Clinical Trials on De Lange Syndrome

Total 35802 results

Montefiore Medical Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Interferon Alfa Followed by Filgrastim in Treating Patients With Gastrointestinal Tract Cancer

Gastric Cancer | Pancreatic Cancer | Small Intestine Cancer | Liver Cancer | Extrahepatic Bile Duct Cancer | Gastrointestinal Carcinoid Tumor

United States
Assistance Publique - Hôpitaux de Paris

Completed

Association Corticosteroid/Azathioprine in Microscopic Polyangiitis/ Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome) (CHUSPAN2)

MPA | PAN or EGPA With FFS=0 | At Diagnosis or Within the First 15 Days Following Initiation of Corticosteroids

France
Neuroganics LLC
Ramos Injury Law Firm

Recruiting

National Vaccine Adverse Event Reporting Survey and Etiology (NVAERS)

COVID-19 | Vaccine Adverse Reaction | Vaccine Reaction | Vasculitis | Neuritis | Thrombocytopenia | Influenza | Corona Virus Infection | Blood Clot | Guillain-Barré | Vaccine or Biological Substance, Unspecified Causing Adverse Effects in Therapeutic Use | GWAS | Genetic Sequencing

United States
University Hospital, Strasbourg, France

Recruiting

Cerebro Spinal Fluid Collection (CSF) (Analzheimer)

Alzheimer Disease | Multiple System Atrophy | Frontotemporal Dementia | Dementia With Lewy Bodies | Parkinson's Disease Dementia

France
Novo Nordisk A/S

Completed

Evaluating Acceptance of New Liquid Somatropin Formulation in Children With Growth Hormone Deficiency

Turner Syndrome | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder

Israel
National Taiwan University Hospital
National Cheng-Kung University Hospital

Unknown

Mitochondrial nt3243 A>G Mutation in Taiwan

MELAS Syndrome | Noninsulin-dependent Diabetes Mellitus With Deafness

Taiwan
Children's Hospitals and Clinics of Minnesota
M.D. Anderson Cancer Center; Washington University School of Medicine; Dana-Farber... and other collaborators

Recruiting

International PPB/DICER1 Registry

Neuroblastoma | Thyroid Carcinoma | Pineoblastoma | Wilms Tumor | Embryonal Rhabdomyosarcoma | Ovarian Sarcoma | Sertoli-Leydig Cell Tumor | Pleuropulmonary Blastoma | Gynandroblastoma | DICER1 Syndrome | Cystic Nephroma | Renal Sarcoma | Nodular Hyperplasia of Thyroid | Nasal Chondromesenchymal Hamartoma | Ciliary Body... and other conditions

United States
University of Dublin, Trinity College
Motor Neurone Disease Association, UK; Irish Research Council, IE; Thierry Latran... and other collaborators

Recruiting

Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease

Multiple Sclerosis | Primary Lateral Sclerosis | Postpoliomyelitis Syndrome | Motor Neuron Disease, Amyotrophic Lateral Sclerosis | Motor Neuron Disease Progressive Spinal Muscle Atrophy

Ireland
University of Rochester
University of Colorado, Denver; Massachusetts General Hospital; Stanford University

Recruiting

Community Outreach for Palliative Engagement -- Parkinson Disease (COPE-PD)

Parkinson Disease | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Parkinson's Disease and Parkinsonism | Dementia With Lewy Bodies | Vascular Parkinsonism | Parkinson Disease Dementia | Lewy Body Parkinsonism

United States
NYU Langone Health

Recruiting

Natural History Study of Synucleinopathies

Parkinson Disease | Multiple System Atrophy | Neurogenic Orthostatic Hypotension | REM Sleep Behavior Disorder | Pure Autonomic Failure | Dementia With Lewy Bodies | Patients With Synucleinopathies | Shy-Drager Disease

Korea, Republic of, United States, Argentina, Spain
Reata, a wholly owned subsidiary of Biogen

Completed

Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT

Idiopathic Pulmonary Fibrosis | Pulmonary Arterial Hypertension | Pulmonary Hypertension | Interstitial Lung Disease | Sarcoidosis | Idiopathic Interstitial Pneumonia | Cryptogenic Organizing Pneumonia | Desquamative Interstitial Pneumonia | Respiratory Bronchiolitis Associated Interstitial Lung Disease and other conditions

United States, Germany
Sheba Medical Center

Enrolling by invitation

Brain Network Activation in Patients With Movement Disorders (BNA-MDi)

Parkinson Disease | Cerebellar Ataxia | Dystonia | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Essential Tremor | Dementia With Lewy Bodies | Normal Pressure Hydrocephalus

Israel
University of Pennsylvania

Completed

Cognitive Impairement In Frontotemporal Dementia

Frontotemporal Degeneration | Multiple System Atrophy | Progressive Supranuclear Palsy

United States
Brigham and Women's Hospital
Northeastern University

Completed

Patient Safety Learning Laboratory: Making Acute Care More Patient-Centered (PSLL)

Venous Thromboembolism | Patient Fall | Adverse Drug Event | Severe Hypoglycemia | Hospital Acquired Pressure Ulcer | Central Line-Associated Bloodstream Infection (CLABSI) | Catheter-Associated Infection | Opioid-Related Severe Adverse Drug Event | Severe Hospital Acquired Delerium | Rapid Response Related...

United States
University of Oxford
Wellcome Trust; National Institute for Health Research, United Kingdom; Arthritis...

Completed

Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data

Osteoarthritis | Rotator Cuff Tear | Avascular Necrosis | Inflammatory Arthritis | Shoulder Dislocation | Dupuytren Contracture | Impingement Syndrome, Shoulder | Elbow Arthropathy | Trigger Digit | Shoulder Arthropathy | Upper Limb Nerve Lesion | Wrist Arthropathy | Fracture Elbow | Dislocations | Fracture, Shoulder | Arthropathy... and other conditions
Novo Nordisk A/S

Completed

Norditropin NordiFlex® Device Compared to the Device Previously Used by Patients or Parents

Chronic Kidney Disease | Turner Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Delivery Systems | Foetal Growth Problem | Small for Gestational Age

France
Novo Nordisk A/S

Completed

Usability and Tolerability of the Norditropin NordiFlex® Injection Device in Children Never Previously Treated With Growth Hormone

Chronic Kidney Disease | Turner Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Delivery Systems | Foetal Growth Problem | Small for Gestational Age

France
National Cancer Institute (NCI)

Terminated

Romidepsin in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors

Gastrinoma | Glucagonoma | Insulinoma | Metastatic Gastrointestinal Carcinoid Tumor | Pancreatic Polypeptide Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma | Regional Gastrointestinal Carcinoid Tumor | Pulmonary Carcinoid Tumor

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Unknown

Quality of Life and Care Needs of Patients With Persistent or Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Peritoneal Cancer

Fatigue | Anxiety | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Stage I Ovarian Cancer AJCC v6 and v7 | Stage IA Fallopian Tube Cancer AJCC v6 and v7 | Stage IB Fallopian Tube Cancer AJCC v6 and v7 | Stage IC Fallopian Tube Cancer AJCC... and other conditions

United States
University of Bern
Novartis; University Hospital Inselspital, Berne; Schweizerische Multiple Sklerose... and other collaborators

Recruiting

Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

Multiple Sclerosis | Optic Neuritis | Neuromyelitis Optica Spectrum Disorder | CNS Sarcoidosis | CNS Vasculitis | Transverse Myelitis | Rasmussen Encephalitis | Acute Disseminated Encephalomyelitis | Anti-NMDAR Encephalitis | Anti-GAD65 Associated Autoimmune Encephalitis | Anti-AMPAR-1/2 Associated Autoimmune... and other conditions

Switzerland
Steno Diabetes Center Greenland
Zealand University Hospital; University of Copenhagen

Recruiting

Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland

Diabetes Mellitus, Type 2 | Diabetic Neuropathies | Diabetic Retinopathy | Obstructive Sleep Apnea | Obesity, Morbid | MODY

Greenland
University Hospital, Essen

Recruiting

HIV-HEART Aging Study (HIVH)

Myocardial Infarction | HIV Infections | Heart Failure | Coronary Disease | Aging | Weight Gain | HIV Encephalopathy

Germany
National Cancer Institute (NCI)

Recruiting

Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors

Neuroendocrine Tumors | Von Hippel-Lindau Disease | VHL Pancreatic Neuroendocrine Tumors

United States
ANRS, Emerging Infectious Diseases
University Hospital, Geneva; University of Bordeaux; International Agency for... and other collaborators

Recruiting

Evaluation of Triage Options After HPV Testing for Cervical Cancer Screening Among HIV-infected Women (AIMA-CC)

HIV Infections | HPV - Anogenital Human Papilloma Virus Infection

Burkina Faso, Cambodia, Côte D'Ivoire
The Hospital of Vestfold
Oslo University Hospital

Active, not recruiting

Prevention of Coronary Heart Disease in Morbidly Obese Patients (SphCor)

Hypertension | Obstructive Sleep Apnea | Morbid Obesity | Osteoarthrosis | Type 2 DM

Norway
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204) (RICHI)

Chronic Granulomatous Disease | Hemophagocytic Lymphohistiocytosis | Leukocyte Adhesion Deficiency | Chronic Active Epstein-Barr Virus Infection | HIGM-1 | IPEX

United States, Canada
M.D. Anderson Cancer Center

Completed

Non-Surgical Management of Attenuated and Deleterious (Classical) Familial Adenomatous Polyposis: A Long-term Surveillance Program

Attenuated Familial Adenomatous Polyposis | Deleterious Familial Adenomatous Polyposis

United States
National Cancer Institute (NCI)

Completed

Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer

Familial Adenomatous Polyposis | Attenuated Familial Adenomatous Polyposis

United States, Puerto Rico
Neurogene Inc.

Terminated

A Natural History Study of Charcot-Marie-Tooth 4J (CMT4J) (CMT4J)

Charcot-Marie-Tooth Disease | Hereditary Motor and Sensory Neuropathy IV

United States
University Hospital, Angers

Unknown

Pharmacogenetic Study of Antimitotic Therapies Involved in Hepatic VOD in Children With Nephroblastoma or ALL (MVO)

Acute Lymphoblastic Leukemia | Nephroblastoma | Hepatic Veno-Occlusive Disease

France
Tel-Aviv Sourasky Medical Center

Unknown

Turmeric Supplementation on Polyp Number and Size in Patients With Familial Adenomatous Polyposis.

Familial Adenomatous Polyposis | FAP | FAP Gene Mutation
University Health Network, Toronto
The Leukemia and Lymphoma Society

Completed

Study Evaluating the Tolerance and Biologic Activity of Oral Ciclopirox Olamine in Patients With Relapsed or Refractory Hematologic Malignancy

Acute Myeloid Leukemia | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia | Hematologic Malignancy | Chronic Myelogenous Leukemia | Myelodysplasia | Hodgkin's Disease

Canada
S.L.A. Pharma AG

Completed

Chemoprevention Trial in Familial Adenomatous Polyposis (FAP) Coli Using EPA

FAP | Familial Adenomatous Polyposis Coli

United Kingdom
michal roll

Unknown

Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Polyposis

FAP-Familial Adenomatous Polyposis

Israel
NeurogesX

Terminated

An Open-Label Extension Study of NGX-4010 for the Treatment of Neuropathic Pain

HIV Infections | Pain | Diabetes Mellitus | Diabetic Neuropathies | Peripheral Nervous System Diseases | Neuralgia | Herpes Zoster | Polyneuropathies
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis (coldAPC)

Familial Adenomatous Polyposis | Adenomatous Polyposis Coli | Duodenal Adenoma

Germany
Laurent Servais
SYSNAV

Recruiting

Assessments in Patients With Muscular Pathology and in Control Subjects : The ActiLiège Next Study

Duchenne Muscular Dystrophy | Myotonic Dystrophy 1 | Congenital Muscular Dystrophy | Centronuclear Myopathy | Charcot-Marie-Tooth | Fascioscapulohumeral Muscular Dystrophy

Belgium
Dr. Med Anas Taha
University of Basel; GZO Hospital, Zürich, Switzerland

Recruiting

Development of Machine Learning Models for the Prediction of BMI and Complications After Bariatric Surgery (CABS-Study)

Sleep Apnea, Obstructive | Diabetes Mellitus, Type 2 | Body Weight | Hiatal Hernia | Internal Hernia | GERD | Intussusception | Post-Op Complication | Anastomosis, Leaking | Mesenteric Hernia

Switzerland
Poitiers University Hospital

Recruiting

Prevalence of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) Following Squamous Cell Carcinomas of the Oropharynx Treatment by Combined Chemoradiotherapy (COROSAS)

Oropharyngeal Cancer | Obstructive Sleep Apnea-hypopnea

France
Western Sydney Local Health District

Recruiting

Cold Snare Polypectomy for Duodenal Adenomas in Familial Adenomatous Polyposis (COPDA)

Familial Adenomatous Polyposis

Australia
National Institute of Arthritis and Musculoskeletal...

Recruiting

Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis

Giant Cell Arteritis | Polyarteritis Nodosa | Takayasu's Arteritis | ANCA-Associated Vasculitis | Relapsing Polychondritis

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Using a Targeted Cancer Vaccine (Galinpepimut-S) With Immunotherapy (Nivolumab) in Mesothelioma

Mesothelioma | Wilms Tumor | Pleural Mesothelioma

United States
University of Chicago
Johns Hopkins University; Mayo Clinic; National Institute of Neurological Disorders... and other collaborators

Completed

CASH (Cavernous Angiomas With Symptomatic Hemorrhage) Trial Readiness

Cerebral Cavernous Malformation | Cavernous Angioma | Cavernoma | CCM | Cerebral Cavernous Malformations 1 | Cerebral Cavernous Malformations 2 | Cerebral Cavernous Malformations 3

United States
Lawson Health Research Institute
Alexion Pharmaceuticals, Inc.

Active, not recruiting

Paroxysmal Nocturnal Hemoglobinuria in ESUS & ETUS

Transient Ischemic Attack | Paroxysmal Nocturnal Hemoglobinuria | Cerebral Vein Thrombosis | Embolic Stroke of Undetermined Source

Canada
National Cancer Institute (NCI)

Completed

Nivolumab in Treating Patients With HTLV-Associated T-Cell Leukemia/Lymphoma

Acute Adult T-Cell Leukemia/Lymphoma | Adult T-Cell Leukemia/Lymphoma | Chronic Adult T-Cell Leukemia/Lymphoma | HTLV-1 Infection | Lymphomatous Adult T-Cell Leukemia/Lymphoma | Smoldering Adult T-Cell Leukemia/Lymphoma

United States
Pharvaris Netherlands B.V.

Completed

Dose-ranging Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema (RAPIDe-1)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

Bulgaria, United States, Spain, Israel, Germany, Canada, Czechia, France, Hungary, Italy, Netherlands, Poland, United Kingdom
University of California, San Francisco

Completed

Study of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT)

Sickle Cell Disease | Hemoglobinopathies | Thalassemia | Hematologic Malignancies | Immunodeficiencies | Fanconi's Anemia | Nonmalignant Diseases | Genetic Inborn Errors of Metabolism

United States
University of California, San Francisco
Thrasher Research Fund

Completed

Study of Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT)

Sickle Cell Disease | Hemoglobinopathies | Fanconi Anemia | Thalassemia | Hematologic Malignancies | Immunodeficiencies | Nonmalignant Diseases | Genetic Inborn Errors of Metabolism

United States
Shiphrah Biomedical Inc.
University of South Australia

Terminated

UniSA BackOff! Study: Adelaide PrenaBelt Trial

Pregnancy Complications | Fetal Growth Retardation | Sleep-Disordered Breathing | Infant, Very Low Birth Weight | Stillbirth | Infant, Small for Gestational Age | Fetal Hypoxia | Infant, Low Birth Weight

Australia
Chang Gung Memorial Hospital

Completed

High-flow Nasal Cannula Oxygen Therapy for Ischemic Stroke Patients With Dysphagia and Obstructive Sleep Apnea

Sleep Apnea, Obstructive | Deglutition Disorders | Cerebral Infarction

Taiwan

Clinical Trials on De Lange Syndrome

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uganda

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations