Clinical Trials on Congential Malformations of Aortic Valve

Total 3935 results

Institut National de la Santé Et de la Recherche...

Recruiting

National Evaluation of Patients With PIK3CA-Related Overgrowth Spectrum (PROS) (COSY)

Vascular Malformations | PIK3CA-related Overgrowth Spectrum | Megalencephaly | Lymphatic Malformation | CLOVES Syndrome | Venous Malformation | Klippel Trenaunay Syndrome | MCAP | Macrodactyly

France
Vanderbilt University Medical Center
Edwards Lifesciences

Completed

A pragmatiC sTrategy to Promote actIVity and Enhance Quality of Life AFTER Transcatheter Aortic Valve Replacement

Aortic Valve Stenosis

United States
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Ministry of Health, Italy; Region Emilia-Romagna, Italy

Completed

Costs, Cognitive Abilities and Quality of Life After Transcatheter Aortic Valve Implantation and Surgical Aortic Valve Replacement (CCQ)

Aortic Valve Stenosis

Italy
Suez Canal University
National Research Centre, Egypt

Completed

Outcome of Preserved Mitral Valve Apparatus During Mitral Valve Replacement (EarlyOutcome)

Mitral Valve Replacement | Diseases of Mitral Valves | Abnormality of Mitral Valve Annulus (Disorder)

Egypt
Admedus Regen Pty Ltd.

Completed

CardioCel Tri-leaflet Repair Study (CTRS)

Aortic Stenosis | Aortic Insufficiency

Belgium
Sorin Group USA, Inc.

Completed

Freedom SOLO Stentless Heart Valve Study (SOLO)

Aortic Stenosis | Aortic Insufficiency

United States, Canada
University Hospital, Bordeaux

Completed

Cryoablation of Venous Vascular Malformations (CRYOMAV)

Venous Vascular Malformation

France
Murdoch Childrens Research Institute
Royal Children's Hospital; Peter MacCallum Cancer Centre, Australia

Not yet recruiting

A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (TARGET-VM)

Arteriovenous Malformations | Vascular Malformations | MAP2K1 Gene Mutation | PIK3CA-related Overgrowth Spectrum | Vascular Anomalies | Lymphangioma | Lymphatic Malformation | KRAS G12D | Venous Malformation | Vascular Anomaly | KRAS G12C | PI3K Gene Mutation | Slow-Flow Vascular Malformation | Fast-Flow Vascular... and other conditions

Australia
Hungarian Institute of Cardiology
Semmelweis University

Unknown

Frailty and Cognitive Function Assessment of TAVI Patients

Quality of Life | Aortic Valve Stenosis | Heart Valve Disease

Hungary
JenaValve Technology, Inc.
King's College London; Universitätsklinikum Hamburg-Eppendorf

Completed

JUPITER Study: Transapical Aortic Valve Implantation for Aortic Regurgitation (JUPITER)

Aortic Stenosis | Aortic Regurgitation | Aortic Insufficiency

Netherlands, United Kingdom, Switzerland, Germany
Peijia Medical Technology (Suzhou) Co., Ltd.

Recruiting

Safety and Effectiveness of TaurusTrio™ Heart Valve System in Patients With Severe Aortic Regurgitation (AR)

Aortic Regurgitation

China
Chengdu Silara Meditech Inc.

Not yet recruiting

To Evaluate Safety and Effectiveness of Transcatheter Aortic Valve System in Patients With Severe Aortic Insufficiency

Aortic Insufficiency
Lille Catholic University

Active, not recruiting

Health Data Warehouse on Aortic Insufficiency (EDS-AI)

Heart Valve Diseases | Aortic Insufficiency
Groupe Hospitalier Paris Saint Joseph

Active, not recruiting

Accuracy of Left Subclavian Regurgitation Evaluated by Ultrasound Doppler and 4D Flow MRI (SUBCLAR)

Aortic Regurgitation

France
Universitätsklinikum Hamburg-Eppendorf

Completed

Cardiac T1 Mapping Enables Risk Prediction of LV Dysfunction After Surgery for Aortic Regurgitation

Aortic Regurgitation
Florence Nightingale Hospital, Istanbul

Completed

Velocity Vector Imaging in Patients With Moderate-to-Severe Aortic Regurgitation

Aortic Regurgitation

Turkey
Clinical Hospital Centre Zagreb

Recruiting

Apixaban for the Prevention of Latent Biological Valve Thrombosis

Aortic Valve Replacement | Antithrombotic Therapy | Rapid Deployment Valves | Bioprosthetic Valve Thrombosis

Croatia
Meshalkin Research Institute of Pathology of Circulation

Completed

Study of Aortic Root Reimplantation Procedure (STAR)

Aortic Valve Insufficiency | Ascending Aortic Aneurism

Russian Federation
Wuhan Union Hospital, China

Not yet recruiting

Effects of Pioglitazone in Calcific Aortic Valve Disease

Aortic Valve Stenosis | Calcification of Aortic Valve
IRCCS Policlinico S. Donato

Not yet recruiting

Performance of Currently Available traNscaTHEter Aortic Valve Platforms in Inoperable Patients With Pure Aortic regurgitatiON of a Native Valve. The PANTHEON International Project. (PANTHEON)

Aortic Regurgitation

Italy
Nanjing First Hospital, Nanjing Medical University

Recruiting

Transcatheter Self-expandable Valve Implantation for the Treatment of Severe Native Aortic Regurgitation (SEASON-AR)

Aortic Valve Disease

China
HLT Inc.

Withdrawn

HLT® Meridian® TAVR Valve System Early Feasibility Study for Aortic Regurgitation (RIVAL - AR EFS)

Aortic Regurgitation

United States
JenaValve Technology, Inc.

Active, not recruiting

THE ALIGN-AR EFS TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

Aortic Regurgitation

United States, Germany, Netherlands
Biostable Science & Engineering

Completed

The HAART 300 Annuloplasty Ring Trial Extended Safety and Performance

Aortic Insufficiency

Germany, Czech Republic
Petrovsky National Research Centre of Surgery

Recruiting

Antibacterial Tactics Based on Presepsin Level in Thoracic Aorta Surgery Patients

Thoracic Aortic Aneurysm | Thoracic Aortic Dissection | Cardiac Valve Disease | Aortic Aneurysm and Dissection

Russian Federation
Michele De Bonis

Completed

LOng-Term Fate of Moderate Aortic Regurgitation Left Untreated at the Time of Mitral Valve Surgery

Mitral Regurgitation | Aortic Regurgitation

Italy
Queen Silvia Children's Hospital, Gothenburg, Sweden
Sahlgrenska University Hospital, Sweden; Swedish Heart Lung Foundation

Recruiting

Effect of Fetal Aortic Valvuloplasty on Outcomes (FASSprosp)

Aortic Valve Stenosis | Congenital Heart Disease | Hypoplastic Left Heart Syndrome | Fetal Cardiac Disorder

United States, Austria, Canada, Finland, Germany, Poland, Spain, Sweden
Atlantic Health System

Recruiting

Comparison Study of Echocardiography and Cardiovascular Magnetic Resonance Imaging in the Assessment of Mitral and Aortic Regurgitation

Mitral Regurgitation | Aortic Regurgitation

United States
Ospedale San Raffaele

Unknown

Expiratory Flow Limitation and Mechanical Ventilation During Cardiopulmonary Bypass in Cardiac Surgery

Mitral Regurgitation | Aortic Regurgitation

Italy
Claret Medical

Completed

Sentinel(TM) Post-Market Registry

Transcatheter Aortic Valve Replacement | Severe Symptomatic Calcified Native Aortic Valve Stenosis
Hospital Ruber Internacional
Zogenix, Inc.

Recruiting

Fenfluramine for the Treatment of Different Types of Developmental and Epileptic Encephalopathies: a Pilot Trial Exploring Epileptic and Non-epileptic Outcomes (FENDEEP)

Refractory Epilepsy | STXBP1 Encephalopathy With Epilepsy | SYNGAP1 Encephalopathy | Inv Dup(15) Encephalopathy | Multifocal or Bilateral Malformations of Cortical Development | Continuous Spike and Waves During Slow Sleep

Spain
Biostable Science & Engineering

Enrolling by invitation

HAART Annuloplasty Device Valve Repair Registry

Aortic Valve Insufficiency | Aortic Aneurysm

United States
Assistance Publique - Hôpitaux de Paris

Completed

Conservative Aortic Valve Surgery for Aortic Insufficiency and Aneurysms of the Aortic Root. CAVIAAR (CAVIAAR)

Aortic Valve Insufficiency | Aortic Aneurysm

France
Oslo University Hospital
Oslo Metropolitan University

Not yet recruiting

10-year Follow-up After Aortic Valve Replacement Surgery (AVR-10year)

Quality of Life | Aortic Stenosis | Anxiety | Depressive Symptoms
China National Center for Cardiovascular Diseases
China International Medical Foundation

Recruiting

The Effectiveness and Safety of Levosimendan in Patients With Severe Aortic Stenosis and Heart Failure Undergoing Transcatheter Aortic Valve Replacement

Heart Failure | Aortic Valve Stenosis | Transcatheter Aortic Valve Replacement | Cardiac Event | Safety Issues | Effect of Drug | Inotropic Agents

China
Assistance Publique - Hôpitaux de Paris
European Association of Cardiovascular Imaging

Recruiting

European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study (EACVI-MMVD)

Aortic Valve Stenosis | Aortic Valve Disease | Heart Valve Diseases | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Mitral Valve Stenosis | Aortic Valve Stenosis With Insufficiency | Tricuspid Valve Insufficiency | Mitral Valve Disease | Tricuspid Valve Disease | Mitral Valve Insufficiency and... and other conditions

France
Fundación Pública Andaluza para la Investigación...

Completed

Quality of Life After Ministernotomy Versus Full Sternotomy Aortic Valve Replacement (QUALITY-AVR)

Aortic Valve Stenosis | Aortic Valve Disease | Heart Valve Diseases

Spain
Fundacin Biomedica Galicia Sur

Recruiting

Single Antiplatelet Treatment With Ticagrelor or Aspirin After Transcatheter Aortic Valve Implantation (REAC-TAVI2)

Aortic Valve Stenosis | Severe Aortic Valve Stenosis | Transcatheter Aortic Valve Implantation (TAVI) | Transcatheter Aortic Valve Replacement (TAVR)

Spain
Edwards Lifesciences

Active, not recruiting

China S3: Safety and Effectiveness of Edwards Lifesciences SAPIEN 3 THV in the Chinese Population

Aortic Stenosis | Aortic Regurgitation | Symptomatic Aortic Stenosis

China
Hospital Israelita Albert Einstein

Completed

Fetoscopic Open Spina Bifida Repair Using the SAFER Technique

Chiari Malformation Type 2 | Myelomeningocele | Meningomyelocele | Open Spina Bifida | Chiari Malformation With Spina Bifida

Brazil
Han Yaling, MD

Recruiting

Effects of MICT on Cardiopulmonary Function in Patients After TAVI

Cardiac Rehabilitation | Valve Disease, Aortic

China
Duke University
Patient-Centered Outcomes Research Institute; American College of Cardiology; The Society of Thoracic Surgeons

Completed

Optimizing Health Outcomes in Patients With Symptomatic Aortic Valve Disease (PCORI-AVR)

Aortic Valve Disease

United States
Ventor Technologies

Unknown

Transapical Implantation of Ventor Embracer™ Valve in Patients With Severe Aortic Valve Disease

Aortic Valve Disease

Germany
Fakultas Kedokteran Universitas Indonesia

Unknown

Left Ventricular Reverse Remodeling In Aortic Valve Replacement With Single Strip Pericardium Versus Mechanical Valve

Aortic Stenosis | Aortic Valve Stenosis | Aortic Valve Calcification | Valve Stenoses, Aortic

Indonesia
JC Medical, Inc.

Completed

Safety & Efficacy of the J-Valve Ausper System in Patients With Severe Aortic Stenosis and/or Aortic Regurgitation

Aortic Valve Disease

China
Yonsei University

Recruiting

Prognostic Value of Soluble Urokinase-type Plasminogen Activator Receptor in Valvular Heart Disease

Severe Aortic Stenosis or Severe Aortic Regurgitation

Korea, Republic of
Harvard University Faculty of Medicine
National Institute of Neurological Disorders and Stroke (NINDS); Howard Hughes...

Recruiting

Human Epilepsy Genetics--Neuronal Migration Disorders Study

Epilepsy | Brain Malformation | Cognition Disorder | Neuronal Migration Disorder

United States
Yonsei University

Unknown

Impact of Perioperative Treatment With Intravenous Glutamine on Myocardial Protection in Cardiac Surgery Patients With Aortic Stenosis

Aortic Valve Stenois

Korea, Republic of
The Cleveland Clinic
National Space Biomedical Research Institute

Terminated

Three Dimensional Imaging and Wireless Technologies to Enhance Medical Care in Space

Aortic Stenosis | Aortic Valve Insufficiency

United States
Foldax, Inc

Active, not recruiting

Clinical Investigation for the Foldax Tria Aortic Heart Valve- India

Aortic Valve Stenosis | Aortic Valve Disease | Aortic Valve Insufficiency | Aortic Valve Calcification

India

Clinical Trials on Congential Malformations of Aortic Valve

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