Clinical Trials on Degenerative Disease in South Africa

Total 18763 results

Willem Daniel Francois Venter
Medical Research Council, South Africa

Completed

Evaluation of Low-dose Darunavir in a Switch Study (DRV)

HIV Infections

South Africa
Barbara Ensoli, MD
Italian Ministry of Foreign Affairs - General Direction for Cooperation and...

Completed

A Phase Il of a Therapeutic, Recombinant, Biologically Active HIV-1 Tat Protein Vaccine in HIV-Infected, Anti-Tat Negative, ARV-Treated Adult Volunteers (ISS T-003)

HIV Infections

South Africa
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Voluntary HIV Counseling, Testing, and Medication for Pregnant Women to Prevent Mother-to-Child HIV Transmission

HIV Infections

South Africa
Novartis

Completed

A Quality of Life and Safety Study With Pimecrolimus Cream, 1% in Children (Age 2-12 Years) With Atopic Dermatitis

Atopic Eczema

South Africa
University of Pretoria
South African Sugar Association

Completed

Nutrition Education Intervention for Adults With Type 2 Diabetes

Type 2 Diabetes Mellitus

South Africa
Vanderbilt University Medical Center
National Institute of Mental Health (NIMH)

Completed

Traditional Healer-initiated HIV Counseling and Testing in South Africa

HIV Infection

South Africa
IDinsight
Reach Digital Health (formerly Praekelt.org)

Recruiting

Testing Content Delivery Models for MomConnect (MQR)

Hematological Diseases | Breastfeeding | Immunization Coverage

South Africa
Sanofi

Completed

Antibody Persistence in Healthy Children After Primary and Booster DTaP-IPV-Hep B-PRP-T Vaccine or Control Vaccine

Hepatitis B | Whooping Cough | Tetanus | Diphtheria | Poliomyelitis

South Africa
Medicines for Malaria Venture
University of Cape Town

Completed

Phase I Study of Ascending Doses of MMV390048 in Healthy Adult Volunteers

Malaria

South Africa
University of Johannesburg

Completed

The Efficacy of Sodium Shale Oil Sulponate 1% Shampoo in the Treatment of Pityriasis Capitis

Dandruff

South Africa
Medicines for Malaria Venture
University of Cape Town

Terminated

Safety, Tolerability & Pharmacokinetics (PK) of Co-administered Single Doses of OZ439 and Mefloquine (MQ) in Healthy Volunteers

Malaria

South Africa
Code Pharma

Recruiting

Phase IIa Randomized Placebo Controlled Clinical Study of Codivir in Hospitalized Patients With Moderate COVID-19

COVID-19

South Africa
University of Witwatersrand, South Africa

Terminated

Differences Between Stavudine and Tenofovir Each Combined With Lamivudine and Efavirenz in SA HIV-infected Patients (CHRU01)

Metabolic Complications | Mitochondrial Toxicity

South Africa
Convergence Pharmaceuticals

Completed

Efficacy and Safety of CNV2197944 Versus Placebo in Patients With Post-herpetic Neuralgia

Post-herpetic Neuralgia

South Africa
Wits Health Consortium (Pty) Ltd
Discovery Vitality

Active, not recruiting

Testing the Effectiveness of Different Messaging Approaches to Increase Doctor Visits Amongst Individuals With Risk Factors for Diabetes

Type 2 Diabetes | Pre-diabetes

South Africa
Zimmer Biomet
University of Cape Town

Completed

Sternal Closure With SternaLock 360: First in Man Study (SL360)

Sternal Fracture

South Africa
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Innovations in HIV Testing (TI)

Human Immunodeficiency Virus

South Africa
Boston University
United States Agency for International Development (USAID)

Withdrawn

Impact of Anti-HIV Treatment on Labor Productivity and Costs in South Africa

HIV Infections

South Africa
Barbara Ensoli, MD, PhD
Italian Ministry of Foreign Affairs - General Direction for Cooperation and...

Completed

A Roll-over Observational Study for the Extended Follow-up of the Volunteers of the ISS T-003 Trial (ISST-003EF-UP)

HIV Infections

South Africa
University of Witwatersrand, South Africa
University of Colorado, Denver; Emory University; Bill and Melinda Gates Foundation

Completed

Influenza Vaccine Trial in HIV Uninfected Pregnant Women (MatfluHIVneg)

Influenza

South Africa
Microbiome Health Research Institute
University of Cape Town

Terminated

Transfer of Healthy Gut Flora for Restoration of Intestinal Microbiota Via Enema for Patients in the Rehabilitative Phase of Malnutrition (THRIVE)

Moderate Acute Malnutrition | Severe Acute Malnutrition

South Africa
Alvotech Swiss AG

Active, not recruiting

Multicenter Study in Postmenopausal Women With Osteoporosis, ALVOBOND (ALVOBOND)

Osteoporosis, Postmenopausal

South Africa
University of Pennsylvania
Bill and Melinda Gates Foundation; Wits Reproductive Health and HIV Institute

Completed

Incentives to Promote Sustained Linkage to HIV Care

HIV/AIDS | Human Immunodeficiency Virus

South Africa
Peter Siesjö
University of Stellenbosch

Completed

Effect of Antisecretory Factor, Given as a Food Supplement to Adult Patients With Severe Traumatic Brain Injury (SASAT)

Brain Trauma

South Africa
FHI 360
Foundation for Professional Development; Future Families

Completed

Evaluation of an Integrated Economic Strengthening and HIV Prevention Program for Vulnerable Youth in South Africa (ASPIRES)

HIV Infections | HIV

South Africa
Novartis Pharmaceuticals

Completed

A Comparison of Ranibizumab and Aflibercept for the Development of Geographic Atrophy in (Wet) AMD Patients (RIVAL)

Age-Related Macular Degeneration

Australia
Council for Scientific and Industrial Research,...
Royal College of Surgeons, Ireland; European Union

Completed

Solar Disinfection of Drinking Water (SODISWATER)

Diarrhea | Dysentery (Bloody Diarrhea)

South Africa
University of Witwatersrand, South Africa

Unknown

Safety and Immunogenicity of Measles Vaccine, Varicella Vaccine and Hepatitis-A Vaccine (MV/VV/Hep-AV)

Measles | Hepatitis A | Varicella

South Africa
University of Johannesburg

Completed

Venavine Intensive® in the Treatment of Symptoms Associated With Chronic Venous Insufficiency

Venous Insufficiency

South Africa
University of Witwatersrand, South Africa
SynaVir

Completed

Study of Oral Administration of Ribavirin and Nitazoxamide Versus Placebo in COVID-19 (DuACT)

Covid19 | SARS-CoV Infection

South Africa
Harvard School of Public Health (HSPH)
University of Heidelberg Medical Center; University of Witwatersrand, South...

Unknown

Home HIV Testing for Older Adults in South Africa (Test@Home)

HIV Infections | Knowledge, Attitudes, Practice

South Africa
Boston University
Bill and Melinda Gates Foundation; University of Witwatersrand, South Africa

Withdrawn

Evaluation of Six-month HIV Treatment Dispensing in South Africa

HIV

South Africa
Michael Hoelscher
Radboud University Medical Center; German Federal Ministry of Education and... and other collaborators

Completed

BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)

Pulmonary Tuberculoses | Other Specified Pulmonary Tuberculosis

South Africa
University of Witwatersrand, South Africa

Completed

Effect of HIV and/or Active Tuberculosis on the Immune Responses to Trivalent Influenza Vaccine (TIV) in Adults (TIV_HIV_TB)

HIV | Tuberculosis | Influenza

South Africa
University of Witwatersrand, South Africa

Completed

Efficacy of Influenza Vaccine in HIV Infected Adults

HIV Infections | HIV | Influenza | Vaccination

South Africa
University of California, San Francisco
National Institutes of Health (NIH); ANOVA Health Institute

Completed

Peer Navigation to Improve Engagement in Care for HIV-Positive Men Who Have Sex With Men in Ehlanzeni, South Africa

Hiv

South Africa
University of Witwatersrand, South Africa
Massachusetts General Hospital; Emory University; UMC Utrecht

Recruiting

iHEART-SA Intervention Study (iHEART-SA)

Hypertension | HIV

South Africa
University of Witwatersrand, South Africa
UNITAID

Completed

CHARACTERISE - A Cross-sectional, Observational Study to Characterise the Transition to Dolutegravir-based Regimens in South Africa in Terms of the Emergence of Obesity, Viral Re-suppression and Integration Into Routine Programme Care (CHARACTERISE)

Dolutegravir

South Africa
University of North Carolina, Chapel Hill
National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of Stellenbosch and other collaborators

Completed

The Trajectory of Fetal Alcohol Spectrum Disorders (FASD) Across the Life Span: Continuing Prevention and Longitudinal Epidemiology

Fetal Alcohol Spectrum Disorders

South Africa
University of Witwatersrand, South Africa

Completed

Influenza Vaccine in HIV Infected Children

Influenza With Pneumonia, Influenza Virus Identified

South Africa
University of Johannesburg

Completed

Efficacy of Homoeopathy and Physiotherapy in Chronic Low Back Pain Due to Osteoarthritis

Osteoarthritis

South Africa
Shabir Madhi

Not yet recruiting

Pertussis Vaccination Among HIV-infected and HIV-uninfected Pregnant Women

dTap Vaccine

South Africa
University of Johannesburg

Completed

An Observational Study on the Efficacy of Individualised Homoeopathic Treatment on Premenstrual Syndrome

Premenstrual Syndrome

South Africa
Children's Mercy Hospital Kansas City
University of the Western Cape

Completed

Adapting the Diabetes Prevention Program for a Developing World Context

Weight Loss

South Africa
GlaxoSmithKline

Completed

An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary Tuberculosis

Tuberculosis

South Africa
National Institute of Environmental Health Sciences...

Completed

Study of DDT and Loss of Clinically-Recognized Pregnancies in South Africa

HIV Infections | Malaria | Pregnancy Outcome | Stillbirth | Spontaneous Abortion

South Africa
Find
University of Cape Town; Universidad Peruana Cayetano Heredia

Unknown

Performance Evaluation of TB Breath- and Cough-testing Platforms

Diagnoses Diseases | Pulmonary TB

South Africa
UNC Lineberger Comprehensive Cancer Center
Fogarty International Center of the National Institute of Health

Completed

Finding Barriers and Designing Solutions to Promote Women s Cancer Screening in South Africa (FIND)

Cervical Cancer

South Africa
Wellcome Trust Liverpool Glasgow Centre for Global...
Professor David Lalloo; Professor Hamish Simpson; Professor William J Harrison; Professor Sithombo Maqungo

Unknown

HIV in Orthopaedic Skeletal Trauma Study (HOST)

Fracture Healing in HIV-positive Patients

South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Using Biomarkers to Predict TB Treatment Duration

Pulmonary Tuberculosis

South Africa

Clinical Trials on Degenerative Disease in South Africa

Sponsors and Collaborators

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Drug Interventions

CROs by country

CROs in Myanmar

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Rare Diseases

Drug Interventions

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