Clinical Trials on Degeneration; Bone in Netherlands

Total 799 results

European Organisation for Research and Treatment...

Withdrawn

Monoclonal Antibody Therapy in Treating Patients With Primary Myelodysplastic Syndrome

Myelodysplastic Syndromes

France, Netherlands, Norway, Belgium, Switzerland, Austria, United Kingdom, Germany, Denmark
Janssen Research & Development, LLC

Terminated

A Study Comparing Siltuximab Plus Best Supportive Care to Placebo Plus Best Supportive Care in Anemic Patients With International Prognostic Scoring System Low- or Intermediate-1-Risk Myelodysplastic Syndrome

Myelodysplastic Syndrome

United States, Belgium, Spain, Australia, Sweden, Netherlands, Russian Federation
Protagonist Therapeutics, Inc.

Recruiting

A Phase 3 Study of Rusfertide in Patients With Polycythemia Vera (VERIFY)

Polycythemia Vera

United States, Hong Kong, Israel, Canada, Spain, Australia, Austria, Germany, United Kingdom, Hungary, Netherlands, Czechia, Portugal, Italy, Poland, France, Belgium, Chile, Turkey, Mexico
AO Clinical Investigation and Publishing Documentation

Terminated

Patients 60 Years and Older Suffering From Mandibular Fractures Registry

Mandibular Fractures

Spain, United States, Netherlands, Sweden, Finland, Taiwan, South Africa, Switzerland, Germany, Malaysia, Mexico, Uruguay, Romania, Serbia, Slovenia
Amgen

Completed

Study To Assess FRacTure Healing With SclerosTin Antibody - Hip (STARTT-Hip)

Fracture Healing

Finland, Italy, Sweden, United States, Belgium, Switzerland, Canada, Hong Kong, Hungary, Germany, Netherlands, Bulgaria, Australia, Poland, Greece, Denmark, United Kingdom, Estonia, India, New Zealand, Latvia, Lithuania, Argentina, Sl...
Santaris Pharma A/S

Completed

Multiple Ascending Dose Study of Miravirsen in Treatment-Naïve Chronic Hepatitis C Subjects

Hepatitis C

United States, Germany, Netherlands, Poland, Puerto Rico, Slovakia
LMU Klinikum
Seventh Framework Programme; NBIA Alliance

Recruiting

TIRCON International NBIA Registry (TIRCON)

Neurodegeneration With Brain Iron Accumulation (NBIA) | Pantothenate Kinase-associated Neurodegeneration (PKAN) | Aceruloplasminemia | Beta-Propeller Protein-Associated Neurodegeneration (BPAN) | Mitochondrial Membrane Protein Associated Neurodegeneration (MPAN) | Fatty Acid Hydroxylase-associated... and other conditions

Canada, Czechia, Germany, Italy, Netherlands, Poland, Serbia, Spain
Gilead Sciences

Completed

Evaluation of the Safety, Tolerability, Pharmacokinetics, and Activity of GS-9450 in Subjects With Chronic HCV

HCV Infection

United States, Netherlands, Germany
Erasmus Medical Center

Completed

Dutch Acute HCV in HIV Study (DAHHS-2): Grazoprevir/Elbasvir for Acute HCV (DAHHS-2)

Hepatitis C | Human Immunodeficiency Virus | Acute Hepatitis C

Netherlands, Belgium
Abbott

Completed

An Open-Label Study to Evaluate the Response to Adalimumab in Patients With Active Ankylosing Spondylitis Who Have Failed Standard Therapy or TNF-Alpha Inhibitors (RHAPSODY) (RHAPSODY)

Ankylosing Spondylitis

France, Germany, Greece, Italy, Switzerland, Spain, United Kingdom, Belgium, Austria, Netherlands, Norway, Denmark, Finland, Ireland, Sweden
Hoffmann-La Roche

Completed

A Study of Two Vismodegib Regimens in Participants With Multiple Basal Cell Carcinomas

Basal Cell Carcinoma

United States, Spain, France, Germany, Netherlands, Russian Federation, Italy, Mexico, Austria, Canada
UCB Biopharma SRL

Active, not recruiting

A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Subjects With Active Axial Spondyloarthritis Including Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis (BE MOVING)

Ankylosing Spondylitis | Axial Spondyloarthritis | r-axSpa | Nr-axSpa

United States, Belgium, Bulgaria, China, Czechia, France, Germany, Hungary, Japan, Netherlands, Poland, Spain, Turkey, United Kingdom
Ascendis Pharma Endocrinology Division A/S

Completed

A Trial to Compare the Efficacy and Safety of Once-weekly Lonapegsomatropin With Placebo and a Daily Somatropin Product in Adults With Growth Hormone Deficiency (foresiGHt)

Endocrine System Diseases | Growth Hormone Deficiency | Hormone Deficiency

United States, Armenia, Georgia, Turkey, Ukraine, Australia, Canada, Denmark, France, Germany, Greece, Israel, Italy, Japan, Korea, Republic of, Malaysia, Netherlands, New Zealand, Poland, Romania, Serbia, Slovakia, Spain, United Kingdom
AbbVie

Completed

A Study Evaluating the Safety and Efficacy of Upadacitinib in Adults With Active Ankylosing Spondylitis (SELECT-AXIS 1)

Ankylosing Spondylitis (AS)

United States, Australia, Belgium, Canada, Croatia, Czechia, Denmark, Finland, France, Germany, Hungary, Italy, Japan, Korea, Republic of, Netherlands, New Zealand, Poland, Portugal, Spain, Sweden, United Kingdom
Novartis Pharmaceuticals

Recruiting

A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission

Non-radiographic Axial Spondyloarthritis

Belgium, Netherlands, Italy, Thailand, Hungary, Malaysia, Germany, Israel, France, Czechia, Colombia, Romania, Poland, Turkey, Vietnam, Brazil, Mexico, Philippines
Denali Therapeutics Inc.
Takeda

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)

Frontotemporal Dementia

Spain, Turkey, France, Belgium, Netherlands, Portugal, Italy, Colombia, Czechia, Brazil, United Kingdom, Serbia
Novartis Pharmaceuticals

Completed

Study of PDR001 and/or MBG453 in Combination With Decitabine in Patients With AML or High Risk MDS

Myelodysplastic Syndromes | Bone Marrow Diseases | Hematologic Diseases | Leukemia | Leukemia, Myeloid | Leukemia, Myeloid, Acute | Preleukemia | Chronic Myelomonocytic Leukemia

United States, France, Australia, Netherlands, Spain, Germany, United Kingdom, Finland
Zimmer Biomet

Active, not recruiting

PMCF Study on the Safety and Performance of the Zimmer® Maxera™ Acetabular System in Total Hip Arthroplasty

Avascular Necrosis | Inflammatory Arthritis | Osteoarthritis, Hip | Congenital Hip Dysplasia | Post-traumatic; Arthrosis | Rheumatoid Arthritis With Adequate Bone Quality

Netherlands, Finland, Belgium, France, Spain, Australia, Canada, United Kingdom
Amsterdam UMC, location VUmc
Boehringer Ingelheim; Abbott

Unknown

MEDICLAS Study (Metabolic Effects of Different Classes of AntiretroviralS)

HIV Infections | HIV-Associated Lipodystrophy Syndrome

Finland, Netherlands, Spain, United Kingdom
McMaster University
Hamilton Health Sciences Corporation; Population Health Research Institute

Completed

HIP Fracture Accelerated Surgical TreaTment And Care tracK (HIP ATTACK) Trial (HIP ATTACK)

Hip Fractures

Canada, United Kingdom, South Africa, Netherlands, Italy, India, Pakistan, China, Belgium, France, United States, Spain, Colombia, Hong Kong, Malaysia, Poland, Thailand
Wave Life Sciences Ltd.

Terminated

Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD) (FOCUS-C9)

ALS | FTD

Canada, Belgium, New Zealand, Netherlands, Australia, Sweden, United Kingdom, Ireland
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Pasireotide Long Acting Release (LAR) vs. Octreotide LAR in Patients With Active Acromegaly

Acromegaly

United States, Germany, Italy, Belgium, Taiwan, Turkey, Switzerland, Israel, Netherlands, Sweden, United Kingdom, Korea, Republic of, Spain, France, Canada, Greece, Russian Federation, Denmark, Mexico, China, Hungary, Norway, Argentina and more
Novartis Pharmaceuticals

Completed

Effect of Secukinumab on Radiographic Progression in Ankylosing Spondylitis as Compared to GP2017 (Adalimumab Biosimilar) (SURPASS)

Ankylosing Spondylitis

Taiwan, Netherlands, United Kingdom, Germany, Korea, Republic of, Israel, United States, Belgium, Greece, Philippines, Russian Federation, Spain, Turkey, Portugal, Mexico, Peru, Denmark, France, Czechia, Australia, Canada, Poland, J... and more
PellePharm, Inc.

Completed

Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects With Basal Cell Nevus Syndrome (Gorlin Syndrome)

Basal Cell Nevus Syndrome

United States, Spain, Germany, United Kingdom, Italy, France, Belgium, Canada, Denmark, Netherlands
Novartis Pharmaceuticals

Completed

A Pharmacokinetic (PK) Study of Nilotinib in Pediatric Patients With Philadelphia Chromosome-positive (Ph+) Chronic Myelogenous Leukemia (CML) or Acute Lymphoblastic Leukemia (ALL)

Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia

Netherlands, Italy, France, United Kingdom
Biogen

Terminated

A Pharmacokinetics and Safety Study of BIIB132 in Adults With Spinocerebellar Ataxia 3

Spinocerebellar Ataxia Type 3

United States, Netherlands, Israel, Portugal, United Kingdom, Germany
Vico Therapeutics B. V.

Recruiting

A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD

Huntington Disease | Spinocerebellar Ataxia Type 3 | Spinocerebellar Ataxia Type 1

Israel, Germany, United Kingdom, Poland, Denmark, Netherlands, France
Jaeb Center for Health Research
Foundation Fighting Blindness

Active, not recruiting

Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A)

Usher Syndrome, Type 2A | Retinitis Pigmentosa 39

United States, Canada, France, Germany, Netherlands, United Kingdom
Population Health Research Institute
Canadian Institutes of Health Research (CIHR)

Recruiting

HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial (HIP ATTACK-2)

Myocardial Injury | Hip Fractures

United States, Hong Kong, Spain, Canada, Pakistan, South Africa, Netherlands, Malaysia, Finland, Australia, Belgium, Mexico, Nepal, Saudi Arabia, Chile, Italy, Poland, Brazil, India
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Terminated

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ACH-0137171 in Participants With Chronic Hepatitis C Infection

HCV Infection

United States, Germany, Netherlands
Gruppo Italiano Malattie EMatologiche dell'Adulto

Unknown

Phase IV EORTC Quality of Life Module for Patients With Chronic Myeloid Leukemia

Chronic Myeloid Leukemia

Germany, Italy, Austria, Iraq, United States, Brazil, China, Malaysia, Netherlands
ProQR Therapeutics

Active, not recruiting

Study to Evaluate the Efficacy Safety and Tolerability of Ultevursen in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Sirius)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, Netherlands, United Kingdom, Germany
Sanofi

Completed

Phase II, Open Label, Single Arm Study of SAR302503 In Myelofibrosis Patients Previously Treated With Ruxolitinib (JAKARTA2)

Hematopoietic Neoplasm

United States, Austria, Belgium, Canada, France, Germany, Italy, Netherlands, Spain, United Kingdom
Kiadis Pharma

Terminated

Efficacy and Safety of a Donor Lymphocyte Preparation Depleted of Functional Host Alloreactive T-cells (ATIR) in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor

Lymphoma | Myeloid Leukemia | Myeloproliferative Disorders | Multiple Myeloma | Myelodysplastic Syndrome | Lymphoblastic Leukemia

Canada, Netherlands, Germany, Belgium, United States, Italy, United Kingdom
Radboud University Medical Center
Bristol-Myers Squibb; Merck Sharp & Dohme LLC; Gilead Sciences; ViiV Healthcare; Janssen... and other collaborators

Recruiting

Pharmacokinetics of Antiretroviral Agents in HIV-infected Pregnant Women. (PANNA)

HIV Infections

Germany, United Kingdom, Netherlands, Belgium, Ireland, Italy, Spain
BioMarin Pharmaceutical

Completed

Long-Term Efficacy and Safety Extension Study of BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)

Morquio A Syndrome | MPS IVA | Mucopolysaccharidosis IV A

United States, Canada, France, Taiwan, Argentina, Colombia, Spain, Turkey, Japan, Saudi Arabia, Netherlands, Denmark, Korea, Republic of, Brazil, United Kingdom, Germany, Norway, Portugal, Italy, Qatar
Pfizer

Recruiting

Effectiveness of Treatment With Tofacitinib in Patients With Psoriatic Arthritis in Routine Clinical Practice

Psoriatic Arthritis

Israel, France, Spain, Finland, Netherlands, Belgium, Denmark, Sweden
AstraZeneca

Completed

Descriptive Study in Patients Treated With Vimovo™, Including Registration of the Physicians' Prescribing Patterns (CHARACTERIZE)

Osteoarthritis | Rheumatoid Arthritis | Ankylosing Spondylitis

Spain, United Kingdom, Finland, Norway, Belgium, Netherlands, Germany, Switzerland
Hoffmann-La Roche
Chugai Pharmaceutical

Active, not recruiting

Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria (COMPOSER)

Paroxysmal Hemoglobinuria, Nocturnal

France, Korea, Republic of, Italy, Japan, Germany, Hungary, Netherlands
Eli Lilly and Company

Completed

Second Study of the Effect of Teriparatide on Hip Fracture Healing

Femur Neck Fracture

Germany, United States, Belgium, France, Hungary, Croatia, Korea, Republic of, Greece, India, Switzerland, Romania, Netherlands, Poland, Turkey
Amgen

Completed

Phase II Study of Apremilast (CC-10004) in Adults With in Psoriatic Arthritis

Psoriatic Arthritis

Belgium, Canada, United Kingdom, Germany, Netherlands
Poitiers University Hospital
University Medical Center Groningen; Imperial College London; University of Liege and other collaborators

Recruiting

International Chronic Myeloid Leukemia Pediatric Study (ICMLPed)

Chronic Myeloid Leukemia

Denmark, China, Germany, Australia, Belgium, Brazil, Chile, Croatia, Czechia, France, Greece, Japan, Lebanon, Poland, Spain, Turkey, Austria, Belarus, Netherlands, Slovakia
Friedreich's Ataxia Research Alliance

Recruiting

Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study (UNIFAI)

Friedreich Ataxia

United States, Canada, New Zealand, Australia, France, Austria, Belgium, Brazil, Czechia, Germany, Greece, Ireland, Italy, Spain, United Kingdom, India, Netherlands
Gamida Cell ltd

Completed

Transplantation of NiCord®, Umbilical Cord Blood-derived Ex Vivo Expanded Cells, in Patients With HM

Hematological Malignancies | Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS)

United States, Singapore, Spain, Netherlands, Italy
CTI BioPharma

Terminated

Pacritinib Versus Best Available Therapy to Treat Myelofibrosis

Primary Myelofibrosis | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis

United States, Australia, Belgium, Czechia, France, Germany, Hungary, Italy, Netherlands, New Zealand, Russian Federation, United Kingdom
IntraBio Inc

Active, not recruiting

A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Germany, Slovakia, Netherlands, Czechia, Switzerland
PENTA Foundation
Medical Research Council; ANRS, Emerging Infectious Diseases

Completed

KONCERT A Kaletra ONCE Daily Randomised Trial of the Pharmacokinetics, Safety and Efficacy of Twice-daily Versus Once-daily Lopinavir/Ritonavir Tablets Dosed by Weight as Part of Combination Antiretroviral Therapy in Human Immunodeficiency Virus-1 (HIV-1) Infected Children (PENTA 18) (KONCERT)

Antiretroviral Therapy in HIV-1 Infected Children

Netherlands, Germany, United Kingdom, Ireland, Thailand
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Active, not recruiting

An Efficacy and Safety Study of Fedratinib Compared to Best Available Therapy in Subjects With DIPSS-intermediate or High-risk Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, or Post-essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib (FREEDOM2)

Primary Myelofibrosis | Myelofibrosis | Post-Polycythemia Vera

Australia, Austria, Belgium, China, Czechia, France, Germany, Hungary, Italy, Korea, Republic of, Netherlands, Poland, Russian Federation, Spain, Ireland, United Kingdom
Novartis Pharmaceuticals

Completed

Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload

Myelofibrosis | Sickle Cell Disease | Thalassemia | Diamond Blackfan Anemia

United States, Netherlands, Taiwan, Thailand, Italy, Germany, Spain, Canada, Belgium, Greece, Turkey, United Kingdom
European LeukemiaNet

Completed

European Stop Tyrosine Kinase Inhibitor Study (EURO-SKI)

Chronic Myeloid Leukemia

France, Denmark, Norway, Sweden, Czechia, Portugal, Germany, Netherlands, Finland, Greece

Clinical Trials on Degeneration; Bone in Netherlands

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