Clinical Trials on Coronary Syndrome in South Africa

Total 1803 results

Eli Lilly and Company
Daiichi Sankyo, Inc.

Completed

Treatment With Adenosine Diphosphate (ADP) Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE-ACS)

Acute Coronary Syndrome

United States, Puerto Rico
Sanofi
Bristol-Myers Squibb

Completed

Clopidogrel Optimal Loading Dose Usage to Reduce Recurrent EveNTs/Optimal Antiplatelet Strategy for InterventionS (CURRENT/OASIS7)

Acute Coronary Disease | Angina Unstable

United States, France, Canada, Brazil, Poland, Romania, Russian Federation, Germany, Italy, Netherlands, Sweden, Switzerland, Turkey, Bulgaria, Estonia, India, Malaysia, Singapore, Belgium, Czech Republic, Mexico, Argentina, Chile, Cr... and more
Abbott Medical Devices

Completed

SPIRIT V: Post-marketing Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System in Europe (SPIRIT V)

Coronary Artery Disease | Coronary Disease | Coronary Restenosis

Ireland, Netherlands, Singapore, Spain, China, Belgium, Switzerland, Thailand, Israel, Germany, New Zealand, United Kingdom, Italy, Malaysia, Canada, India, Austria, France, South Africa, Portugal, Czech Republic, Greece, Sweden
Amarnath, Rathna, M.D.

Unknown

Efficacy and Safety of Omega-3 Lipid Therapy in Pediatric Patients With Parenteral Nutrition-Associated Liver Disease

Cholestasis | Short Bowel Syndrome

United States
Novartis Pharmaceuticals

Completed

A Randomized, Double-blind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia Syndrome

Familial Chylomicronemia Syndrome (FCS)

South Africa, Spain, France, Germany, United Kingdom, United States, Canada, Netherlands
Clinical Hub for Interventional Research (CHOIR)
The University of New South Wales; Australian National University

Recruiting

Combined Evaluation of Epigenetic and Sensitising Therapy in AML and MDS (CELESTIAL-MDS)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

Australia
GlaxoSmithKline

Completed

A Study to Evaluate the Safety of 12 Weeks of Dosing With GW856553 and Its Effects on Inflammatory Markers, Infarct Size, and Cardiac Function in Subjects With Myocardial Infarction Without ST-segment Elevation (Solstice)

Acute Coronary Syndrome

United States, Netherlands, Canada, Germany, Australia, United Kingdom, India, Spain, Poland
Race Oncology Ltd
Astex Pharmaceuticals, Inc.

Withdrawn

A Study of Bisantrene Combined With Cytarabine or With Decitabine for Adult Subjects With Extramedullary AML and MDS (BISECT)

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Higher Risk Myelodysplastic Syndrome

Australia
University of Athens

Completed

Combined High Frequency Oscillation and Tracheal Gas Insufflation for Severe Acute Respiratory Distress Syndrome

Respiratory Distress Syndrome, Adult

Greece
Kaiser Permanente

Completed

Standardizing Emergency Work-ups Around Risk Data (STEWARD)

Chest Pain | Acute Coronary Syndrome | Risk Reduction

United States
Harokopio University
University of Thessaly; University of Ioannina; University of Patras; CitiesNet; ... and other collaborators

Recruiting

Lifestyle-related Early Detection and Intervention for Older Adults & Elderly at Risk for Metabolic Syndrome (GATEKEEPER)

Metabolic Syndrome

Greece
Janssen Research & Development, LLC
Harvard Medical School (HMS and HSDM); Bayer; Duke Clinical Research Institute

Completed

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome (GEMINI ACS 1)

Acute Coronary Syndrome

United States, France, Poland, Ukraine, Belgium, Spain, Argentina, Bulgaria, Russian Federation, Turkey, Japan, Canada, Netherlands, Korea, Republic of, Brazil, Australia, Hungary, Sweden, Czechia, Denmark
Gilead Sciences

Active, not recruiting

Pre-Exposure Prophylaxis Study of Lenacapavir and Emtricitabine/Tenofovir Alafenamide in Adolescent Girls and Young Women at Risk of HIV Infection (PURPOSE 1)

Pre-Exposure Prophylaxis of HIV Infection

South Africa, Uganda
Cadrock Pty. Ltd.
Centre for Digestive Diseases, Australia

Terminated

Anti-chlamydophila Antibiotic Combination Therapy in the Treatment of Patients With Coronary Heart Disease (ACAC-CHD)

Coronary Heart Disease | Chlamydophila Pneumoniae Infections

Australia
Abbott Medical Devices

Completed

Abbott Next Generation Drug Eluting Stent 48mm Study (SPIRIT 48)

Coronary Artery Disease

United States, Australia, Taiwan
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Vosaroxin and Infusional Cytarabine in Treating Patients With Untreated Acute Myeloid Leukemia (VITAL)

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Therapy-Related Acute Myeloid Leukemia | Therapy-Related Myelodysplastic Syndrome | Myeloid Sarcoma | Acute Myeloid Leukemia With Multilineage Dysplasia

United States
Population Health Research Institute

Completed

A Trial of Routine Aspiration Thrombectomy With Percutaneous Coronary Intervention (PCI) Versus PCI Alone in Patients With ST-Segment Elevation Myocardial Infarction (STEMI) Undergoing Primary PCI (TOTAL)

ST Elevation Myocardial Infarction | Acute Coronary Syndrome | Percutaneous Coronary Intervention

Canada, United States, Korea, Republic of, United Kingdom, Spain, New Zealand, France, Greece, Austria, Netherlands, Germany, Finland, Serbia, Czech Republic, Australia, Hungary, Brazil, Belgium, China, Macedonia, The Former Yugoslav...
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Study of Effects of Tenofovir on Bone Health and Kidneys During Pregnancy and Breastfeeding

HIV Infections

Malawi, South Africa, Zimbabwe, Uganda
National Heart, Lung, and Blood Institute (NHLBI)
National Cancer Institute (NCI)

Recruiting

The National Myelodysplastic Syndromes (MDS) Study (MDS)

Myelodysplastic Syndromes (MDS)

United States, Israel
Allergan

Completed

Safety and Efficacy Study of New Eye Drop Formulations With Refresh Tears® in Patients With Dry Eye Disease

Dry Eye Syndromes

Canada, Australia
Fairbanks Institute
Regenstrief Institute, Inc.; Indiana University School of Medicine; Richard M... and other collaborators

Unknown

Biorepository: Indiana Health Study (IHS)

Coronary Artery Disease | Healthy | Heart Disease

United States
Novartis Pharmaceuticals

Recruiting

A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease

Coronary Heart Disease

Canada, United States
Proaxis Therapy
Virginia Commonwealth University; Arcadia University; National Athletic Trainers...

Completed

Randomized Clinical Trial of Rehabilitation for Subacromial Impingement Syndrome

Shoulder Impingement Syndrome

United States
Erasmus Medical Center

Completed

PULsecath mechanicaL Support Evaluation (PULSE)

Coronary Artery Disease | Heart Failure | Cardiogenic Shock

France, Netherlands, United Kingdom
Infraredx

Terminated

CANARY: Coronary Assessment by Near-infrared of Atherosclerotic Rupture-prone Yellow (CANARY)

Myocardial Infarction | Coronary Atherosclerosis | Coronary Plaque Embolization

United States
Sanofi

Completed

The SEPIA-PCI Trial: Otamixaban in Comparison to Heparin in Subjects Undergoing Non-Urgent Percutaneous Coronary Intervention (SEPIA-PCI)

Angioplasty, Transluminal, Percutaneous Coronary

United States, Spain, Belgium, Canada, South Africa, Netherlands, Germany, France, Czech Republic, Slovakia
Mirati Therapeutics Inc.

Completed

Safety Study of Mocetinostat in Combination With Azacitidine in Subjects With MDS

Myelodysplastic Syndrome

United States
Abbott Medical Devices

Completed

SPIRIT PRIME Clinical Trial (SPIRIT PRIME)

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Coronary Restenosis | Coronary Artery Stenosis

United States, Australia
Microbicide Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Observational Study of HIV Infected Women Previously Enrolled in Other Microbicide Trials

HIV Infections

Malawi, Zimbabwe, Uganda, South Africa, Zambia
Sahajanand Medical Technologies Limited

Recruiting

S-FLEX Netherlands Registry: Prospective Evaluation of the Supraflex Family Sirolimus-eluting Coronary Stent System

Coronary Artery Disease

Netherlands
Keros Therapeutics, Inc.

Recruiting

A Study of KER-050 to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes

Myelodysplastic Syndromes | Cytopenia

Australia, Spain, United States, Israel, France, Germany, New Zealand, Czechia
PENTA Foundation
Institut National de la Santé Et de la Recherche Médicale, France; Program... and other collaborators

Active, not recruiting

A Randomised Trial of Dolutegravir (DTG)-Based Antiretroviral Therapy vs. Standard of Care (SOC) in Children With HIV Infection Starting First-line or Switching to Second-line ART

HIV Infection

United Kingdom, Spain, Portugal, South Africa, Thailand, Uganda, Germany, Zimbabwe
Abbott Medical Devices

Completed

Safety and Efficacy of the ZoMaxx™ Drug-Eluting Stent System in Coronary Arteries (ZoMaxx™ II)

Coronary Artery Disease | Coronary Disease | Coronary Restenosis

United States, Australia, New Zealand, Germany
Humanigen, Inc.

Suspended

Study of KB004 in Subjects With Hematologic Malignancies (Myelodysplastic Syndrome, MDS, Myelofibrosis, MF)

Myelodysplastic Syndrome (MDS) | Myelofibrosis (MF)

United States, Australia
Hoffmann-La Roche

Completed

A Study of Atezolizumab Administered Alone or in Combination With Azacitidine in Participants With Myelodysplastic Syndromes

Myelodysplastic Syndromes

United States
Amgen

Completed

Imaging of Coronary Plaques in Participants Treated With Evolocumab

Coronary Artery Disease (CAD)

Australia, Czechia, Italy, United States, Netherlands, Hungary, Germany
Imperial College London

Unknown

Functional Lesion Assessment of Intermediate Stenosis to Guide Revascularisation (DEFINE-FLAIR)

Coronary Artery Disease

United States, United Kingdom, Spain, Australia, Belgium, Egypt, Finland, Germany, Italy, Japan, Korea, Republic of, Latvia, Netherlands, Portugal, Saudi Arabia, South Africa, Turkey
International Partnership for Microbicides, Inc.

Completed

A Safety Study of Dapivirine Vaginal Ring in Africa

HIV Infections

South Africa, Tanzania, Malawi, Kenya
Universitas Sriwijaya

Active, not recruiting

Efficacy of Extra Virgin Olive Oil (EVOO) Supplementation on Hand-Foot Syndrome Incidence in Patients With Capecitabine (EVOO)

Capecitabine | Hand and Foot Syndrome | Hand and Foot Skin Reaction

Indonesia
Aileron Therapeutics, Inc.

Completed

Safety Study of ALRN-6924 in Patients With Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United States
University of Athens
Academy of Athens

Completed

Clinical and Biological Markers in Acute Respiratory Failure

Acute Respiratory Distress Syndrome | Ventilator-Associated Pneumonia

Greece
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); National Institute...

Completed

A Study of Dementia and Neurological Problems in HIV Infected Patients Who Are Participating in ACTG A5175

HIV Infections

South Africa, Brazil, Zimbabwe, India, Malawi
ViiV Healthcare
GlaxoSmithKline

Completed

Study Of An Investigational Regimen Including FDA Approved HIV Drugs In HIV-Infected Pediatric Subjects

HIV Infections | Infection, Human Immunodeficiency Virus

United States, Portugal, Russian Federation, Mexico, Argentina, South Africa, Puerto Rico
University of Athens
University of Thessaly

Terminated

High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS)

Acute Respiratory Distress Syndrome

Greece
Merck Sharp & Dohme LLC

Completed

Safety and Immunogenicity of V114 in Children Infected With Human Immunodeficiency Virus (HIV) (V114-030/PNEU-WAY PED) (PNEU-WAY PED)

Pneumococcal Infections

South Africa, Thailand, Ukraine
Abbott Medical Devices
Bristol-Myers Squibb; Eli Lilly and Company; Daiichi Sankyo, Inc.; Baim Institute...

Completed

XIENCE V® USA Dual Antiplatelet Therapy (DAPT) Cohort (XVU-AV DAPT)

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Chronic Total Occlusion of Coronary Artery | Coronary Restenosis | Vascular Disease | Coronary Artery Stenosis

United States
Scynexis, Inc.

Completed

Open-Label Study to Evaluate the Efficacy and Safety of Oral Ibrexafungerp (SCY-078) in Patients With Candidiasis Caused by Candida Auris (CARES) (CARES)

Candidemia | Candidiasis, Invasive

Pakistan, India, United States, South Africa
Otsuka Australia Pharmaceutical Pty Ltd

Active, not recruiting

A Study Comparing Treatment Preference Between Oral Decitabine/Cedazuridine and Azacitidine in Myelodysplastic Syndrome, Low-Blast Acute Myeloid Leukemia, or Chronic Myelomonocytic Leukemia (PREFER-HMA)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Leukemia, Myelomonocytic, Chronic | Patient Preference

New Zealand, Australia
University of Athens

Recruiting

Cerebral Autoregulation and COVID-19 (CA-COVID)

COVID-19 Pneumonia | COVID-19 Acute Respiratory Distress Syndrome

Greece
CardioDx

Withdrawn

Clinician Utilization of Corus CAD (or ASGES) in Primary Care Provider Decision Making (CU-PCP)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States

Clinical Trials on Coronary Syndrome in South Africa

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