Clinical Trials on DNA Methylation

Total 23088 results

Chen Zi-Jiang
Chinese Academy of Sciences

Completed

Preimplantation DNA Methylation Test (PIMT) in ART

DNA Methylation

China
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Unknown

Comparison of the Methylation Pattern of DNA in Buccal Swabs From Different Time Points

DNA Methylation

Belgium
Medical Research Council

Completed

Methyl-Donors and EpiGenetics in The Gambia (MDEG)

Aberrant DNA Methylation
University of Colorado, Boulder
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

DNA Methylation and Cancer Prevention: Duration and Intensity of Exercise (GEM)

DNA Methylation

United States
Cancer Council Victoria

Completed

DNA Methylation and 1-C Metabolism Nutrient Intake

DNA Methylation
Shandong University
The First Affiliated Hospital with Nanjing Medical University; Changhai Hospital and other collaborators

Recruiting

First Live Birth Rate With eSET After Preimplantation Methylome Screening (PIMS) Versus Conventional In-vitro Fertilization

Reproductive Techniques, Assisted | DNA Methylation

China, Thailand
University of Sao Paulo General Hospital
Federal University of São Paulo

Completed

Effects of Mindfulness-based Intervention on Epigenetic Mechanisms, Cognition Function, Stress Response, and Well-being

Stress | DNA Methylation | Mindfulness | Psychological Well-being | Learning and Memory

Brazil
Chang Gung Memorial Hospital

Completed

Epigenetic Regulation of BDNF in Schizophrenia

BDNF, DNA Methylation, Suicide, Drug Responses.

Taiwan
Sun Yat-sen University
The First Affiliated Hospital of Anhui Medical University; Peking University... and other collaborators

Recruiting

PaCIFiC-CUP Classifies Cancer of Unknown Primary

Unknown Primary Tumors | DNA Methylation

China
Istanbul University - Cerrahpasa (IUC)
Scientific Research Project Coordination Unit of Istanbul University-Cerrahpasa

Active, not recruiting

LINE-1 and Alu Methylation Levels Among Middle Aged Women With Low Cardiovascular Risk Profile in Respect of Menopausal Hot Flashes

Cardiovascular Diseases | Hot Flashes | Sleep | Menopause | Epigenetics | DNA Methylation

Turkey
Jinling Hospital, China

Unknown

Comprehensive DNA Methylation Profiling in Crohn's Disease

Crohn Disease | Methylation | Illumina Human Methylation 850k BeadChip

China
SEAMEO Regional Centre for Food and Nutrition
London School of Hygiene and Tropical Medicine; University of Aberdeen

Not yet recruiting

Methylation, mIcrobiome, NUtritional sTatus, and dEvelopment of Stunted Children (MINUTES)

Stunting | Nutrition | Epigenetics | DNA Methylation | Development, Child
National Cancer Institute (NCI)

Completed

Diet and Nutrition Pilot Study for Chinese Adolescents and Their Mothers

Physical Activity | Body Composition | Puberty | Methylation

China
University Medical Centre Maribor

Recruiting

The Role of FAM19A4 and Hsa-mir-124 Methylation in Predicting Prognosis of Untreated Cervical Intraepithelial Neoplasia 2 (CIN 2)

Cervical Intraepithelial Neoplasia Grade 2 | DNA Methylation

Slovenia
WEIDONG LIU，MD
Natural Science Foundation of Hunan Province

Unknown

Analysis of Intestinal Microflora Combined With DNA Methylation in Stool to Detect Colorectal Cancer (IMMDC)

Colorectal Neoplasms | Gastrointestinal Microbiome | DNA Methylation

China
Ole Thorlacius-Ussing, MD, DMSc, Professor of Surgery

Unknown

Diagnostic Potential of Hypermethylated DNA in Colorectal Cancer

Colorectal Neoplasms | Aberrant DNA Methylation

Denmark
Mahidol University

Completed

DNA Methylation Biomarker for Diagnosis of Cholangiocarcinoma in Patients With Bile Duct Stricture (DNA)

Cholangiocarcinoma | Biliary Stricture | DNA Methylation | Brush Cytology

Thailand
University of Sao Paulo

Completed

Epigenetics in PostOperative Pediatric Emergence Delirium (EPOPED)

Postoperative Complications | Emergence Delirium | DNA Methylation

Brazil
Zhaoshen Li

Recruiting

Construction of Molecular Diagnostic Marker Model for Pancreatic Cystic Tumors Based on Pancreatic Cystic Fluid Samples

Pancreatic Neoplasms | DNA Methylation | Proteome

China
Centre Hospitalier Universitaire de Besancon

Completed

Analysis of DNA Methylation in Spondyloarthritis (METYLAS)

Spondylitis, Ankylosing | DNA Methylation | Axial Spondyloarthritis

France
Lei Li
The Third Xiangya Hospital of Central South University; Women's Hospital School... and other collaborators

Recruiting

DNA CDO1 and CELF4 Methylation for Endometrial Cancer Screening

Endometrial Cancer | DNA Methylation | Cancer Screening | Cervical Cytology | Testing Accuracy

China
Fudan University
RenJi Hospital; Hebei Medical University Fourth Hospital; Shanghai University... and other collaborators

Recruiting

Dynamic Monitoring of ctDNA Methylation to Predict Relapse in Colorectal Cancer After Radical Resection (POSTCA)

Colorectal Cancer | Circulating Tumor DNA | Surveillance | Methylation

China
Ana Flávia Marçal Pessoa
Federal University of São Paulo

Completed

BDNF Promoter Methylation: Effects on Cognition, Stress and Anxiety and Depression Symptom in Healthy Women. (BDNFm)

Stress | Well-being | Memory Impairment | Methylation | BDNF

Brazil
Fudan University

Recruiting

Circulating Tumor DNA Methylation Guided Postoperative Follow-up Strategy for Non-metastatic Colorectal Cancer

Non-metastatic Colorectal Cancer | Circulating Tumor DNA Methylation

China
Lei Li
Beijing Qiyuanjuhe Biotechnology Co., Ltd

Recruiting

Host DNA Methylation for Endometrial Cancer Screening

Endometrial Cancer | Cohort Study | Liquid Biopsy | DNA Methylation | Cancer Screening | Cervical Cytology

China
Lei Li

Unknown

DNA Methylation Testing for the Screening of Uterine Cervical Lesion

Cervical Cancer | Cervical Intraepithelial Neoplasia | DNA Methylation | Cytology | High-risk Human Papillomavirus

China
Seoul National University Hospital

Completed

Aberrant DNA Methylation to Predict Metachronous Gastric Neoplasms

Gastric Cancer | Metachronous Neoplasm | Gastric Neoplasm | Aberrant DNA Methylation
Lei Li

Unknown

Cell-free DNA Methylation for Endometrial Cancer

Endometrial Cancer | Liquid Biopsy | DNA Methylation | Diagnostic Accuracy | Cervical Cytology | Training Set | Validation Set

China
Fudan University

Recruiting

Circulating Tumor DNA Methylation Guided Postoperative Adjuvant Chemotherapy for High-risk Stage II/III Colorectal Cancer

Stage III Colorectal Cancer | High-risk Stage II Colorectal Cancer | Circulating Tumor DNA Methylation

China
Centre Hospitalier Universitaire, Amiens

Recruiting

Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity (EPSACO)

Biomarkers | Epigenetics | Oral Squamous Cell Carcinoma | DNA Methylation | Saliva | Maxillo-facial Surgery

France
Peking Union Medical College Hospital
Second Affiliated Hospital, School of Medicine, Zhejiang University; Zhejiang...

Recruiting

DNA PAX1 and JAM3 Methylation for Cervical Cancer Screening

Cervical Cancer | Cervical Intraepithelial Neoplasia | DNA Methylation | Cancer Screening | Detection Accuracy

China
The Affiliated Nanjing Drum Tower Hospital of Nanjing...
Peking Union Medical College Hospital; Shanghai Chest Hospital; Guangzhou Panyu... and other collaborators

Not yet recruiting

The Red Blood Cells Based Blood Test for Lung Cancer EARLY Detection

Lung Cancer | Methylation | Red Blood Cells
Lei Li

Unknown

Cell-free DNA Methylation for Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | Liquid Biopsy | DNA Methylation | Benign Ovarian Tumor | Training Set | Validation Set | Cell-free DNA

China
Lei Li

Recruiting

ctDNA Methylation for Detecting Ovarian Cancer

Epithelial Ovarian Cancer | Circulating Tumor DNA | CA125 | DNA Methylation | Non-invasive Diagnosis | Human Epididymis Protein 4 | Imaging Evaluation | Survival Prognosis | ROMA Index

China
Lei Li

Unknown

DNA Methylation for Screening Uterine Cervical Lesions

DNA Methylation | Uterine Cervical Cancer | High Grade Squamous Intraepithelial Lesions | Low Grade Squamous Intraepithelial Lesions

China
Lei Li

Unknown

DNA Methylation for Screening Uterine Cervical Lesions: A Case-control Study

DNA Methylation | Uterine Cervical Cancer | High Grade Squamous Intraepithelial Lesions | Low Grade Squamous Intraepithelial Lesions

China
Lei Li

Recruiting

ctDNA Methylation for Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | Circulating Tumor DNA | CA125 | DNA Methylation | Non-invasive Diagnosis | Human Epididymis Protein 4 | Imaging Evaluation | Survival Prognosis

China
National Taiwan University Hospital

Recruiting

The Utility of Cell-free DNA Methylation Markers for Hepatocellular Carcinoma

Cell-free Methylation Markers

Taiwan
Geneplus-Beijing Co. Ltd.
Beijing Hospital; Emergency General Hospital

Recruiting

Benign/Malignant Pulmonary Nodule Classification Based on High-throughput Whole-genome Methylation Sequencing(GM-seq)

Pulmonary Nodule, Solitary | Whole-genome Methylation Sequencing

China
Novartis

Completed

Evaluation of HIV-1, HCV and HBV Blood Screening Tests With Human Blood Donor Specimens

Screening for the Presence of HIV-1, RNA and HBV DNA in Blood Donations

Taiwan
Bispebjerg Hospital
Sygehus Lillebaelt

Active, not recruiting

Quantification of DNA Repair Products in the Urine After Ultraviolet Radiation of the Skin

DNA Damage | Ultraviolet Rays; Injury | DNA Adduct Formation | DNA Damage, Radiation Induced

Denmark
National Research Centre for the Working Environment...
Rigshospitalet, Denmark; University of Copenhagen; University Hospital Bispebjerg...

Recruiting

Effect on Markers of Cardiovascular, Reproductive and Cancer Risk From Firefighting Training (BIOBRAND3)

Oxidative Stress | Heart Rate Variability | Heat Stress | Reactive Hyperemia | Micro RNA | DNA Strand Breaks

Denmark
National Center for Tumor Diseases, Heidelberg
AstraZeneca; German Cancer Research Center; PharmaMar

Completed

Study of Olaparib/Trabectedin vs. Doctor's Choice in Solid Tumors (NCT-PMO-1603)

Cancers With DNA Repair-Deficiency

Germany
University of Zagreb
University of Split, School of Medicine

Recruiting

Assessment of the Cytotoxic and Genotoxic Effect of Toothpastes With Different Forms of Fluoride on the Buccal Mucosa

DNA Damage

Croatia
University of Split, School of Medicine

Recruiting

In Vivo Assessment of Geno- and Cytotoxicity of Fluoridated Toothpastes and Mouthrinses on Buccal Epithelial Cells

DNA Damage

Croatia
Reproductive Medicine Associates of New Jersey

Completed

Validation of the Accuracy of DNA Fingerprinting Using Polar Bodies and Embryonic Cells

DNA Fingerprinting

United States
University Hospital, Geneva
Prof Laurent Kaiser; Dr Samuel Cordey; Dr Stavroula Masouridi-Levrat; Prof Christian... and other collaborators

Completed

DNA and RNA Viruses of the Blood Virome of Allogeneic Hematopoietic Stem Cell Transplant Recipients (GeBVir)

RNA Virus Infections | DNA Virus Infections | Hematopietic Stem Cell Transplantation | Blood Virome

Switzerland
Tahitian Noni International, Inc.
University of Illinois at Chicago

Completed

Effect of Noni Juice on Lipid Peroxidation-derived DNA Adducts in Heavy Smokers

DNA Damage

United States
University Hospital, Essen

Not yet recruiting

Optimization of Radiation Protection Through Genomic Analyses (ORtogether)

Cancer | Radiation | DNA

Germany
Benha University
Hawaa Fertility Center

Terminated

Effect of Different Sperm Processing Methods in ICSI Outcome.

Sperm DNA Fragmentation

Egypt

Clinical Trials on DNA Methylation

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Zimbabwe

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations