Clinical Trials on Colorectal and Ileorectal Anastomosis

Total 4545 results

Jiangsu HengRui Medicine Co., Ltd.
Sun Yat-sen University; Peking University Cancer Hospital & Institute

Completed

A Study of Famitinib in Patients With Advanced Colorectal Cancer

Colorectal Cancer | Colorectal Cancer Metastatic | Colorectal Cancer Recurrent

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Panitumumab With or Without Trametinib in Treating Patients With Stage IV Colorectal Cancer

EGFR NP_005219.2:p.S492R | KRAS Gene Mutation | MAP2K1 Gene Mutation | Metastatic Colorectal Adenocarcinoma | Refractory Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7

United States
Central Hospital, Nancy, France

Completed

Post-operative CRP Trend After Ileocolic Resection in Crohn's Disease Patients.

Crohn Disease

France
Weill Medical College of Cornell University
AstraZeneca

Withdrawn

Study of Proton Pump Inhibitors (PPI) to Prevent Strictures After Gastric Bypass Surgery

Morbid Obesity | Anastomotic Stricture

United States
National Cancer Institute (NCI)

Recruiting

Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver

Colorectal Cancer | Liver Metastases | Colorectal Carcinoma | Colorectal Adenocarcinoma | Colorectal Cancer With Hepatic Metastases

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer

Progressive Disease | Recurrent Colorectal Carcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer... and other conditions

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Celecoxib, Recombinant Interferon Alfa-2b, and Rintatolimod in Treating Patients With Colorectal Cancer Metastatic to the Liver

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Metastatic Carcinoma in the Liver

United States
Hospital Donostia

Recruiting

Incidence of Acute Urine Retention: Randomized Clinical Trial Comparing Early, Mid or Late Urinary Catheter Removal in Patients With Rectal Resection (RAOREC)

Rectal Cancer | Urinary Tract Infections | Anastomotic Leak | Surgical Site Infection | Retention, Urinary

Spain
University Hospital, Ghent

Completed

Assessment of the Blink (First) Impression Regarding the Presence of Cancer Within Colorectal Polyps

Colorectal Cancer | Colorectal Polyp | Colono

Belgium
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Liver Surgery and Chemotherapy in Treating Patients With Colorectal Cancer With Liver Metastases That Can Be Removed by Surgery and Lung Metastases That Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Metastatic Malignant Neoplasm in the Lung | Resectable Colorectal Carcinoma

United States
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Combination Chemotherapy, Bevacizumab, and/or Atezolizumab in Treating Patients With Deficient DNA Mismatch Repair Metastatic Colorectal Cancer, the COMMIT Study

Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v7

United States
Hospital Universitario La Fe

Unknown

Mu Opioid Receptor 1 Expression and Activation Patterns in Colorectal Cancer

Colorectal Surgery for Stage II / III Primary Colorectal Cancer
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Refractory Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8

United States
Mirati Therapeutics Inc.

Active, not recruiting

Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10)

Metastatic Colorectal Cancer | Advanced Colorectal Cancer

United States, Denmark, Finland, Italy, Spain, Belgium, Romania, Taiwan, Thailand, France, Germany, Korea, Republic of, China, Malaysia, Hong Kong, Australia, Austria, Puerto Rico, Singapore, Canada, Portugal, Poland, Greece, United Kingdom and more
University College, London
AstraZeneca; Cancer Research UK; National Institute for Health Research, United...

Completed

Phase I/II Trial of Antagonism of HER in GI Cancer (PANTHER)

Metastatic Colorectal Cancer | Recurrent Colorectal Cancer

United Kingdom
Sidney Kimmel Comprehensive Cancer Center at Johns...
Merck Sharp & Dohme LLC

Completed

Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors (Cohorts A, B and C)

MSI Positive Colorectal Cancer | MSI Negative Colorectal Cancer | MSI Positive Non-Colorectal Cancers

United States
National Cancer Institute (NCI)

Completed

A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination With Immune Checkpoint Inhibition in Refractory Colorectal Cancer

Colorectal Neoplasms | Colorectal Cancer | Colorectal Carcinoma | Colorectal Adenocarcinoma | Refractory Cancer

United States
University of Chicago

Active, not recruiting

Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis

Colorectal Cancer Metastatic | Colorectal Cancer Stage IV | Appendix Cancer | Colorectal Cancer, Genetics of

United States
Shandong University

Completed

Association Between Confocal Laser Endomicroscopic (CLE) Features and Colorectal Mucosal Microbiome

Hyperplasia | Colorectal Neoplasia | Mucosal Microbiome | Colorectal Inflammation

China
University of Wisconsin, Madison

Completed

Survivorship Care Plan in Promoting Physical Activity in Breast or Colorectal Cancer Survivors in Wisconsin

Cancer Survivor | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Healthy Subject | Stage I Colorectal Cancer | Stage IIIA Colorectal Cancer | Stage IIIB Colorectal Cancer | Stage... and other conditions

United States
Janssen Research & Development, LLC

Completed

A Phase 3 Study to Evaluate Xilonix as an Anticancer Therapy in Patients With Symptomatic Colorectal Cancer

Advanced Colorectal Cancer | Symptomatic Colorectal Cancer | Colorectal Cancer With Cachexia

Poland
OncoAtlas LLC
N.N. Blokhin National Medical Research Center of Oncology; Moscow MultidisciplinaryClinical...

Recruiting

Dynamics of MSI and Genomic Profile of Colorectal Cancer In the Course of Immune Checkpoint Inhibitor Therapy (BLOOMSI)

Cancer | Colorectal Cancer | Colorectal Cancer Metastatic | Colon Adenocarcinoma | MSI-H Colorectal Cancer | dMMR Colorectal Cancer

Russian Federation
University of Dundee

Completed

Evaluation of Flexible Sigmoidoscopy Screening as an Adjunct to the National FOBT Screening Programme in Scotland

Colorectal Cancer | Colorectal Adenoma

United Kingdom
Shandong University

Completed

Molecular Imaging of Epidermal Growth Factor Receptor in Colorectal Neoplasia Using Confocal Laser Endomicroscopy

Colorectal Cancer | Colorectal Adenoma

China
Symphogen A/S

Terminated

Sym004 Versus Futuximab or Modotuximab in Patients With mCRC

Carcinoma | Metastatic Colorectal Cancer | Colorectal Cancer Metastatic

United States, Spain, Germany, Italy
South Tyneside and Sunderland NHS Foundation Trust
Medtronic; Newcastle University; North Wales Organisation for Randomised Trials...

Completed

COLO-DETECT: Can an Artificial Intelligence Device Increase Detection of Polyps During Colonoscopy?

Colonic Polyp | Colorectal Adenoma | Colorectal Polyp | Colorectal SSA | Colorectal Adenomatous Polyp | Sessile Serrated Adenoma | Sessile Colonic Polyp

United Kingdom
Copenhagen University Hospital, Hvidovre

Completed

Pathophysiology of Perioperative Fluid Management in Emergency Laparotomy

Anastomotic Leak | Fluid Overload | Intestinal Obstruction | Pathophysiology | Intestinal Perforation

Denmark
Peking University

Unknown

Prediction of Abdominal Complications After GastroEnterological Surgery (PACAGE)

Anastomotic Leak | Complication | Gastrointestinal Cancer

China
AHS Cancer Control Alberta
Cross Cancer Institute

Withdrawn

A Trial of Glutamine to Prevent Oxaliplatin Neurotoxicity and a Pharmacokinetic Analysis of Oxaliplatin

Colorectal Cancer | Metastasis | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal
Case Comprehensive Cancer Center

Recruiting

The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors

Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon | Stage III Colorectal Cancer | Stage I Colorectal Cancer | Stage II Colorectal Cancer

United States
Mainz Biomed

Not yet recruiting

Clinical Performance of the Mainz Biomed Colorectal Cancer Screening Test for Colorectal Cancer and Advanced Adenoma (reconAAsense)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenoma | Colorectal Polyp
Shandong University

Recruiting

Application of Hyperspectral Imaging Analysis Technology in the Diagnosis of Colorectal Cancer Based on Colonoscopic Biopsy

Colorectal Neoplasms | Colorectal Adenoma | Colorectal Polyp | Colorectal SSA

China
Sixth Affiliated Hospital, Sun Yat-sen University

Not yet recruiting

Fecal Metagenomics and Metabolomics Analyses to Identify Potential Screening Biomarkers for Colorectal Polyps and Cancer in Chinese Population

Colorectal Cancer | Gastrointestinal Microbiome | Colorectal Polyp | Mass Screening

China
University Hospital, Limoges

Recruiting

French Colorectal ESD Cohort in Experts Centers (FECCo)

Cancer Colorectal | Polyps Colorectal | Endoscopic Submucosal Resection

France
Roswell Park Cancer Institute
National Center for Advancing Translational Sciences (NCATS)

Recruiting

Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer

Recurrent Colorectal Carcinoma | Locally Advanced Colorectal Carcinoma | Stage III Colorectal Cancer

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma

United States
Fujian Cancer Hospital

Not yet recruiting

the Role of ctDNA in Predicting the Recurrence Risk of Colorectal Cancer

Colorectal Cancer Stage II | Colorectal Cancer Stage III
CellabMED
Yooyoung Pharmaceutical Co., Ltd.

Completed

To Evaluate the Safety, Tolerability, Pharmacokinetics and Antitumor Activity of YYB101 With Irinotecan, Patients Who Are Metastatic or Recurrent Colorectal Cancer Patients

Colorectal Cancer Metastatic | Colorectal Cancer Recurrent

Korea, Republic of
Emory University
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; National Institutes... and other collaborators

Completed

Pembrolizumab and XL888 in Patients With Advanced Gastrointestinal Cancer

Unresectable Pancreatic Carcinoma | Metastatic Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Recurrent Colorectal Carcinoma | Colorectal Adenocarcinoma | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVA Pancreatic... and other conditions

United States
Wuhan Union Hospital, China

Not yet recruiting

Molecular Study and Precision Medicine for Colorectal Cancer (MSPM)

Recurrent Colorectal Carcinoma | Advanced Colorectal Carcinoma

China
Sorlandet Hospital HF
Erasmus Medical Center; South-Eastern Norway Regional Health Authority; Maria...

Completed

Water Exchange Versus Carbon Dioxide for Colonoscopy

Pain | Colorectal Cancer | Colorectal Polyps | Colorectal Adenomas

Norway, Poland
Grupo Espanol Multidisciplinario del Cancer Digestivo
Amgen; Pivotal S.L.

Completed

FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status (OPALO)

Neoplasm Metastasis | Colorectal Neoplasms | Colorectal Cancer Metastatic | Colorectal Carcinoma

Spain
Symphogen A/S

Withdrawn

Sym004 Versus TAS-102 in Patients With mCRC

Carcinoma | Metastatic Colorectal Cancer | Colorectal Cancer Metastatic
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Endoscopic Vacuum Therapy for Transmural Defects in the Upper Gastrointestinal Tract

Anastomotic Leak | Esophageal Perforation | Endoscopic Vacuum Therapy | Esophageal Perforation, Traumatic | EsoSponge | VACStent

Netherlands
Shandong University

Completed

A New Quantitative Fecal Immunochemical Test in Detecting Colorectal Advanced Adenoma

Colorectal Cancer | Colorectal Neoplasm | Colorectal Adenoma

China
Cancer Prevention and Research Institute, Italy
Veneto Tumor Registry, Azienda Zero, Padua, Italy

Unknown

Adenoma Detection Rate With Endocuff-Assisted Colonoscopy - an Italian Trial (ITAvision)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenoma | Colorectal Polyp

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Tremelimumab and Durvalumab in Treating Patients With Colorectal Cancer With Liver Metastases That Can Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Carcinoma in the Liver | Resectable Mass

United States
Wuhan Union Hospital, China

Recruiting

A Single-Arm Phase II Exploratory Clinical Study of Pemigatinib in the Treatment of Advanced Gastric and Colorectal Cancer Patients With FGFR Alterations Who Have Failed Standard Therapy

Gastric and Colorectal Cancer

China
Children's National Research Institute

Completed

The Pharmacology and Hemodynamics of Dexmedetomidine in Children With Congenital Heart Disease

Atrial Septal Defect | Cardiac Transplant | Patent Ductus Arterious | Bidirectional Cavopulmonary Anastomosis

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-responders

Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Metastatic Small Intestinal Adenocarcinoma | Stage IV Small Intestinal Adenocarcinoma AJCC v8

United States

Clinical Trials on Colorectal and Ileorectal Anastomosis

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