Clinical Trials on Congenital Infection in Singapore

Total 426 results

Novartis
Novartis Pharmaceuticals

Completed

Switching Therapy From Lamivudine to Telbivudine Versus Continued Lamivudine in Adults With Chronic Hepatitis B

Chronic Hepatitis B

United States, United Kingdom, China, Taiwan, Canada, Singapore, New Zealand, Australia, France, Israel, Thailand
Medtronic Cardiac Rhythm and Heart Failure
The Cleveland Clinic

Completed

World-wide Randomized Antibiotic Envelope Infection Prevention Trial (WRAP-IT)

CIED Related Infection

Netherlands, United States, Italy, Switzerland, Finland, Spain, Chile, Greece, France, Israel, Poland, Singapore, Canada, Germany, Portugal, China, Sweden, United Kingdom, Belgium, Denmark, Saudi Arabia, Austria, Malaysia, Norway, Slovakia
Novartis Pharmaceuticals

Completed

A Dose Escalation/Expansion Study of LDK378 in Patients With Tumors Characterized by Genetic Abnormalities in Anaplastic Lymphoma Kinase

Tumors Characterized by Genetic Abnormalities of ALK

Australia, Belgium, Germany, Netherlands, Spain, Italy, Singapore, Korea, Republic of, United Kingdom, United States, Canada
KK Women's and Children's Hospital
National University Hospital, Singapore; Ramathibodi Hospital; Universiti Kebangsaan... and other collaborators

Completed

Pediatric Acute and Critical Care COVID-19 Registry of Asia (PACCOVRA)

COVID | Pediatric Disorder

Singapore, Pakistan, Malaysia, India, China, Indonesia, Japan
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemia (RADICHOL 1)

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Hyperlipoproteinemias | Lipid Metabolism, Inborn Errors | Hyperlipoproteinemia Type II | Metabolic... and other conditions

United States, Taiwan, Brazil, Canada, South Africa, United Kingdom, Singapore
Hoffmann-La Roche

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of RO7062931in Healthy Volunteers and Subjects With Chronic Hepatitis B

Chronic Hepatitis B

Australia, Hong Kong, Korea, Republic of, Taiwan, Thailand, New Zealand, Singapore
Gilead Sciences

Completed

Presatovir in Hematopoietic Cell Transplant Recipients With Respiratory Syncytial Virus Infection of the Upper Respiratory Tract

Respiratory Syncytial Virus

Korea, Republic of, Taiwan, Israel, United States, France, Singapore, Sweden, Australia, Canada, United Kingdom, Brazil, Germany, Netherlands, Spain, Switzerland
Gilead Sciences
Vir Biotechnology, Inc.

Active, not recruiting

Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB)

Chronic Hepatitis B

Hong Kong, Korea, Republic of, Denmark, Australia, Thailand, Singapore, United Kingdom, New Zealand
Janssen Research & Development, LLC

Completed

Efficacy and Safety of Combinations of AL-335, Odalasvir (ODV) and Simeprevir (SMV) in the Treatment of Chronic Hepatitis C Infection

Hepatitis C, Chronic

Poland, Belgium, Germany, Spain, Canada, Singapore
Sanofi Pasteur, a Sanofi Company

Completed

Study on a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Compared to a Meningococcal Reference Vaccine, and When Given Alone or With Two Other Vaccines in Healthy Adolescents

Healthy Volunteers | Meningococcal Immunisation

Spain, Hungary, Italy, Singapore
McMaster University
Canadian Institutes of Health Research (CIHR); Canadian Cancer Society (CCS); The Physicians' Services Incorporated Foundation and other collaborators

Completed

Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) (PARITY)

Bone Neoplasms | Infection

United States, Canada, Netherlands, Australia, Spain, Singapore, Brazil, India, Argentina, Austria, South Africa, Egypt
GlaxoSmithKline

Completed

Safety and Efficacy of H1N1 Vaccines in Children Aged 6 Months to Less Than 10 Years of Age

Influenza

Thailand, Australia, Mexico, Costa Rica, Philippines, Colombia, Singapore, Brazil
Bayer

Completed

Treatment of Patients With Acute Sinusitis

Acute Bacterial Sinusitis

China, France, Germany, Indonesia, Malaysia, Saudi Arabia, Singapore, Philippines, Austria, Jordan, Lebanon, Romania, Bahrain, Egypt, United Arab Emirates, Kuwait, Netherlands, Pakistan, Yemen
Pfizer

Completed

Skin Structure Infections With Suspected or Proven Methicillin-Resistant Staphylococcus Aureus (MRSA)

Skin/Soft Tissue Infections | Methicillin Resistant Staphylococcus Aureus (MRSA)

United States, Spain, United Kingdom, Colombia, Italy, Chile, Argentina, Mexico, Belgium, Russian Federation, Brazil, Malaysia, Singapore, Portugal, South Africa, Venezuela
Alios Biopharma Inc.

Completed

A Phase 2a Study to Evaluate Orally Administered ALS-008176 in Adults Hospitalized With a Respiratory Syncytial Virus

Respiratory Syncytial Virus Infections

Australia, Singapore, United States, New Zealand, Taiwan
CHIMES Society
National Medical Research Council (NMRC), Singapore

Completed

CHInese Medicine NeuroAid Efficacy on Stroke Recovery (CHIMES)

Stroke | Cerebral Infarction

Philippines, Thailand, Singapore, Hong Kong, Malaysia, Sri Lanka
Pfizer

Terminated

A Study To Evaluate The Safety Of Voriconazole As Treatment Of Invasive Aspergillosis (Fungal Infection) And Other Rare Molds In Children

Invasive Aspergillosis

Spain, United States, Singapore, Canada, Czechia, Netherlands, Poland, Thailand
Hoffmann-La Roche

Completed

A Retrospective Biomarker Study of Stored Samples Obtained From Patients With Chronic Hepatitis B

Hepatitis B, Chronic

Hong Kong, Taiwan, Singapore, Korea, Republic of, New Zealand, France, Thailand, Russian Federation, Australia, Italy
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
Cidara Therapeutics Inc.

Completed

Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis (ReSTORE)

Mycoses | Candidemia | Fungal Infection | Invasive Candidiases

United States, Israel, Spain, Korea, Republic of, Taiwan, Singapore, Thailand, Australia, China, Turkey, Belgium, Germany, France, Argentina, Bulgaria, Colombia, Greece, Italy
Abbott

Completed

Study of Lopinavir/Ritonavir Tablets Versus Soft Gel Capsules and Once Daily Versus Twice Daily Administration, When Coadministered With Nucleoside Reverse Transcriptase Inhibitors in Antiretroviral Naive Human Immunodeficiency Virus Type 1 Infected Subjects

Human Immunodeficiency Virus Infections

United States, Australia, Belgium, Canada, Czech Republic, France, Germany, Greece, Ireland, Italy, Netherlands, Poland, Puerto Rico, Russian Federation, Singapore, Spain, Switzerland, Taiwan, United Kingdom
Università Vita-Salute San Raffaele

Recruiting

Acute Normovolemic Hemodilution in High Risk Cardiac Surgery Patients. (ANH)

C.Surgical Procedure; Cardiac

Singapore, Saudi Arabia, Italy, Russian Federation, Serbia, Thailand
National Institute of Allergy and Infectious Diseases...
National Heart, Lung, and Blood Institute (NHLBI); University of Copenhagen; US... and other collaborators

Completed

Vaccination for Recovered Inpatients With COVID-19 (VATICO)

Covid19

United States, Spain, Uganda, Nigeria, Singapore, Switzerland
Brii Biosciences Limited
VBI Vaccines Inc.; Vir Biotechnology, Inc.

Completed

Study to Investigate the Safety and Efficacy of BRII-835 and BRII-179 Combination Therapy Treating Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B, Chronic

Australia, China, Korea, Republic of, New Zealand, Singapore, Thailand
Bayer

Completed

Liver MRI With Primovist/Eovist in Pediatric Subjects Who Are Suspected or Have Focal Liver Lesions.

Carcinoma | Liver Neoplasms | Adenoma | Liver Abscess

United States, Japan, Singapore, Taiwan, Italy
Hoffmann-La Roche

Completed

A Follow-Up Study to WV19432, to Evaluate Long Term Post-Treatment Effects of PEGASYS (Peginterferon Alfa-2a(40KD))in Patients With HBeAg Positive Chronic Hepatitis B

Hepatitis B, Chronic

China, Hong Kong, Taiwan, Singapore, Korea, Republic of, New Zealand, Thailand, Brazil, Russian Federation, Australia
Hoffmann-La Roche

Completed

A Screening Protocol to Assess Adults and Adolescents With Down Syndrome for Eligibility For Upcoming Study of RG1662 (Study BP27832)

Down Syndrome

United States, Spain, Canada, New Zealand, Argentina, Mexico, Singapore
Inovio Pharmaceuticals

Completed

Phase I Study of INO-1800 With or Without INO-9112 + EP in Chronic Hepatitis B Subjects

Hepatitis B

Australia, Taiwan, United States, Singapore, New Zealand, Hong Kong, Thailand, Philippines
Bayer

Completed

Greatest International Antiinfective Trial With Avelox (GIANT)

Bronchial Diseases | Bronchitis, Chronic

Switzerland, Poland, China, Croatia, Germany, Hungary, Indonesia, Korea, Republic of, Malaysia, Singapore, Philippines, Taiwan, Austria, Colombia, Hong Kong, Mexico, Slovenia, Turkey, Egypt, Morocco, Netherlands, Pakistan, Brazil, El...
The University of Queensland
University of Copenhagen; Erasmus Medical Center; Monash University; Hôpital Cochin and other collaborators

Recruiting

Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT)

Pulmonary Disease Due to Mycobacteria (Diagnosis)

Australia, Canada, Denmark, France, Ireland, Netherlands, New Zealand, United Kingdom, Singapore
Gilead Sciences

Completed

Study Comparing Tenofovir Disoproxil Fumarate (TDF), Emtricitabine (FTC)/TDF, and Entecavir (ETV) in the Treatment of Chronic HBV in Subjects With Decompensated Liver Disease.

Chronic Hepatitis B

United States, Canada, Spain, Singapore, Turkey, Germany, France, Taiwan, Greece, Italy, Poland
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE): Shionogi Protease Inhibitor (Ensitrelvir)

COVID-19

United States, Singapore, Japan, Ukraine, Georgia, Korea, Republic of, Australia, Denmark, Thailand, Greece, South Africa, Germany, Uganda, Spain, Puerto Rico, Argentina, Nigeria, United Kingdom, Brazil
Adamas Pharmaceuticals, Inc.

Completed

Oral Triple Combination Antiviral Drug Therapy for Treatment of Influenza A in Immunocompromised Subjects (PO206)

Influenza

United States, Australia, Canada, Netherlands, Singapore
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS) (SUNRISE)

Hidradenitis Suppurativa

Belgium, Italy, United Kingdom, United States, Hungary, Malaysia, Germany, Netherlands, France, Israel, Lebanon, Singapore, Spain, Bulgaria, Lithuania, Argentina, Turkey, Guatemala, Switzerland, Vietnam, Philippines, Croatia, India, S... and more
AbbVie

Recruiting

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy (Step-Up HS)

Hidradenitis Suppurativa

United States, Japan, Australia, Canada, Korea, Republic of, New Zealand, Puerto Rico, Spain, Austria, Italy, Bulgaria, Israel, Taiwan, Croatia, Hungary, Netherlands, Switzerland, Germany, Portugal, France, United Kingdom, Czechia, ... and more
Hoffmann-La Roche

Completed

A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)

Down Syndrome

United States, Italy, Argentina, France, Spain, Mexico, Canada, New Zealand, Singapore, United Kingdom
Novartis Pharmaceuticals

Completed

Telbivudine Versus Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis

Hepatitis | Hepatitis B, Chronic | Cirrhosis

United States, France, United Kingdom, Taiwan, Spain, Korea, Republic of, Singapore, New Zealand, Thailand, Germany, Israel, Russian Federation, Canada, China, Latvia, Turkey, Australia, India, Malaysia, Poland, Vietnam
Amryt Research Limited

Completed

Phase III Efficacy and Safety Study of Oleogel-S10 in Epidermolysis Bullosa (EASE)

Epidermolysis Bullosa

United States, Spain, Israel, Australia, France, Denmark, Switzerland, Italy, Hong Kong, Argentina, Austria, Brazil, Chile, Colombia, Czechia, Georgia, Germany, Greece, Hungary, Ireland, Romania, Russian Federation, Serbia, Singapore, U... and more
Gilead Sciences

Completed

A Study to Compare Tenofovir DF Versus the Combination of Emtricitabine Plus Tenofovir DF for the Treatment of Chronic Hepatitis B in Patients With Normal Alanine Aminotransferase (ALT)

Chronic Hepatitis B

Taiwan, France, Germany, Hong Kong, United States, Canada, New Zealand, Australia, Singapore, Poland, United Kingdom
Boehringer Ingelheim

Recruiting

Lunsayil 1: A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States, Korea, Republic of, Israel, Spain, Australia, Japan, Italy, Germany, Denmark, Belgium, Lithuania, China, Canada, Malaysia, Singapore, New Zealand, France, Mexico, Netherlands, Greece, United Kingdom, Bulgaria, Philipp... and more
Maasstad Hospital
Abbott Medical Devices

Completed

Comparison Between FFR Guided Revascularization Versus Conventional Strategy in Acute STEMI Patients With MVD. (CompareAcute)

Myocardial Infarction | Multivessel Coronary Artery Disease

Norway, Netherlands, Poland, Singapore, Germany, Czechia, Hungary, Sweden
Kirby Institute
Merck Sharp & Dohme LLC; amfAR, The Foundation for AIDS Research; Abbott

Completed

A Trial of 2 Options for Second Line Combination Antiretroviral Therapy Following Virological Failure of a Standard Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI)+2N(t)RTI First Line Regimen (SECOND-LINE)

HIV Infections

Taiwan, Australia, Argentina, Singapore, India, France, South Africa, Chile, Germany, Hong Kong, Ireland, Malaysia, Mexico, New Zealand, Nigeria, Peru, United Kingdom
Novartis Pharmaceuticals

Active, not recruiting

Extension Study to Assess Effects of Non-interrupted Versus Interrupted and Long Term Treatment of Two Dose Regimes of Secukinumab in Subjects With Hidradenitis Suppurativa

Hidradenitis Suppurativa

Belgium, Italy, United Kingdom, Hungary, Malaysia, Russian Federation, Taiwan, Germany, Netherlands, France, Israel, Korea, Republic of, Japan, Lebanon, United States, Australia, Singapore, Spain, Switzerland, Austria, Lithuania, ... and more
Hoffmann-La Roche

Completed

A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Hepatitis Be Antigen (HBeAg) Positive Chronic Hepatitis B (CHB).

Hepatitis B, Chronic

China, Hong Kong, Australia, Germany, Taiwan, Singapore, France, United States, Korea, Republic of, New Zealand, Thailand, Russian Federation, Brazil
Novartis Pharmaceuticals

Completed

16 Week Efficacy and 5 Year Long Term Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Ankylosing Spondylitis (MEASURE2)

Anklyosing Spondylitis

Germany, Austria, Spain, Switzerland, United Kingdom, United States, Singapore, Russian Federation, Netherlands, Italy, Finland, Czechia, Canada
National Institute of Allergy and Infectious Diseases...
Eli Lilly and Company; National Heart, Lung, and Blood Institute (NHLBI); University... and other collaborators

Completed

LY3819253 (LY-CoV555) for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)

COVID-19

United States, Denmark, Singapore, Spain
Abbott

Completed

Study of Lopinavir, Ritonavir, Tenofovir and Emtricitabine in HIV-Infected Antiretroviral Naïve Subjects

HIV Infections

Spain, United Kingdom, United States, France, Australia, Germany, Singapore
GlaxoSmithKline

Active, not recruiting

A Study on the Safety, Efficacy and Immune Response Following Sequential Treatment With an Anti-sense Oligonucleotide Against Chronic Hepatitis B (CHB) and Chronic Hepatitis B Targeted Immunotherapy (CHB-TI) in CHB Patients Receiving Nucleos(t)Ide Analogue (NA) Therapy

Hepatitis B, Chronic

Bulgaria, Belgium, Taiwan, Singapore, Spain, Germany, Thailand, Hong Kong, France, Italy, Poland, Philippines, Romania, United Kingdom, Turkey
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Hyperlipoproteinemias | Lipid Metabolism, Inborn Errors | Hyperlipoproteinemia Type II | Metabolic... and other conditions

United States, Canada, Brazil, Taiwan, Singapore, South Africa, United Kingdom
Bristol-Myers Squibb

Completed

Dose Ranging Study of Pegylated Interferon Lambda in Patients With Hepatitis B and Positive for the Hepatitis B e Antigen (LIRA-B)

Hepatitis B Virus

Australia, France, Germany, Korea, Republic of, Taiwan, United States, Canada, Italy, Netherlands, Singapore, Hong Kong

Clinical Trials on Congenital Infection in Singapore

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kenya

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations