Clinical Trials on Depression Severe in Japan

Total 133 results

Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase 2 Trial of OPC-64005 for Major Depressive Disorder

Major Depressive Disorder

Japan
Kibi International University

Completed

Study Protocol for a Smartphone Application-based Intervention for Subthreshold Depression

Subthreshold Depression

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Study of Brexpiprazole in Patients With Major Depressive Disorder

Major Depressive Disorder

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Long-Term Study of Brexpiprazole in Patients With Major Depressive Disorder

Major Depressive Disorder

Japan
Gunma University

Completed

Treating Depressed Mood With a Smartphone-delivered Positive Word Stimulation for Subthreshold Depression

Subthreshold Depression

Japan
Kibi International University

Completed

Smartphone Intervention for Subthreshold Depression

Subthreshold Depression

Japan
Showa University

Completed

Analisis of Facors Involved in Antidepressant Treatment Response of Major Depressive Disorder (AFADTRMDD)

Major Depressive Disorder

Japan
Astellas Pharma Inc

Completed

Study to Evaluate Safety and Tolerability of FK949E in Elderly Patients With Major Depressive Disorder

Major Depressive Disorder Patients

Japan
Astellas Pharma Inc

Completed

Study to Evaluate Safety and Tolerability of FK949E in Patients With Major Depressive Disorder

Major Depressive Disorder Patients

Japan
Astellas Pharma Inc

Completed

Comparison of Plasma Concentration Changes Between Two Types of Tablets of FK949E Administration to Patients With Major Depressive Disorder

Major Depressive Disorder

Japan
Astellas Pharma Inc

Completed

Oral Multiple-dose Study in Patients With Major Depressive Disorder

Major Depressive Disorder

Japan
Nagoya City University

Completed

Brief Multifamily Psychoeducation for Families of Patients With Chronic Major Depression

Major Depressive Disorder

Japan
Astellas Pharma Inc

Completed

Study to Evaluate the Effect and Safety of Quetiapine Extended Release (XR) (FK949E) in Major Depressive Disorder

Major Depressive Disorder

Japan
Shionogi
Eli Lilly and Company

Completed

A Study of Duloxetine (LY248686) in Japanese Children and Adolescents With Depressive Disorder

Depressive Disorder

Japan
Shionogi
Eli Lilly and Company

Terminated

A Study of Duloxetine (LY248686) in the Treatment of Japanese Children and Adolescents With Depressive Disorder

Depressive Disorder

Japan
Kyoto University
Nagoya City University

Completed

Telephone Cognitive-Behavioral Therapy (CBT) for Subthreshold Depression and Presenteeism in Workplace

Depression

Japan
University of Jazan
Saudi Board of Community Medicine

Completed

Effects of an Educational Program on Depression Literacy and Stigma Among Secondary School Students in Jazan City

Depression Literacy | Depression Stigma

Saudi Arabia
GlaxoSmithKline

Completed

Study Of Bupropion SR (323U66) In Patients With Major Depressive Disorder In Japan

Major Depressive Disorder (MDD)

Japan
Kyoto University
National Center of Neurology and Psychiatry, Japan

Completed

Strategic Use of New Generation Antidepressants for Depression (SUN(^_^)D)

Unipolar Major Depressive Episode

Japan
Chiba University

Completed

An Open Study of Tipepidine Hibenzate in Adolescent Patients With Depression

Adolescent | Depression

Japan
Tokyo Medical University
University of Toyama; China Medical University, Taiwan; Chiba University; Japan...

Completed

The Synchronized Trial on Expectant Mothers With Depressive Symptoms by Omega-3 PUFAs (SYNCHRO): Open Trial

Depression | Pregnancy

Taiwan, Japan
Eli Lilly and Company

Completed

A Study of LY2216684 in Participants With Major Depression Disorder

Major Depressive Disorder

Japan
Tokyo Medical University
University of Toyama; China Medical University, Taiwan; Chiba University; Japan... and other collaborators

Completed

The Synchronized Trial on Expectant Mothers With Depressive Symptoms by Omega-3 PUFAs (SYNCHRO)

Depression | Pregnancy

Japan, Taiwan
Nagoya City University
Kochi University

Completed

Brief Behavioral Therapy for Insomnia (bBT-I) for Depressed Outpatients With Refractory Insomnia

Major Depressive Disorder

Japan
GlaxoSmithKline

Completed

Study Of 323U66 SR In Major Depressive Disorder

Depressive Disorder

Japan
Kibi International University

Unknown

iPad Application-based Intervention for Post-stroke Depression

Post-stroke Depression

Japan
Novartis Pharmaceuticals

Completed

Study of Efficacy, Safety, Tolerability and Pharmacokinetics of MIJ821 in Participants With Treatment- Resistant Depression (TRD)

Treatment-Resistant Depression

Spain, Japan, Poland, United States
Eli Lilly and Company

Completed

A Study of Fluoxetine in Major Depressive Disorder (MDD) Short-Term Dosing

Major Depressive Disorder

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Study of Aripiprazole as an Adjunctive Therapy in Patients With Major Depressive Disorder

Major Depressive Disorder

Japan
Eli Lilly and Company

Completed

A Study of Fluoxetine in Major Depressive Disorder (MDD) Long-Term Dosing

Major Depressive Disorder

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Long-Term Administration Study of Aripiprazole as an Adjunctive Therapy in Patients With Major Depressive Disorder

Major Depressive Disorder

Japan
Pfizer

Completed

Study Evaluating Long-Term Safety of Desvenlafaxine Succinate Sustained Release With Japanese Adult Subjects in Major Depressive Disorder (MDD)

Major Depressive Disorder

Japan
AbbVie

Completed

Study of AGN-151586 in Japanese Participants With Moderate to Severe Glabellar Lines

Moderate to Severe Glabellar Lines

Japan
GlaxoSmithKline

Completed

Controlled-release Paroxetine in Major Depressive Disorder (Double-blind, Placebo-controlled Study)

Depressive Disorder

Korea, Republic of, Japan
Sumitomo Pharma Co., Ltd.

Completed

A Phase III Study of SM-13496 in Patients With Bipolar I Depression.

Bipolar Depression

Lithuania, Malaysia, Russian Federation, Slovakia, Ukraine, Japan, Philippines, Taiwan
Takeda

Completed

The Exploratory Study to Investigate the Effect of Ramelteon for Insomnia Patients With Major Depressive Disorder by Using Actigraphy

Insomnia | Major Depressive Disorder

Japan
GlaxoSmithKline

Terminated

Paxil Japanese Post Marketing Paediatric Study in Depression (Double-blind, Placebo Controlled Study)

Depressive Disorder

Japan
Daiichi Sankyo Co., Ltd.

Completed

Study of CS-3150 in Patients With Severe Hypertension

Severe Hypertension

Japan
Solvay Pharmaceuticals

Completed

Fluvoxamine Maleate in the Treatment of Depression/Depressive State : A Post-marketing Clinical Study in Children and Adolescents

Major Depressive Disorder

Japan
GlaxoSmithKline

Completed

Study In Patients With Depression Not Responding to Selective Serotonin Re-uptake Inhibitors

Depressive Disorder

Japan
Sunovion

Completed

A Clinical Study to Test the Effectiveness of an Investigational Drug to Treat People That Have Major Depressive Episodes When They Have Bipolar 1 Depression

Depressive Episode | Bipolar 1 Depression

Japan, Serbia, United States, Poland, Russian Federation, Bulgaria, Slovakia, Ukraine
National Center of Neurology and Psychiatry, Japan

Terminated

Transcranial Direct Current Stimulation for Depression in Alzheimer's Disease Patient - Preliminary Research (ADAPT)

Depression | Alzheimer Disease

Japan
GlaxoSmithKline

Completed

A Fixed Dose Study of 323U66 SR in the Treatment of Major Depressive Disorder (MDD)

Depressive Disorder, Major

Korea, Republic of, Japan
Janssen Pharmaceutical K.K.

Completed

A Study to Evaluate the Efficacy, Safety and Tolerability of Fixed Doses of Intranasal Esketamine in Japanese Participants With Treatment Resistant Depression

Depression

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Venlafaxine ER Long-Term Extension Study for Major Depressive Disorder (MDD)

Major Depressive Disorder

Japan
Sumitomo Pharma America, Inc.

Terminated

A Clinical Study of an Investigational Drug for the Treatment of Major Depressive Episode Associated With Bipolar I Disorder.

Depressive Episodes, Bipolar I Depression

United States, Bulgaria, Japan, Romania, Canada, Slovakia
Otsuka Pharmaceutical Co., Ltd.

Completed

Assess the Efficacy and Safety of ASC-01 in Patients With Major Depressive Disorder

Major Depressive Disorder

Australia, Taiwan, Malaysia, Korea, Republic of, Japan
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression (SYNAPSE)

Treatment Resistant Depressive Disorder

United States, Japan, Belgium
Sumitomo Pharma America, Inc.

Terminated

A Clinical Trial to Determine the Long-term Safety and Tolerability of an Investigational Drug in People With Major Depressive Episode Associated With Bipolar I Disorder (Bipolar I Depression).

Depressive Episodes, Bipolar I Depression

United States, Bulgaria, Japan
Naurex, Inc, an affiliate of Allergan plc

Terminated

Study of Rapastinel as Monotherapy in Patients With Major Depressive Disorder (MDD)

Depressive Disorder, Major

Slovakia, Poland, Hungary, Japan, Russian Federation

3

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