Clinical Trials on Complex Atypical Endometrial Hyperplasia

Total 238 results

National Institutes of Health Clinical Center (CC)

Completed

X-Ray Mammography Standard of Care Protocol

Breast Cancer | Invasive Carcinoma | Atypical Ductal Hyperplasia | In Situ Carcinoma | Fibrocystic Changes

United States
National Cancer Institute (NCI)

Completed

Thalidomide in Treating Patients With Recurrent or Persistent Endometrial Cancer

Recurrent Endometrial Carcinoma | Endometrial Adenocarcinoma | Endometrial Clear Cell Carcinoma | Endometrial Papillary Serous Carcinoma | Endometrial Adenosquamous Cell Carcinoma | Endometrial Adenoacanthoma

United States
National Cancer Institute (NCI)
NRG Oncology

Completed

Selumetinib in Treating Patients With Recurrent or Persistent Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Adenocarcinoma | Endometrial Adenosquamous Carcinoma

United States
Centre Leon Berard

Recruiting

Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS) (BFR-ESS)

Low Grade Endometrial Stromal Sarcoma

France
St. Jude Children's Research Hospital
Millennium Pharmaceuticals, Inc.; Takeda Pharmaceuticals U.S.A., Inc.

Active, not recruiting

Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors (SJATRT)

Malignant Rhabdoid Tumor | Atypical Teratoid Rhabdoid Tumor

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia

High Grade Squamous Intraepithelial Neoplasia | Stage 0 Uterine Corpus Cancer

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Gemcitabine in Treating Patients With Recurrent or Persistent Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Adenocarcinoma | Endometrial Adenosquamous Carcinoma

United States
Hasanuddin University
Chulalongkorn University

Recruiting

Predictors of Ovarian Cancer and Endometrial Cancer for Artificial-Intelligence-Based Screening Tools

Ovarian Cancer | Endometrial Hyperplasia | Endometrial Cancer

Indonesia
National Cancer Institute (NCI)
NRG Oncology

Completed

Cediranib Maleate in Treating Patients With Recurrent or Persistent Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Adenocarcinoma | Endometrial Adenosquamous Carcinoma

United States
Dana-Farber Cancer Institute

Recruiting

Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

Obesity | Endometrial Carcinoma | Endometrial Cancer Stage I | Endometrial Intraepithelial Neoplasia | EIN

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Intraperitoneal Paclitaxel, Doxorubicin Hydrochloride, and Cisplatin in Treating Patients With Stage III-IV Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Endometrial Adenosquamous Carcinoma | Endometrial Mixed Adenocarcinoma | Stage IIIA Uterine Corpus Cancer | Stage IIIC Uterine Corpus Cancer | Stage... and other conditions

United States
Memorial Sloan Kettering Cancer Center

Completed

A Study of Durvalumab With or Without Tremelimumab in Endometrial Cancer

Endometrial Cancer | Endometrial Carcinoma | Endometrial Carcinosarcoma | Endometrial Cancer Recurrent | Endometrial Carcinoma, Recurrent

United States
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb

Completed

A Study of Nivolumab in Selected Uterine Cancer Patients

Carcinosarcoma | Leiomyosarcoma | Endometrial Carcinoma | Uterine Cancer | Clear Cell Carcinoma | Undifferentiated Sarcoma | High Grade Endometrial Stromal Sarcoma

United States
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb

Active, not recruiting

Study of BMS-986205 and Nivolumab in Endometrial Cancer or Endometrial Carcinosarcoma That Has Not Responded to Treatment

Endometrial Adenocarcinoma | Endometrial Carcinosarcoma

United States
Lei Li

Recruiting

Prognosis of Low-grade Endometrial Stromal Sarcoma

Recurrence | Survival Outcomes | Adjuvant Therapy | Hormone Therapy | Low Grade Endometrial Stromal Sarcoma of Uterus (Diagnosis) | Fertility-sparing Surgery | Fertility Outcomes

China
National Cancer Institute (NCI)

Completed

Akt Inhibitor MK2206 in Treating Patients With Recurrent or Advanced Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Adenocarcinoma | Endometrial Adenosquamous Carcinoma

United States
Mayo Clinic

Recruiting

Non-Invasive Identification of Endometrial Cancer/Endometrial Atypical Hyperplasia With an AI-Based Classifier Applied to Transvaginal Ultrasound in Patients With Post-Menopausal Bleeding

Endometrial Carcinoma

United States
WellSpan Health

Active, not recruiting

Frequency of Endometrial Cancer Precursors Associated With Lynch Syndrome

Endometrial Hyperplasia | Lynch Syndrome | Endometrial Cancer | Microsatellite Instability | Mismatch Repair Deficiency

United States
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Phase I/II Thymus Transplantation With Immunosuppression #950 (#950)

DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome | Complete Atypical DiGeorge Anomaly | Complete Atypical DiGeorge Syndrome

United States
Andrea DeCensi
European Institute of Oncology; Associazione Italiana per la Ricerca sul Cancro

Active, not recruiting

Trial of Low Dose Tamoxifen in Women With Breast Intraepithelial Neoplasia - Long Term Follow-up (TAM-01)

Breast Neoplasms | Carcinoma, Intraductal, Noninfiltrating | Recurrence, Local Neoplasm | Atypical Hyperplasia

Italy
Hung-Hsueh Chou
Bristol-Myers Squibb; GlaxoSmithKline

Unknown

A Phase I Study of Lapatinib (Tykerb) Plus Ixabepilone (Ixempra) as 2nd-line Treatment for Patients With HER-2 Overexpressed Recurrent or Persistent Endometrial Carcinoma or Carcinosarcoma

Recurrent Endometrial Cancer
Novartis Pharmaceuticals

Completed

Medical Safety Follow-up Study for Patients Who Received More Than 28 Days of Total Exposure to BGG492

Adrenocortical Adenoma | Endometrial Stromal Sarcomas

Germany, United States, Korea, Republic of, Hungary, Italy, Slovakia
Gynecologic Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

Comparison of Two Combination Chemotherapy Regimens Plus Radiation Therapy in Treating Patients With Stage III or Stage IV Endometrial Cancer

Stage III Uterine Corpus Cancer | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Adenocarcinoma | Endometrial Adenosquamous Carcinoma | Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation

United States
Children's Mercy Hospital Kansas City
University of Kansas Medical Center

Recruiting

Naltrexone Neuroimaging in Teens With Eating Disorders (NN-RCT)

Bulimia Nervosa | Binge Eating | Purging (Eating Disorders) | Eating Disorders | Anorexia Nervosa, Atypical

United States
Memorial Sloan Kettering Cancer Center
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Pembrolizumab and Olaparib in People With Endometrial Cancer or Endometrial Carcinosarcoma

Endometrial Carcinosarcoma

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

VSV-hIFNbeta-NIS With or Without Ruxolitinib Phosphate in Treating Stage IV or Recurrent Endometrial Cancer

Recurrent Endometrial Adenocarcinoma | Recurrent Endometrial Carcinoma | Recurrent Endometrial Clear Cell Adenocarcinoma | Recurrent Endometrial Endometrioid Adenocarcinoma | Recurrent Endometrial Mixed Cell Adenocarcinoma | Recurrent Endometrial Serous Adenocarcinoma | Recurrent Endometrial Undifferentiated... and other conditions

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Trebananib in Treating Patients With Persistent or Recurrent Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Adenocarcinoma | Endometrial Adenosquamous Carcinoma | Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation | Endometrioid Stromal Sarcoma

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Making Informed Choices on Incorporating Chemoprevention Into Care (MiCHOICE)

Atypical Hyperplasia of the Breast | Lobular Breast Carcinoma In Situ | Pleomorphic Lobular Breast Carcinoma In Situ

United States, Guam
University of Texas Southwestern Medical Center

Recruiting

Targeting Social Function to Improve Outcomes in Eating Disorders (SF-ED)

Anorexia Nervosa | Bulimia Nervosa | Purging (Eating Disorders) | Eating Disorders | Atypical Anorexia Nervosa | Other Specified Feeding or Eating Disorder

United States
Gloucestershire Hospitals NHS Foundation Trust

Suspended

Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval Disease (Vulval VS)

Lichen Sclerosus | Squamous Cell Carcinoma | Normal Vulval Skin | High Grade Dysplasia - Usual Type ('VIN 2-3') | High Grade Dysplasia - Differentiated Type ('VIN 2-3') | Epithelial Hyperplasia Without Atypia | Atypia Not Otherwise Specified/ Low Grade Dysplasia ('VIN 1') | Pagets Disease of the...

United Kingdom
M.D. Anderson Cancer Center

Recruiting

Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in High-Risk Endometrial Cancers

Endometrial Clear Cell Adenocarcinoma | Endometrial Dedifferentiated Carcinoma | Endometrial Serous Adenocarcinoma | Malignant Uterine Neoplasm | Endometrial Mucinous Adenocarcinoma | Uterine Corpus Carcinosarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Withdrawn

Biomarker Study in Samples From Patients With Malignant Rhabdoid Tumor of the Kidney or Atypical Teratoid Rhabdoid Tumor

Childhood Atypical Teratoid/Rhabdoid Tumor | Rhabdoid Tumor of the Kidney

United States
Frederic Amant
Kom Op Tegen Kanker; Research Foundation Flanders

Completed

FUlvestrant in Gynecological Cancers That Are Potentially Hormone Sensitive: the FUCHSia Study (FUCHSia)

Endometrial Cancer | Endometrial Stromal Sarcoma | Sex Cord Stromal Tumor | Adenosarcoma of Uterus | Leiomyosarcoma Uterus | Serous Ovarian Tumor

Belgium, Netherlands
Memorial Sloan Kettering Cancer Center
Zymeworks BC Inc.

Completed

ZW25 in Women With Endometrial Cancers

Carcinosarcoma | Endometrial Cancer

United States
Medical University of Graz

Terminated

Vorinostat (SAHA) in Uterine Sarcoma

Leiomyosarcoma | Endometrial Stromal Tumors | Carcinosarcomas Uterine

Austria
University of Louisville
King's College London; National Institute of Mental Health (NIMH)

Recruiting

Online Relapse Prevention Study (ORP)

Anorexia Nervosa | Bulimia Nervosa | Eating Disorders | Anorexia Nervosa, Atypical | Other Specified Feeding or Eating Disorder

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Medroxyprogesterone in Treating Patients With Endometrioid Adenocarcinoma of the Uterine Corpus

Recurrent Uterine Corpus Carcinoma | Stage I Uterine Corpus Cancer | Stage II Uterine Corpus Cancer | Stage III Uterine Corpus Cancer | Stage IV Uterine Corpus Cancer | Endometrial Adenocarcinoma | Endometrial Adenosquamous Carcinoma | Endometrial Endometrioid Adenocarcinoma, Variant With Squamous...

United States
Assaf-Harofeh Medical Center

Unknown

A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma

Soft Tissue Sarcoma | Osteosarcoma | Chondrosarcoma | Bone Sarcoma | Desmoplastic Small Round Cell Tumor | Gastrointestinal Stromal Sarcoma | Ewing's Tumor Metastatic | Ewing's Tumor Recurrent
Drexel University
National Institute of Mental Health (NIMH)

Active, not recruiting

Optimizing Mindfulness and Acceptance Based Behavioral Treatment for Bulimia Nervosa and Binge Eating Disorder

Binge-Eating Disorder | Bulimia Nervosa | Binge Eating | Bulimia; Atypical | Binge-Eating and Purging Type Anorexia Nervosa

United States
National Cancer Institute (NCI)
Radiation Therapy Oncology Group

Completed

Intensity-Modulated Radiation Therapy, Cisplatin, and Bevacizumab Followed by Carboplatin and Paclitaxel in Treating Patients Who Have Undergone Surgery for Endometrial Cancer

Stage IA Uterine Corpus Cancer AJCC v7 | Stage IB Uterine Corpus Cancer AJCC v7 | Stage II Uterine Corpus Cancer AJCC v7 | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Adenocarcinoma | Stage IIIA Uterine Corpus Cancer AJCC v7 | Stage IIIB Uterine Corpus... and other conditions

United States, Canada, Hong Kong
National Cancer Institute (NCI)

Not yet recruiting

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

Breast Carcinoma | Breast Ductal Carcinoma In Situ | Breast Lobular Carcinoma In Situ | Breast Atypical Hyperplasia

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Caloric Restriction Before Surgery in Treating Patients With Endometrial, Prostate, or Breast Cancer

Breast Carcinoma | Endometrial Carcinoma | Prostate Carcinosarcoma

United States
Alkü Alanya Education and Research Hospital

Unknown

TWO DİFFERENT ELECTROSURGERY DEVICES AS MONOPOLAR HOOC AND PLASMAKINETIC BIPOLAR SPATULA EFFECTIVENESS DURING COLPOTOMY

Endometrial Hyperplasia | Uterine Fibroid | Cervical Dysplasia | Ovary Cyst

Turkey
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing the Addition of Trastuzumab or Trastuzumab/Pertuzumab to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Endometrial Serous Adenocarcinoma | Uterine Corpus Carcinosarcoma

United States, Puerto Rico
National Cancer Institute (NCI)

Not yet recruiting

Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction

Breast Carcinoma | Breast Ductal Carcinoma In Situ | Breast Lobular Carcinoma In Situ | Breast Atypical Hyperplasia

United States
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Adenocarcinoma | Recurrent Uterine Corpus Cancer | Stage IIIA Uterine Corpus Cancer AJCC v7 | Stage IIIB Uterine Corpus Cancer AJCC v7 | Stage IIIC Uterine Corpus Cancer AJCC v7 | Stage IVA Uterine Corpus Cancer... and other conditions

United States
Floor Backes

Terminated

Tislelizumab for the Treatment of Recurrent Mismatch Repair Deficient Endometrial Cancer

Lynch Syndrome | Recurrent Endometrial Carcinoma | Recurrent Endometrial Clear Cell Adenocarcinoma | Recurrent Endometrial Cancer | Metastatic Endometrial Cancer | Mismatch Repair Deficiency | Recurrent Uterine Corpus Carcinosarcoma

United States
University of Alabama at Birmingham

Recruiting

Cabozantinib and Dostarlimab in Recurrent Gynecologic Carcinosarcoma

Carcinoma | Gynecologic Cancer | Endometrial Cancer | Uterine Cancer

United States
Australian & New Zealand Children's Haematology...
National Health and Medical Research Council, Australia; Secura Bio, Inc.

Terminated

A Study of Panobinostat in Pediatric Patients With Solid Tumors Including MRT/ATRT (NORTH)

Rhabdoid Tumor | Atypical Teratoid/Rhabdoid Tumor | Malignant Rhabdoid Tumor | Recurrent Brain Tumor, Childhood

Australia, New Zealand, United States
University of Manchester
Cardiff University; AstraZeneca

Active, not recruiting

Does Cediranib With Paclitaxel, or Cediranib and Olaparib, Treat Advanced Endometrial Cancer Better Than Paclitaxel? (COPELIA)

Endometrial Neoplasms | Carcinosarcoma

United Kingdom

Clinical Trials on Complex Atypical Endometrial Hyperplasia

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