Clinical Trials on Community Based Study

Total 1796 results

University of Copenhagen
Nordsjaellands Hospital

Completed

Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5 (REMA-CKD)

Kidney Diseases | Renal Insufficiency | CKD | Metabolic Acidosis | Pre-dialysis

Denmark
University Hospital Inselspital, Berne

Completed

Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tubular Acidosis

Nephrolithiasis | Acidosis, Renal Tubular | Vacuolar Proton-Translocating ATPases

Switzerland
Erasmus Medical Center

Enrolling by invitation

Explorative Study to Investigate the Acid-base Response to Sodium and Potassium Salts in Patients With Chronic Kidney Disease. (5S)

CKD | Electrolyte and Fluid Balance Conditions | Metabolic Acidosis

Netherlands
AstraZeneca

Terminated

Study of the Effect of SZC on Serum Potassium and Serum Bicarbonate in Patients With Hyperkalemia and Metabolic Acidosis Associated With Chronic Kidney Disease (NEUTRALIZE)

Chronic Kidney Disease | Metabolic Acidosis | Hyperkalaemia

United States, Puerto Rico
Biotest

Recruiting

Efficacy and Safety of Trimodulin (BT588) in Subjects With CAP Including COVID-19 Pneumonia (TRICOVID)

COVID-19 | Pneumonia | Acute Respiratory Distress Syndrome | Community-acquired Pneumonia | Respiratory Infection | Bacterial Pneumonia | Viral Pneumonia | Fungal Pneumonia

Belgium, Brazil, Latvia, Germany, Lithuania, South Africa, Argentina, Austria, France, Hungary, Slovakia, Turkey, Portugal, Spain
Advicenne Pharma

Terminated

Study Evaluating Subjects With Distal Renal Tubular Acidosis

Distal Renal Tubular Acidosis

United States, Canada
Advicenne Pharma

Withdrawn

Extension Study in Primary Distal Renal Tubular Acidosis

Acidosis, Renal Tubular

United States
University Hospital, Geneva
ModernaTX, Inc.; University of Geneva, Switzerland

Active, not recruiting

Mucosal Immunity: Influence on Infectious Viral Load: a Prospective Observational Study (MIViral)

SARS-CoV-2 Infection | RSV Infection | Influenza Viral Infections | Virus Shedding | Mucosal Immunity

Switzerland
DLR German Aerospace Center
University of Aarhus; University of Trieste; European Space Agency

Completed

The Effect of Potassium Bicarbonate on Bone and Several Physiological Systems During Immobilisation (NUC)

Sprains and Strains | Body Weight Changes | Muscular Atrophy | Bone Diseases, Metabolic | Cardiovascular Abnormalities | Acid-Base Imbalance | Protein Metabolism

Germany
DLR German Aerospace Center
University Hospital, Angers; University of Zurich; University Hospital, Bonn; European... and other collaborators

Completed

Short Term Bed Rest Study: Evaluation of the Use of Artificial Gravity, Induced by Short-arm Centrifugation (SAG)

Sprains and Strains | Body Weight Changes | Muscular Atrophy | Bone Diseases, Metabolic | Cardiovascular Abnormalities | Acid-Base Imbalance | Protein Metabolism

Germany
Vapotherm, Inc.
University of Maryland; George Washington University; The Cooper Health System; Valley Presbyterian Hospital and other collaborators

Active, not recruiting

Clinical Stabilization of Hypercapnia: NIPPV v HVNI (HYPERACT)

Chronic Obstructive Pulmonary Disease | Dyspnea | Hypercapnic Respiratory Failure | Hypercapnic Acidosis

United States
Uppsala University

Completed

Evaluation of Respiratory Function in Fibromyalgia

Fibromyalgia | Respiratory Alkalosis and Metabolic Acidosis | Chronic Hyperventilation

Sweden
Hoffmann-La Roche

Completed

A Study Of Mircera In Patients With Kidney Disease Who Are Not On Dialysis

Renal Tubular Acidosis, Distal, With Hemolytic Anemia

Serbia
University of Southern California
National Institute on Aging (NIA); Huntington Hospital

Completed

Social Work Intervention Focused on Transitions (SWIFT)

Depression | Stroke | Hypertension | Diabetes | Cancer | Chronic Obstructive Pulmonary Disease | Asthma | Chronic Heart Failure | Heart Disease | Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention

United States
Humanitas Hospital, Italy

Recruiting

Metformin in Diabetic Patients Undergoing Coronary Angiography (NO-STOP)

Coronary Artery Disease | Diabetes Mellitus | Contrast-induced Nephropathy | Lactic Acidosis With Diabetes Mellitus | Metformin Associated Lactic Acidosis

Italy
University of Colorado, Denver

Completed

Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD

Cognitive Dysfunction | Chronic Kidney Disease | Metabolic Acidosis

United States
University Hospitals Cleveland Medical Center

Terminated

Efficacy, Safety Study and Benefit of Alkali Therapy in Sickle Cell Disease

Chronic Kidney Disease | Sickle Cell Anemia | Metabolic Acidosis

United States
University Hospital, Montpellier
Fisher and Paykel Healthcare

Not yet recruiting

Nasal High Flow Versus Non-invasive Ventilation for Early Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Hypercapnic Acidosis (HiCOPD)

Acute Exacerbation of Chronic Obstructive Pulmonary Disease | Hypercapnic Acidosis | Respiratory Failure With Hypercapnia

France
Marmara University
Bulent Ecevit University; Mustafa Kemal University; TC Erciyes University; Kahramanmaras... and other collaborators

Unknown

Postoperative Complications in Patients With Obesity Hypoventilation Syndrome (OHBE)

Obstructive Sleep Apnea | Acid-Base Imbalance | Hypercapnia | Obesity Hypoventilation Syndrome | Post-Op Complication

Turkey
Vanderbilt University Medical Center
American Cancer Society, Inc.

Completed

New Modalities for Detection of Oropharyngeal Cancer

Oropharynx Cancer | Tonsil Cancer | Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma | Base of Tongue Carcinoma

United States
Klinikum Wels-Grieskirchen
Genzyme, a Sanofi Company

Completed

Anderson-Fabry Disease in Chronic Kidney Disease Patients Not on Renal Replacement Therapy

Focus of Study: Prevalence of Fabry Disease in CKD Population

Austria
St. Paul's Sinus Centre

Not yet recruiting

Utility of Indocyanine Green Fluorescence in Endoscopic Sinonasal and Skull Base Surgery (NIRFICG)

Chronic Sinusitis | Skull Base Neoplasms | Tumor of Nasal Sinus | Posterior Epistaxis
Children's Hospital of Philadelphia
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Withdrawn

Increasing Ureagenesis in Inborn Errors of Metabolism With N-Carbamylglutamate

Urea Cycle Disorders, Inborn | Inborn Errors of Metabolism | Propionic Acidemia | Methylmalonic Acidemia | Carbamyl Phosphate Synthetase Deficiency
National Cancer Institute (NCI)

Recruiting

Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors

Locally Advanced Chondrosarcoma | Metastatic Chondrosarcoma | Metastatic Sinonasal Adenocarcinoma | Locally Advanced Sinonasal Adenocarcinoma | Metastatic Large-cell Neuroendocrine Carcinoma | Locally Advanced Large-cell Neuroendocrine Carcinoma | Metastatic Olfactory Neuroblastoma | Locally Advanced... and other conditions

United States
Michio Hirano
Santhera Pharmaceuticals

Completed

Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like Episodes (MELAS)

MELAS Syndrome

United States
University of California, Davis
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Vanderbilt...

Recruiting

Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD (Senergy-CKD)

Diabetes | Fatigue | Chronic Kidney Diseases | Insulin Resistance | Metabolic Acidosis | Physical Endurance | Mitochondrial Energetics

United States
University Hospital, Ghent

Completed

Clinical Study to Determine the Optimal Operation Parameters During CO2 Removal With the Abylcap® System

ARDS (Acute Respiratory Distress Syndrome) | Respiratory Acidosis

Belgium
University Hospital, Ghent

Completed

Veno-venous Extracorporeal CO2 Removal in ARDS-patients to Treat Respiratory Acidosis

ACUTE RESPIRATORY DISTRESS SYNDROME

Belgium
Glasgow Royal Infirmary

Completed

Alcohol: Thiamine and or Magnesium 1 (AToM1)

Magnesium Deficiency | Alcohol Withdrawal | Lactic Acidosis | Vitamin B1 Deficiency | Wernicke Encephalopathy

United Kingdom
National Center for Research Resources (NCRR)
University of California, San Diego

Completed

Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic Acidemia

MELAS Syndrome | Lactic Acidosis | Mitochondrial Myopathy

United States
Hospital Son Llatzer

Completed

Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation. (TRAMA)

Pulmonary Disease, Chronic Obstructive | Obesity Hypoventilation Syndrome | Metabolic Alkalosis

Spain
Jesús González de la Aleja Tejera

Completed

Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome

MELAS Syndrome

Spain
National Institute of Diabetes and Digestive and...

Completed

Evaluating Patients With Abnormal Levels of Gastric Acid

Gastrinoma | Zollinger Ellison Syndrome | Achlorhydria

United States
Tisento Therapeutics
Children's Hospital of Philadelphia

Terminated

Phase 2a Study of IW-6463 in Adults Diagnosed With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS)

MELAS

United States
Tisento Therapeutics

Not yet recruiting

A Phase 2b Study of Zagociguat in Patients With MELAS (PRIZM)

Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)

United States, Australia, Italy, Germany, Canada, United Kingdom
Benha University

Completed

Impact Of Maternal Spinal Anesthesia-Induced Hypotension At Scheduled Cesarean Delivery On Risk Development Of Transient Tachypnea Of Newborn And Fetal Acidosis

Transient Tachypnea of Newborn and Fetal Acidosis

Egypt
Mendel Tuchman
Children's Hospital of Philadelphia; University of California, Los Angeles; Icahn... and other collaborators

Completed

Short-Term Outcome of N-Carbamylglutamate in the Treatment of Acute Hyperammonemia (STO)

Methylmalonic Acidemia | Carbamoyl-Phosphate Synthase I Deficiency Disease | Propionic Acidemia, Type I and/or Type II | Ornithine Carbamoyltransferase Deficiency

United States
University Hospital, Rouen

Unknown

Efficacy of Volume Ventilation in Patients With Acute Respiratory Failure at Risk of Obstructive Apneas or Obesity Hypoventilation (VONIVOO)

Obesity | Acute Respiratory Failure | Hypercapnic Respiratory Failure | Apnea, Obstructive | Hypoventilation Syndrome | Respiratory Acidosis
Washington University School of Medicine

Completed

Auditory Nerve Test System During Vestibular Schwannoma Resection (ANTS)

Sensorineural Hearing Loss | Skull Base Neoplasms | Vestibular Schwannoma | Acoustic Neuroma | Asymmetric Sensorineural Hearing Loss | Cochlear Nerve Damage | Cochlear Nerve Deafness | Auditory; Nerve

United States
Rigshospitalet, Denmark
University College, London

Enrolling by invitation

EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV (EuroSIDA)

End Stage Liver Disease | Cardiovascular Diseases | Fractures, Bone | Diabetes Mellitus | Renal Insufficiency | Hepatitis B | Hepatitis C | Kidney Failure, Chronic | Proteinuria | HIV | Coinfection | Acidosis, Lactic | AIDS

Spain, Switzerland, Germany, United Kingdom, Austria, Sweden, Finland, Israel, Denmark, France, Italy, Iceland, Belgium, Slovakia, Norway, Lithuania, Portugal, Poland, Croatia, Czechia, Greece, Hungary, Luxembourg, Argentina, Belarus, Bosnia... and more
Min-Sheng General Hospital

Completed

Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient

Liver Diseases | Heart Failure | Stroke | Pneumonia | Septic Shock | Respiratory Failure | Trauma | Acute Kidney Injury | Diabetic Ketoacidosis | Head Injury | GastroIntestinal Bleeding | Intracerebral Hemorrhage | Heart Disease, Ischemic

Taiwan
Region Skane

Not yet recruiting

Checklists Resuscitation Emergency Department

Pneumonia | Burns | Shock | Poisoning | Abdominal Pain | Chest Pain | Trauma | Fever | Bradycardia | Syncope | Seizures | Vertigo | Tachycardia | Cardiac Arrest | Diabetic Ketoacidosis | Shortness of Breath | Allergic Reaction | Asthma Acute | Altered Mental Status | COPD Exacerbation Acute | Pulmonary Edema - Acute | Hyperglycemic Hyperosmolar...
Khondrion BV
Julius Clinical; ProPharma Group; Certara

Completed

The KHENEREXT Study

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) | Chronic Progressive External Ophthalmoplegia (CPEO)

Netherlands, Denmark, United Kingdom, Germany
West Kazakhstan Medical University

Recruiting

Selective Screening of Children for Hereditary Metabolic Diseases by Tandem Mass Spectrometry in Kazakhstan

Ornithine Transcarbamylase Deficiency | Biotinidase Deficiency | Citrullinemia | Glutaric Acidemia Type II | Argininosuccinic Aciduria | Maple Syrup Urine Disease | Primary Carnitine Deficiency | Homocystinuria | Carnitine Palmitoyltransferase II Deficiency | Arginase Deficiency | Very Long-chain Acyl-CoA... and other conditions

Kazakhstan
UK Kidney Association

Recruiting

National Registry of Rare Kidney Diseases (RaDaR)

Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy | Atypical Hemolytic Uremic Syndrome | Autosomal Dominant Polycystic Kidney Disease | Cystinosis | Nephronophthisis | BK Nephropathy and other conditions

United Kingdom
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium

Clinical Trials on Community Based Study

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Medical Conditions

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CROs by country

CROs in Zimbabwe

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Rare Diseases

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