Clinical Trials on Critical Illness Related Corticosteroids Insufficiency in South Africa

Total 96 results

Chris Hani Baragwanath Academic Hospital
Masimo Corporation

Completed

Usefulness of Non-invasive Pulse Co-oximetry Haemaglobin Measurements in Critically Ill Black Patients

Critically Ill Black Patients

South Africa
University of Stellenbosch
Fresenius Kabi

Recruiting

Effect of Combined IV Bolus Amino Acid Supplementation and Mobilisation on Muscle Mass in Patients Over the First Week of ICU Care: RCT

Critical Illness

South Africa
Australian and New Zealand Intensive Care Research...
Baxter Healthcare Corporation

Active, not recruiting

Intensive Nutrition in Critically Ill Adults (INTENT)

Critical Illness | Critically Ill

Australia, New Zealand
South West Sydney Local Health District

Completed

Fluid Responsiveness After CArdiac Surgery Study (FRACAS)

Critically Ill | Hypovolemia

Australia
Australian and New Zealand Intensive Care Research...

Active, not recruiting

INTENT-Muscle (A Sub-study of INTENT)

Critically Ill

Australia, New Zealand
Takeda
Theravance Biopharma

Completed

A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance

Enteral Feeding Intolerance

Australia
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia; Intensive Care National... and other collaborators

Completed

Treatment of Invasively Ventilated Adults With Early Activity and Mobilisation (TEAM(III))

Critically Ill, Mechanically Ventilated

Australia, New Zealand, United Kingdom, Ireland, Germany
Australian and New Zealand Intensive Care Research...
Monash University; The Alfred; St Vincent's Hospital, Sydney; Royal Prince Alfred... and other collaborators

Completed

Extracorporeal Membrane Oxygenation Physical Training (ECMO-PT)

Extracorporeal Membrane Oxygenation Complication | Critically Ill, Mechanically Ventilated

Canada, Australia
Daren K. Heyland
Ministry of Research, Innovation and Science, Ontario; Canadian Foundation...

Completed

PERFormance Enhancement of the Canadian Nutrition Guidelines by a Tailored Implementation Strategy: The PERFECTIS Study (PERFECTIS)

Critically Ill | Intensive Care Unit

Canada, United States
Hasanuddin University

Completed

High Protein Formula on Enteral Feeding in Clinical Improvement and Malnutrition at Intensive Care Unit Patients

Critically Ill | Intensive Care Unit

Indonesia
Erasmus Medical Center

Completed

Music for Anxiety in Critically Ill Patients (RELACS)

Anxiety

Netherlands
The George Institute

Completed

Fludrocortisone Dose Response Relationship in Septic Shock - FluDReSS (FluDReSS)

Septic Shock | Critically Ill

Australia
Duke University
Johns Hopkins University; National Institutes of Health (NIH); Vanderbilt University... and other collaborators

Terminated

DOSE Trial of Opioid Sparing Effect (DOSE)

Critically Ill | Dexmedetomidine | Mechanical Ventilation Complication

United States
GlaxoSmithKline

Completed

Evaluation of Single Doses of GSK962040 in Critically Ill Patients With Enteral Feed Intolerance

Gastroparesis

Australia
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia; Medical Research Institute... and other collaborators

Enrolling by invitation

The TEAM Long-Term Cohort Study (A Sub-study of TEAM(III))

Critically Ill | Mechanical Ventilation | Long Term Outcome

Australia
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia; The Alfred; National... and other collaborators

Recruiting

The EXCEL Registry of Patients Requiring ECMO

Cardiac Arrest | Critically Ill | Acute Respiratory Failure | Acute Heart Failure

Australia, New Zealand
GlaxoSmithKline

Terminated

Nutritional Adequacy Therapeutic Enhancement in the Critically Ill. The NUTRIATE Study

Gastroparesis

Canada, Australia, United States
Applied Physiology Pty Ltd
Trident Clinical Research Pty Ltd

Completed

Registration Enabling Study of the Safety and Efficacy of the Use of the Navigator Circulatory Management System (NAV-1)

Critical Illness | Intensive Care

Australia
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia

Completed

Early Goal-Directed Sedation Compared With Standard Care in Mechanically Ventilated Critically Ill Patients (SPICE III RCT)

Critical Illness and Mechanical Ventilation

Australia, United Kingdom, Italy, New Zealand, Malaysia, Ireland, Switzerland, Saudi Arabia
Australian and New Zealand Intensive Care Research...

Completed

The Augmented Versus Routine Approach to Giving Energy Trial (TARGET)

Critical Illness

Australia, New Zealand
The George Institute
National Health and Medical Research Council, Australia; University of British... and other collaborators

Completed

Normoglycaemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation (NICE - SUGAR STUDY)

Hyperglycemia | Critical Illness

Australia
Sunnybrook Health Sciences Centre

Completed

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE)

Sepsis | Mortality | Bacteremia | Critically Ill | Intensive Care | Antimicrobial

New Zealand, United States, Canada, Australia, Switzerland, Saudi Arabia, Israel
Millennium Pharmaceuticals, Inc.

Terminated

TAK-954 in Critically Ill Participants With Enteral Feeding Intolerance (EFI)

Critical Illness | Enteral Nutrition | Enteral Feeding Intolerance

United States, Canada, Australia, United Kingdom
Australian and New Zealand Intensive Care Research...

Recruiting

Indirect Calorimetry Guided Energy Provision in Critically Ill Patients With Obesity (DIRECT)

Obesity | Critical Illness

Australia
Australian and New Zealand Intensive Care Research...

Recruiting

Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults (BoneZone)

Critical Illness | Osteoporosis

Australia, New Zealand
McMaster University
Canadian Institutes of Health Research (CIHR); Australian and New Zealand Intensive... and other collaborators

Completed

PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT)

Critical Illness | Deep Venous Thrombosis

United States, Australia, Canada, Saudi Arabia, Brazil, United Kingdom
The George Institute
Sunnybrook Health Sciences Centre; Imperial College London

Completed

Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients (SuDDICU)

Sepsis | Critical Illness | Septic Shock | Ventilator Associated Pneumonia

Australia, Canada, United Kingdom
APR Applied Pharma Research s.a.
Cavendish Impact Foundation; Clinigen, Inc.; Nephron Pharmaceuticals, Inc.

No longer available

ZYESAMI (Aviptadil) Intermediate Population Expanded Access Protocol (SAMICARE) (SAMICARE)

Critical COVID-19 With Respiratory Failure

United States
Australian and New Zealand Intensive Care Research...
The Alfred

Completed

Recovery of Patients From COVID-19 After Critical Illness

COVID-19 | Critical Illness

Australia
Sheffield Children's NHS Foundation Trust

Completed

Neonatal, Infant and Toddler Salivary Study (NITS Study) (NITS)

Adrenal Insufficiency

United Kingdom
University of Ulster

Completed

Walking for Health: an Intervention to Increase Physical Activity and Reduce Sedentary Behaviour in People With SMI (WORtH)

Schizophrenia | Bipolar Disorder | Major Depression | Mental Illness | Psychosis

Ireland, United Kingdom
Critical Care Pharmacotherapy Trials Network
University of Arkansas

Completed

Drug Resistance Factors In Healthcare-associated Pneumonia (DEFINE)

Pneumonia | Critical Illness

United States, Saudi Arabia
VA Office of Research and Development

Completed

PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness) (PTSD/SMI)

Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Major Depression | Post Traumatic Stress Disorder

United States
Takeda

Withdrawn

Fasiglifam in Type 2 Diabetic Subjects With Chronic Kidney Disease Stage 4 or 5 on Hemodialysis

Type 2 Diabetes Mellitus | Chronic Kidney Disease

United States, Ukraine, Bulgaria, South Africa, Hungary, Slovakia, Poland
Massachusetts General Hospital

Completed

Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery (ASTER)

Sepsis | Critical Illness | Respiratory Failure | Acute Respiratory Distress Syndrome

United States
Cardiff University

Completed

Determination of Method-specific Normal Cortisol and Adrenal Hormone Responses to the Short Synacthen Test

Healthy | Hypopituitarism | Adrenal Insufficiency

United Kingdom
The University of Queensland
Baxter Healthcare Corporation; Health Research Council, New Zealand; Australian...

Completed

Better Evidence for Selecting Transplant Fluids (BEST-Fluids)

End Stage Kidney Disease | Kidney Transplant; Complications | Delayed Graft Function

Australia, New Zealand
AstraZeneca

Recruiting

iCaReMe Global Registry (iCaReMe)

Heart Failure | Hypertension | Type 2 Diabetes | Chronic Kidney Disease

Greece, Peru, Mexico, Costa Rica, Ecuador, Egypt, Ghana, India, Indonesia, Kenya, Nigeria, Philippines, South Africa
University of South Carolina
National Institute of Nursing Research (NINR)

Recruiting

Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads

Cardiovascular Diseases | Stroke | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Disease | SARS- CoV-2

United States
Eli Lilly and Company

Completed

A Study Comparing Dulaglutide With Insulin Glargine on Glycemic Control in Participants With Type 2 Diabetes (T2D) and Moderate or Severe Chronic Kidney Disease (CKD) (AWARD-7)

Type 2 Diabetes | Chronic Kidney Disease

Mexico, United States, Hungary, Ukraine, Brazil, Spain, Romania, South Africa, Poland
Cardiff and Vale University Health Board

Completed

Identifying Risk Factors for Developing AKI in Sepsis

Sepsis | Acute Kidney Injury | Diabetic Ketoacidosis

United Kingdom
AbbVie

Terminated

A Study of Creon (Pancrelipase) in Resected and Non-resected Pancreatic Cancer Participants With Exocrine Pancreatic Insufficiency (EPI)

Exocrine Pancreatic Insufficiency (EPI)

United States
AbbVie (prior sponsor, Abbott)

Completed

Long-Term Therapy Outcomes When Treating Chronic Kidney Disease (CKD) Patients With Paricalcitol in German and Austrian Clinical Practice (TOP)

Secondary Hyperparathyroidism | Kidney Insufficiency

Austria, Germany
Novo Nordisk A/S

Active, not recruiting

A Research Study to Find Out How Semaglutide Works in the Kidneys Compared to Placebo, in People With Type 2 Diabetes and Chronic Kidney Disease (the REMODEL Trial) (REMODEL)

Diabetes Mellitus, Type 2 | Chronic Kidney Disease

Spain, United States, Italy, Denmark, Poland, South Africa, Canada, France
Boehringer Ingelheim

Completed

Safety and Efficacy in Type 2 Diabetic Patients With Severe Chronic Renal Impairment, 5 mg BI 1356 (Linagliptin) vs. Placebo, Insulin Background Inclusive

Diabetes Mellitus, Type 2

United States, Australia, Hong Kong, Israel, New Zealand, Ukraine
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical Tumor

Stage I Adrenal Cortical Carcinoma AJCC v7 | Stage II Adrenal Cortical Carcinoma AJCC v7 | Stage III Adrenal Cortical Carcinoma AJCC v7 | Stage IV Adrenal Cortical Carcinoma AJCC v7

United States, Canada, Australia, Brazil
Amgen

Completed

Treatment of Autonomous Hyperparathyroidism in Post Renal Transplant Recipients

Hyperparathyroidism | End Stage Renal Disease | Chronic Kidney Disease | Kidney Transplantation | Chronic Renal Failure | Hypophosphatemia | Kidney Disease | Chronic Allograft Nephropathy | Disordered Mineral Metabolism | Post Renal Transplantation

United States, Canada, France, Italy, Belgium, Switzerland, Spain, Australia, Germany, Austria, Poland
AbbVie (prior sponsor, Abbott)

Completed

A Study of Atrasentan on Reducing Albuminuria in Type 2 Diabetic Nephropathy Treated With Renin-Angiotensin System Inhibitors

Diabetic Nephropathy | Chronic Kidney Disease

United States, Puerto Rico
Medical University of South Carolina

Completed

Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence (MUSTCOOL)

Diabetic Foot | Foot Ulcer | Leg Ulcer | Venous Insufficiency | Varicose Ulcer | Venous Ulcer | Venous Stasis Ulcer | Venous Hypertension Ulcers

United States
Amgen

Completed

Efficacy and Safety of Etelcalcetide (AMG 416) in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease (CKD) on Hemodialysis

Hyperparathyroidism, Secondary

United States, Belgium, Canada, France, Australia, Israel, Czechia, Hungary, Netherlands, Spain, Poland, Russian Federation, Italy, Sweden, Germany

Clinical Trials on Critical Illness Related Corticosteroids Insufficiency in South Africa

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CROs in United Arab Emirates

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