Clinical Trials on Dementia Moderate

Total 5517 results

Institute for Neurodegenerative Disorders

Completed

Evaluation of [18F] FEPPA and PET Imaging as a Marker of Inflammation in Subjects With Neurological Conditions

Multiple Sclerosis | Parkinson Disease | Alzheimer Disease

United States
Christian Baumann
ETH Zurich

Recruiting

Assessing the Symptomatic Benefit of Acoustic Slow Wave Enhancement in Parkinson Disease

Parkinson Disease | Mild Cognitive Impairment | Huntington Disease

Switzerland
University of Miami

Recruiting

Clinical Applications of Advanced Ophthalmic Imaging

Multiple Sclerosis | Diabetic Retinopathy | Dementia | Dry Eye Syndromes | Presbyopia | Myopia

United States
Chang Gung Memorial Hospital

Enrolling by invitation

The Relationship Between Obstructive Sleep Apnea and Alzheimer's Disease: Evidence and Effectiveness (OSA)

Mild Cognitive Impairment | Obstructive Sleep Apnea of Adult

Taiwan
University Hospital, Montpellier
Assistance Publique - Hôpitaux de Paris; University Hospital, Clermont-Ferrand and other collaborators

Terminated

In Vivo Alzheimer Proteomics (PROMARA)

Parkinson Disease | Brain Trauma | Probable Alzheimer Disease | Neurological Disease Without Cognitive Degradation | Acute Hydrocephaly

France
University of Southern California
United States Department of Defense; Northern California Institute of Research... and other collaborators

Completed

A Study of Brain Aging in Vietnam War Veterans (DOD-ADNI)

Traumatic Brain Injury | Post Traumatic Stress Disorder | Mild Cognitive Impairment | Alzheimer's Disease

United States
China Medical University Hospital

Unknown

Study of the Role of G72 in Amyotrophic Lateral Sclerosis: Biomarker Discovery and Mechanism Investigation

Parkinson's Disease | Amyotrophic Lateral Sclerosis | Alzheimer Disease
O & O Alpan LLC

Unknown

Investigating Lysosomal Storage Diseases in Minority Groups

Fabry Disease | Niemann-Pick Disease | Gaucher Disease | Pompe Disease | Lysosomal Storage Disorders

United States
Cedars-Sinai Medical Center

Completed

Memory Disorders Registry

Parkinson Disease | Dementia | Huntington Disease | Alzheimer's Disease

United States
IRCCS San Camillo, Venezia, Italy
IRCCS Centro San Giovanni di Dio Fatebenefratelli; Università Ca' Foscari Venezia

Recruiting

Exploring the Gut-Brain Axis in Ageing and Neurodegeneration (GutBrain)

Multiple Sclerosis | Healthy | Parkinson Disease | Prodromal Alzheimer's Disease

Italy
Centre Hospitalier Universitaire de Saint Etienne
Association Lyonnaise de Logistique Posthospitalière

Terminated

Sleep Apnea in Early to Mid-Stage Alzheimer's Disease (AZAP)

Alzheimer Disease | Early Onset Alzheimer Disease | Obstructive Sleep Apnea Syndromes

France
Vanderbilt University Medical Center

Not yet recruiting

Voice and Swallowing Disorders in Adults With and Without Alzheimer's Disease

Alzheimer Disease | Caregiver Burden | Dysphagia | Healthy Aging | Dysphonia
St. Joseph's Hospital and Medical Center, Phoenix
Texas Tech University

Not yet recruiting

MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease

Cognitive Dysfunction | Neurodegenerative Disease, Hereditary | Cognitive Impairment, Mild | Amyloid Plaque | Inflammation, Brain
Azienda Ospedaliera di Perugia

Recruiting

PIPAF Platelets in the Pathogenesis of Ageing Associated Frailty (PIPAF)

Coronary Artery Disease | Diabetes Mellitus, Type 2 | Alzheimer Disease

Italy
National Institute of Neurological Disorders and...

Completed

Diagnosis and Natural History Study of Patients With Neurological Conditions

Parkinson's Disease | Dementia | Multiple System Atrophy | Alzheimer's Disease | Movement Disorder

United States
MD Stem Cells

Recruiting

Neurologic Stem Cell Treatment Study (NEST)

Stroke | Nervous System Diseases | Diabetic Neuropathies | Neurodegenerative Diseases | Cognitive Impairment | Amyotrophic Lateral Sclerosis | Dementia | Neurological Disorders | Alzheimer Disease | ALS | Traumatic Brain Injury | Cerebral Infarction | Lewy Body Disease | Cerebral Hemorrhage | Frontotemporal Dementia | Progressive... and other conditions

United States, United Arab Emirates
Kaiser Permanente
Patient-Centered Outcomes Research Institute

Terminated

Comparative Trial of Home-Based Palliative Care (HomePal)

End Stage Liver Disease | Heart Failure | Cancer | Chronic Obstructive Pulmonary Disease | Neuromuscular Diseases | Dementia | End Stage Renal Disease

United States
University College, London
Washington University School of Medicine; University of Washington; Alzheimer... and other collaborators

Not yet recruiting

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK (NIO-SILK)

Alzheimer Disease | Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) | Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 2 (Disorder) | Autosomal Dominant Alzheimer Disease Due to Mutation of Amyloid Precursor Protein (Disorder)
M.D. Anderson Cancer Center

Recruiting

Early Assessment of Ovarian Cancer Aggressiveness by Metabolic Imaging

Ovarian Cancer

United States
Dalin Tzu Chi General Hospital

Completed

Vegetarian Diet and Chronic Degenerative Diseases

Depression | Cardiovascular Diseases | Stroke | Dementia | Cataract | Urinary Tract Infections | Gout | Gallstone

Taiwan
Indiana University

Recruiting

Intervention to Change Affect Recognition and Empathy (ICARE)

Traumatic Brain Injury | Concussion, Severe | Concussion, Intermediate | Concussion With Brief Loss of Consciousness | Traumatic Brain Injury With Brief Loss of Consciousness | Traumatic Brain Injury With No Loss of Consciousness | Concussion With LOC 31 to 59 Minutes | Traumatic Brain Injury With... and other conditions

United States
Neuromed IRCCS

Enrolling by invitation

Psychometric Evaluation in Patients With Brain Damage During Neuroinflammation (NeuroPsyc) (NeuroPsyc)

Stroke | Epilepsy | Multiple Sclerosis | Parkinson Disease | Dementia

Italy
Auburn University

Completed

Auburn University Research on Olive Oil for Alzheimer's Disease (AU-ROOAD) ((AU-ROOAD))

Alzheimer Disease | Cerebral Amyloid Angiopathy

United States
AIO-Studien-gGmbH
Novartis Pharmaceuticals; Assign Data Management and Biostatistics GmbH

Completed

Safety and Tolerability of Everolimus as Second-line Treatment in Poorly Differentiated Neuroendocrine Carcinoma / Neuroendocrine Carcinoma G3 (WHO 2010) and Neuroendocrine Tumor G3 - an Investigator Initiated Phase II Study (EVINEC)

Neuroendocrine Carcinoma, Grade 3 | Poorly Differentiated Malignant Neuroendocrine Carcinoma | Neuroendocrine Carcinoma, Grade 1 [Well-differentiated Neuroendocrine Carcinoma] That Switched to G3 | Neuroendocrine Carcinoma, Grade 2 [Moderately Differentiated Neuroendocrine Carcinoma]... and other conditions

Germany
McMaster University
Canadian Institutes of Health Research (CIHR)

Recruiting

Relative Impacts on Preventative Primary Care--a Longitudinal Evaluation of COVID-19:Phase 1 (RIPPLE-C)

Diabetes Mellitus | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Osteoarthritis | Dementia | Congestive Heart Failure | Depression, Anxiety

Canada
AC Immune SA
Worldwide Clinical Trials

Recruiting

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

Alzheimer's Disease | Prodromal Alzheimer's Disease | Amyloid Plaque | Beta-Amyloid | Alzheimer's Disease in Down Syndrome

United States, Spain, United Kingdom
Pacific Coast Family Medical Group

Enrolling by invitation

Disease Prevention in Clinical Practice Base on Patient Specific Physiology (STOPDISEASE)

Cancer | Atherosclerosis | Atrial Fibrillation | Insulin Resistance | Dementia | PreDiabetes | Type2 Diabetes | NASH - Nonalcoholic Steatohepatitis | Diastolic Dysfunction | Carotid Plaque
Bristlecone Health, Inc.
University of Minnesota

Unknown

Photobiomodulation & Ketogenic Diet for Treatment of Mid-periphery Retinal Disorders for Alzheimer's Disease Prevention

Diabetic Macular Edema (DME) | Age-related Macular Degeneration (AMD) | Diabetic Retinopathy (DR) | Mid-peripheral Drusen Formation

United States
Uniformed Services University of the Health Sciences
University of California, San Francisco

Withdrawn

Clinical Characteristics of Dementias That Occur Remotely After Traumatic Brain Injury in Retired Military Personnel

Dementia | Mild Cognitive Impairment (MCI) | Traumatic Brain Injury (TBI) | Post-traumatic Stress Disorder (PTSD) | Chronic Traumatic Encephalopathy (CTE)

United States
Sanpasitthiprasong Hospital
Dementia Association of Thailand; Diabetes Association of Thailand; The Endocrine... and other collaborators

Active, not recruiting

Impact of Lifestyle Modification on the Development of Dementia, Chronic Kidney Disease, Diabetes, Chronic Obstructive Pulmonary Disease, Cancers and Cardiovascular Disease in a Thai General Population

Cardiovascular Diseases | Diabetes Mellitus | Chronic Obstructive Pulmonary Disease | Dementia | Chronic Kidney Disease | Malignancy

Thailand
Vico Therapeutics B. V.

Recruiting

A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD

Huntington Disease | Spinocerebellar Ataxia Type 3 | Spinocerebellar Ataxia Type 1

Israel, Germany, United Kingdom, Poland, Denmark, Netherlands, France
IGC Pharma LLC

Recruiting

IGC-AD1 Trial on Agitation in Dementia Due to Alzheimer's (IGC-AD1-P2)

Aggression | Depression | Anxiety | Alzheimer Disease | Memory Impairment | Agitated; State, Acute Reaction to Stress | Agitation,Psychomotor | Care Giving Burden | NPS | Aggressive Outburst

United States, Canada, Puerto Rico
The Leeds Teaching Hospitals NHS Trust
University of Leeds

Not yet recruiting

Amyloid Proteins From Medullary Thyroid Cancer and Laryngeal Amyloidosis

Dementia | Alzheimer Disease | Amyloid | Medullary Thyroid Cancer
Rutgers, The State University of New Jersey

Recruiting

Using Wearable and Mobile Data to Diagnose and Monitor Movement Disorders

Parkinson Disease | Movement Disorders | Huntington Disease | Essential Tremor | Spinocerebellar Ataxias | Dystonia, Primary

United States
University of North Carolina, Greensboro

Completed

Rhythmically Entrained Exercise in Community-Dwelling Older Adults (REECO)

Depression | Cognitive Impairment | Cognitive Dysfunction | Dementia | Alzheimer Disease | Exercise | Caregiver Burden | Healthy Aging | Fall | Mild Cognitive Impairment | Elderly | Executive Function | Gait | Mental Health | Cognitive Decline | Memory Disorders | Memory Impairment | Walking | Cognition | Physical Exertion | Music Therapy and other conditions

United States
Parc Sanitari Pere Virgili
Althaia Xarxa Assistencial Universitària de Manresa; Hospital Vall d'Hebron; Consorci... and other collaborators

Completed

Diabetes as an Accelerator of Cognitive Impairment and Alzheimer's Disease (DIALCAT)

Patients Aged 65-85 (Both Included) | Diagnosed of Mild Cognitive Impairment | Diagnosed of Type 2 Diabetes in Active Treatment (Hypoglycemic Agents) for a Period ≥5 Years

Spain
Luye Pharma Group Ltd.

Not yet recruiting

A Phase 1, SAD Study to Evaluate the Safety and Tolerability of LY03017

Negative Symptoms of Schizophrenia | Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis | Hallucinations and Delusions Associated With Parkinson Disease Psychosis

China
Fundació Institut de Recerca de l'Hospital de la...

Unknown

Sleep in Adults With Down Syndrome and Alzheimer's Disease

Obstructive Sleep Apnea | Alzheimer's Disease | Sleep Disturbances

Spain
Zhujiang Hospital

Not yet recruiting

Effectiveness of Atorvastatin in Preventing Cerebrovascular Events After Flow Diverter Implantation

Efficacy Endpoint: no New Cerebrovascular Adverse Events Within 1 Year | Safety Endpoint: no New Moderate or Serious Adverse Events Within 1 Year | All-cause Mortality Events (Within 1 Year) | Incident Ischemic Stroke Events (Within 1 Year) | New Hemorrhagic Stroke Events (Within 1 Year) | New... and other conditions
Masonic Cancer Center, University of Minnesota

Terminated

Hematopoietic Stem Cell Transplantation (HCT) for Inborn Errors of Metabolism

Sphingolipidoses | Niemann-Pick Disease, Type C | Krabbe Disease | Sly Syndrome | Fucosidosis | Aspartylglucosaminuria | Alpha Mannosidosis | Hurler's Syndrome | Maroteaux-Lamy Syndrome | Wolman's Disease | Niemann-Pick Disease Type B

United States
Masonic Cancer Center, University of Minnesota

Completed

Stem Cell Transplant for Inborn Errors of Metabolism

Niemann-Pick Disease | Wolman Disease | Adrenoleukodystrophy | Batten Disease | Metachromatic Leukodystrophy | GM1 Gangliosidosis | Fucosidosis | Globoid Cell Leukodystrophy | Gaucher's Disease | Tay Sachs Disease | Sandhoff Disease

United States
Centre Hospitalier Universitaire de Besancon
Novartis Pharmaceuticals; National Cancer Institute, France; National Research... and other collaborators

Terminated

Multicenter Prospective Cohort of Informal Caregivers in Burgundy and Franche-Comté (ICE)

Breast Cancer | Ischemic Stroke | Parkinson Disease | Age-related Macular Degeneration | Colorectal Cancer | Alzheimer Disease | Prostate Cancer | Hemorrhagic Stroke | Cardiac Disease

France
Central Clinical Hospital of the Russian Academy...
Ural State Medical University; De Haar Research Task Force; De Haar Research... and other collaborators

Terminated

Natural History of Coronary Atherosclerosis in Real-World Stable Chest Pain Patients Underwent Computed Tomography Angiography in Comparison With Invasive Multimodality Imaging (REALITY)

Coronary Artery Disease | Alzheimer Disease | Contrast-induced Nephropathy | Coronary Atherosclerosis | Cerebrovascular Disease | Stable Chronic Angina | Chronic Coronary Insufficiency

Netherlands, Russian Federation, Estonia
Centre Hospitalier Régional d'Orléans

Completed

Latest Imaging SPECT System Evaluation Phase 1 (LISSE1)

Heart Diseases | Neoplasms | Kidney Diseases | Parathyroid Diseases | Thyroid Diseases | Parkinsonian Disorders | Dementia | Pulmonary Embolism | Rheumatic Disease

France
Massachusetts General Hospital
ALS Association

Completed

Electronic-health Application To Measure Outcomes REmotely Clinical Trial (EAT MORE)

Parkinson's Disease | Amyotrophic Lateral Sclerosis | Weight Loss | Cachexia | Huntington's Disease | Neurodegenerative Disease

United States
Faculty of Medicine, Tarumanagara University
Hana Old Age Home

Unknown

Determinants of Cognitive Impairment Among Geriatrics

Depression | Hypertension | Obesity | Diabetes | Osteoarthritis | Cognitive Impairment | Dyslipidemias | Dementia | Mobility Limitation | Hearing Impairment | Vision Impairment and Blindness | Central Obesity

Indonesia
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Honolulu Heart Program

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Heart Failure | Coronary Disease | Hypertension | Lung Diseases, Obstructive | Chronic Obstructive Pulmonary Disease | Asthma | Dementia | Emphysema | Bronchitis | Cerebrovascular Accident | Aortic Aneurysm, Abdominal | Heart Failure, Congestive
Neuromed IRCCS
IRCCS Multimedica

Recruiting

Biomarkers of Synaptic Damage in Multiple Sclerosis

Multiple Sclerosis | Parkinson Disease | Amyotrophic Lateral Sclerosis | Alzheimer Disease

Italy
Nestlé
Nestec Ltd.; Regulatory and Clinical Research Institute Inc; Cytel Inc.

Terminated

Videofluoroscopic Swallowing Study (VFSS) (PORSCHE)

Stroke | Multiple Sclerosis | Parkinson Disease | Dementia | Alzheimer Disease | Oropharyngeal Dysphagia

United States, Finland
National Taiwan University Hospital

Completed

Application of Amyloid PET in Cerebral Amyloid Angiopathy (CAA)

Alzheimer Disease | Intracranial Hemorrhages | Cerebral Amyloid Angiopathy

Taiwan

Clinical Trials on Dementia Moderate

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