Clinical Trials on De Lange Syndrome

Total 35721 results

National Heart, Lung, and Blood Institute (NHLBI)

Completed

Safety of ON 01910.Na in Patients With Myelodysplasia

Myelodysplastic Syndrome (MDS)

United States
Telik

Terminated

Study of (Telintra®) in Non-Del(5q) Myelodysplastic Syndrome

Myelodysplastic Syndrome (MDS)

United States
Oncology Specialties, Alabama

Terminated

Phase II Research Study of Arsenic Trioxide (Trisenox) in Patients With Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome (MDS)

United States
Università degli Studi di Ferrara
B. Braun Melsungen AG

Completed

Effects of Different Strategy of Fluids Administration on Acid/Base Disorders and Inflammatory Mediators

Large Bowel Cancer

Italy
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Not yet recruiting

Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas

Hodgkin Lymphoma | Non-Hodgkin Lymphoma | Peripheral T-cell Lymphoma | Anaplastic Large Cell Lymphoma, ALK-Positive | Anaplastic Large Cell Lymphoma, ALK-negative | CD30-Positive Diffuse Large B-Cell Lymphoma | Anaplastic Large Cell Lymphoma, T Cell and Null Cell Type

United States
National Cancer Institute (NCI)

Terminated

Decitabine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) | Secondary Acute Myeloid Leukemia and other conditions

Canada
Thomas Jefferson University
AbbVie

Recruiting

Evaluating Navitoclax After Failure of Standard Treatments of Azacitidine or Decitabine and Venetoclax in Patients With Aggressive Myelodysplastic Syndrome

Myelodysplastic Syndrome | Recurrent Myelodysplastic Syndrome | Refractory Myelodysplastic Syndrome

United States
Scripps Health
J. Craig Venter Institute

Completed

Biomarker Monitoring in TP53 Mutation Carriers

Li-Fraumeni Syndrome | Hereditary Cancer Syndromes | TP53 Gene Germline Mutation Carrier

United States
University of Wisconsin, Madison

Terminated

Botox for the Treatment of Chronic Exertional Compartment Syndrome

Compartment Syndrome of Leg

United States
University of Southern California

Completed

Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery

Ganglion Cysts | Carpal Tunnel Syndrome | Dupuytren Contracture | Trigger Digit | De Quervain Disease

United States
Mayo Clinic

Enrolling by invitation

Effect of Large Language Model in Assisting Discharge Summary Notes Writing for Hospitalized Patients

Large Language Model

United States
Saime Nilay Arman

Completed

KinectROM Application for Assessing Range of Motion in Upper and Lower Extremity: A Development and Validation Study (KinectROM)

Range of Motion

Turkey
Inonu University

Unknown

Length of Small Bowel. How Can Standardise Measurement and Why?

Small/Large Bowel
Takeda

Completed

A Study of Soticlestat as an Add-on Therapy in Children and Young Adults With Dravet Syndrome

Dravet Syndrome (DS)

China, Canada, France, Hungary, Poland, United States, Spain, Greece, Australia, Brazil, Serbia, Germany, Italy, Japan, Latvia, Netherlands, Ukraine, Russian Federation
Erasmus Medical Center

Enrolling by invitation

Long-term Pain Modulation by Intravenous Esketamine in CRPS (KetCRPS-2)

Complex Regional Pain Syndromes | CRPS (Complex Regional Pain Syndromes)

Netherlands
Institut fuer anwendungsorientierte Forschung und...
University Medical Center Goettingen

Completed

Screening and Genetic Monitoring of Patients With Myelodysplastic Syndromes (MDS) Under Different Treatment Modalities by Cytogenetic Analyses of Circulating CD34+Cells

Myelodysplastic Syndromes (MDS) | Chromosmal Aberrations | Karyotype Evolution | Rare Abnormalities | Cytogenetic Monitoring

Germany
Larissa University Hospital

Recruiting

Fat Supplementation on Dumping Syndrome Related Symptoms After Gastric Surgery

Dumping Syndrome | Gastric Surgery

Greece
Children's Hospital of Philadelphia
University of Pennsylvania

Recruiting

Fiber Food Introduction in Pediatric Short Bowel Syndrome

Short Gut Syndrome

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Guadecitabine in Treating Patients With Higher-Risk Myelodysplastic Syndromes

High Risk Myelodysplastic Syndrome

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab and/or Ipilimumab With or Without Azacitidine in Treating Patients With Myelodysplastic Syndrome

Leukemia | Myelodysplastic Syndrome | Recurrent Myelodysplastic Syndrome

United States
Jasper Therapeutics, Inc.

Recruiting

JSP191 (Briquilimab) in Subjects With LR-MDS

Lower-risk Myelodysplastic Syndrome

United States
University Health Network, Toronto
Zogenix, Inc.

Not yet recruiting

Fenfluramine for Adult Dravet Patients

Dravet Syndrome | Dravet Syndrome, Intractable

Canada
University of Texas Southwestern Medical Center
Children's Hospital of Philadelphia

Enrolling by invitation

Predicting Success With Fiber Food Introduction in Short Bowel Syndrome

Short Gut Syndrome

United States
Uma Borate

Recruiting

Venetoclax and Azacitidine for Treatment of Therapy Related or Secondary Myelodysplastic Syndrome

Therapy-Related Myelodysplastic Syndrome | Secondary Myelodysplastic Syndrome

United States
University Hospital, Brest

Recruiting

Haploinsufficiency of the RBM22 and SLU7 Genes in Del(5q) Myelodysplastic Syndromes (SMD-RMB22)

Myelodysplastic Syndromes | Myelodysplastic Syndrome With Isolated Del(5Q) | Myelodysplastic Syndrome With Del(5Q)

France
Cyclacel Pharmaceuticals, Inc.

Suspended

A Study to Investigate Fadraciclib (CYC065), in Subjects With Leukemia or Myelodysplastic Syndrome (MDS)

Leukemia | Myelodysplastic Syndrome(MDS)

United States
Northwestern University

Completed

Atrantil for Intestinal Bacterial Overgrowth

Irritable Bowel Syndrome | SIBO | Bacterial Overgrowth Syndrome

United States
U.S. Army Medical Research and Development Command

Unknown

The Use of Near Infrared Spectroscopy in the Diagnosis of Acute Compartment Syndrome in Trauma Patients (NIRS)

Anterior Tibial Compartment Syndrome

United States
Peter L Greenberg
Amgen

Completed

A Study of Darbepoetin Alfa in Patients With Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes | Myelodysplastic Syndromes (MDS) | Blood Cancer

United States
University Hospital Southampton NHS Foundation...
Hoffmann-La Roche

Terminated

Atezolizumab, Rituximab, Gemcitabine and Oxaliplatin in Patients With Relapsed or Refractory DLBCL Not Suitable for High-dose Therapy (ARGO)

Diffuse Large B Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Relapsed Diffuse Large B-Cell Lymphoma

United Kingdom
University of Washington
National Cancer Institute (NCI)

Withdrawn

Ceritinib With Brentuximab Vedotin in Treating Patients With ALK-Positive Anaplastic Large Cell Lymphoma

Anaplastic Large Cell Lymphoma, ALK-Positive | CD30-Positive Neoplastic Cells Present | Systemic Anaplastic Large Cell Lymphoma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant

Clear Cell Renal Cell Carcinoma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent... and other conditions

United States, Germany, Italy
Korea University Ansan Hospital
B. Braun Korea Co., Ltd.

Recruiting

STabilization of Atheroma By Lipid-reducing Effect of Drug-Coated Balloon (STABLE-DCB) (STABLE-DCB)

Coronary Artery Disease | De Novo Stenosis | Atherosclerotic Plaque

Korea, Republic of
Santa Casa da Misericordia do Rio de Janeiro Hospital

Unknown

Trial of Acupuncture in the Treatment of Fibromyalgia

Fibromyalgia | Myofascial Pain Syndrome, Diffuse | Diffuse Myofascial Pain Syndrome | Fibromyalgia-Fibromyositis Syndrome | Fibromyositis-Fibromyalgia Syndrome

Brazil
National Cancer Institute (NCI)

Completed

Bevacizumab and Cediranib Maleate in Treating Patients With Metastatic or Unresectable Solid Tumor, Lymphoma, Intracranial Glioblastoma, Gliosarcoma or Anaplastic Astrocytoma

Unspecified Childhood Solid Tumor, Protocol Specific | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions

United States
Northwestern University
Bristol-Myers Squibb; National Cancer Institute (NCI); AbbVie

Withdrawn

Venetoclax, Rituximab and Nivolumab in Combination for the Treatment of Richter's Transformation Arising From Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Richter Syndrome | Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma | Transformed Small Lymphocytic Lymphoma to Diffuse Large B-Cell Lymphoma | Recurrent Transformed Chronic Lymphocytic Leukemia | Refractory Transformed Chronic Lymphocytic Leukemia

United States
Major Extremity Trauma Research Consortium

Not yet recruiting

Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)

Acute Compartment Syndrome
Takeda

Recruiting

A Study of Teduglutide (Revestive®) in Participants With Short Bowel Syndrome (SBS) in Canada

Short Bowel Syndrome (SBS)

Canada
GlyPharma Therapeutics
VectivBio AG

Completed

Metabolic Balance Study of FE203799 in Patients With SBS With Intestinal Insufficiency

SBS - Short Bowel Syndrome

Denmark
Groupe Francophone des Myelodysplasies

Completed

Idarubicin Combined to Azacitidine in Int-2 or High Risk Myelodysplastic Syndromes

High Grade Myelodysplastic Syndrome Lesions

France, Tunisia
Maastricht University Medical Center
Myrovlytis Trust

Completed

Topical Rapamycin for Fibrofolliculomas

Birt-Hogg-Dubé Syndrome

Netherlands
Autolus Limited

Completed

CD19/22 CAR T Cells (AUTO3) for the Treatment of Diffuse Large B Cell Lymphoma (ALEXANDER)

Diffuse Large B Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | DLBCL | Relapsed Diffuse Large B-Cell Lymphoma

United States, United Kingdom
Children's Hospital of Fudan University

Not yet recruiting

High-Intensity Interval Training(HIIT) on Cardio-metabolic Risk in School-age Children

Cardiovascular Syndrome, Metabolic
Sinaloa Pediatric Hospital

Completed

Levothyroxine for Children With Euthyroid Sick Syndrome

Euthyroid Sick Syndrome

Mexico
SWOG Cancer Research Network
National Cancer Institute (NCI); Genentech, Inc.

Recruiting

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Grade 3b Follicular Lymphoma | Transformed Follic Lymph to Diff Large B-Cell Lymphoma | Transformed Marg Zone Lymph to Diff...

United States
Hospital for Special Surgery, New York

Recruiting

Forward Looking InfraRed Imaging and Severity Score in Complex Regional Pain Syndrome (FLIR)

CRPS (Complex Regional Pain Syndromes)

United States
Takeda

Recruiting

A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine

Dravet Syndrome (DS) | Lennox-Gastaut Syndrome (LGS)

United Kingdom, Denmark
Takeda

Active, not recruiting

A Study of Soticlestat in Adults and Children With Rare Epilepsies (Endymion 1)

Epilepsy | Dravet Syndrome (DS) | Lennox-Gastaut Syndrome (LGS)

United States, Canada, Australia, China, Israel, Poland, Spain, Portugal
Vern C. Juel, M.D.

No longer available

Treatment Use of 3,4-Diaminopyridine

Myasthenic Syndromes, Congenital

United States
Ricardo Maselli
Catalyst Pharmaceuticals, Inc.

No longer available

Treatment Use of 3,4 Diaminopyridine in Congenital Myasthenia

Congenital Myasthenic Syndrome

United States

Clinical Trials on De Lange Syndrome

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Canada

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations