Clinical Trials on DNA-virusinfecties

Total 23145 results

Khondrion BV

Not yet recruiting

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases (KH176-301)

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)
Children's Hospital Medical Center, Cincinnati

Recruiting

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

Lymphoma | Follicular Lymphoma | Leukemia | B Cell Lymphoma | Hodgkin Lymphoma | Burkitt Lymphoma | AML | Non Hodgkin Lymphoma | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Diffuse Large B Cell Lymphoma | Hematologic Malignancy | Chronic Myelogenous Leukemia | Myeloproliferative Neoplasm | T-cell Lymphoma | Peripheral T Cell Lymphoma and other conditions

United States
University of Sao Paulo General Hospital
GlaxoSmithKline

Recruiting

Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases (RZVRheum)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Systemic Sclerosis | Juvenile Idiopathic Arthritis | Sjogren's Syndrome | Spondylitis, Ankylosing | Spondyloarthritis | Behçet Disease | Idiopathic Inflammatory Myopathies | Vasculitis, Systemic | Dermatomyositis, Juvenile

Brazil
Philogen S.p.A.

Recruiting

L19IL2/L19TNF in Skin Cancer Patients (IntriNSiC)

Kaposi Sarcoma | Merkel Cell Carcinoma | BCC - Basal Cell Carcinoma | SCC - Squamous Cell Carcinoma | Keratoacanthoma of Skin | Malignant Adnexal Tumors of the Skin (MATS) | Tumors From Cutaneous T-cell Lymphoma (CTCL)

Spain, France, Italy
Ocellaris Pharma, Inc.

Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers

Sarcoma | Neoplasms | Renal Cell Carcinoma | Cervical Cancer | Cancer | Hepatocellular Carcinoma | Gastric Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Squamous Cell Carcinoma of Head and Neck | Bladder Cancer | Triple Negative Breast Cancer | Urothelial Carcinoma | Merkel Cell Carcinoma | Squamous... and other conditions

Canada
St. Jude Children's Research Hospital
Baylor College of Medicine; Children's Hospital of Philadelphia; Dana-Farber... and other collaborators

Recruiting

Investigation of the Genetics of Hematologic Diseases

Myelodysplastic Syndromes | Sickle Cell Disease | Fanconi Anemia | Severe Congenital Neutropenia | Bone Marrow Failure Syndromes | Blood Coagulation Disorder | Erythrocyte Disorder | Leukocyte Disorder | Hemostasis | Dyskeratosis Congenita | Diamond-Blackfan Anemia | Congenital Thrombocytopenia | Myeloproliferative...

United States
Arcus Biosciences, Inc.

Completed

A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies

Melanoma | Renal Cell Carcinoma | Breast Cancer | Colorectal Cancer | Ovarian Cancer | Squamous Cell Carcinoma of the Head and Neck | Bladder Cancer | Endometrial Cancer | Non-small Cell Lung Cancer | Castration-resistant Prostate Cancer | Merkel Cell Carcinoma | GastroEsophageal Cancer

United States, Australia
Khondrion BV
Julius Clinical; ProPharma Group; Certara

Completed

The KHENEREXT Study

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) | Chronic Progressive External Ophthalmoplegia (CPEO)

Netherlands, Denmark, United Kingdom, Germany
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members

Fatigue | Overweight | Lynch Syndrome | Chronic Lymphocytic Leukemia | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Breast Carcinoma | Cancer Survivor | Ovarian Carcinoma | Health Status Unknown | Body Mass Index 25 or Greater

United States
VelosBio Inc., a subsidiary of Merck & Co., Inc...

Completed

A Study of Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Hematologic Malignancies (MK-2140-001)

Follicular Lymphoma | Acute Myeloid Leukemia | Burkitt Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Diffuse Large B-cell Lymphoma | Acute Lymphoid Leukemia | Richter Transformation Lymphoma | Lymphoplasmacytoid Lymphoma | T-cell Non-Hodgkin...

United States
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Stem Cell Transplantation (SCT) for Genetic Diseases

Thrombocytopenia | Inborn Errors of Metabolism | Metachromatic Leukodystrophy | Fanconi's Anemia | Thalassemia Major | Pure Red-Cell Aplasia

United States
Hospital General Universitario Gregorio Marañon
Instituto de Salud Carlos III

Recruiting

Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Control the Immune Hyperactivation Associated With COVID-19 and/or Acute Respiratory Distress Syndrome (THYTECH2) (THYTECH2)

Systemic Inflammatory Response Syndrome

Spain
Fundacin Biomedica Galicia Sur
University of Vigo; Galician South Health Research Institute

Not yet recruiting

Differential Diagnosis of Persistent COVID-19 by Artificial Intelligence (DICOPERIA)

COVID-19 | Fatigue | Cognitive Dysfunction | COVID-19 Recurrent | SARS CoV 2 Infection | Distress Respiratory Syndrome

Spain
Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Recruiting

Effect of Slope Time in PCV Mode on Mechanical Power Calculation and Oxygenation in Covid-19 ARDS Patients.

COVID-19 Pneumonia | COVID-19 Acute Respiratory Distress Syndrome

Turkey
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV (ACT2)

Cervical Cancer | Human Immunodeficiency Virus | Human Papillomavirus | CIN2 | CIN3

South Africa
Andrei Carvalho Sposito

Not yet recruiting

Clinical Trial of Efficacy and Safety of Oral Drug in Adult Patients With COVID-19 (WP1122)

COVID-19 | Mechanical Ventilation Complication | COVID-19 Acute Respiratory Distress Syndrome

Brazil
The University of Hong Kong

Recruiting

The Long-term Spill-over Impact of COVID-19 on Health and Healthcare of People With Non-communicable Diseases

Cardiovascular Diseases | Hypertension | Diabetes Mellitus | Cancer | Kidney Disease, Chronic | Noncommunicable Diseases | Chronic Respiratory Disease

China
University of British Columbia
Centers for Disease Control and Prevention

Recruiting

Genomics and COVID-19 Vaccine Adverse Events

Vaccine Adverse Reaction

Canada
Assistance Publique - Hôpitaux de Paris
National Research Agency, France

Recruiting

Characterization of the microVAScular Dysfunction in Covid-19 ARDS (VASCOV)

ARDS, Human | COVID-19 Acute Respiratory Distress Syndrome

France
Cambridge Health Alliance
The Thoracic Foundation; Alturix

Not yet recruiting

NAC for Attenuation of COVID-19 Symptomatology (NACinCOVID2)

Covid19 | Oxidative Stress | SARS-CoV2 Infection | COVID-19 Pneumonia | SARS-CoV-2 Acute Respiratory Disease | COVID-19 Respiratory Infection | SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere | COVID-19 Lower Respiratory Infection

United States
GeoVax, Inc.
National Cancer Institute (NCI)

Recruiting

SARS-CoV-2 Vaccine (GEO-CM04S1) Versus mRNA SARS-COV-2 Vaccine in Patients With Blood Cancer

Lymphoma | Leukemia | Plasma Cell Myeloma | Hematopoietic and Lymphoid System Neoplasm | COVID-19 Infection

United States
University of Athens

Recruiting

Cerebral Autoregulation and COVID-19 (CA-COVID)

COVID-19 Pneumonia | COVID-19 Acute Respiratory Distress Syndrome

Greece
Assiut University

Not yet recruiting

Comparison for the Effect of Neuromuscular Blocking Agents Versus Sedation Alone on Severe ARDS Patients Due to COVID-19

ICU Acquired Weakness | Sedation Complication | COVID-19 Acute Respiratory Distress Syndrome
University of Novi Sad
Merck Sharp & Dohme LLC

Recruiting

Neuroinflammation and Neurodegeneration in HIV-positive Subjects Switched and Initially Treated With INSTI

Metabolic Syndrome | Aging | HIV I Infection | HIV Associated Lipodystrophy

Serbia
Ciusss de L'Est de l'Île de Montréal

Not yet recruiting

Pilot Study for Cyproheptadine in Hospitalized Patient for COVID-19

COVID-19 Pneumonia | Serotonin Syndrome | Platelet Dysfunction | Viral Pneumonia
AVEM HealthCare

Not yet recruiting

The Use of Exosomes for the Treatment of Acute Respiratory Distress Syndrome or Novel Coronavirus Pneumonia Caused by COVID-19 (ARDOXSO)

Covid19 | Acute Respiratory Distress Syndrome | Novel Coronavirus Pneumonia

United States
Ministry of Health, Brazil
InCor Heart Institute

Recruiting

Prevention of Acute Myocardial Injury by Trimetazidine in Patients Hospitalized for COVID-19 (PREMIER)

Myocardial Injury | Covid19 | Acute Respiratory Distress Syndrome

Brazil
University of Cologne

Recruiting

Hantavirus Registry - HantaReg (HantaReg)

Hantavirus Infections | Hemorrhagic Fever With Renal Syndrome | Nephropathia Epidemica | Hantavirus Cardiopulmonary Syndrome

Germany
Massachusetts General Hospital
Baylor College of Medicine; University of Houston; University of Texas at Austin and other collaborators

Recruiting

Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV

Depression | Smoking | Smoking Cessation | Anxiety | Nicotine Dependence | Human Immunodeficiency Virus | Smoking, Cigarette

United States
Centre Hospitalier Henri Duffaut - Avignon

Terminated

Interleukine 6 (IL6) Assay for Predicting Failure of Spontaneous Breathing in Patients With COVID-19 Acute Respiratory Distress Syndrome

COVID-19 Acute Respiratory Distress Syndrome

France
M.D. Anderson Cancer Center

Active, not recruiting

Distress Associated With Coronavirus Disease 2019 and Telehealth on Supportive Care Patients With Advanced Cancer

Hematopoietic and Lymphoid Cell Neoplasm | Advanced Malignant Solid Neoplasm | Locally Advanced Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | COVID-19 Infection | Recurrent Hematologic Malignancy

United States
University Medical Center Groningen

Completed

RECOVAC - Long Term Efficacy and Safety of COVID-19 (SARS-CoV-2) Vaccination in Kidney Disease Patients (LESS CoV-2)

Covid19 | Chronic Kidney Diseases | SARS-CoV Infection

Netherlands
Icahn School of Medicine at Mount Sinai

Active, not recruiting

VNS for Long-COVID-19

Postural Tachycardia Syndrome | Post-COVID-19 Syndrome | Dysautonomia

United States
Laval University
Canadian Institutes of Health Research (CIHR)

Completed

Physical and Cognitive Impairments in People Suffering From Long COVID

COVID-19 | Quality of Life | Cognitive Impairment | Cognitive Dysfunction | Corona Virus Infection | Physical Disability | SARS-CoV-2 Infection | Impairment | Symptoms and Signs

Canada
Karolinska Institutet
Karolinska University Hospital

Active, not recruiting

Physical Training in Patients With POTS After Covid-19 (POTS-ReCOV)

Covid19 | Postural Orthostatic Tachycardia Syndrome | Post-acute Covid-19 Syndrome

Sweden
Centre Hospitalier Universitaire de Nice

Completed

Prone Positioning and R/I Ratio in COVID-19 Patients With ARDS (SyDRAC-DV) (SyDRAC-DV)

COVID-19 Acute Respiratory Distress Syndrome

France
Chinese University of Hong Kong

Completed

Safety and Clinical and Virologic Outcomes in CKD Patients Treated With Nirmatrelvir-ritonavir

COVID-19 | Chronic Kidney Disease stage4 | Chronc Kidney Disease Stage 5

Hong Kong
April M Young
National Institute on Drug Abuse (NIDA); Emory University; Centers for Disease... and other collaborators

Completed

Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)

HIV Infections | Substance Use | Opioid Use | HCV Infection | Sexually Transmitted Infections (Not HIV or Hepatitis) | Overdose, Drug

United States
Ankara City Hospital Bilkent
Baskent University

Completed

Early Versus Delayed Enteral Nutrition in Critically Ill Adults With COVID-19

Enteral Nutrition | COVID-19 Acute Respiratory Distress Syndrome

Turkey
Tonix Pharmaceuticals, Inc.

Completed

A Phase 2 Study to Evaluate the Efficacy and Safety of TNX-102 SL in Patients With Multi-Site Pain Associated With Post-Acute Sequelae of SARS-CoV-2 Infection (PREVAIL)

COVID-19 | Long COVID | Post-Acute Sequelae of SARS-CoV-2 (PASC) Infection | Long Haul COVID

United States
Aveni Foundation

Withdrawn

CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19 (CORONA)

COVID-19 | Acute Respiratory Distress Syndrome | Cytokine Storm
Karolinska Institutet
Karolinska University Hospital

Enrolling by invitation

Effects of Individual Tailored Physical Exercise in Patients With POTS After COVID-19 - a Randomized Controlled Study

COVID-19 | Postural Orthostatic Tachycardia Syndrome | Post COVID-19 Condition | Post-Acute COVID-19 Syndrome

Sweden
SÜMEYYE BİLGİLİ
Ataturk University

Completed

The Effect of Listening to Music During CPAP on the Agitation Levels and Compliance.

COVID-19 | COVID-19 Acute Respiratory Distress Syndrome

Turkey
The University of Texas Health Science Center,...
United States Department of Defense; Akebia Therapeutics Inc.

Completed

Vadadustat for the Prevention and Treatment of Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19)

Coronavirus Infection | Acute Respiratory Distress Syndrome

United States
Banc de Sang i Teixits

Completed

Efficacy and Safety Evaluation of Mesenchymal Stem Cells for the Treatment of Patients With Respiratory Distress Due to COVID-19 (COVIDMES)

COVID-19 | SARS-CoV 2 | Adult Respiratory Distress Syndrome

Spain
Central Hospital, Nancy, France

Completed

Comparison of ARDS COVID-19 (WHO) vs ARDS Influenza in the ICU

Influenza | ARDS | COVID-19 Acute Respiratory Distress Syndrome

France
University of Minnesota
Bill and Melinda Gates Foundation

Completed

Losartan for Patients With COVID-19 Requiring Hospitalization

Acute Respiratory Distress Syndrome | Corona Virus Infection | SARS-CoV Infection

United States
Alexion Pharmaceuticals

Terminated

Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe Pneumonia

Pneumonia, Viral | Acute Respiratory Distress Syndrome | Acute Lung Injury | COVID-19 Severe Pneumonia

United States, Spain, United Kingdom, France, Japan
Sanofi Pasteur, a Sanofi Company

Completed

Regulatory Post-Marketing Surveillance Study for TETRAXIM™

Pertussis | Tetanus | Diphtheria | Poliomyelitis

Korea, Republic of
Uppsala University
Karolinska University Hospital; Sahlgrenska University Hospital, Sweden; University... and other collaborators

Completed

Impact of COVID-19 After Autologous Hematopoietic Stem Cell Transplantation in Sweden (AutoCOVID-19)

Covid19 | Hematologic Neoplasms | Stem Cell Transplant Complications | Myeloma Multiple | Malignant Lymphoma

Sweden

Clinical Trials on DNA-virusinfecties

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