Clinical Trials on Covid19, Vaccines in South Africa

Total 343 results

Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating a 13-valent Pneumococcal Conjugate Vaccine in Elderly Subjects

Vaccines, Pneumococcal Conjugate Vaccine

South Africa
PATH
Bill and Melinda Gates Foundation; Children's Hospital Medical Center, Cincinnati and other collaborators

Completed

Mixed Schedule Study of Live Oral Rotavirus Vaccines and Trivalent P2-VP8 Subunit Rotavirus Vaccine

Rotavirus Vaccine

South Africa
PATH

Completed

Phase I/II Descending Age Study of P2VP8 Subunit Parenteral Rotavirus Vaccine in Healthy Toddlers and Infants

Evaluation of a Rotavirus Vaccine

South Africa
HIV Vaccine Trials Network
South Africa AIDS Vaccine Initiative

Completed

Safety of and Immune Response to a DNA HIV Vaccine Boosted With a Modified Vaccinia HIV Vaccine and Protein HIV Vaccine in Healthy Adults

HIV Seronegativity | HIV Preventive Vaccine

South Africa
Providence Therapeutics Holdings Inc.

Completed

PTX-COVID19-B, an mRNA Humoral Vaccine, Intended for Prevention of COVID-19 in a General Population. This Study is Designed to Demonstrate the Safety, Tolerability, and Immunogenicity of PTX-COVID19-B in Comparison to the Pfizer-BioNTech COVID-19 Vaccine.

Covid19 Vaccine

Canada, South Africa
GlaxoSmithKline

Completed

Immunogenicity and Safety of a Candidate Tuberculosis (TB) Vaccine Given to Healthy Adults in a TB-endemic Region

Tuberculosis (TB) | Tuberculosis Vaccines

South Africa
ImmunityBio, Inc.

Active, not recruiting

COVID-19 Vaccination Using a 2nd Generation (E1/E2B/E3-Deleted) Adenoviral Platform in Healthy South African Adults

Covid19

South Africa
University of Cape Town
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV (BifIID)

Vaccine Reaction | Hiv | Microbial Colonization | Infant Development

South Africa
Pfizer

Completed

13vPnC Multidose Vial Safety, Tolerability and Immunogenicity Study in Healthy Infants.

Pneumococcal Vaccines

Gambia
University of Witwatersrand, South Africa
SynaVir

Completed

Study of Oral Administration of Ribavirin and Nitazoxamide Versus Placebo in COVID-19 (DuACT)

Covid19 | SARS-CoV Infection

South Africa
University of Witwatersrand, South Africa

Completed

COVID-19 Prophylaxis South Africa (COVER HCW) (COVER)

Covid19 | SARS-CoV Infection

South Africa
Desmond Tutu HIV Foundation
Amsterdam Institute for Global Health and Development; University of Cape Town and other collaborators

Completed

Transmission of Coronavirus Disease 2019 (COVID19) in Crowded Environments (TRACE)

Covid19 | Sars-CoV-2 Infection

South Africa
Shabir Madhi

Not yet recruiting

Pertussis Vaccination Among HIV-infected and HIV-uninfected Pregnant Women

dTap Vaccine

South Africa
Wits Health Consortium (Pty) Ltd
Perinatal HIV Research Unit of the University of the Witswatersrand; PharmaCentrix...

Terminated

PHRU CoV01 A Trial of Triazavirin (TZV) for the Treatment of Mild-moderate COVID-19 (PHRUCov01)

Covid19

South Africa
IDeA States Pediatric Clinical Trials Network
National Institutes of Health (NIH); University of Nebraska; University of Montana

Active, not recruiting

Improving Pediatric COVID-19 Vaccine Uptake Using an mHealth Tool (MoVeUP)

Telemedicine | Pediatric ALL | Vaccine Hesitancy | COVID-19 Vaccines

United States
Medical University of Graz
Lagos State University; Walter Sisulu University; Management Sciences for Health and other collaborators

Enrolling by invitation

Effects of COVID-19 on Endothelium in HIV-Positive Patients in Sub-Saharan Africa (ENDOCOVID)

Covid19 | Hiv | ART

Nigeria, South Africa
EyeGene Inc.
Novotech (Australia) Pty Limited

Active, not recruiting

Study to Assess the Safety, Tolerability and Explore the Immunogenicity of EG-COVID and EG-COVARo in Healthy Adult Volunteers

COVID-19 Vaccine

Australia
University of Liverpool
University of Southampton; Liverpool University Hospitals NHS Foundation Trust and other collaborators

Active, not recruiting

AGILE (Early Phase Platform Trial for COVID-19)

Covid19

United Kingdom, South Africa
Derek Yellon

Completed

Can RIC Prevent Deterioration to Critical Care in Covid19

Ischemia | Covid19

Brazil, South Africa, United Kingdom
University of Witwatersrand, South Africa

Active, not recruiting

A Cross-sectional, Observational Study to Characterise Long COVID-19 in an Urban Sample of South African Adults (ChaLOC)

Long COVID

South Africa
Clover Biopharmaceuticals AUS Pty Ltd

Completed

Safety and Immunogenicity Dose-finding Study of Adjuvanted SCB-2020S Vaccine in Adults

COVID-19

South Africa
GlaxoSmithKline
Aeras

Completed

Study to Evaluate the Efficacy of GlaxoSmithKline (GSK) Biologicals' Candidate Tuberculosis (TB) Vaccine in Adults

Tuberculosis | Tuberculosis Vaccines

South Africa, Kenya, Zambia
ImmunityBio, Inc.

Terminated

THEMBA II T-Cell Vaccine: Vaccination With saRNA COVID-19 Vaccines

COVID-19

South Africa
Shin Poong Pharmaceutical Co. Ltd.
Medicines for Malaria Venture

Completed

COVID-19 Treatment in South Africa

COVID-19

South Africa
The Aurum Institute NPC
Ludwig-Maximilians - University of Munich; Chris Hani Baragwanath Academic...

Completed

Tuberculosis as a Risk Factor for a Worse Outcome Post-Sars-CoV-2 Infection (Co-TB)

COVID-19 | Tuberculosis | Post-acute COVID-19 Syndrome

South Africa
Foundation for Innovative New Diagnostics, Switzerland

Completed

Novel Rapid POC Diagnostics for COVID-19

COVID-19 Respiratory Infection

Georgia, South Africa
Scancell Ltd

Active, not recruiting

A First Time in Human Phase 1 Open-Label Study of the COVIDITY Vaccine Administered by Needle-free Injection

COVID-19

South Africa
Code Pharma

Recruiting

Phase IIa Randomized Placebo Controlled Clinical Study of Codivir in Hospitalized Patients With Moderate COVID-19

COVID-19

South Africa
University of Cape Town

Withdrawn

Chloroquine Outpatient Treatment Evaluation for HIV-Covid-19 (CQOTE)

Covid-19 | HIV

South Africa
Desmond Tutu HIV Foundation
Karolinska Institutet; University of North Carolina, Chapel Hill; ViiV Healthcare and other collaborators

Completed

Bidirectional, Upbeat Communication and Differentiated, Distanced Care for Young People (BUDDY)

HIV Infections | Covid19 | Health Care Utilization | Gender-based Violence

South Africa
Sanofi Pasteur, a Sanofi Company

Completed

Study to Evaluate the Immune Response After Booster Vaccination With Tdap-IPV Vaccine (Against Tetanus, Diphtheria, Pertussis and Poliomyelitis) in Children Who Received Different Pertussis Primary Vaccine Regimens in Republic of South Africa

Pertussis Immunisation | Diphtheria Immunisation | Tetanus Immunisation | Poliomyelitis Vaccine

South Africa
University of Cape Town

Completed

Health System Dynamic & Resource Requirement in a South African COVID-19 Field Hospital

COVID-19 Pandemic | Low-Income Population | Global Health | Health Resources | Field Hospitals | Health Systems

South Africa
Duke University
University of South Carolina

Completed

Increase Vaccine Uptake in Adolescent in Rural South (INVEST)

Vaccine Hesitancy

United States
Shabir Madhi

Recruiting

Surveillance Among Healthcare Workers for SARS-Coronavirus-2 Infection

COVID-19 | SARS-CoV2 Infection

South Africa
IGM Biosciences, Inc.

Terminated

Evaluation of IGM-6268 in Healthy Adults and Patients With Mild to Moderate COVID-19

COVID-19 | Healthy Volunteers

South Africa
Pfizer

Completed

A Clinical Trial to Study the Safety, Tolerance and Immunogenic Response to MCV4, Tdap and Bivalent rLP2086 Vaccine When Given at the Same Time to Children Between the Ages of 10 Through 12 Years of Age

Vaccines | Meningococcal Vaccines

United States
AB Science

Recruiting

Masitinib in Patients With Symptomatic Mild to Moderate COVID-19

Covid19 | Coronavirus Disease 2019 | SARS-CoV2 Infection

France, Russian Federation, South Africa
Vaxcyte, Inc.

Completed

Safety, Tolerability, and Immunogenicity Study of a 24-Valent Pneumococcal Conjugate Vaccine (VAX-24) in Adults

Pneumococcal Vaccines

United States
Vaxcyte, Inc.

Completed

Safety, Tolerability, and Immunogenicity Study of a 24-Valent Pneumococcal Conjugate Vaccine (VAX-24) in Older Adults

Pneumococcal Vaccines

United States
McGill University Health Centre/Research Institute...
University of Cape Town Lung Institute

Recruiting

A Randomized Controlled Trial of a Digital, Self-testing Strategy for COVID-19 Infection in South Africa.

COVID-19

South Africa
Foundation for Innovative New Diagnostics, Switzerland

Completed

Evaluation of the Performance of Rapid Diagnostics for SARS-CoV-2 Self-testing in the Hands of Untrained (CV009)

COVID-19

South Africa, Uganda
Gritstone bio, Inc.

Completed

Study of Self-Amplifying Messenger Ribonucleic Acid (samRNA) Vaccines Against COVID-19 in Healthy Adults and People Living With Human Immunodeficiency Virus (HIV)

COVID-19 | SARS-CoV-2

South Africa
TASK Applied Science

Completed

BCG Vaccination for Healthcare Workers in COVID-19 Pandemic

COVID-19 | Sars-CoV2

South Africa
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Evaluate a 13-valent Pneumococcal Conjugate Vaccine in Infants.

Vaccines, Pneumococcal

Spain
Pfizer

Completed

A Clinical Trial to Study the Safety, Tolerance and Immunogenic Response to Gardasil and Bivalent rLP2086 Vaccine When Given at the Same Time to Children Between the Ages of 11 and 17

Vaccines | Meningococcal Vaccines

United States
Masaryk University
University of Kiel; University of Giessen; F.D. Roosevelt Teaching Hospital with... and other collaborators

Unknown

Oral Side Effects of COVID-19 Vaccine

Covid19 | Vaccine Adverse Reaction | Oral Manifestations

Czechia, Germany, Slovakia
Pfizer

Completed

Study Comparing 13-valent Pneumococcal Conjugate Vaccine With 7-valent Pneumococcal Conjugate Vaccine

Vaccines, Pneumococcal

United States
Klaus Reither
Radboud University Medical Center; Charite University, Berlin, Germany; University... and other collaborators

Completed

Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis (TB TRIAGE+)

Covid-19 | HIV | Pulmonary Tuberculosis | Tuberculosis Diagnosis

Lesotho, South Africa
Vaxcyte, Inc.

Active, not recruiting

Safety, Tolerability, and Immunogenicity Study of a 31-Valent Pneumococcal Conjugate Vaccine (VAX-31) in Adults

Pneumococcal Vaccines

United States
Thrombosis Research Institute
Sanofi

Terminated

Early Prophylactic Low-molecular-weight Heparin (LMWH) in Symptomatic COVID-19 Positive Patients (ETHIC)

COVID-19

Australia, Belgium, South Africa

Clinical Trials on Covid19, Vaccines in South Africa

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