6470 in Subjects With Severe Renal Impairment Compared to Control Subjects

Healthy

Germany
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

Germany, Poland, Slovakia
Idorsia Pharmaceuticals Ltd.

Completed

The Effect of Hepatic Impairment on Aprocitentan Pharmacokinetics

Healthy Subjects | Hepatic Impairment

Germany, Poland
University Medicine Greifswald

Completed

Effects of tDCS on Social Cognition in Aging (SoCoStim)

Aging | Social Cognition

Germany
Janssen Pharmaceutica N.V., Belgium

Terminated

A Study to Evaluate the Effect of Renal Impairment on JNJ-64417184 and Its Two Minor Metabolites JNJ-68294291 and JNJ-65201526 in Adult Participants

Renal Impairment

Germany
H. Lundbeck A/S

Terminated

Pharmacokinetics of Lu AF35700 in Subjects With Renal Impairment

Renal Failure

Germany
Merck KGaA, Darmstadt, Germany

Completed

Pharmacokinetics in Subjects With Renal Impairment

Renal Impairment

Germany
Universitätsklinikum Hamburg-Eppendorf
European Union

Completed

Effects of Infra- and Ultrasound on the Brain

Depression | Sleep | Well-being | Cognitive Function | Ultrasound | Brain Function

Germany

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