Clinical Trials on Congenital Disorders

Total 149651 results

University of Sao Paulo General Hospital

Recruiting

iSGLT2 in Prevention of Acute Kidney Injury in Patients With Diabetes Mellitus Undergoing CABG Extracorporeal On-Pump (POST-CABGDM)

Coronary Artery Disease | Diabetes Mellitus, Type 2 | Acute Kidney Injury | Coronary Artery Bypass Surgery

Brazil
Nanjing Medical University

Recruiting

Outcome of Patients Treated With ECLS

Heart Failure | Cardiac Arrest | Acute Respiratory Distress Syndrome | Cardiogenic Shock | Acute Respiratory Failure

China
University of Cologne

Recruiting

Hantavirus Registry - HantaReg (HantaReg)

Hantavirus Infections | Hemorrhagic Fever With Renal Syndrome | Nephropathia Epidemica | Hantavirus Cardiopulmonary Syndrome

Germany
Omar Aljitawi

Recruiting

Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Chronic Myelomonocytic Leukemia | Myelodysplastic/Myeloproliferative Neoplasm | Atypical Chronic Myeloid Leukemia | Chronic Monocytic Leukemia

United States
Ischemia Care LLC

Recruiting

Biomarkers of Acute Stroke in Clinic (BASIC)

Ischemia | Stroke | Ischemic Stroke | Atherosclerosis | Atrial Fibrillation | Transient Ischemic Attack | Cardiomyopathies | Thromboembolism | Stroke, Ischemic | Stroke, Acute | Thrombotic Stroke | Stroke, Complication | Cardioembolic Stroke | Cardiovascular Stroke | Atheroma | Stroke of Basilar Artery | Transient Cerebrovascular...

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Not yet recruiting

Cost of Cancer Risk Management in Women at Elevated Genetic Risk for Ovarian Cancer Who Participated on GOG-0199

Fallopian Tube Carcinoma | Ovarian Carcinoma | Hereditary Breast and Ovarian Cancer Syndrome | Primary Peritoneal Carcinoma

United States
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

Endometrial Endometrioid Adenocarcinoma | Stage I Uterine Corpus Cancer AJCC v8 | Stage II Uterine Corpus Cancer AJCC v8

United States, Puerto Rico
Centre Hospitalier Henri Duffaut - Avignon

Terminated

Interleukine 6 (IL6) Assay for Predicting Failure of Spontaneous Breathing in Patients With COVID-19 Acute Respiratory Distress Syndrome

COVID-19 Acute Respiratory Distress Syndrome

France
Moscow City Oncology Hospital No. 62

Completed

[SENTRY] Tailoring Postoperative Management Through Sentinel Lymph Node Biopsy in Low- and Intermediate-Risk Endometrial Cancer (SENTRY)

Endometrial Neoplasms | Endometrial Cancer | Sentinel Lymph Node | Endometrial Endometrioid Adenocarcinoma | Endometrial Adenocarcinoma | Hysterectomy | Endometrial Cancer Stage I | Laparoscopic Hysterectomy | Endometrial Cancer Stage II

Russian Federation
University of Minnesota
United States Department of Defense

Completed

The Role of Cytomegalovirus and Inflammation on Patient Symptoms and Outcomes in Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma

United States
North Eastern German Society of Gynaecological...
Clovis Oncology, Inc.; Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus...

Active, not recruiting

Rucaparib MAintenance After Bevacizumab Maintenance Following Carboplatin Based First Line Chemotherapy in Ovarian Cancer Patients (MAMOC)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer | Clear Cell Carcinoma

Germany
Oncoinvent AS

Active, not recruiting

Study of Radspherin® in Recurrent Ovarian Cancer Subjects With Peritoneal Carcinomatosis

Ovarian Cancer | Peritoneal Carcinomatosis

Belgium, Spain, Norway
Bayer

Completed

Study on the Safety of BAY1817080 How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given to Participants With Moderate Renal Impairment and End Stage Renal Disease Requiring Dialysis Compared With Matched Participants With Normal Renal Function

Overactive Bladder | Diabetic Neuropathic Pain | Endometriosis Related Pain | Refractory or Unexplained Chronic Cough

United States
Fred Hutchinson Cancer Center
University of California, San Diego; National Heart, Lung, and Blood Institute... and other collaborators

Active, not recruiting

Women's Health Initiative Strong and Healthy Study (WHISH)

Myocardial Infarction | Stroke | Mortality | Sleep | Depressive Symptoms | Hip Fractures | Peripheral Artery Disease | Falls | Physical Function | Cardiovascular Mortality | Coronary Revascularization | Venous Thromboembolic Event | Mobility and Independence | Clinical (Non-hip) Fractures
Icahn School of Medicine at Mount Sinai

Active, not recruiting

VNS for Long-COVID-19

Postural Tachycardia Syndrome | Post-COVID-19 Syndrome | Dysautonomia

United States
GlaxoSmithKline

Completed

Impact of Boostrix™ Maternal Vaccination on Morbidity and Mortality of Pertussis Disease in Infants ≤6 Weeks of Age, in Bogota, Colombia.

Tetanus | Diphtheria | Acellular Pertussis | Diphtheria-Tetanus-acellular Pertussis Vaccines | Aspergillosis, Allergic Bronchopulmonary

Colombia
Eurasian Association of Therapists

Completed

Clinical Register Studying the therApeutic Patient Population With Multifocal Atherosclerosis (KAMMA)

Cardiovascular Diseases | Chronic Kidney Diseases | Atherosclerosis | Bleeding | Acute Coronary Syndrome | Cardiac Death | Acute Stroke | Polyvascular Disease | Atherosclerosis Generalized

Russian Federation
Centre Hospitalier Universitaire de Nice

Completed

Prone Positioning and R/I Ratio in COVID-19 Patients With ARDS (SyDRAC-DV) (SyDRAC-DV)

COVID-19 Acute Respiratory Distress Syndrome

France
University Medical Centre Ljubljana
University of Ljubljana, Faculty of Medicine, Institute of Pharmacology and...

Completed

Role of the ATP7A Transporter in Ovarian Cancer (ATHOC)

Gynecologic Cancer | Ovarian Cancer | Chemotherapy Effect | High Grade Serous Carcinoma

Slovenia
Mainline Biosciences, Inc.

Withdrawn

A Phase 1 Study to Evaluate Paclitaxel Conjugated CXC Receptor 4 Antagonist (MB1707) in Patients With Advanced Cancer

Breast Cancer | Pancreatic Neoplasms | Non Small Cell Lung Cancer | Advanced Solid Tumor | Ovary Cancer
ARCAGY/ GINECO GROUP
AstraZeneca

Completed

Genomic BRCA and Extensive ovArian Cancer Testing (GREAT)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Peritoneal Cancer

France
St. Justine's Hospital
CHU de Quebec-Universite Laval; Montreal Children's Hospital of the MUHC

Active, not recruiting

Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.

Low-grade Glioma | Plexiform Neurofibroma | Central Nervous System Glioma

Canada
Ankara City Hospital Bilkent
Baskent University

Completed

Early Versus Delayed Enteral Nutrition in Critically Ill Adults With COVID-19

Enteral Nutrition | COVID-19 Acute Respiratory Distress Syndrome

Turkey
Hoffmann-La Roche

Completed

A Study Evaluating the Safety, Pharmacokinetics and Efficacy of Ipatasertib Administered in Combination With Rucaparib in Participants With Advanced Breast, Ovarian Cancer, and Prostate Cancer.

Breast Cancer | Ovarian Cancer | Prostate Cancer

United States, Korea, Republic of, Italy, Australia, Spain
Sanguine Biosciences
Novo Nordisk A/S

Completed

Biorepository of Biospecimen Samples in Matched Healthy Control Participants and Participants Diagnosed With Diabetic Kidney Disease, Chronic Kidney Disease, or Type 2 Diabetes (SAN-08961)

Healthy | Chronic Kidney Diseases | Diabetic Kidney Disease | Diabetes Type 2

United States
Assistance Publique - Hôpitaux de Paris

Completed

Characterization of the Postural Habits of Wheelchair Users Analysis of the Acceptability of International Recommendations in the Prevention of Pressure Sores Risk by Using a Connected Textile Sensor (Es-Alert)

Duchenne Muscular Dystrophy | Spinal Muscular Atrophy

France
M.D. Anderson Cancer Center

Completed

Clearance Of Mucus In Stents (COMIS)

Myocardial Infarction | Pneumonia | Lung Neoplasms | Respiratory Failure | Unstable Angina | Cardiac Arrhythmia | Acute Coronary Syndromes | Thromboembolic Disease

United States
Aveni Foundation

Withdrawn

CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19 (CORONA)

COVID-19 | Acute Respiratory Distress Syndrome | Cytokine Storm
Lynkcell Europe

Enrolling by invitation

Phase I Clinical Trials Investigating the Potential Efficacy of Axitinib in Patients With a BRCA 1/2 Mutations

Breast Cancer | Breast Neoplasms | Ovarian Neoplasms | Ovarian Cancer | HER2-positive Breast Cancer | HER2-negative Breast Cancer | HER-2 Protein Overexpression | BRCA Mutation

Ukraine
Seoul National University Hospital

Completed

Survival Impact of Internal Mammary or Supraclavicular Lymphadenectomy (SDLNOC)

Lymph Node Metastases | Ovarian Cancer Stage IV

Korea, Republic of
Karolinska Institutet
Karolinska University Hospital

Enrolling by invitation

Effects of Individual Tailored Physical Exercise in Patients With POTS After COVID-19 - a Randomized Controlled Study

COVID-19 | Postural Orthostatic Tachycardia Syndrome | Post COVID-19 Condition | Post-Acute COVID-19 Syndrome

Sweden
University of Washington
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Stage IV HLA-A2 and HER2 Positive Breast or Ovarian Cancer Receiving Trastuzumab

Stage IV Breast Cancer | HER2/Neu Positive | HLA-A2 Positive Cells Present | Stage IV Ovarian Cancer

United States
University of California, San Francisco
Sanofi; Genentech, Inc.

Terminated

Combination Chemotherapy and Bevacizumab in Treating Patients With Advanced Neuroendocrine Tumors

Lung Cancer | Neuroendocrine Tumor | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome

United States
The University of Texas Health Science Center,...
United States Department of Defense; Akebia Therapeutics Inc.

Completed

Vadadustat for the Prevention and Treatment of Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19)

Coronavirus Infection | Acute Respiratory Distress Syndrome

United States
Banc de Sang i Teixits

Completed

Efficacy and Safety Evaluation of Mesenchymal Stem Cells for the Treatment of Patients With Respiratory Distress Due to COVID-19 (COVIDMES)

COVID-19 | SARS-CoV 2 | Adult Respiratory Distress Syndrome

Spain
Barretos Cancer Hospital

Completed

Neoadjuvant Carboplatin in Triple Negative Breast Cancer

BRCA1 Hereditary Breast and Ovarian Cancer Syndrome

Brazil
Turkish Society of Pediatric Gastroenterology,...

Completed

Study Determining the Frequency of Duchenne Muscular Dystrophy and Late-onset Pompe Disease (VICTORIA)

Duchenne Muscular Dystrophy | Pompe Disease (Late-onset)

Turkey
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, Los Angeles; University... and other collaborators

Completed

Evaluating Quality of Life in Patients With AIDS-Associated Kaposi Sarcoma Treated With Bleomycin and Vincristine

Human Immunodeficiency Virus 1 Positive | AIDS-Related Kaposi Sarcoma

Tanzania
Central Hospital, Nancy, France

Completed

Comparison of ARDS COVID-19 (WHO) vs ARDS Influenza in the ICU

Influenza | ARDS | COVID-19 Acute Respiratory Distress Syndrome

France
University of Minnesota
Bill and Melinda Gates Foundation

Completed

Losartan for Patients With COVID-19 Requiring Hospitalization

Acute Respiratory Distress Syndrome | Corona Virus Infection | SARS-CoV Infection

United States
Alexion Pharmaceuticals

Terminated

Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe Pneumonia

Pneumonia, Viral | Acute Respiratory Distress Syndrome | Acute Lung Injury | COVID-19 Severe Pneumonia

United States, Spain, United Kingdom, France, Japan
Sanofi Pasteur, a Sanofi Company

Completed

Regulatory Post-Marketing Surveillance Study for TETRAXIM™

Pertussis | Tetanus | Diphtheria | Poliomyelitis

Korea, Republic of
University Hospital, Antwerp

Completed

Flow-controlled Ventilation (FCV) in Moderate Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19 (VICAR)

Respiration, Artificial | COVID-19 Acute Respiratory Distress Syndrome

Belgium
William Beaumont Hospitals

Terminated

Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19 (SINK COVID-19)

Coronavirus Infections | COVID-19 | Acute Respiratory Distress Syndrome | Severe Acute Respiratory Syndrome (SARS)

United States
Denver Health and Hospital Authority
University of Colorado, Denver; University of Miami; Beth Israel Deaconess Medical... and other collaborators

Completed

Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection

Severe Acute Respiratory Syndrome | Respiratory Failure | Acute Respiratory Distress Syndrome

United States
Radboud University Medical Center

Terminated

Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVID-19) Infection Disease

Severe Acute Respiratory Syndrome | COVID-19 | COVID | Acute Respiratory Distress Syndrome | SARS-CoV-2

Netherlands
Gilead Sciences
United States Department of Defense

Completed

Phase Ib Study of SC Milatuzumab in SLE

Lupus Erythematosus, Systemic | Lupus Nephritis | Lupus Vasculitis, Central Nervous System | Lupus Erythematosus, Cutaneous | Lupus Erythematosus, Discoid

United States
Centre Leon Berard

Completed

Satisfaction and Quality of Life Comparison Between Patients Using Cicaplast Baume B5 Versus Dexeryl for the Management of Cutaneous Toxicities Induced by Epidermal Growth Factor Receptor Inhibitors (iEGFR) (CICAFIX)

Colorectal Cancer | Non Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Epidermal Growth Factor Receptor Inhibitor

France
Biocon Limited

Completed

Efficacy and Safety of Itolizumab in COVID-19 Complications

Covid19 | Acute Respiratory Distress Syndrome | Cytokine Release Syndrome

India
University of Milan

Completed

Ultrasound Grayscale Analysis in ARDS covid19 (Graycovid)

Muscular Diseases | COVID-19 Acute Respiratory Distress Syndrome

Italy

Clinical Trials on Congenital Disorders

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