Clinical Trials on Cystic Fibrosis Lung

Total 59985 results

Stanford University

Terminated

Controlled Ventilation CT in CF Infants

Cystic Fibrosis

United States
AlgiPharma AS
Eurostars; Smerud Medical Research International AS

Completed

A Phase IIb Study of OligoG in Subjects With Cystic Fibrosis (SMR-2984)

Cystic Fibrosis

United Kingdom, Denmark, Norway, Germany, Sweden
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation

Cystic Fibrosis

United States, Canada, Germany, United Kingdom
Unity Health Toronto

Completed

HFN Versus NIV in Cystic Fibrosis. The HIFEN Study

Cystic Fibrosis

Canada
Corbus Pharmaceuticals Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Efficacy of JBT-101 (Lenabasum) in Cystic Fibrosis

Cystic Fibrosis

Belgium, United States, United Kingdom, Italy, France, Germany, Poland
Horizon Pharma USA, Inc.

Completed

"Safety, Tolerability and Pharmacokinetics of MP-376 Administered for 14 Days to Stable Pediatric (CF) Patients"

Cystic Fibrosis

United States
Joseph Pilewski
Cystic Fibrosis Foundation

Completed

Effects of Inhaled Bicarbonate on Airway pH in Cystic Fibrosis

Cystic Fibrosis

United States
Hadassah Medical Organization

Completed

Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF)

Cystic Fibrosis

Israel
University of Zurich
University of Manchester

Completed

Developing and Validating a Patient-reported Outcome Instrument to Monitor Symptom Management in Pulmonary Exacerbation in CF

Cystic Fibrosis

Switzerland
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Efficacy and Safety of Lumacaftor in Combination With Ivacaftor in Subjects With CF, Homozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United States, France, United Kingdom, Germany, Belgium, Australia, Denmark, Canada, Sweden
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

Early Intervention in Cystic Fibrosis Exacerbation (eICE)

Cystic Fibrosis

United States
University of Pittsburgh
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Imaging Airway Liquid Absorption in Cystic Fibrosis

Cystic Fibrosis

United States
University of Pittsburgh

Completed

Absorptive Clearance in the Cystic Fibrosis Airway

Cystic Fibrosis

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Using MRI to Observe Lung Changes in Infants With CF Compared to Infants Without CF (MRIinfantCF)

Cystic Fibrosis

United States
Royal Brompton & Harefield NHS Foundation Trust

Terminated

The Addition of Non-Invasive Ventilation To Airway Clearance Techniques In Adults With Cystic Fibrosis (NIV)

Cystic Fibrosis

United Kingdom
Assistance Publique - Hôpitaux de Paris
Vaincre la Mucoviscidose

Completed

Ivacaftor in French Patients With Cystic Fibrosis and a G551D Mutation (IVACAFTOR1)

Cystic Fibrosis

France
University of Colorado, Denver
Cystic Fibrosis Foundation; Yasoo Health

Completed

Effects of an Antioxidant-Enriched Multivitamin Supplement on Inflammation and Oxidative Stress in Cystic Fibrosis (AquADEKs-2)

Cystic Fibrosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Tissue Collection From People With Cystic Fibrosis

Cystic Fibrosis

United States
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Using Remote Telemonitoring to Detect Early Decline in Lung Function & Streamline Clinics in Adults With Cystic Fibrosis (RIGHT-CF)

Cystic Fibrosis

United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

Study of Lumacaftor in Combination With Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United States, Canada
University of Zurich

Completed

Exercise and Oscillatory Positive Expiratory Pressure Therapy in Cystic Fibrosis

Cystic Fibrosis

Switzerland
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; Hill-Rom

Completed

High Frequency Chest Wall Oscillation and Cystic Fibrosis

Cystic Fibrosis

United Kingdom
Nivalis Therapeutics, Inc.

Completed

Study of N91115 in Patients With Cystic Fibrosis Homozygous F508del-CFTR Mutation (SNO4)

Cystic Fibrosis

United States
Emma Wells
Manchester University NHS Foundation Trust

Completed

Investigating the Use of a Positive Parenting Programme to Improve Treatment Adherence in Cystic Fibrosis

Cystic Fibrosis
University Hospital, Montpellier

Completed

Early Assessment of Respiratory Function, Inflammation and Bronchial Reshuffle Among Newborns Screened for Cystic Fibrosis

Cystic Fibrosis

France
Karolinska University Hospital

Completed

Non Invasive Ventilation During Physical Training in Cystic Fibrosis

Cystic Fibrosis

Sweden
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

An Ocular Safety Study of Ivacaftor-Treated Pediatric Patients 11 Years of Age or Younger With Cystic Fibrosis

Cystic Fibrosis

United States
University of Arkansas
Arkansas Children's Hospital Research Institute

Completed

Assessment of Fat Free Mass Index and Its Impact on Health in Children With Cystic Fibrosis (GAIA)

Cystic Fibrosis

United States
Novartis Pharmaceuticals

Completed

Ease of Use and Microbial Contamination of Tobramycin Inhalation Powder (TIP) Versus Nebulised Tobramycin Inhalation Solution (TIS) and Nebulised Colistimethate (COLI)

Cystic Fibrosis

Spain, Germany, Switzerland, United Kingdom, Ireland
Elias Matouk

Completed

Safety Study of Fenretinide in Adult Patients With Cystic Fibrosis

Cystic Fibrosis

Canada
Novartis Pharmaceuticals

Completed

Study to Validate the Instructions for Use of TOBI® Podhaler™ in Cystic Fibrosis Patients

Cystic Fibrosis

United States
Great Ormond Street Hospital for Children NHS Foundation...

Completed

The iStep Study: Development and Validation of an Incremental Exercise Step Test for Children With Cystic Fibrosis

Cystic Fibrosis

United Kingdom
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

Study of Ivacaftor in Cystic Fibrosis Subjects 2 Through 5 Years of Age With a CFTR Gating Mutation

Cystic Fibrosis

United States, United Kingdom, Canada
Imperial College London

Completed

The Infective Pulmonary Exacerbations in Cystic Fibrosis - an Ecological Perspective

Cystic Fibrosis

United Kingdom
Stanford University

Completed

Comparison of the Airway Clearance Efficacy of Electro Flo 5000 and the G5 Flimm-Fighter in Patients With CF

Cystic Fibrosis
Imperial College London
University of Oxford; University of Edinburgh; Royal Brompton & Harefield NHS...

Completed

Repeated Application of Gene Therapy in CF Patients

Cystic Fibrosis

United Kingdom
Queen Fabiola Children's University Hospital

Completed

Omega 3 Supplementation in Cystic Fibrosis Patients

Cystic Fibrosis

Belgium
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-809 Alone and in Combination With VX-770 in Cystic Fibrosis (CF) Patients Homozygous or Heterozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United States, France, United Kingdom, Germany, Australia, New Zealand, Belgium
University Hospital, Tours

Completed

Induction of Neutrophilic Traps ( NETs ) by the Environment and Infectious Inflammatory Lung Cystic Fibrosis (MucoNETs)

Cystic Fibrosis

France
University Hospital, Strasbourg, France

Completed

Improvement of Aerobic Capacity in Cystic Fibrosis Patients With a One-year Home Training Period

Cystic Fibrosis

France
Federico II University

Completed

Probiotics in Cystic Fibrosis

Cystic Fibrosis

Italy
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Terminated

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Homozygous for the F508del-CFTR Mutation (DISCOVER)

Cystic Fibrosis

United States
Liverpool Heart and Chest Hospital NHS Foundation...

Completed

Investigating the Incretin Effect in Cystic Fibrosis (IECF)

Cystic Fibrosis

United Kingdom
Texas A&M University
Arkansas Children's Hospital Research Institute

Completed

Leucine-enriched Essential Amino Acid Intake to Optimize Protein Anabolism in Children With Cystic Fibrosis

Cystic Fibrosis

United States
University of Michigan

Completed

Exploring Novel Interventions to Improve Adherence in Children With Cystic Fibrosis

Cystic Fibrosis

United States
University of Alabama at Birmingham

Completed

Comprehensive Exercise Training Program During Hospitalization for an Acute CF Exacerbation

Cystic Fibrosis

United States
Assistance Publique - Hôpitaux de Paris
Vaincre la Mucoviscidose

Terminated

Oxygen Therapy in Cystic Fibrosis (MUCOXY)

Cystic Fibrosis

France
Vertex Pharmaceuticals Incorporated

Completed

Pilot Study Testing the Effect of Ivacaftor on Lung Function in Subjects With Cystic Fibrosis and Residual CFTR Function

Cystic Fibrosis

United States
Merck Sharp & Dohme LLC

Completed

A Safety and Tolerability Study of Denufosol in 2-4 Year Olds (REACH-1)

Cystic Fibrosis
Universitaire Ziekenhuizen KU Leuven

Completed

Sputum Purulence as a Predictor of Cystic Fibrosis Exacerbations: a Prospective Cohort Trial. (MucoSpuCo)

Cystic Fibrosis

Belgium

Clinical Trials on Cystic Fibrosis Lung

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