Clinical Trials on Common Variable Immune Deficiency

Total 5533 results

Bellicum Pharmaceuticals

Terminated

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

Hemoglobinopathies | Hemophagocytic Lymphohistiocytosis | Metabolic Disorders | Primary Immune Deficiency Disorders | Inherited Bone Marrow Failure Syndrome

United States
Universidad de Valparaiso

Recruiting

Effect of Treatment for Vitamin D Deficiency on Thyroid Function and Autoimmunity in Hashimoto's Thyroiditis.

Vitamin D Deficiency | Hashimoto Disease | Treatment Levothyroxine

Chile
National Institute of Allergy and Infectious Diseases...

Completed

Vitamin A to Reduce HIV in Vaginal Secretions and Prevent Viral Transmission

HIV Infections | Vitamin A Deficiency | HIV Seronegativity
Sandoz

Completed

A Multicenter Placebo-Controlled Dose Titration Study to Evaluate the Efficacy and Safety of Sandostatin (SMS 201-995) in the Treatment of Patients With Acquired Immunodeficiency Related Diarrhea

HIV Infections | Diarrhea

United States
Sandoz

Completed

A Multicenter Placebo-Controlled Double Blind Study to Evaluate the Efficacy and Safety of Sandostatin ( SMS 201-995 ) in Patients With Acquired Immunodeficiency Related Diarrhea Who Were Either "Responders" or "Non-Responders" in a Prior Placebo-Controlled Double-Blind Sandostatin Study.

HIV Infections | Diarrhea

United States
Johns Hopkins University

Completed

Treatment of Vitamin D Deficiency in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis | Vitamin D Deficiency

United States
University Hospital, Clermont-Ferrand
CRINEX Laboratory; BP 337 - 3 rue de Gentilly; 92541 MONTROUGE Cedex FRANCE

Unknown

Study of the Efficacy and Safety of Cholecalciferol Supplementation on the Activity of Rheumatoid Arthritis in Patients With Vitamin D Deficiency (SCORPION)

Rheumatoid Arthritis | Vitamin D Deficiency

France
Peking Union Medical College Hospital

Recruiting

Neoadjuvant Immunotherapy for T4 dMMR Colon Cancer (NITDC)

Colon Cancer | Immunotherapy | Mismatch Repair Deficiency

China
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Lentiviral Gene Therapy for p47 AR-CGD

P47-Phox, Deficiency of

United Kingdom
University of Sao Paulo

Completed

Lymphocyte Count as a Sign of Immunoparalysis and Its Correlation With Nutritional Status in Septic Pediatric Patients

Lymphopenia
National Cancer Institute (NCI)

Recruiting

Allogeneic Hematopoietic Stem Cell Transplantation With JSP191-Based Conditioning in Participants With GATA2 Deficiency

Immunodeficiency | GATA2

United States
Nationwide Children's Hospital
Ohio State University

Unknown

Vitamin D in Pediatric Asthma: a Randomized Controlled Open-label Pilot Trial (D-Asthma)

Vitamin D Deficiency | Asthma

United States
Hamad Medical Corporation

Completed

Rapid vs Maintenance Vitamin D Supplementation in Deficient Children With Asthma to Prevent Exacerbations.

Vitamin D Deficiency | Asthma

Qatar
Federico II University

Completed

Calcium and Vitamin D Intakes in Children

Hypocalcemia | Hypovitaminosis D
Nottingham University Hospitals NHS Trust
CICbioGUNE; Christian-Albrechts-University of Kiel; University of Veterinary...

Not yet recruiting

Genetic Carbohydrate Maldigestion as a Model to Study Food Hypersensitivity (GenMalCarb)

Irritable Bowel Syndrome (IBS) | Sucrase Isomaltase Deficiency
PATH
Bill and Melinda Gates Foundation; Centre National de Greffe de Moelle Osseuse and other collaborators

Not yet recruiting

Evaluation of an IgG Deficiency Rapid Screening Test: A Performance Study With Primary Immunodeficiency (PID) Patients in Tunisia

Primary Immunodeficiency Diseases

Tunisia
Children's Hospital of Philadelphia
University of California, San Francisco

Recruiting

Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies

Immunodeficiencies | Immune Dysregulation Syndromes

United States
Gary M Brittenham, MD

Active, not recruiting

Daily Vitamin D for Sickle-cell Respiratory Complications (ViDAS-2)

Respiratory Tract Infections | Respiratory Tract Diseases | Respiration Disorders | Lung Diseases | Nutrition Disorders | Vitamin D Deficiency | Asthma | Sickle Cell Disease | Anemia, Sickle Cell | Anemia, Hemolytic, Congenital | Acute Chest Syndrome | Deficiency Diseases Vitamin

United States
Lallemand Pharma AG

Completed

Symbiofilm Trial in Allergic Kids (SYMBIOFILM-TAK)

Allergy | Common Cold

Poland
National Cheng-Kung University Hospital
Tainan Hospital, Ministry of Health and Welfare

Enrolling by invitation

Pyloric or Pseudopyloric Metaplasia of the Corpus Mucosa in Autoimmune Gastritis (PM_in_AIG)

Autoimmune Diseases | Metaplasia | Gastritis, Atrophic | Helicobacter Pylori Gastritis | Anemia, Pernicious

Taiwan
Al-Azhar University

Completed

Vitamin D Supplementation and Glycemic Control Improvement Among Type 1 Diabetic Children

Vitamin D Deficiency | Type 1 Diabetes Mellitus

Palestinian Territory, occupied
National Cancer Institute (NCI)

Recruiting

Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency

DOCK8 Deficiency

United States
MurciaSalud

Completed

Efficacy of Calcifediol Supplementation in Asthma Control in Asthmatic Patients With Vitamin D Deficiency (ACViD) (ACViD)

Asthma, Bronchial

Spain
Lawson Health Research Institute

Completed

Micronutrient Supplemented Probiotic Yogurt for HIV/AIDS and Other Immunodeficiencies

HIV Infections | Cancer, Second Primary

Canada
Pharvaris Netherlands B.V.

Recruiting

Study of Oral Deucrictibant Soft Capsule for On-Demand Treatment of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema (RAPIDe-3)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States, Puerto Rico
Pharvaris Netherlands B.V.

Recruiting

Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema (RAPIDe-2)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States, Bulgaria, Czechia, Hungary, Spain, France, Germany, Poland, Canada, Israel
Brigham and Women's Hospital

Completed

Personalized Immunotherapeutic for Antibiotic-resistant Infection

Infection | Immune Deficiency | Hypogammaglobulinemia | Septic Arthritis | Mycoplasma Hominis

United States
St. Justine's Hospital
Toronto-Dominion Bank of Canada Funds for Clinical Research projects.

Completed

Pilot Study of a New Device (Buzzy®) for Procedural Pain Relief During Needle-Related Procedures in Paediatric Patients

Immune Deficiency | Autoimmune Rheumatologic Disease | Pain Due to Certain Specified Procedures | Child/Adolescent Problems

Canada
Joanne Kurtzberg, MD
Duke University; Miltenyi Biotec, Inc.

Available

Expanded Access to T-cell Depleted Haplo-Identical Stem Cells for Patients Receiving Haplo-Identical and Unrelated Cord Blood Transplants

Hematologic Malignancies | Immune Deficiencies | Inborn Errors of Metabolism Disorders

United States
University Hospitals Cleveland Medical Center
Case Western Reserve University

Recruiting

Zinc Effect on Inflammation and Cardiovascular Risk in HIV

Cardiovascular Diseases | Inflammation | Zinc Deficiency

United States
William Beaumont Hospitals

Completed

Prevalence of Vitamin D Deficiency in Type 1 Diabetes Mellitus and Effect of Supplementation on Insulin Requirements

Type 1 Diabetes Mellitus

United States
The Netherlands Cancer Institute
Bristol-Myers Squibb

Recruiting

Neoadjuvant Immune Checkpoint Inhibition and Novel IO Combinations in Early-stage Colon Cancer (NICHE)

Colon Carcinoma

Netherlands
Edward Kim
National Cancer Institute (NCI)

Completed

Oxaliplatin Microdosing Assay in Predicting Exposure and Sensitivity to Oxaliplatin-Based Chemotherapy

Colon Adenocarcinoma

United States
King's College London
University of Sheffield; University of Manchester; National Health Service, United... and other collaborators

Recruiting

The Experience of Screening for SCID

Severe Combined Immunodeficiency

United Kingdom
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Genetic Basis of Immunodeficiency

Severe Combined Immunodeficiency

United States
David Williams
University of California, Los Angeles; Boston Children's Hospital; Children's...

Completed

Gene Transfer for Severe Combined Immunodeficiency, X-linked (SCID-X1) Using a Self-inactivating (SIN) Gammaretroviral Vector

Severe Combined Immunodeficiency

United States
St. Jude Children's Research Hospital

Completed

Transplantation of Hematopoietic Cells in Children With Severe Combined Immunodeficiency Syndrome

Severe Combined Immunodeficiency

United States
Jasper Therapeutics, Inc.

Recruiting

JSP191 Antibody Targeting Conditioning in SCID Patients

SCID

United States
Taiga Biotechnologies, Inc.

Not yet recruiting

Safety and Early Efficacy Study of TBX-1400 in Patients With Severe Combined Immunodeficiency

Severe Combined Immunodeficiency

Israel
Donald B. Kohn, M.D.
National Institutes of Health (NIH); FDA Office of Orphan Products Development

Completed

MND-ADA Transduction of CD34+ Cells From Children With ADA-SCID

Severe Combined Immunodeficiency

United States
Johns Hopkins University

Completed

Safety and Immunologic Effect of Low Dose Versus High Dose Vitamin D3 in Multiple Sclerosis

Multiple Sclerosis | Vitamin D Deficiency

United States
University Hospital, Montpellier

Terminated

The Role of the Coagulation Pathways in Recurrent Angioedema (Angiocoag)

Chronic Spotaneous Urticaria, Idiopathic Non Histaminergic Angioderma, Hereditary Angioedema With C1 Inhibitor Deficiency

France
University of Liverpool

Recruiting

An Exploratory Study of Arginine Supplementation and the Postoperative Immune REsponse (ASPIRE)

Surgery | Preterm | Nutritional Deficiency | Immune System and Related Disorders

United Kingdom
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by a Donor Stem Cell Transplant in Treating Patients With Immunodeficiency or Other Nonmalignant Inherited Disorders

Immunodeficiency Syndrome | Non-Cancer Diagnosis

United States
Octapharma

Terminated

Efficacy, Safety and Kinetics Study of Octagam 10% in Primary Immunodeficiency Diseases

Immunologic Deficiency Syndromes

Austria
Khalifa University for Science and Technology
Sheikh Khalifa Medical City; Zayed Military Hospital; Cleveland Clinic Abu Dhabi and other collaborators

Unknown

Impact of Burnout on Cardiovascular and Immune Biomarkers in Healthcare Professionals - Covid-19 Pandemic in Abu Dhabi

Burnout | Cardiovascular Risk Factor | Immune Deficiency

United Arab Emirates
Istanbul University

Unknown

Correlation Between Partial Oxygen Pressure and Oxygen Reserve Index

COLON CANCER

Turkey
University of California, San Francisco

Recruiting

Autologous Gene Therapy for Artemis-Deficient SCID

Severe Combined Immunodeficiency

United States
St. Jude Children's Research Hospital

Active, not recruiting

Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)

Severe Combined Immunodeficiency

United States
Association Pour l'Aide a la Recherche en Immunologie...

Completed

Study Through Imaging of Visceral Lymphoid Organs in Patients With SCID Who Have Recieved Bone Marrow Allograft (LymphImaging)

Severe Combined Immunodeficiency

France

Clinical Trials on Common Variable Immune Deficiency

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Burkina Faso

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