Clinical Trials on De Novo Transplant Disease in Germany

Total 58 results

Erasmus Medical Center
Hoffmann-La Roche

Completed

Fixed Dose MMF vs Concentration Controlled MMF After Renal Transplantation

De Novo Renal Transplant Recipient.

France, Spain, Taiwan, Denmark, Australia, United Kingdom, Germany, Canada, Belgium, China, Sweden, Netherlands, Austria, Brazil, Estonia, Lithuania, Norway, Poland, Venezuela
Novartis

Completed

Pharmacokinetic Study of AEB071 in Patients Following Liver Transplantation

de Novo Liver Transplantation

Germany, Italy, Switzerland
Biotronik AG

Completed

First in Man Trial - BIOSOLVE-I (BIOSOLVE-I)

de Novo Lesions in Native Coronary Arteries

Netherlands, Switzerland, Germany, Belgium
Astellas Pharma Inc

Completed

A Study to Assess the Efficacy and Safety of Alefacept in Kidney Transplant Recipients

De Novo Kidney Transplantation

Belgium, France, Netherlands, Spain, Sweden, Austria, Italy, Germany, United Kingdom, Hungary, Poland, Czech Republic
Novartis Pharmaceuticals

Completed

Comparison of a Tacrolimus Hexal® Based Regimen Versus a Prograf® Based Regimen in de Novo Renal Transplant Recipients (Spartacus)

Pharmacokinetics Study in de Novo Kidney Transplantation

Germany
Biotronik AG

Completed

Long Term Safety Profile of the PRO-Kinetic ENERGY Coronary Stent System in Daily Clinical Practice (ENERGY)

De Novo and Re-stenosed Coronary Artery Lesions

Switzerland, Netherlands, Israel, Spain, Latvia, Germany, Austria, Belgium, France, Ireland
University Hospital, Saarland

Terminated

Efficacy of the SeQuent®Please in the Treatment of De-novo Stenoses Versus Taxus™Liberté™ (PEPCAD-DEBonly)

Coronary De-novo Stenoses

Germany
Gesellschaft fur Medizinische Innovation - Hamatologie...

Recruiting

National Acute Promyelocytic Leukemia (APL) Observational Study NAPOLEON-Registry of the German AML Intergroup

Newly-diagnosed APL (de Novo or Therapy-related) | Relapsed APL

Germany
Hannover Medical School
University Hospital, Ghent; Johann Wolfgang Goethe University Hospital; University... and other collaborators

Unknown

Treatment of Adults Aged Up to 60 Years With De Novo Acute Myeloblastic Leukaemia,Secondary AML, or RAEB-T

De Novo Akute Myeloid Leukemia (AML) | Secondary Acute Myeloid Leukemia (AML) | Refractory Anemia With Excess of Blasts in Transformation

Germany
Technical University of Munich
Hannover Medical School; University Hospital Heidelberg; Klinikum der Universität... and other collaborators

Recruiting

The Transplant Cohort of the German Center for Infection Research

Infections | Immunosuppression | Transplant Failure | Transplant Complication

Germany
Heidelberg University

Unknown

Multicenter CTS Pre-and Post-Transplantation Covid-19 Serum Studies

Covid19 | Liver Transplant; Complications | Kidney Transplant; Complications | Kidney Transplant Failure and Rejection | Liver Transplant Failure and Rejection

Germany
ExThera Medical Europe BV
University Hospital, Essen

Not yet recruiting

Reduction of BK Viremia in Kidney Transplant Patients (CP026)

Kidney Diseases | Kidney Transplant Infection | Kidney Transplant; Complications

Germany
Hansa Biopharma AB

Terminated

An Long-term Follow-up Trial of Kidney Tx Patients Treated With Imlifidase or PE After an AMR

Kidney Transplant Rejection

Germany, France, Austria
LMU Klinikum

Completed

Impact of Level and Quality of Immunosuppression on Onset and Pattern of Cardiac Allograft Vasculopathy Evaluated by OCT (IMPROVE-OCT)

Transplant; Failure, Heart

Germany
Hannover Medical School

Completed

Diagnosis of Acute Rejection in Renal Transplant Patients by Urine Mass Spectrometry

Rejection of Renal Transplant

Germany
Martin-Luther-Universität Halle-Wittenberg

Completed

SPRINT Trial Type Blood Pressure Measurements in Patients After Kidney Transplantation

Arterial Hypertension | Kidney Transplant; Complications

Germany
HepNet Study House, German Liverfoundation

Completed

Seasonal Flu Vaccine in Adult Transplant Recipients (Fluad Tx)

Immunocompromised | Transplanted

Germany
Max Planck Institute for Human Cognitive and Brain...
Hannover Medical School; Leipzig University Medical Center

Completed

Investigations of the Pathophysiology of Gilles de la Tourette Syndrome. Part 1: Simultaneous PET and 3T MRI

Tourette Syndrome | Gilles de la Tourette Syndrome

Germany
University of Giessen

Completed

Immunosuppressive Regimen on Changes in Renal Function and Transplant Rejection Rate in Patients With Lung Transplant

Chronic Kidney Diseases | Lung Transplant; Complications

Germany
Max Planck Institute for Human Cognitive and Brain...
Hannover Medical School; Leipzig University Medical Center

Completed

Investigations of the Pathophysiology of Gilles de la Tourette Syndrome. Part 2: 7T MRI

Tourette Syndrome | Gilles de la Tourette Syndrome

Germany
University of Giessen
Novartis; Hoffmann-La Roche; Astellas Pharma Inc; Heidelberg University

Completed

Impact of Immunosuppressive Regimens on Polyomavirus-related Transplant Nephropathy

Polyomavirus Infections

Germany
Charite University, Berlin, Germany

Recruiting

Hypothermic Oxygenated (HOPE) Versus Normothermic Machine Perfusion (NMP) in Human Liver Transplantation (HOPE-NMP)

Liver Transplant Disorder | Hepatocellular Injury

Germany
Novartis Pharmaceuticals

Terminated

Efficacy and Safety of LFG316 in Transplant Associated Microangiopathy (TAM) Patients

Transplant Associated Microangiopathy TAM

France, United States, Germany
CTI BioPharma

Completed

Comparison of Pixantrone + Rituximab With Gemcitabine + Rituximab in Patients With Aggressive B-cell Non-Hodgkin Lymphoma or Follicular Grade 3 Lymphoma Who Have Relapsed After Therapy and Are Not Eligible for Stem Cell Transplant (PIX-R)

Diffuse Large B-cell Lymphoma | de Novo DLBCL | DLBCL Transformed From Indolent Lymphoma | Follicular Grade 3 Lymphoma

United States, Germany, Italy, United Kingdom, Hungary, France, Spain, Ukraine, Czechia, Austria, Belgium, Bulgaria, Denmark, Poland, Romania, Russian Federation, Slovakia
Universitätsklinikum Hamburg-Eppendorf
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Recruiting

The PAtients pResenTing With COngenital HeaRt DIseAse Register (ARTORIA-R) (ARTORIA-R)

Heart Failure | Ventricular Dysfunction | Congenital Heart Disease | Arrythmia | Transplant; Complication, Failure

Germany
University of Cologne

Unknown

Changes in the Gut Microbiota of Patients Undergoing Allogeneic Stem Cell Transplantation (COLLECT) (COLLECT)

Acute Myeloid Leukemia | Allogeneic Hematopoietic Stem Cell Transplantation | Stem Cell Transplant Complications | Graft-versus-host-disease

Germany
Lux Biosciences, Inc.

Terminated

Study to Assess the Efficacy and Safety of LX201 for Prevention of Corneal Allograft Rejection Episodes and Graft Failure in Subjects at Increased Immunological Risk

Corneal Diseases | Cornea Transplant

United States, Germany
Zambon SpA

Active, not recruiting

Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-1) (BOSTON-1)

Bronchiolitis Obliterans | Lung Transplant Rejection | Lung Transplant; Complications | Lung Transplant Failure and Rejection | Chronic Rejection of Lung Transplant | Chronic Lung Allograft Dysfunction

France, United States, Spain, Israel, Belgium, United Kingdom, Germany
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Clinical Cohort Study - TRUST (TRUST)

Atrial Fibrillation | Arrhythmias, Cardiac | Ventricular Tachycardia | Atrial Flutter | Supraventricular Tachycardia | Brugada Syndrome | Atrial Tachycardia | Torsades de Pointes | Long QT Syndrome | Arrhythmogenic Right Ventricular Dysplasia | Catecholaminergic Polymorphic Ventricular Tachycardia | Atrial Cardiomyopathy

Germany
Zambon SpA

Active, not recruiting

Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-2) (BOSTON-2)

Bronchiolitis Obliterans | Lung Transplant Rejection | Lung Transplant; Complications | Lung Transplant Failure and Rejection | Chronic Rejection of Lung Transplant | Chronic Lung Allograft Dysfunction

France, United States, Spain, Israel, Belgium, Denmark, Germany, United Kingdom, Austria
TransMedics

Completed

International EXPAND Lung Pivotal Trial (EXPANDLung)

Lung Transplant

United States, Belgium, Germany, Spain
Charite University, Berlin, Germany

Recruiting

Normothermic Machine Perfusion (NMP) Versus Static Cold Storage (SCS) in Human Kidney Transplantation (NMP-DBD)

Kidney Failure | Kidney Transplant; Complications | Graft Dysfunction

Germany
University of Erlangen-Nürnberg Medical School

Terminated

The Influence of TaKeTiNa Music Therapy, Traditional Chinese Acupuncture and Clown Theatrical Performance on Quality of Life and the Therapeutic Process of Patients Undergoing Allogenic Stem Cell Transplantation (TriCAM)

Depression | Quality of Life | Leukemia | Graft-Versus-Host Disease | Stem Cell Transplant Complications | Hematological Neoplasm

Germany
Diako Ev. Diakonie-Krankenhaus gemeinnützige GmbH

Completed

Risk-stratified Sequential Treatment of Post-transplant Lymphoproliferative Disease (PTLD) With Rituximab SC and Immunochemotherapy (PTLD-2)

Posttransplant Lymphoproliferative Disorder

Germany
University Hospital, Aachen

Completed

HOPE for Human Extended Criteria and Donation After Brain Death Donor (ECD-DBD) Liver Allografts (HOPE-ECD-DBD)

Liver Transplant | Hepatocellular Injury

Germany, Czechia
Predict4Health

Active, not recruiting

Clinical Impact of the iBox as an Early Intervention tooL (CIBIL)

Kidney Diseases | Kidney Failure, Chronic | Kidney Transplant Rejection | Kidney Disease, Chronic | Kidney Failure | Kidney Transplant; Complications | Kidney Dysfunction

Spain, United Kingdom, Austria, France, Germany, Israel
University of Erlangen-Nürnberg Medical School

Recruiting

Proteinuria and Renal Perfusion in Renal Transplant Recipients

End Stage Renal Disease | Living Donor Kidney Transplantation | Renal Perfusion | Pre-kidney Transplant

Germany
Heinrich-Heine University, Duesseldorf

Recruiting

Vaccination Against COVID-19 in Chronic Kidney Disease

Vaccine Response Impaired | Chronic Kidney Disease Stage 5 on Dialysis | Chronic Kidney Disease Stage 5 With Transplant

Germany
Azienda Socio Sanitaria Territoriale degli Spedali...

Recruiting

The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study (V-CHECK)

Corneal Endothelial Cell Loss | Corneal Transplant Failure

Spain, Germany, Netherlands, Belgium, Italy, United Kingdom
iOMEDICO AG

Active, not recruiting

Non-interventional Study to Evaluate Patient and Healthcare Provider Satisfaction of Daratumumab Use in the Treatment of First-line Daratumumab, Lenalidomide, Dexamethasone (DRd) Multiple Myeloma Patients in Germany Depending on Application Route (sc or iv) (MYLENE)

Multiple Myeloma | Patient Satisfaction | Personal Satisfaction | Newly Diagnosed | Transplant Ineligible | Patient Preference

Germany
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of Everolimus in Combination With Reduced Exposure Cyclosporine or Tacrolimus in Paediatric Liver Transplant Recipients.

Renal Function | Liver Transplant

United States, Germany, Spain, Belgium, France, Hungary, Australia, Sweden, Italy, Canada, United Kingdom, Denmark
Novartis Pharmaceuticals

Completed

Efficacy, Tolerability and Safety of Early Introduction of Everolimus, Reduced Calcineurin Inhibitors and Early Steroid Elimination Compared to Standard CNI, Mycophenolate Mofetil and Steroid Regimen in Paediatric Renal Transplant Recipients

Prevention of Acute Rejection in Paediatric Recipients of a Renal Transplant

Germany, United Kingdom, France, Italy, United States, Hungary, Norway, Spain, Argentina, Brazil, Poland, Sweden, Turkey
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Low-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia

Recurrent Adult Acute Myeloid Leukemia | Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult... and other conditions

United States, Germany
Clinuvel Pharmaceuticals Limited

Unknown

Phase II AK Study in Organ Transplant Patients

Carcinoma, Squamous Cell | Actinic Keratoses | Organ Transplant Recipients

Australia, Sweden, Switzerland, Italy, France, Belgium, Germany
Zambon SpA

Terminated

A Safety Study of Liposomal Cyclosporine A to Treat Bronchiolitis After Hematopoietic Transplant (BOSTON-4) (BOSTON-4)

Stem Cell Transplant Complications | GVHD, Chronic | Bronchiolitis Obliterans Syndrome (BOS)

Spain, France, Germany
Tuberculosis Network European Trialsgroup

Unknown

New Generation IGRA in Immunocompromised Individuals (TBnet#54)

Active Tuberculosis | Monitoring, Immunologic | Tuberculosis in Solid Organ Transplant Recipients | Tuberculosis in Marrow Transplant Recipients | Tuberculosis in Rheumatoid Arthritis | Tuberculosis in Chronic Renal Failure | Tuberculosis in HIV-infected Individuals

Denmark, Germany, Italy, Moldova, Republic of, Norway, Poland, Portugal, Romania, Spain, United Kingdom
Prof. Tobias Feuchtinger
European Commission; Simbec-Orion Group Ltd, Merthyr Tydfil, UK; Miltenyi Biotec... and other collaborators

Recruiting

Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections (TRACE)

CMV Infection | EBV Infection | Stem Cell Transplant Complications | AdV Infection

Belgium, Spain, France, Germany, Italy, Netherlands
Astellas Pharma Global Development, Inc.

Completed

A Study to Evaluate a Therapeutic Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seropositive Recipients Undergoing Allogeneic, Hematopoietic Cell Transplant (HCT) (HELIOS)

Cytomegalovirus (CMV)-Positive Recipients | Allogeneic, Hematopoietic Cell Transplant (HCT)

Japan, Korea, Republic of, United States, Canada, Australia, Belgium, France, Germany, Spain, Sweden, Taiwan
Gilead Sciences

Completed

Safety and Efficacy of Sofosbuvir and Ribavirin in Adults With Recurrent Chronic Hepatitis C Virus (HCV) Post Liver Transplant

Post Liver Transplant | Recurrent Chronic Hepatitis C Virus

United States, Spain, New Zealand, France, Germany
Incyte Corporation

Active, not recruiting

A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib

Chronic Graft Versus Host Disease | Myelofibrosis | Postlung Transplant (Bronchiolitis Obliterans)

United States, Spain, Italy, Germany, Belgium, Austria, Israel, Canada, Greece

Clinical Trials on De Novo Transplant Disease in Germany

Sponsors and Collaborators

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CROs in Montenegro

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