Clinical Trials on Coronary Atherosclerotic Heart Disease in Canada

Total 4451 results

Canadian Medical and Surgical Knowledge Translation...
HLS Therapeutics, Inc

Completed

Generalizability of REDUCE-IT Results to People of South Asian Descent With Atherosclerotic Cardiovascular Disease in Canada (REDUCE-IT Canada SA)

Myocardial Infarction | Cardiovascular Diseases | Coronary Heart Disease | Atherosclerotic Cardiovascular Disease

Canada
Hoffmann-La Roche

Completed

A Study of the Effect of RO4607381 on Atherosclerotic Plaque in Patients With Coronary Heart Disease

Coronary Heart Disease

United States, Canada
AusculSciences Canada Inc.
Ottawa Heart Institute Research Corporation

Unknown

A Novel Non-Invasive Acoustic Diagnostic for the Diagnosis of Coronary Artery Disease The CAD-det Validation Study

Cardiovascular Diseases | Coronary Artery Disease | Atherosclerosis | Coronary Occlusion

Canada
Dr. Amer Johri
Lantheus Medical Imaging

Completed

Early Detection of Cardiovascular Disease (VIBE)

Myocardial Infarction | Vascular Diseases | Atherosclerosis | Acute Coronary Syndrome | Cardiac Disease | Atheroma

Canada
Sunnybrook Health Sciences Centre

Unknown

A Lead Rectangle to Lower the Operator's Radiation Exposure

Coronary Artery Disease | Atherosclerosis | Coronary Occlusion

Canada
Cardiology Research UBC
Provincial Health Services Authority

Terminated

Routine Versus Selective Use of FFR to Guide PCI (FFR-SELECT)

Acute Coronary Syndrome | Angina, Unstable | Coronary Atherosclerosis

Canada
Sanofi

Completed

STRADIVARIUS (Strategy To Reduce Atherosclerosis Development InVolving Administration of Rimonabant - the Intravascular Ultrasound Study)

Coronary Atherosclerosis

Canada, United States, Italy, Spain, Poland, Netherlands, Belgium, France, Australia
Centre hospitalier de l'Université de Montréal...
Opsens, Inc.

Completed

Assessing the Accuracy of the OptoWire DeuxTM in a Wire to Wire Comparison (ACCURACY)

Coronary Artery Disease | Atherosclerosis | Angina, Stable | Angina, Unstable | Coronary Stenosis | NSTEMI - Non-ST Segment Elevation MI | Atherosclerosis, Coronary

Canada
Innovaderm Research Inc.
Abbott; Montreal Heart Institute

Completed

Effect of Adalimumab on Vascular Inflammation in Patients With Moderate to Severe Plaque Psoriasis

Psoriasis | Coronary Atherosclerosis | Vascular Inflammation

Canada
Ottawa Heart Institute Research Corporation
Bristol-Myers Squibb; Sanofi

Completed

Trial of Clopidogrel After Surgery for Coronary Artery Disease (CASCADE Trial) (CASCADE)

Atherosclerosis

Canada
Hamilton Health Sciences Corporation
McMaster University; University of Ottawa

Completed

Vascular Access Decision Aid (VADAS)

Coronary Artery Disease | Atherosclerosis

Canada
Innovaderm Research Inc.
AbbVie

Completed

Cytokines and Vascular Inflammation in Psoriasis

Psoriasis | Coronary Atherosclerosis | Vascular Inflammation

Canada
Innovaderm Research Inc.
Abbott; Montreal Heart Institute

Completed

Trial on the Effect of Adalimumab on Vascular Inflammation in Patients With Psoriasis

Psoriasis | Coronary Atherosclerosis | Vascular Inflammation

Canada
Viron Therapeutics Inc

Terminated

Serp-1 for the Treatment of Acute Coronary Syndrome

Unstable Angina | Coronary Atherosclerosis | Coronary Restenosis

United States, Canada
Sanofi
Regeneron Pharmaceuticals

Completed

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Atherosclerotic Cardiovascular Disease

China, Hong Kong, Austria, Bulgaria, Norway, Peru, France, Japan, Spain, Lithuania, Philippines, Israel, Belgium, Croatia, Poland, Hungary, Chile, Mexico, Latvia, Singapore, Switzerland, Colombia, Greece, Ukraine, Turkey, Finland, United States and more
Montreal Heart Institute

Completed

Colchicine in Vascular Inflammation Assessed With PET Imaging (COLPET)

Atherosclerotic Vascular Disease

Canada
Novartis Pharmaceuticals
The Cleveland Clinic

Completed

Safety and Efficacy of Aliskiren on the Progression of Atherosclerosis in Coronary Artery Disease Patients (AQUARIUS)

Coronary Artery Disease (CAD) | Coronary Atherosclerosis

Italy, Spain, Hungary, Australia, United States, Belgium, Canada, Germany, France, Argentina, Poland
AstraZeneca
The Cleveland Clinic

Completed

CRESTOR Athero Imaging Head to Head IVUS Study (SATURN)

Coronary Atherosclerosis

United States, France, Italy, Mexico, Russian Federation, Poland, Netherlands, Canada, Argentina, Australia, Belgium, Hungary, Spain, Brazil
Innovaderm Research Inc.
Icahn School of Medicine at Mount Sinai; Montreal Heart Institute

Completed

Trial on Vascular Inflammation in Atopic Dermatitis

Atopic Dermatitis | Coronary Atherosclerosis | Vascular Inflammation

Canada
University Health Network, Toronto
University of Toronto

Withdrawn

Efficacy of Cardiac Rehab for Patients With Peripheral Artery Disease Versus Patients With Coronary Artery Disease

Vascular Diseases | Coronary Artery Disease | Peripheral Arterial Disease

Canada
Novartis Pharmaceuticals

Recruiting

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events (V-PLAQUE)

Coronary Artery Disease

United States, Italy, Spain, France, Korea, Republic of, Hungary, Japan, Argentina, China, India, Belgium, Switzerland, United Kingdom, Canada, Australia, Brazil, Chile, Ireland
Genentech, Inc.
BioInvent International AB

Completed

A Study to Evaluate the Safety, Tolerability, and Activity of Intravenous MLDL1278A in Patients on Standard-of-Care Therapy for Stable Atherosclerotic Cardiovascular Disease (GLACIER)

Atherosclerosis

United States, Canada
Icahn School of Medicine at Mount Sinai
Massachusetts General Hospital; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Completed

Cardiovascular Inflammation Reduction Trial - Inflammation Imaging Study (CIRT)

Atherosclerotic Cardiovascular Disease | Vascular Inflammation

United States, Canada
Canadian Collaborative Research Network
Schering-Plough

Completed

Effects of Ezetimibe Add-On to Statin Therapy on Adipokine Production in Obese and Metabolic Syndrome Patients With Atherosclerosis

Coronary Artery Disease | Obesity | Metabolic Syndrome

Canada
Biotronik, Inc.
Medstar Health Research Institute; Biotronik AG; Baim Institute for Clinical...

Completed

Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions (BIOFLOW-V)

Myocardial Ischemia | Coronary Artery Disease | Angina Pectoris | Acute Coronary Syndrome | Ischemic Heart Disease | Atherosclerosis, Coronary

Belgium, Israel, Spain, Korea, Republic of, United States, Switzerland, Germany, Canada, Netherlands, Hungary, Denmark, New Zealand, Australia
Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

Taiwan, United States, Spain, Argentina, China, Italy, Australia, France, Canada, Japan, Belgium, Denmark, Germany, Hungary, Israel, Austria, Korea, Republic of, Brazil, Mexico, Netherlands, Romania, United Kingdom, Greece, Czechia, India, Slovak... and more
Sanofi

Completed

Hexadecasaccharide (SR123781A) in Patients With Unstable Angina or Non-ST-Segment Elevation Myocardial Infarction (SHINE)

Coronary Atherosclerosis

Korea, Republic of, France, United States, Chile, Argentina, Australia, Brazil, Czech Republic, Russian Federation, Spain, Belgium, Canada, India, Mexico, Netherlands, Poland, Portugal, Turkey
Weill Medical College of Cornell University

Completed

COroNary CT Angiography Evaluation For Clinical Outcomes: An InteRnational Multicenter Registry (CONFIRM) (CONFIRM)

Coronary Artery Disease | Cardiovascular Disease | Atherosclerosis

United States, Austria, Italy, Switzerland, Korea, Republic of, Germany, Canada
GlaxoSmithKline

Completed

SB-480848 In Subjects With Coronary Heart Disease

Atherosclerosis

United States, Germany, Estonia, Spain, Argentina, Canada, France, Netherlands, Australia, Bulgaria, Romania, Hungary, Denmark, India, New Zealand, Pakistan
Dr. Amer Johri
Lantheus Medical Imaging

Recruiting

Carotid Intraplaque Neovascularization Combined With Stress Echo (CIRCE)

Myocardial Infarction | Cardiovascular Diseases | Atherosclerosis | Carotid Artery Diseases | Acute Coronary Syndrome | Ischemic Heart Disease

Canada
NewAmsterdam Pharma
Monash University

Recruiting

Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease (PREVAIL)

Atherosclerotic Cardiovascular Disease

United States, Israel, Italy, Spain, Canada, Czechia, Poland, China, Denmark, Netherlands, Finland, Japan, Australia, Hungary, Germany, Croatia, United Kingdom, Bulgaria, South Africa, Georgia, Jordan, Slovakia, Latvia
Ottawa Heart Institute Research Corporation

Completed

Utility of a Smart Phone Application in Assessing Radial Artery Patency - the CAPITAL iRADIAL Study

Coronary Heart Disease

Canada
Amgen

Active, not recruiting

Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial

Atherosclerotic Cardiovascular Disease

United States, Belgium, Spain, China, Korea, Republic of, Australia, Netherlands, Austria, Czechia, Taiwan, Italy, Portugal, Greece, Hong Kong, Hungary, United Kingdom, France, Bulgaria, Germany, Finland, Japan, Sweden, Canada, Denmark, Icelan... and more
Montreal Heart Institute
Fonds de la Recherche en Santé du Québec

Completed

Individualized Exercise Training Based on the Heart Rate Variability in Coronary Heart Disease Patient (HRV-Predict)

Coronary Artery Disease

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Canada

Completed

Family Heart Health Program: Randomized, Controlled Trial (FHHP-RCT)

Coronary Heart Disease

Canada
University of Toronto
Canadian Institutes of Health Research (CIHR); Quaker Oats Centre of Excellence...

Active, not recruiting

Meta-analysis of Oat Fiber and Cardiovascular Risk Reduction.

Cardiovascular Diseases | Coronary Heart Disease

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Varenicline Versus Transdermal Nicotine Patch for Smoking Cessation in Patients With Coronary Heart Disease

Coronary Heart Disease

Canada
Ottawa Heart Institute Research Corporation

Recruiting

Florbetaben for Imaging of Vascular Amyloid (FERMATA)

Stroke | Transient Ischemic Attack | Acute Coronary Syndrome | Atherosclerosis of Artery

Canada
Ottawa Heart Institute Research Corporation

Recruiting

Exercise Training in Women With Heart Disease (EXCEED)

Cardiovascular Diseases | Coronary Heart Disease

Canada
Ottawa Heart Institute Research Corporation
GE Healthcare

Recruiting

Cadmium-zinc-telluride (CZT) Imaging of Myocardial Blood Flow (MBF) (SPECT MBF) (SPECT MBF)

Coronary Heart Disease

Canada
Ottawa Heart Institute Research Corporation

Completed

E-health Intervention for Cardiac Rehabilitation (VCRP-RCT)

Coronary Heart Disease | Valve Disease, Heart

Canada
Unity Health Toronto
Applied Health Research Centre

Recruiting

Effect of Evolocumab on Saphenous Vein Graft Patency Following Coronary Artery Bypass Surgery (NEWTON-CABG)

Atherosclerosis | Coronary Artery Bypass Graft Surgery | Vein Occlusion

Canada, United States
Montreal Heart Institute

Completed

Periodization of Exercise Training in Patients With Coronary Heart Disease. (PERIOD)

Coronary Heart Disease | Healthy Control

Canada
Boston Scientific Corporation

Completed

PLATINUM Diversity

Coronary Artery Disease | Atherosclerosis

United States
Ottawa Heart Institute Research Corporation

Recruiting

Peer Support for Women With Heart Disease: Women@Heart

Coronary Heart Disease | Women's Health

Canada
Laval University
Quebec Heart Institute

Recruiting

Physiology and Residual Ischemia After Percutaneous Coronary Intervention (EASY-PRIPCI)

Coronary Artery Disease | Chest Pain | Angina Pectoris | Ischemic Heart Disease | Coronary Restenosis

Canada
University of Manitoba
WhiteWave Foods, Inc.

Completed

Efficacy of Sterol Enhanced Soy Beverage on Cholesterol Metabolism, Inflammation and Oxidative Status in Humans

Coronary Heart Disease

Canada
Ottawa Heart Institute Research Corporation

Terminated

Prophylactic Intra-coronary Adenosine to Prevent Post Coronary Artery Stenting Myonecrosis

Coronary Artery Disease | Coronary Artery Stenosis

Canada
Ottawa Heart Institute Research Corporation
Spartan Bioscience Inc.

Completed

ReAssessment of Anti-Platelet Therapy Using an InDividualized Strategy Based on GENetic Evaluation (RAPID GENE)

Acute Coronary Syndrome | Percutaneous Coronary Intervention | Stable Coronary Artery Disease

Canada
University of Alberta
Alberta Health services; Alberta Health & Wellness; Merck Frosst Canada Ltd.

Completed

The Alberta Vascular Risk Reduction Community Pharmacy Project: RxEACH (RxEACH)

Diabetes | Chronic Kidney Disease | Established Atherosclerotic Vascular Disease | Framingham Risk Score More Than 20 Percent

Canada

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