Clinical Trials on Complex Anal Fistulas in United Kingdom

Total 1402 results

London North West Healthcare NHS Trust

Completed

The Impact of 3D Anal Fistula Models on Patient Understanding and Decision Making (3DAF)

Fistula in Ano | Ano Fistula

United Kingdom
London North West Healthcare NHS Trust
St Mark's Hospital Foundation

Unknown

Nutritional Management of Acute and Chronic Enterocutaneous Fistulae

Enterocutaneous Fistulae

United Kingdom
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer (InterAACT)

Anal Squamous Cell Carcinoma | Anal Basaloid Carcinoma | Anal Canal Cloacogenic Carcinoma | Metastatic Anal Canal Carcinoma | Recurrent Anal Canal Carcinoma | Stage IIIB Anal Canal Cancer | Stage IV Anal Canal Cancer

United States
Medtronic - MITG

Completed

A Prospective, Multi-center, Observational Study of the Use of Permacol™ Collagen Paste to Treat Anorectal Fistulas

Anorectal Fistulas

Denmark, United Kingdom, Italy
Tigenix S.A.U.

Completed

Efficacy and Safety of Adipose Stem Cells to Treat Complex Perianal Fistulas Not Associated to Crohn´s Disease (FATT1)

Anal Fistula

Spain, Germany, United Kingdom
The University of Texas Health Science Center,...
CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCES

Recruiting

BIOlogic Augmented Repair of Complex Anal Fistula Using Acellular Matrix and/or Autologous Platelet-rich Plasma (BIO RAMP)

Anal Fistula

United States
Denver Health and Hospital Authority
3M

Withdrawn

The Role of VAC Therapy Devices in Promoting Closure of Enterocutaneous Fistulae (ECF)

Fistulae

United States
Weill Medical College of Cornell University
Angiocrine Bioscience

Recruiting

E-CEL UVEC as an Adjunct Cell Therapy for Treatment of Anal Fistulas

Anal Fistula

United States
RedDress Ltd.

Recruiting

A Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02 For the Management of Anal Fistulas

Anal Fistula

United States, Israel
University of Southern California

Completed

Treatment of Perirectal Fistula With Cutting Seton vs. Collagen Plug

Anal Fistula

United States
Rush University Medical Center

Terminated

A Prospective Evaluation of the Strattice-LIFT to Treat Anal Fistula

Rectal Fistula | Anal Fistula | Fistula in Ano | Transsphincteric Fistula

United States
Cook Group Incorporated

Completed

Ligation of the Intersphincteric Fistula Tract (LIFT) + Biodesign for Anal Fistula (LIFT+Graft)

Anal Fistula

United States
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer

Anal Canal Squamous Cell Carcinoma | Metastatic Anal Canal Carcinoma | Stage IV Anal Canal Cancer AJCC v6 and v7

United States, Canada
Colon and Rectal Surgery Associates, Ltd.
Massachusetts General Hospital; University of Pennsylvania; University of Ottawa

Unknown

Ligation of Intersphincteric Fistula Tract (LIFT) Procedure Versus Use of an Anal Fistula Plug for Anal Fistula Repair (LIFT vs PLUG)

Anal Fistula

United States, Canada
Cook Group Incorporated

Completed

Retrospective Review of the Cook Biodesign® Fistula Plug to Treat Anorectal Fistulas

Anorectal Fistula

United States, Germany
Daniel Dante Yeh
Takeda

Completed

Teduglutide for Enterocutaneous Fistula (ECF)

Postoperative Fistula

United States
Wake Forest University Health Sciences

Completed

Stereotactic Radiation to Decrease Pancreatic Secretions

Pancreatic Fistulae

United States
Cook Group Incorporated
Cook Biotech Incorporated

Terminated

Treatment of Crohn's Fistula Using a Porcine Intestine Submucosa Graft (SurgiSIS AFP)

Crohn's Disease | Anal Fistula

United States
Takeda

Active, not recruiting

A Study of Surgical Interventions in Fistulizing Conditions

Fistula | Crohns Disease | Rectovaginal Fistula | Complex Perianal Fistula | Complex Cryptoglandular Fistula

United States, Netherlands, Belgium, Israel, Italy, United Kingdom, Czechia, Austria, Canada, France
NHS Greater Glasgow and Clyde

Unknown

Qutenza (Topical Capsaicin 8%) for Painful Arteriovenous Fistulae

Neuropathic Pain | Arteriovenous Fistulae

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Trial Comparing the Incidence of Steal Syndrome in the Two Types of anTEcubitaL Fossa Arteriovenous fistuLa AVF (STEAL)

Steal Syndrome | Arteriovenous Fistulas | Renal Failure, End-Stage

United Kingdom
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

Anal Basaloid Carcinoma | Anal Canal Cloacogenic Carcinoma | Anal Canal Squamous Cell Carcinoma | Anal Margin Squamous Cell Carcinoma | Stage I Anal Cancer AJCC v8 | Stage IIA Anal Cancer AJCC v8

United States
Microvention-Terumo, Inc.
ClinSearch

Completed

PHIL Evaluation in the Endovascular Treatment of Intracranial Dural AVF

Dural Arteriovenous Fistula

United Kingdom, Spain, Denmark, France, Sweden
University College, London
University College London Hospitals

Recruiting

TIPS Microspheres for Perianal Fistula

Perianal Fistula

United Kingdom
University of Vermont
American Society of Colon and Rectal Surgeons

Completed

Pre-Emptive Analgesia in Ano-Rectal Surgery (PEAARS)

Rectal Fistula | Hemorrhoids | Fissure in Ano | Anal Condyloma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal Lesions

High Grade Anal Canal Intraepithelial Neoplasia | High Grade Vulvar Squamous Intraepithelial Lesion

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility Trial

Stage III Anal Cancer AJCC v8 | Anal Canal Squamous Cell Carcinoma | Stage IIB Anal Cancer AJCC v8 | Stage IIIA Anal Cancer AJCC v8 | Stage IIIB Anal Cancer AJCC v8 | Stage IIIC Anal Cancer AJCC v8 | Stage I Anal Cancer AJCC v8 | Stage II Anal Cancer AJCC v8 | Stage IIA Anal Cancer AJCC v8

United States
Ohio State University
Spiration, Inc.

Withdrawn

Spiration IBV® Valve System and Spiration Airway Sizing Kit

Management of BPF (Bronchopleural Fistulae)

United States
Takeda

Completed

Long-term Follow-up Study With Darvadstrocel in the Treatment of Complex Perianal Fistula

Crohn's Disease | Complex Perianal Fistula

United States, Spain, France, Belgium, Israel, Czechia, Italy, Poland, Hungary
Great Ormond Street Hospital for Children NHS Foundation...
National Institute for Health Research, United Kingdom

Recruiting

Swallowing, Feeding and Eating in Children Born With Oesophageal Atresia/Trache-oesophageal Fistula (OA/TOF) (SaFE)

Esophageal Atresia With Tracheoesophageal Fistula

United Kingdom
University of Edinburgh
Helsinki University Central Hospital

Recruiting

Distal Pancreatectomy Pancreatic Fistula Risk Prediction Model Validation Study (DPFValid)

Pancreatic Fistula | Pancreatectomy

United Kingdom
Birmingham Women's and Children's NHS Foundation...

Not yet recruiting

Use of Indocyanine Green During Primary Repair of Oesophageal Atresia and Distal Tracheo-oesophageal Fistula (iTOF)

Tracheo-Esophageal Fistula With Atresia of Esophagus

United Kingdom
London North West Healthcare NHS Trust

Recruiting

CArE for OAsI Study: Care Pathways and Anorectal Evaluation for OASI Associated Incontinence (CArE for OAsI)

Anal Incontinence | Faecal Incontinence | Follow-up | Biofeedback | Obstetric Anal Sphincter Injury | Urogynaecology | Urgency | Severe Perineal Trauma | Grade 3 Perineal Tear | Grade 4 Perineal Tear | Deferral Time | Pathways | Review | Endo-anal Ultrasound

United Kingdom
London North West Healthcare NHS Trust

Terminated

Efficacy of an Anorectal Fistula Plug With Sealing of the Internal Opening as a Treatment for Perianal Fistula

Fistula in Ano

United Kingdom
Cardiff University

Recruiting

Phase 1b/II Trial of Pembrolizumab Plus IMRT in Stage III/IV Carcinoma of Anus (CORINTH)

Anal Cancer Stage III A | Anal Cancer Stage III B

United Kingdom, Norway
Lewisham and Greenwich NHS Trust

Completed

Diagnosis of Obstetric Anal Sphincter Injuries (OASIs) Using Transperineal Ultrasound Scan (TPUS)

Obstetric Anal Sphincter Injury

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood Gases (CO2)

Congenital Diaphragmatic Hernia | Esophageal Atresia With Tracheo-esophageal Fistula

United Kingdom
Massachusetts General Hospital
National Cancer Institute (NCI)

Unknown

Concurrent Chemoradiation + 5-FU + Mitomycin-C in Anal Carcinoma

Carcinoma of the Anal Canal

United States
London North West Healthcare NHS Trust

Completed

Primary Repair of Obstetric Anal Sphincter Injuries (OASIS) by Surgeons (PROS Study) (PROS)

Obstetric Anal Sphincter Injury

United Kingdom
Incyte Corporation

Completed

A Study of INCMGA00012 in Squamous Carcinoma of the Anal Canal Following Platinum-Based Chemotherapy (POD1UM-202)

Squamous Cell Carcinoma of Anal Canal

Spain, United Kingdom, United States, Germany, Belgium, France, Denmark, Italy, Norway
University Hospital Birmingham
Boston Scientific Corporation

Unknown

Drug Eluting Balloon Venoplasty in AV Fistula Stenosis (DeVA)

Stenosis | Native Arteriovenous Fistula

United Kingdom
Mayo Clinic

Enrolling by invitation

Virtual Reality in Electrophysiology Laboratory (EP)

Ablation | PVC - Premature Ventricular Complex

United States
Laser Surgery Care
QIAGEN Gaithersburg, Inc

Completed

Hybrid Capture 2 Human Papiloma Virus (HPV) High-Risk Anal DNA Test

Anal Cancer | Anal Canal HPV Infection Diagnosis | Anal Dysplasia Diagnosis

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC; AIDS and Cancer Specimen Resource

Active, not recruiting

Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection

HIV Infection | Anal Squamous Cell Carcinoma | Stage 0 Anal Canal Cancer | Stage I Anal Canal Cancer

United States
National Cancer Institute (NCI)

Recruiting

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

Anal Canal Cloacogenic Carcinoma | Metastatic Anal Squamous Cell Carcinoma | Recurrent Anal Squamous Cell Carcinoma | Stage III Anal Cancer AJCC v8 | Stage IV Anal Cancer AJCC v8 | Unresectable Anal Squamous Cell Carcinoma | Anal Basaloid Squamous Cell Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

HIV Infection | Anal Squamous Cell Carcinoma | Anal Canal Cloacogenic Carcinoma | Stage III Anal Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Anal Margin Squamous Cell Carcinoma | AIDS-Related Anal Carcinoma | Rectal Squamous Cell Carcinoma | Stage I Anal Cancer AJCC... and other conditions

United States
Ascopharm Groupe Novasco

Completed

Open, Multicentric Trial Evaluating the Efficacy and the Clinical Tolerance of PA0903 as Root Canal Sealer (PA0903)

Root Canal Obturation

France, United Kingdom
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer

Anal Canal Cloacogenic Carcinoma | Stage III Anal Cancer AJCC v8 | Anal Margin Squamous Cell Carcinoma | Stage IIB Anal Cancer AJCC v8 | Anal Basaloid Squamous Cell Carcinoma

United States, Canada
Belfast Health and Social Care Trust

Recruiting

The Northern Ireland Haemodialysis Vascular Access Database (NIVAD)

Hemodialysis Access Failure | Arteriovenous Fistula

United Kingdom
Hull University Teaching Hospitals NHS Trust
University of Hull

Completed

Vein Histology in Arteriovenous Fistulas and Its Effect on Fistula Surgery Success

Renal Replacement Therapy | Arteriovenous Fistula

United Kingdom

Clinical Trials on Complex Anal Fistulas in United Kingdom

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