Clinical Trials on Congenital Metabolic Disorder

Total 167629 results

National Cancer Institute (NCI)
Gynecologic Oncology Group

Completed

Vorinostat in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cavity Cancer

Primary Peritoneal Cavity Cancer | Recurrent Ovarian Epithelial Cancer

United States
Bursa Yüksek İhtisas Education and Research Hospital

Completed

Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease

Central Sensitisation | Behcet's Disease

Turkey
National Cancer Institute (NCI)

Withdrawn

Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)

Neoplasms, Nerve Tissue | Peripheral Nervous System Diseases | Heredodegenerative Disorders, Nervous System | Neurofibromatosis 1
University Health Network, Toronto

Terminated

Trial of Best Supportive Care and Either Cisplatin or Paclitaxel to Treat Patients With Primary Ovarian Cancer, Primary Peritoneal Cancer or Fallopian Tube Cancer and Inoperable Malignant Bowel Obstruction

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer | Bowel Obstruction

Canada
AstraZeneca

Completed

A Study to Evaluate Bioavailability and Food Effect of Selumetinib (AZD6244) in Healthy Male Participants

Healthy Participants | Neurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs)

United States
National Cancer Institute (NCI)

Completed

Cediranib Maleate in Treating Patients With Persistent, Recurrent, or Refractory Advanced Ovarian Epithelial, Peritoneal Cavity, or Fallopian Tube Cancer

Recurrent Ovarian Epithelial Cancer | Recurrent Primary Peritoneal Cavity Cancer | Recurrent Fallopian Tube Cancer

United States, Canada
Sidney Kimmel Cancer Center at Thomas Jefferson...
National Institutes of Health (NIH)

Terminated

Effect of Acetylcysteine With Topotecan Hydrochloride on the Tumor Microenvironment in Patients With Persistent or Recurrent High Grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Malignant Ovarian Endometrioid Tumor | Malignant Ovarian Serous Tumor

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Suspended

Atorvastatin in Preventing Nasopharyngeal Carcinoma Patients Receiving Radiotherapy From Carotid Stenosis

Nasopharyngeal Carcinoma | Radiation Therapy Complication

China
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure (Preemie iNO)

Pneumonia | Sepsis | Hypertension, Pulmonary | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn | Respiratory Distress Syndrome (RDS)

United States
Michigan State University
National Cancer Institute (NCI)

Completed

Improving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVR

Melanoma | Leukemia | Breast Neoplasms | Prostatic Neoplasms | Colorectal Neoplasms

United States
The Cleveland Clinic
GE Healthcare

Completed

Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis

Vasculitis | Giant Cell Arteritis | Arteritis | Takayasu's Arteritis | Aortitis

United States
University Hospital, Motol

Completed

Vertigo Perception and Quality of Life in Patients After Surgical Treatment of Vestibular Schwannoma (ITG)

Vestibular Schwannoma
Shenzhen SiBiono GeneTech Co.,Ltd

Unknown

p53 Gene in Treatment of Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer

Ovarian Epithelial Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

China
Universitaire Ziekenhuizen KU Leuven

Unknown

Ophthalmological Screening and Follow-up of Optic Pathway Gliomas in Children With Neurofibromatosis Type 1.

Neurofibromatosis Type 1

Belgium
Precision Therapeutics

Terminated

ChemoFx® PRO - A Post-Market Data Collection Study

Cervical Cancer | Uterine Neoplasms | Ovarian Cancer | Fallopian Tube Cancer | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer | Peritoneal Cancer

United States
Centre Francois Baclesse

Completed

Search Allelic Imbalance of Expression of BRCA Genes in Hereditary Risk of Breast and/or Ovarian Cancer (EXSAL)

Hereditary Breast and Ovarian Cancer Syndrome

France
Ain Shams University

Recruiting

Assessment Of Dose-Dependent Immunomodulatory Effect Of Alveofact With or Without Steroisd In Neonatal RDS

Inflammatory Response | Preterm Birth | Premature Lungs | Neonatal Respiratory Distress Syndrome | Neutrophil Extracellular Trap Formation

Egypt
Erasmus Medical Center
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma (RECMAP)

Glioblastoma | Brain Neoplasms | Recurrent Glioblastoma | Recurrent Adult Brain Tumor | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme of Brain | Brain Neoplasms, Adult, Malignant | Astrocytoma, Malignant | Brain Neoplasms, Adult

United States, Germany, Switzerland, Belgium, Netherlands
Sahar Mohammed Gad

Not yet recruiting

Chronic Kidney Disease Patient in Chronic Myloied Leukemia

Chronic Myeloid Leukemia in Remission
Jasper Gerritsen
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201) (SUPRAMAX)

Glioblastoma | Brain Neoplasms | Astrocytoma, Grade III | High-grade Glioma | Astrocytoma, Grade IV | Glioblastoma, IDH-mutant | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult | Brain Neoplasm, Primary | Brain Neoplasm, Malignant | Astrocytoma, Malignant | Brain Neoplasms, Adult

United States, Germany, Belgium, Switzerland, Netherlands
Maastricht University Medical Center

Recruiting

Complications and Recurrences After Mohs Micrographic Surgery and Slow Mohs

Recurrence | Complication of Surgical Procedure | Skin Cancer | Recurrent Disease | Complication | Complication,Postoperative | Lentigo Maligna Melanoma | Basal Cell Carcinoma | Cutaneous Squamous Cell Carcinoma | Lentigo Maligna

Netherlands
Medway NHS Foundation Trust

Recruiting

Umbilical Cord Abnormalities in the Prediction of Adverse Pregnancy Outcomes (ULOOP)

Hypoxic-Ischemic Encephalopathy | Admission to Neonatal Unit | Stillbirth | Small for Gestational Age at Delivery

United Kingdom
Therapeutic Advances in Childhood Leukemia Consortium

Recruiting

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

Neurofibromatosis 1 | JMML | Leukemia, Juvenile Myelomonocytic | JCML | CBL Syndrome

United States
AstraZeneca

Recruiting

Phase I/IIa Study for AZD5335 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Solid Tumors (FONTANA)

Ovarian Cancer | Lung Adenocarcinoma

United States, China, Spain, Canada, Australia, Taiwan, Israel, Japan, United Kingdom
Croatian Society for Organ Support
Clinical Hospital Centre Zagreb

Recruiting

European Registry for Hemadsorption in Sepsis With the Seraph Filter

Sepsis | Systemic Inflammatory Response Syndrome | Disease | Critical Illness | Acute Respiratory Distress Syndrome | Multi Organ Failure | Infections - Pathogen Unspecified

Croatia
Maastricht University Medical Center

Recruiting

Decisional Conflicts, Health-related QoL and Satisfaction With Care in High-risk cSCC in the Head-neck Region

Quality of Life | Satisfaction, Patient | Squamous Cell Carcinoma of the Head and Neck | Squamous Cell Carcinoma of Head and Neck | Skin Cancer | Squamous Cell Carcinomas | Squamous Cell Carcinoma of the Skin | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Cutaneous Squamous Cell Carcinoma | High-Risk Cancer

Netherlands
Nova Scotia Health Authority
Dalhousie University

Recruiting

Prehabilitation for Ovarian Cancer Patients

Ovarian Cancer | Frailty | Exercise | Enhanced Recovery After Surgery | Surgical Complication | Prehabilitation | Treatment Outcomes

Canada
Academisch Medisch Centrum - Universiteit van Amsterdam...
Patient-Led Research Collaborative Long COVID

Recruiting

Skeletal Muscle in PASC and ME/CFS Patients (MUSCLE-PASC)

ME/CFS | LONG-COVID | Post-acute Sequelae of COVID-19

Netherlands
Karolinska University Hospital

Recruiting

PET Imaging of Solid Tumors by a Novel Tracer, 68Ga-FAPI

Stomach Neoplasms | Pancreatic Neoplasms | Epithelial Ovarian Cancer | Bile Duct Neoplasms

Sweden
iOMEDICO AG

Recruiting

Registry Platform Ovarian and Endometrial Cancer (SMARAGD)

Carcinoma | Ovarian Cancer | Endometrial Neoplasms | Endometrial Cancer | Ovary Neoplasm | Neoplasm, Ovarian | Carcinoma, Ovarian

Germany
Haider Mahdi
Pfizer; Zenith Epigenetics

Recruiting

ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

United States
Sheikh Zayed Medical College

Recruiting

Efficacy of Nebulized Lidocaine, Salbutamol, and Beclomethasone Plus Salbutamol in the Covid-19 Patients With ARDS on Non-invasive Ventilation; Randomized Control Trial

COVID-19 Acute Respiratory Distress Syndrome

Pakistan
Mongi Slim Hospital

Not yet recruiting

Macintosh Versus Macgrath for Laryngoscopy in COVID 19 Hypoxemic ICU Patients

COVID-19 Acute Respiratory Distress Syndrome
Maimónides Biomedical Research Institute of Córdoba

Recruiting

Prevention and Treatment With Hydroxychloroquine + Azithromycin of Acute Respiratory Syndrome Induced by COVID-19 (AMBUCOV)

Covid19 | Acute Respiratory Distress Syndrome

Spain
Hospital Universitario Infanta Leonor
Kern Pharma, S.L.; Fundación para la Investigación e Innovación Biomédica del...

Recruiting

DEXamethasone EARLY Administration in Hospitalized Patients With Covid-19 Pneumonia (EARLYDEXCoV2)

COVID-19 | Pneumonia, Viral | Acute Respiratory Distress Syndrome

Spain
Daiichi Sankyo, Inc.

Recruiting

A Study of DS-6000a in Subjects With Advanced Renal Cell Carcinoma and Ovarian Tumors

Renal Cell Carcinoma | Ovarian Tumor

Japan, United States
Bobbie Jo Rimel, MD

Recruiting

Statin Therapy to Reduce Progression in Women With Platinum Sensitive Ovarian Cancer

Recurrent Ovarian Cancer | Platinum-sensitive Ovarian Cancer

United States
Baylx Inc.

Not yet recruiting

Use of hUC-MSC Product (BX-U001) for the Treatment of COVID-19 With ARDS

COVID-19 | Acute Respiratory Distress Syndrome | ARDS
Massachusetts General Hospital

Recruiting

Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients

Respiratory Distress Syndrome | Mechanical Ventilation Complication | Right Ventricular Dysfunction | ARDS, Human | Right Heart Failure | Lung Injury, Acute | Alveolar Edema

United States
University Hospital, Toulouse

Recruiting

Alveolar Recruitment Maneuvers, Intracerebral Hemodynamic and Oxygenation (M'RHICO)

Acute Respiratory Distress Syndrome (ARDS) | Cerebral Injuries

France
K-Group, Beta, Inc., a wholly owned subsidiary...

Active, not recruiting

A Study of ZN-c3 and Niraparib in Subjects With Platinum-Resistant Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Platinum-resistant Ovarian Cancer | Primary Peritoneal Carcinoma

United States, France
Imunon

Active, not recruiting

Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2) (OVATION 2)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

United States, Canada
Yale University
R-Pharm-US, LLC

Completed

Evaluation of Weekly Ixabepilone With or Without Biweekly Bevacizumab

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

United States
Pfizer

Terminated

Study of Maplirpacept (PF-07901801) in Combination With PLD in Patients With Platinum-Resistant Ovarian Cancer

Ovarian Neoplasms | Ovarian Cancer | Fallopian Tube Cancer | Epithelial Ovarian Cancer | Ovarian Carcinoma | Primary Peritoneal Carcinoma

United States
The Hospital for Sick Children
University of Alberta; University of Waterloo

Terminated

Metformin Treatment in Infants After Perinatal Brain Injury

Premature Birth | Hypoxic Ischemic Encephalopathy of Newborn

Canada
Children's Hospital Medical Center, Cincinnati

Completed

Eculizumab to Treat Thrombotic Microangiopathy/Atypical Hemolytic Uremic Syndrome -Associated Multiple Organ Dysfunction Syndrome in Hematopoietic Stem Cell Transplant Recipients

Thrombotic Microangiopathies | Atypical Hemolytic Uremic Syndrome | Multiple Organ Dysfunction Syndrome

United States
Peter MacCallum Cancer Centre, Australia

Active, not recruiting

BEACON - ABC in Recurrent Platinum Resistant HGSOC (BEACON)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma

Australia
AstraZeneca
British Columbia Cancer Agency

Completed

Phase II Study of AZD2281 in Patients With Known BRCA Mutation Status or Recurrent High Grade Ovarian Cancer or Patients With Known BRCA Mutation Status/ Triple Neg Breast Cancer

Breast Cancer | Ovarian Carcinoma

Canada
Sandoz

Completed

A Crossover Bioequivalence Study of Olaparib Tablets, 150 mg (Lek Pharmaceuticals d.d.) and Lynparza® (Olaparib) Tablets 150 mg (AstraZeneca Pharmaceuticals LP), in Patients With BRCA Mutated Ovarian Cancer, Recurrent Ovarian Cancer or Metastatic Breast Cancer

Breast Cancer | Ovarian Cancer

India
Peking Union Medical College Hospital

Completed

Single-cell Landscape of BALF in Patients With Severe ARDS and CARDS

Covid19 | ARDS: Acute Respiratory Distress Syndrome

China

Clinical Trials on Congenital Metabolic Disorder

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