Clinical Trials on Colorectal Carcinoma in United Kingdom

Total 13158 results

National Cancer Institute (NCI)

Completed

ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer

Colorectal Neoplasms | Colorectal Tumors | Colorectal Carcinoma

United States
Queen Mary University of London

Active, not recruiting

Cutaneous Squamous Cell Carcinoma Staging Study

Cutaneous Squamous Cell Carcinoma

United Kingdom
City of Hope Medical Center

Recruiting

Early Detection of Advanced Adenomas and Colorectal Cancer (AACRC)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Disorders | Colorectal Adenocarcinoma | Colorectal Cancer Stage II | Colorectal Cancer Stage III | Colorectal Cancer Stage IV | Colorectal Polyp | Colorectal Neoplasms Malignant | Colorectal Adenomatous Polyp | Colorectal Cancer Stage I | Colorectal Adenoma... and other conditions

United States, Italy, China, Spain, Japan
M.D. Anderson Cancer Center
National Cancer Institute (NCI); AstraZeneca

Active, not recruiting

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Refractory Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004

Colorectal Neoplasms | Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Colorectal Adenocarcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anticancer Drug, BAY 1895344, to the Usual Chemotherapy With FOLFIRI in Advanced or Metastatic Cancers of the Stomach and Intestines

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastroesophageal Junction Adenocarcinoma | Metastatic... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Metastatic Pancreatic Carcinoma | Refractory Malignant Solid Neoplasm | Refractory Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Unresectable Pancreatic Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Unresectable Malignant... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer

Progressive Disease | Recurrent Colorectal Carcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer... and other conditions

United States
Queen Mary University of London

Active, not recruiting

Enhanced Outcome Prediction in Cutaneous Squamous Cell Carcinoma Using Deep-learning and Computational Histopathology

Squamous Cell Carcinoma of the Skin

United Kingdom
National Health Service, United Kingdom

Recruiting

Trial Feasibility of Home Delivery of Colon Capsule Endoscopy Service With the Help of 5 G Technology (5GSUCCEEDS)

Colorectal Cancer | Colon Capsule Endoscopy

United Kingdom
University of Wisconsin, Madison
Merck Sharp & Dohme LLC

Completed

PI Pembro in Combination With Stereotactic Body Radiotherapy for Liver Metastatic Colorectal Cancer

Colorectal Cancer | Colorectal Adenocarcinoma | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | Metastatic Carcinoma in the Liver

United States
European Student Research Network

Completed

Acute PresentatiOn of CoLorectaL Cancer: an internatiOnal Snapshot (APOLLO)

Colorectal Cancer

United Kingdom
University of Edinburgh

Completed

Vitamin D Supplementation Study

Colorectal Cancer | Vitamin D Deficiency

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Effects of Serotonin Excess on Bone in Carcinoid Syndrome

Carcinoid Syndrome

United Kingdom
University of Warwick
Public Health England

Enrolling by invitation

Patient Outcomes From Second Film-readers and Test Threshold Relaxation in Breast Screening (POSTBOx)

Breast Cancer | Ductal Carcinoma in Situ

United Kingdom
North Tees and Hartlepool NHS Foundation Trust

Unknown

Single-port Versus Conventional Laparoscopic Colorectal Surgery

Colorectal Cancer | Inflammatory Bowel Disease | Diverticular Disease | Benign Colorectal Neoplasm

United Kingdom
Royal Marsden NHS Foundation Trust
Institute of Cancer Research, United Kingdom; Oracle Cancer Trust

Recruiting

Evaluation of Tongue Base MucOsectomy & Step sErial Sectioning (MOSES)

Squamous Cell Carcinoma of the Oropharynx

United Kingdom
Boston Scientific Corporation
Biocompatibles UK Ltd

Completed

Study of Chemoembolisation Using Irinotecan Bead Prior to Surgery in Metastatic Colorectal Cancer (PARAGON-II)

Metastatic Colorectal Cancer

United Kingdom, Austria, France
University of Utah
Novartis

Completed

RAD001, FOLFOX and Bevacizumab in Treatment of Colorectal Carcinoma

Colorectal Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Utomilumab, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8

United States
Ning Jin

Active, not recruiting

Riluzole in Combination With mFOLFOX6 and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8

United States
Sanofi

Completed

Real World Study on the Use of Cemiplimab in Adult Patients in UK (REACT-CEMI)

Cutaneous Squamous Cell Carcinoma

United Kingdom
Imperial College London
Incyte Biosciences UK Ltd

Active, not recruiting

Itacitinib in Advanced Hepatocellular Carcinoma (JAKaL)

Advanced Hepatocellular Carcinoma

United Kingdom
Roswell Park Cancer Institute
National Cancer Institute (NCI); Merck Sharp & Dohme LLC

Completed

Cetuximab and Pembrolizumab in Treating Patients With Colorectal Cancer That is Metastatic or Cannot Be Removed by Surgery

Recurrent Colorectal Carcinoma | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer

United States
University of Manchester

Completed

Healthy Eating and Active Lifestyle After Bowel Cancer: HEAL ABC (HEALABC)

Colorectal Cancer | Survivorship | Behavior, Health

United Kingdom
Memorial Sloan Kettering Cancer Center

Active, not recruiting

A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma

Colorectal Cancer | Cholangiocarcinoma

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Pemigatinib for the Treatment of Metastatic or Unresectable Colorectal Cancer Harboring FGFR Alterations

Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC v8 | Stage IIIC Colorectal Cancer AJCC v8 and other conditions

United States
York Teaching Hospitals NHS Foundation Trust

Completed

Pain Relief After Colorectal Surgery: Spinal Combined With Painbuster® vs Painbuster® Alone. (PROSP)

Colorectal Cancer

United Kingdom
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer

Recurrent Colorectal Carcinoma | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer

United States
Manchester University NHS Foundation Trust
University of Manchester; The Christie NHS Foundation Trust; Zenzium AI Ltd.; Aptus... and other collaborators

Recruiting

Enhanced Monitoring for Better Recovery and Cancer Experience in Greater Manchester (EMBRaCE-GM)

Colorectal Cancer | Lung Cancer | Hematological Cancer | CAR T-Cell Therapy

United Kingdom
NuCana plc

Recruiting

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

Melanoma | Renal Cell Carcinoma | Gastric Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Advanced Cancer | Head and Neck Squamous Cell Carcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Classical Hodgkin Lymphoma | Neoplasm Malignant | Pleural... and other conditions

United Kingdom
University of Aberdeen
NHS Grampian

Completed

The Improving Cancer Aftercare Study. (ICAS)

Colorectal Cancer | Prostate Cancer

United Kingdom
Novartis Pharmaceuticals

Recruiting

Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation (KontRASt-03)

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Colorectal Cancer | Non-Small Cell Lung Cancer | Nonsmall Cell Lung Cancer | Carcinoma, Non-Small Cell Lung | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal | Non-Small Cell Lung Carcinoma | KRAS G12C Mutant Solid Tumors

Korea, Republic of, Spain, Belgium, United States, France, Germany, Italy, Singapore
Novartis Pharmaceuticals

Completed

A Phase 1 Study Investigating the Combination of RAD001, Cetuximab and Irinotecan as Second-line Therapy After FOLFOX (or XELOX) Plus Bevacizumab in Patients With Metastatic Colorectal Cancer

Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal

United States
Bayer

Completed

Study to Develop a Prediction Model to Understand the Effect of Low-dose Aspirin on Cancer That Develops in the Colon and/or the Rectum, Diseases That Affects the Heart or Blood Vessels and Safety Outcomes in European Countries. The Study is Also Called PEACOS Model EU (PEACOCS)

Cardiovascular Disease | Colorectal Cancer | Bleeding

United Kingdom
Merck KGaA, Darmstadt, Germany

Completed

EMD 525797 in Colorectal and Ovarian Cancer Patients With Liver Metastases

Colorectal and Ovarian Cancer Patients With Liver Metastases

United Kingdom
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC; Institute of Cancer Research, United Kingdom

Terminated

PEmbrolizumab Combined With Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck (PEACH)

Squamous Cell Carcinoma of the Head and Neck | Squamous Cell Carcinoma

United Kingdom
Enzon Pharmaceuticals, Inc.

Unknown

A Study of EZN-2208 Administered With or Without Cetuximab in Patients With Metastatic Colorectal Carcinoma

Metastatic Colorectal Cancer

United States, Canada, Israel, Netherlands, United Kingdom
Terrence Jones
Nestlé

Completed

A Trial of Perioperative Immune Enhancing Feed in Patients Undergoing Surgery for Head and Neck Cancer (IMPACTHN)

Laryngeal Squamous Cell Carcinoma | Squamous Cell Carcinoma of Oropharynx | Squamous Cell Carcinoma of Mouth | Squamous Cell Carcinoma of the Hypopharynx

United Kingdom
National Cancer Institute (NCI)

Completed

A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination With Immune Checkpoint Inhibition in Refractory Colorectal Cancer

Colorectal Neoplasms | Colorectal Cancer | Colorectal Carcinoma | Colorectal Adenocarcinoma | Refractory Cancer

United States
South Tyneside and Sunderland NHS Foundation Trust
Newcastle University

Recruiting

COLO-COHORT (Colorectal Cancer Cohort) Study

Colorectal Cancer | Colorectal Neoplasm | Colorectal Adenoma | Predictive Cancer Model | Model

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust
Minimal Access Therapy Training Unit; GUTS - Fighting Bowel Cancer

Recruiting

FIT in Diverticulitis

Colorectal Cancer | Diverticulitis

United Kingdom
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer

Metastatic Pancreatic Adenocarcinoma | Stage IV Pancreatic Cancer AJCC v6 and v7 | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Gastroesophageal Junction Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Malignant... and other conditions

United States
Diwakar Davar
Aculeus Therapeutics

Active, not recruiting

Pixatimod (PG545) Plus Nivolumab in PD-1 Relapsed/Refractory Metastatic Melanoma and NSCLC and With Nivolumab and Low-dose Cyclophosphamide in MSS Metastatic Colorectal Carcinoma (mCRC)

NSCLC | Metastatic Colorectal Carcinoma | Refractory Melanoma

United States
Imperial College London

Completed

Optical Polyp Testing for In Vivo Classification (OPTIC)

Colonic Diseases | Colonic Polyp | Colonic Neoplasms | Colonic Cancer | Colonic Adenocarcinoma | Colonic Adenoma | Colonic Carcinoma | Colonic Dysplasia | Colon Hyperplastic Polyp

United Kingdom
University College London Hospitals
University Hospital Southampton NHS Foundation Trust

Completed

Cardiopulmonary Exercise Testing and Preoperative Risk Stratification

Critical Illness | Anaesthesia | Colorectal Cancer

United Kingdom
University of Leicester

Completed

Combining Curcumin With FOLFOX Chemotherapy in Patients With Inoperable Colorectal Cancer (CUFOX)

Metastasis | Colonic Cancer

United Kingdom
Queen Mary University of London
Royal Free Hospital NHS Foundation Trust

Active, not recruiting

Investigation of a Transcatheter Tricuspid Valved Stent Graft in Patients With Carcinoid Heart Disease (TRICAR)

Carcinoid Syndrome | Carcinoid Heart Disease | Tricuspid Regurgitation | Tricuspid Valve Disease

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Neoadjuvant Epirubicin, Cisplatin and Capecitabine (ECX) Followed by Definitive Chemoradiation With/Without Surgery for Squamous Cell Carcinoma of the Oesophagus

Oesophageal Carcinoma

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Circulating Cell-Free Tumor DNA Testing in Guiding Treatment for Patients With Advanced or Metastatic Colorectal Cancer

Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC v8 | Stage IIIC Colorectal Cancer AJCC... and other conditions

United States

Clinical Trials on Colorectal Carcinoma in United Kingdom

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